• Title/Summary/Keyword: flow cell

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The Effect of Transverse Vibration on Red Blood Cell Aggregation and Blood Viscosity

  • Shin, Se-Hyun;Ku, Yun-Hee;Park, Myung-Su;Suh, Jang-Soo
    • International Journal of Vascular Biomedical Engineering
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    • v.1 no.2
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    • pp.4-12
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    • 2003
  • The present study investigated the effect of transverse vibration on the hemorheological characteristics of blood using a newly designed pressure-scanning capillary viscometer. As vibration was applied, aggregated blood cells (rouleaux) were disaggregated. The range of vibration frequency and amplitude are $0{\sim}100\;Hz$ and $0{\sim}0.8\;mm$, respectively for a capillary diameter 0.84 mm. As vibration increased, blood viscosity initially increased and tended to decrease. In order to delineate the unexpected results, the present study proposed two counteracting mechanisms of vibration related with red blood cell (RBC) aggregation affecting hemo-rheological properties. One is the reduction of RBC aggregation due to vibration causing an increase of blood viscosity. The other is forced cell migration due to the transverse vibration, which in turn forms a cell-free layer near the tube wall and causes a decrease of flow resistance.

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Numerical Evaluation of a Radially Variable Cell Density Strategy for Improving Light-off Performance: Focusing on Light-off Catalyst (자동차용 촉매변환기의 활성화 성능 향상을 위한 횡방향 가변 셀 밀도법의 수치적 평가: 활성화 촉매변환기를 중심으로)

  • 정수진;김우승
    • Transactions of the Korean Society of Automotive Engineers
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    • v.10 no.1
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    • pp.115-124
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    • 2002
  • The optimum design of auto-catalyst needs a good compromise between the pressure drop and flow distribution in the monolith. One of the effective methods to achieve this goal is to use the concept of radially variable cell density. However, there has been no study of evaluating the usefulness of this method on light-off catalyst. We have computationally investigated the effectiveness of variable cell density technique applied to the light-off catalyst using a three-dimensional integrated CFD model. in which transient chemical reacting calculations are involved. Computed results show that variable cell density technique can reduce the accumulated emissions of CO and HC during the early 100sec of FTP cycle by 86.78 and 80.87%, respectively, The effect of air-gap between the monoliths has been also examined. It is found that air-gap has a beneficial effect on reducing pressure drop and cold-start emissions.

Development of Fuel Economy Measurement Method for Hydrogen Fuel Cell Vehicles (수소연료전지자동차 연료소비율 측정방법에 대한 연구)

  • Lim, Jong-Soon;Choi, Young-Tae;Yong, Gee-Joong;Kwon, Hae-Boung;Lee, Hyun-Woo;Maeng, Jeong-Yoel
    • 한국신재생에너지학회:학술대회논문집
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    • 2009.06a
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    • pp.636-639
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    • 2009
  • Fuel consumption measurement of Hydrogen fuel cell vehicle is considerably different form internal combustion engine vehicle such as carbon balance method. A practical method of fuel Consumption measurement has been developed for Hydrogen fuel cell vehicles. There are three method of hydrogen fuel consumption testing, gravimetric, PVT(Pressure, Volume and temperature), and Coriolis mass flow, all of which necessitate physical measurements of the fuel supply. The purpose of this research is to measure the fuel consumption of hydrogen fuel cell vehicles on chassis-dynamometer and to give information when the research is intended to develop method to measure hydrogen fuel consumption.

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A Study of High-efficiency me-silicon solar cells for SiNx passivation (SiNx passivation에 따른 Solar Cell의 효율향상에 관한 연구)

  • Ko, Jae-Kyung;Lim, Dong-Gun;Kim, Do-Young;Park, Sung-Hyun;Park, Joong-Hyun;Yi, Jun-Sin
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2002.07b
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    • pp.964-967
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    • 2002
  • The effectiveness of silicon nitride SiNx surface passivation is investigated and quantified. This study adopted single-layer antireflection (SLAR) coating of SiNx for efficiency improvement of solar cell. The silicon nitride films were deposited by means of plasma enhanced chemical vapor deposition (PECVD) in planar coil reactor. The process gases used were pure ammonia and a mixture of silane and helium. The thickness and the refractive index on the films were measured by ellipsometry and chemical bonds were determined by using an FT-IR equipment. This films obtained were analyzed in term of hydrogen content, refractive index for gas flow ratio $(NH_3/SiH_4)$, and efficiency of solar cell. The polycrystalline silicon solar cells passivated by silicon nitride shows efficiency above 12.8%.

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Induction of Apoptosis by 3-Methoxy-6-Allylthiopyridazine in Human Pancreatic Cancer Cells (3-메톡시-6-알릴치오피리다진의 사람 췌장암 세포 사멸작용)

  • Kang Young Shin;Suh Yeon Won;Kwon Soon-Kyoung;Jeong Choon Sik;Lee Yong Soo
    • YAKHAK HOEJI
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    • v.49 no.4
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    • pp.335-339
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    • 2005
  • In this study we investigated the effect of 3-methoxy-6-allylthiopyridazine on cell growth in BxPC3 and PANC1 human pancreatic cancer cells. The treatment with 3-methoxy-6-allylthiopyridazine for 48h decreased cell viability and induced apoptotic cell death in a dose-dependent manner, assessed by using the MTT assay and the flow cytometry, respectively. These results suggest that 3-methoxy-6-allylthiopyridazine may be a good candidate for the therapeutic management of human pancreatic cancers.

Novel Zero-Current-Switching (BCS) PWM Switch Cell Minimizing Additional Conduction Loss

  • Park, Hang-Seok;Cho, B.H.
    • KIEE International Transaction on Electrical Machinery and Energy Conversion Systems
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    • v.12B no.1
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    • pp.37-43
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    • 2002
  • This paper proposes a new zero-current switching (ZCS) pulse-width modulation (PWM) switch cell that has no additional conduction loss of the main switch. In this cell, the main switch and the auxiliary switch turn on and turn off under zero current condition. The diodes commutate softly and the reverse recovery problems are alleviated. The conduction loss and the current stress of the main switch are minimized, since the resonating current for the soft switching does not flow through the main switch. Based on the proposed ZCS PWM switch cell, a new family of dc to dc PWM converters is derived. The new family of ZCS PWM converters is suitable for the high power applications employing IGBTs. Among the new family of dc to dc PWM converters, a boost converter was taken as an example and has been analyzed. Design guidelines with a design example are described and verified by experimental results from the 2.5㎾ prototype boost converter operating at 40KHz.

Dyamic Modeling and Analysis of Air Supply System for Vehicular PEM Fuel Cell (고분자 전해질형 연료전지 자동차의 급기 시스템의 동적 모델링 및 분석)

  • Jang, HyunTak
    • Transactions of the Korean hydrogen and new energy society
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    • v.15 no.3
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    • pp.175-186
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    • 2004
  • In this paper, we developed the dynamic model of a fuel cell system suitable for controller design and system operation. The transient phenomena captured in the model include the flow characteristics and inertia dynamics of the compressor, the intake manifold filling dynamics, oxygen partial pressures and membrane humidity on the fuel cell voltage. In the simulations, we paid attention to the transient behavior of stack voltage and compressor pressure, stoichiometric ratio. Simulation results are presented to demonstrate the model capability. For load current following, stack voltage dynamic characteristics are plotted to understand the Electro-chemistry involved with the fuel cell system. Compressor pressure and stoichiometric ratio are strongly coupled, and independent parameters may interfere with each other, dynamic response, undershoot and overshoot.

Performance Characterization of Polymer Electrolyte Membrane Direct Methanol Fuel Cell on the Various Operation Conditions (운전조건에 따른 고분자 직접메탄올 연료전지 성능 특성)

  • Jung, Doo-Hwan;Lee, Chang-Hyeong;Shin, Dong-Ryul
    • Proceedings of the KIEE Conference
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    • 1996.07c
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    • pp.1409-1411
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    • 1996
  • Direct Methanol Fuel Cell(DMFC) using Pt-Ru electrocatlayst and Nafion menbrane can provide high performance if operating conditions are well designed. In this study, operating temperature, pressure, and fuel flow rate were changed to obtain optimum operating conditions of DHFC single cell. Performance of DMFC were increased by the increase of operating temperature. The concentration of fuel methanol was 2.0M $CH_{3}OH$ and pressure difference of cathode and anode was 2 atm were showed maximum performance of DMFC single cell with showing the current density of 160 $mA/cm^2$ at 0.2V cell voltage.

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Development of an integrative cardiovascular system model including cell-system and arterial network (세포-시스템 차원의 혈류역학적 심혈관 시스템 모델의 개발)

  • Shim, Eun-Bo;Jun, Hyung-Min
    • 한국전산유체공학회:학술대회논문집
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    • 2008.03b
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    • pp.542-546
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    • 2008
  • In this study, we developed a whole cardiovascular system model combined with a Laplace heart based on the numerical cardiac cell model and a detailed arterial network structure. The present model incorporates the Laplace heart model and pulmonary model using the lumped parameter model with the distributed arterial system model. The Laplace heart plays a role of the pump consisted of the atrium and ventricle. We applied a cellular contraction model modulated by calcium concentration and action potential in the single cell. The numerical arterial model is based upon a numerical solution of the one-dimensional momentum equations and continuity equation of flow and vessel wall motion in a geometrically accurate branching network of the arterial system including energy losses at bifurcations. For validation of the present method, the computed pressure waves are compared with the existing experimental observations. Using the cell-system-arterial network combined model, the pathophysiological events from cells to arterial network are delineated.

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Single-cell Electroporation and Gene Transfection using MEMS-based Microdevice with Cantilever-type Microelectrode (멤스 기반의 캔틸레버 형 전극을 가진 마이크로 디바이스를 이용한 단일세포의 Electroporation 및 유전자 Transfection)

  • Cho, Young-Hak;Kim, Beom-Joon
    • Journal of the Korean Society for Precision Engineering
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    • v.27 no.5
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    • pp.85-91
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    • 2010
  • In this paper, we present details on fabrication of single-cell electroporation microdevice, practical experiments of single-cell electroporation with our fabricated microdevice. Also, the continuous electroporation for the continuous flow of cells is used for high-throughput electroporation. The delivery efficiency and cell viability tests are provided and the successful GFP transfection into cells is also evaluated with a fluorescent microscope after electroporation. This device enables to reduce the size of samples and thus the use of small amount of reagents. Also, it makes it possible to permit to avoid cell discrimination (transfected cells versus non-transfected cells) encountered when traditional bulk electroporation is held.