• International Journal of Advanced Culture Technology
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• 제8권4호
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• pp.82-88
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• 2020

With the development of medical care in the 21st century and the rapid development of the 4th industry, electronic devices and household goods taking into account the physical and mental aging of the silver generation have been developed, and apps related to health and health are generally developed and operated. The apps currently used by the silver generation are a form that provides information on diseases by focusing on prevention rather than treatment, such as safety management apps for the elderly living alone and methods for preventing diseases. There are not many apps that provide information on foods that have a direct effect and nutrients in that food, and research on apps that can obtain information about individual foods is insufficient. In this paper, we propose an app that analyzes food factors and provides self-medication for health promotion of the silver generation. This app allows the silver generation to conveniently and easily obtain information such as nutrients, calories, and efficacy of food they need. In addition, this app collects/categorizes healthy food information through a textom solution-based crawling agent, and stores highly relevant words in a data resource. In addition, wide deep learning was applied to enable self-medication recommendations for food. When this technique is applied, the most appropriate healthy food is suggested to people with similar eating patterns and tastes in the same age group, and users can receive recommendations on customized healthy foods that they need before eating. This made it possible to obtain convenient healthy food information through a customized interface for the elderly through a smartphone.

• 한국식품영양과학회지
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• 제38권10호
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• pp.1317-1323
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• 2009

당유자 과피(GGP) 80% 에탄올 추출물을 4종의 암세포에 (피부암, 대장암, 유방암 및 혈액암) 처리하여 증식 억제 활성을 측정한 결과, 혈액암 HL60 세포에서 높은 증식 억제 활성을 보였다. 이에 CGP 추출물이 HL60 세포에 대한 apoptosis 유도에 따른 세포 증식 억제 활성을 조사하였다. Apoptosis 유도의 첫 단계인 막 투과성을 측정한 결과, confocal image와 flow cytometry에서 CGP를 처리하였을 때 탈분극 현상에 따른 막 투과성이 증가하였고 세포내 핵을 hoechst 33342를 이용하여 염색하였을 때 apoptosis가 일어났을 때 나타나는 전형적인 형태의 apoptotic body가 농도 의존적으로 증가하는 것을 확인할 수 있었으며 flow cytometry를 통하여 세포 주기를 측정하였을 때 DNA-hypodiploid 형태의 sub-G1가 CGP 농도 의존적으로 증가하는 것을 확인할 수 있었다. Apoptosis 유도 기전을 western blot으로 측정한 결과를 보면, CGP 추출물을 혈액암 HL60 세포에 처리하였을 때 Bcl family의 anti-apoptotic Bcl-2 단백질의 감소와 pro-apoptotic Bax 단백질의 증가로 인하여 하위 기전인 caspase-3가 활성화되었으며, 이 활성화로 인하여 apoptosis 유도에 직접적으로 관여하는 PARP 단백질을 활성화시키면서 apoptosis를 유도하였다. 따라서 당유자 과피는 항암과 관련되어진 기능성식품 및 소재 개발 원료로서 개발이 가능하리라고 사료된다.

• 한국식품영양과학회지
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• 제38권10호
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• pp.1310-1316
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• 2009

당유자 과피를 식품미생물인 효모를 이용하여 발효 후 80% 에탄올로 추출하여 발효 전과 후의 플라보노이드 함량 및 성분 변화와 항산화 활성의 차이를 비교 분석하였다. LC/MS를 통한 플라보노이드 분석 결과, 발효 후 추출물에서 neohesperidin과 naringin의 함량 변화는 큰 차이가 없었으나, hesperidin과 일부 플라보노이드 성분은 감소하였으며, 특히 3',4',5',5,7-pentamethoxyflavone은 발효 후에 그 함량이 크게 감소하였다. 이에 반하여 친수성 unknown 화합물들이 크게 증가하는 것을 LC/MS을 통하여 확인할 수 있었다. 이는 효모를 통한 발효과정 중에 플라보노이드 성분이 다른 형태로 전환되었으며, 이렇게 전환되어진 성분들을 함유한 FCGP는 CGP보다 DPPH, hydroxyl, alkyl 및 hydrogen peroxide 소거활성 등과 같은 항산화 활성을 크게 증가시켰다. 결론적으로 효모를 이용하여 당유자 과피를 발효시킴으로써 생리활성 성분의 일부를 전환시킴으로써 항산화 활성 등과 같은 기능성을 향상시킬 수 있어, 향후 당유자 과피의 발효에 의한 다양한 건강기능식품으로서의 개발이 가능한 것으로 사료된다.

• 한국수산과학회지
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• 제42권5호
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• pp.417-425
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• 2009

The potential utility of fish scales to the functional food industry has been investigated due to its antioxidant and antihypertensive characteristics. In this study, we report on the reactive oxygen species (ROS) scavenging and angiotensin I converting enzyme (ACE) inhibitory activities of gelatin hydrolysates processed from Branchiostegus japonicus scales, which are also high in protein content (about 46.1%). We prepared the enzymatic gelatin hydrolysates with four proteases (${\alpha}$-chymotrypsin, Alcalase, Neutrase and trypsin) from B. japonicus scale gelatin, which was prepared according to different reaction times, substrate/enzyme ratios and substrate concentrations. The enzymatic hydrolytic degrees of the gelatin increased time-dependently up to 6 hrs, while the Alcalase gelatin hydrolysates showed the highest hydrolysis degrees compared to the others. Furthermore, gelatin hydrolysates of Neutrase and ${\alpha}$-chymotrypsin showed the highest DPPH radical and $H_2O_2$ scavenging activities ($IC_{50}$ value; 9.18 mg/mL and 9.74 mg/mL), respectively. However, the activities were not significant (P<0.05). We also observed that the four gelatin hydrolysates significantly increased ACE inhibitory activities from approximately 20% to 60% (P<0.05), Among them, the Alcalase gelatin hydrolysates showed the higher ACE inhibitory activity ($IC_{50}$ value; 0.73 mg/mL) compared to the others. These results suggest that the enzymatic gelatin hydrolysates prepared from B. japonicus scales may possess a potentially useful function as an ACE inhibitory agent. As such, the utility of B. japonicus scales should be given due consideration for application in the functional food industry.

• 한국식품과학회지
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• 제45권1호
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• pp.40-46
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• 2013

SPP를 첨가하여 제조한 빵(dinner roll) 반죽의 pH는 대조구와 실험구 사이에 차이가 없었다. SPP 첨가량과 반죽의 밀도 사이에는 강한 양의 상관관계를, 반죽의 발효팽창력 사이에는 음의 상관관계를 나타내었다. Dinner roll의 굽기손실율은 SPP의 첨가량이 증가할수록 감소하였으나, 비용적은 차이가 없었다. Dinner roll crust의 L value, b value, chroma 및 Hue angle은 대조구보다 SPP 첨가구가 유의적으로 낮았고, a value는 대조구보다 SPP 첨가구가 유의적으로 높았다. Crumb의 L value와 Hue angle은 대조구보다 SPP 첨가구가 유의적으로 낮았고, a value, b value 및 chroma는 대조구보다 SPP 첨가구가 유의적으로 높았다. SPP 첨가량과 dinner roll의 hardness 및 cohesiveness 사이에는 강한 양의 상관관계가 있었으나, springiness 및 chewiness와는 상관관계가 형성되지 않았다. Streptozotocin 투여로 당뇨병이 유발된 흰쥐에 SPP가 첨가된 dinner roll을 4주간 섭취시킨 결과, SPP 첨가구의 혈당 농도가 대조구보다 유의적으로 감소하였고, 이는 SPP에 함유된 ${\beta}$-carotene 때문인 것으로 사료되었다.

• 한국응용과학기술학회지
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• 제33권2호
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• pp.255-263
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• 2016

식품부패미생물에 대한 감초추출물의 항균력을 확인하고 유효성분을 분리한 후 그 구조를 확인 하였다. 감초추출물은 대표적인 항균제인 메타중아황산칼륨과 myconazole과 비슷한 항균 활성을 나타내었다. 용매분획을 실시한 결과 chloroform fraction이 가장 항균활성이 높은 것으로 나타났다. 이에 chloroform분획을 silica gel column chromatography를 통해 분리하여 항균활성이 가장 큰 분획물인 KC를 분리하였다. 이 화합물은 ESI-MS 와 $^1H$-NMR, $^{13}C$-NMR 결과로부터 활성물질의 구조를 동정하였으며 그 결과 KC는 (R)-glabridin인 것으로 확인하였다.

• 동아시아식생활학회지
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• 제18권2호
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• pp.165-171
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• 2008

The purpose of this study was to measure tourists' preference for alternative restaurants with different combinations of attribute levels: grown area logo, origin description, traditional food, fusion food, national food, and price. A total of 210 questionnaires were completed. A conjoint experimental method was used to develop hypothetical restaurants, and an ordinal probit model was used to measure the effects of the attribute levels on tourists' preference. The ordinal probit model analysis results for the data indicated an excellent model fit. The effects of the attribute levels on tourists' preferences were statistically significant. As expected, estimates of the marginal willingness to pay were statistically significant Moreover, the tourists were more willing to pay for grown area logo as compared to the other attribute levels. The tourists also considered the grown area logo as a very important attribute. Withe regard to developing and testing conjoint models in the design of choice experiments involving multifactor alternatives, this study may approach a deeper understanding of the conjoint experiment. Greater understanding of the conjoint experiment can improve the managerial diagnoses of the problems as well as the opportunities for different marketing strategies including local branding programs and menu development and marketing communications.

• Food Quality and Culture
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• 제2권2호
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• pp.85-88
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• 2008

We have investigated the effects of cottonseed extract on the proliferation, differentiation and lipopolysaccharide (LPS)-induced production of local factors in murine clonal osteoblastic MC3T3-E1 cells. Ethanol extract of cotton seed ($4{\sim}63{\mu}g/mL$) significantly increased the proliferatin of MC3T3-E1 cells (p<0.05). Moreover, cottonseed extract ($10{\sim}50{\mu}g/mL$) caused a significant elevation of alkaline phosphatase (ALP) activity and collagen content in the cells. Lipopolysaccharide (LPS) is a potent stimulator of bone resorption in inflammatory diseases. We examined the effect of cottonseed extract on the LPS-induced production of tumor necrosis factor a (TNF-$\alpha$) and nitric oxide (NO) in MC3T3-E1 cells. Treatment with cottonseed extract ($10{\sim}50{\mu}g/mL$) decreased the $5{\mu}g/mL$ LPS-induced production of TNF-$\alpha$ and NO in osteoblasts, suggesting that the antiresorptive action of cottonseed extract may be mediated by decrease in these local factors. This study suggests that cottenseed may contribute to antiresorptive action against osteoblastic cells, resulting in a beneficial effect in promoting the function of osteoblastic cells.

• 한국식품조리과학회지
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• 제27권2호
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• pp.97-110
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• 2011

The purpose of this study was to investigate the influence of a cook's understanding about organizational fairness on job satisfaction and business performance at family restaurants in Seoul. Frequency analysis, reliability analysis, factor analysis, and SEM were applied to analyze the data. First, a confirmatory reliability analysis indicated that organizational fairness, job satisfaction, and business performance were sufficient to be used in this investigation. Organizational fairness, job satisfaction and business performance had generally significant relationships by implementing SEM. According to the results, distributive fairness (p< 0.001), procedural fairness (p< 0.05) and interactive fairness (p< 0.05) had positive influence on cook's job satisfaction. Job satisfaction had a positive influence on financial (p< 0.05) and non-financial performance (p< 0.001). Therefore, for the purposes of food-service companies' continuous increases in business performance and competition are generally necessary to suitably manage the fairness of various policies such as job stability, promotions, impartial distribution of salary, bonus and welfare work, and internal marketing.

• 한국관광식음료학회지:관광식음료경영연구
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• 제9권
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• pp.273-302
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• 1998

INTERNATIONAL MONITORY FUNDS wave swept the Economic structural insolvency lies one upon another with low growth, low trust, low prices, low interest and low employment as[2 down 3 up] phenomenons have been distinguished and low enterprise a control of structures due to forecasting 200 million unemployment, including 600 million unemployed the head of a family population have a difficulty in their life. Only way to give them hope is through the commencement of an enterprises to have 2nd career development. But end of 1995, 467,00 dining out companies have been established and recently business are in depression. There are many business conditions of change of business or reduce operations, if unemployment populations of 5%, 100,000 peoples doing the commencement of an enterprises, enormous number of dining out companies will be increased and the competition will be fierce, especially those who have short knowledge and experience doing the commencement of an enterprises have high failure than success which will give a problems to society. Our study is to make the commencement of an enterprise to reducing the faiure and to be successful for main point to successful commencement of an enterprise, the established can self capability and mental condition, the main important factor is types of industry selection, successful and those established who takes this conditions will very carefully inspect various matters by scientifically and rationally mind industrys propulsion graphs and open official fixture graphs will framing detail factors. One by inspect the reduction of failure, and successful commencement of an enterproses mind industry have been studied.