• Molecules and Cells
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• v.38 no.6
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• pp.496-505
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• 2015

A variant peak was detected in the analysis of RP-HPLC of rHu-EPO, which has about 7% relative content. Fractions of the main and the variant peaks were pooled separately and further analyzed to identify the molecular structure of the variant peak. Total mass analysis for each peak fraction using ESI-TOF MS shows differences in molecular mass. The fraction of the main peak tends to result in higher molecular masses than the fraction of the variant. The detected masses for the variant are about 600-1000 Da smaller than those for the main peak. Peptide mapping analysis for each peak fraction using Asp-N and Glu-C shows differences in O-glycopeptide profiles at Ser126. The O-glycopeptides were not detected in the fraction of the variant. It is concluded that the variant peak is non-O-glycosylated rHu-EPO and the main peak is fully O-glycosylated rHu-EPO at Ser126.

• Journal of Elementary Mathematics Education in Korea
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• v.18 no.2
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• pp.237-255
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• 2014

The purpose of this study is to investigate elementary school students' understanding the concept and operations of decimal fraction. The survey research was performed for this study. This survey was done by selecting 156 students. Questionnaire were made in five areas with reference to the 2007 revised mathematics curriculum. Five areas were the concept of decimal fraction, the addition, the subtraction, the multiplication and the division of decimal fraction. The results of such analysis are as follow: The analyzed result of understanding about concepts and operation of decimal fraction showed a high rate of correct answer, more than 85%. Students thought that multiplication and division of decimal fraction is more difficult than addition, subtraction, concept of decimal fraction. As the learning about concepts and operation of decimal fraction progress, the learning gap is bigger. Effort to reduce the learning deficits are needed in the lower grades. Mathematics is the study of the hierarchical. Learning deficits in low-level interfere with the learning in next-level. Therefore systematic supplementary guidance for a natural number and decimal fraction in low-level is needed. And understanding concepts and principles of calculations should be taught first.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.31 no.1 s.256
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• pp.89-96
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• 2007

A volume integral equation method (VIEM) is applied for the effective analysis of plane elastostatic problems in unbounded solids containing single isotropic inclusion of two different shapes considering composite fiber volume fraction. Single cylindrical inclusion and single square cylindrical inclusion are considered in the composites with six different fiber volume fractions (0.25, 0.30, 0.35, 0.40, 0.45, 0.50). Using the rule of mixtures, the effective material properties are calculated according to the corresponding composite fiber volume fraction. The analysis of plane elastostatic problems in the unbounded effective material containing single fiber that covers an area corresponding to the composite fiber volume fraction in the bounded matrix material are carried out. Thus, single fiber, matrix material with a finite region, and the unbounded effective material are used in the VIEM models for the plane elastostatic analysis. A detailed analysis of stress field at the interface between the matrix and the inclusion is carried out for single cylindrical or square cylindrical inclusion. Next, the stress field is compared to that at the interface between the matrix and the single inclusion in unbounded isotropic matrix with single isotropic cylindrical or square cylindrical inclusion. This new method can also be applied to general two-dimensional elastodynamic and elastostatic problems with arbitrary shapes and number of inclusions. Through the analysis of plane elastostatic problems, it will be established that this new method is very accurate and effective for solving plane elastic problems in unbounded solids containing inclusions considering composite fiber volume fraction.

• Korean Journal of Pharmacognosy
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• v.48 no.1
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• pp.46-50
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• 2017

This study was conducted to investigate the antioxidative activities and tyrosinase inhibition effects of fractions from the distilled water extract of Inonotus obliquus. Moreover, GC-MS based analysis with trimethylsilyl (TMS) derivatization was carried out for active compound in the extract of I. obliquus. In DPPH radical scavenging ability, $SC_{50}$ values of the ethyl acetate fraction was 0.393 mg/ml as a result of the most effective than other fractions. Meanwhile, aqueous fraction showed higher effect in tyrosinase inhibitoty activity. In GC-MS based analysis with TMS derivatization, 7 compounds including syringic acid, vanillic acid and protocatechuic acid were observed in ethyl acetate fraction, and oxalic acid is the main compound in aqueous fraction. As a result, it was confirmed that oxalic acid in aqueous fraction from the distilled water extract of I. obliquus was a compound showing tyrosinase inhibition effect.

• Education of Primary School Mathematics
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• v.21 no.2
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• pp.111-130
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• 2018

In this study, I compared and analyzed the contents of Korean, Japanese, Singapore, American, and Finnish textbooks about fraction which is one of the important and difficult concepts in elementary school mathematics. This is aimed to get the implications for meaningful fractional teaching and learning by analyzing the advantages and disadvantages of the methods and time of introducing the concept because fraction has the diversity of the sub-concepts and the introducing methods or process. As a result of the analysis, the fraction was introduced as part-whole(area) in all five countries' textbooks, but the use of number line, conversion between improper fraction and mixed number, whether to deal with part-whole(set) model. Furthermore, there are differences in the methods in obtaining of the equivalent fraction and the order of arrangement in comparison of fraction. Through this analysis, we discussed the reconsideration of the introducing contexts of fractions, the use of number line when introducing fractions, and the problem of segmentation and classification of contents.

• Journal of Educational Research in Mathematics
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• v.19 no.1
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• pp.25-43
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• 2009

The fraction concept consists of various meanings and is one of the abstract and difficult in elementary school mathematics. This study intends to find out the implication for introducing the fraction concept by comparing mathematics textbooks of Korea and Singapore. Both countries' students peformed well in recent TIMMSs. Some implications are as follows; The term 'equal' is not defined and the results of various 'equal partitioning' activities can not easily examined in Korea's mathematics textbook. And contexts of introducing fractions as a quotient and a ratio are unnatural in Korea's mathematics textbook in comparison with Singapore's mathematics textbook. So these ideas should be reconsidered in order to seek the direction for improvement of it. And Korea's textbooks need the emphasis on the fraction as a measure and on constructing fraction concept by unit fraction.

• Journal of the Korean Society of Industry Convergence
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• v.4 no.1
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• pp.3-9
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• 2001

Many products related to automobile and airplane have been manufactured by semi-solid process. There are many parameters in semi-solid process such as punch velocity, die temperature, and solid fraction of material. Among these parameters, solid fraction of material is one of the most important factors to determine quality of product. To obtain solid fraction of a certain semi-solid product is very necessary and useful for inspecting and analyzing the product. In this paper, image analysis program for microstructure by semi-solid forming process has been developed with the simple apparatus such as a personal computer and scanner, instead of expensive image analyzer.

• Korean Journal of Pharmacognosy
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• v.48 no.3
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• pp.208-212
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• 2017

In this study, analysis of active compounds that are believed to be highly relevant to antioxidant activity was carried out on the methanol extract and its solvent fractions of Corni fructus. The DPPH radical scavenging activity for the comparison of antioxidant activity was higher in order of aqueous fraction > methanol extract > ethyl acetate fraction > n-hexane fraction. It is similar to the order of total polyphenol contents in the samples. As a result of LC-MS analysis, phenolic acid compounds such as caffeic acid, gallic acid and chlorogenic acid and lognin, which is known as a representative active ingredient of Corni fructus, were identified as active compounds. And the antioxidative activity and the total polyphenol content of the extracts and solvent fractions were found to be related to the contents of the compounds. Particularly, it was confirmed that phenolic acid such as caffeic acid contributes to the antioxidative activity of the aqueous fraction of Corni fructus methanol extract.

• 전기의세계
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• v.13 no.4
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• pp.16-24
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• 1964

The dynamic equations of the void fraction and the water velocity in boiling region of the BWR reactor core are derived. And these equations are approximated to be able to set on an PACE analog computor. The transient analysis and the frequency response obtained by analog computer are compared with other by digital computor.

• Research in Mathematical Education
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• v.16 no.4
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• pp.217-232
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• 2012

While many studies on early algebra have been conducted, there have been only a few studies on the operation sense as the fundamental element of algebraic thinking, especially the fraction operation sense. This study explored the dimensions of fraction operation sense and then investigated students' fraction operation sense. A total of 183 of sixth graders were surveyed and 5 students who showed high operation sense were clinically interviewed in order to analyze their algebraic thinking in detail. The results showed that students had a tendency to use direct calculation or employ inappropriate operation sense rather than to use the structure of operation or the relation between operations on the basis of algebraic thinking. This study implies that explicit instruction on early algebra is necessary from the elementary school years.