• Environmental Sciences Bulletin of The Korean Environmental Sciences Society
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• 제4권4호
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• pp.227-230
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• 2000

Bunker-A oil-degrading microorganisms were isolated from a marine environment using an enrichment culture technique. The isolated strain EL-081K was identified as the genus Acinetobacter based on the results of morphological, culture, and biochemical tests. The optimal temperature and initial pH for bunker-A oil degradation were $25^{\circ}C$ and 7.0, respectively, including aeration. The optimal medium composition for the degradation of bunker-A oil by Acinetobacter sp. EL_O81K was 10 ml/l bunker-A oil as the carbon source and 0.1% (NH$_4$)$_2$SO$_4$as the nitrogen source. Under the above conditions, the biodegradability of bunker-A oil was 38% after 96 hours of incubation. The addition of detergent did not increase the bunker-A oil degradation.

• 대한가정학회지
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• 제39권10호
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• pp.141-152
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• 2001

The purpose of this study was to investigate the after school program in the rural community and the demands of children, parents and teachers for the after school program. Elementary school teachers, parents and children in the farming areas an over the 9 providences responded to the questionnaires developed by the researchers. Conclusions were that almost teachers, parents and children wanted and needed after school program. The after school care's current status was low with lack of teachers for the after school program and financial support. The teachers and parent wanted learning enrichment and talent education-oriented after school program rather than child care-oriented. The most wanted program contents by teachers, parents and children were computer education, English, arts, social development.

• Genomics & Informatics
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• 제5권1호
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• pp.24-29
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• 2007

Computational virtual screening has become an essential platform of drug discovery for the efficient identification of active candidates. Moleculardocking, a key technology of receptor-centric virtual screening, is commonly used to predict the binding affinities of chemical compounds on target receptors. Despite the advancement and extensive application of these methods, substantial improvement is still required to increase their accuracy and time-efficiency. Here, we evaluate several advanced structure-based virtual screening approaches for elucidating the rank-order activity of chemical libraries, and the quantitative structureactivity relationship (QSAR). Our results show that the ensemble-average free energy estimation, including implicit solvation energy terms, significantly improves the hit enrichment of the virtual screening. We also demonstrate that the assignment of quantum mechanical-polarized (QM-polarized) partial charges to docked ligands contributes to the reproduction of the crystal pose of ligands in the docking and scoring procedure.

• BMB Reports
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• 제46권2호
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• pp.97-102
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• 2013

The use of various cancer cell lines can recapitulate known tumor-associated mutations and genetically define cancer subsets. This approach also enables comparative surveys of associations between cancer mutations and drug responses. Here, we analyzed the effects of ~40,000 compounds on cancer cell lines that showed diverse mutation-dependent sensitivity profiles. Over 1,000 compounds exhibited unique sensitivity on cell lines with specific mutational genotypes, and these compounds were clustered into six different classes of mutation-oriented sensitivity. The present analysis provides new insights into the relationship between somatic mutations and selectivity response of chemicals, and these results should have applications related to predicting and optimizing thera-peutic windows for anti-cancer agents.

• 대한기계학회논문집A
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• 제28권8호
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• pp.1196-1202
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• 2004

A meshfree multi-scale method has been presented for efficient analysis of elasto-plastic problems. From the variational principle, problem is decomposed into a fine scale and a coarse scale problem. In the analysis only the plastic region is discretized using fine scale. Each scale variable is approximated using meshfree method. Adaptivity can easily and nicely be implemented in meshree method. As a method of increasing resolution, partition of unity based extrinsic enrichment is used. Each scale problem is solved iteratively. Iteration procedure is indispensable for the elasto-plastic deformation analysis. Therefore this kind of solution procedure is adequate to that problem. The proposed method is applied to Prandtl's punch test and shear band problem. The results are compared with those of other methods and the validity of the proposed method is demonstrated.

• 한국수산과학회지
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• 제44권3호
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• pp.207-215
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• 2011

An endosulfan degrading bacterial strain, K-1321, was isolated by endosulfan-enrichment culture from a seaside sediment collected at Dadaepo Beach, Busan, Korea. The strain was identified as a Serratia sp. based on the results of morphological, biochemical and 16S rDNA homology analyses. Serratia sp. K-1321 was able to completely degrade 50 ppm endosulfan in culture media and soil within 6 weeks at $25^{\circ}C$. GC/MS analysis revealed that endosulfan diol was an intermediate of the bacterial endosulfan degradation. Considering the above results, we concluded that Serratia sp. K-1321 utilized endosulfan as a carbon source and metabolized endosulfan via a less toxic pathway, such as the formation of endosulfan diol as an intermediate.

• 한국주조공학회지
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• 제16권2호
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• pp.149-157
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• 1996

Several aluminum based alloys were fabricated by a twin roll strip casting mill. As-cast microstructures and microsegregations of these aluminum alloys were investigated by means of optical microscope, scanning electron microscope and electron probe micro analysis. Clear distinction on microsegregation among the alloy systems was observed, that is, A1235 and A8011 alloys showed diffused segregation in the middle of the strip, while A3003 and A5086 alloys revealed a centerline segregation consisted of lamellar structure. Above center line segregation was resulted from enrichment of the alloying elements such as Mn, Fe, Cu, Si and eutictic reaction in central region of the alloy strip.

• 대한기계학회논문집B
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• 제28권12호
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• pp.1625-1631
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• 2004

Investigation on Flue Gas Recirculation(FGR) flame and Fuel Injection Recirculation(FIR) flame was performed with numerical method. Quantitative Reaction Path Diagram(QRPD) is utilized to compare the different chemistry effects between FGR flame and FIR flame. In order to compare flamelets in various oxygen-enrichment conditions reasonably, the adiabatic flame temperature and Damkohler number were held fixed by modulating the amount of diluents to fuel and oxidizer stream and by varying global strain rate of flame respectively. Basic flame structures were compared and characteristics of CH$_4$ decomposition and NO formation were analyzed based on QRPD analysis between FGR flame and FIR flame.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 추계학술대회
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• pp.1870-1875
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• 2003

Optimization has been used in many engineering problems and must be one of the essential components during design process now. It is the process of maximizing the performance called an objective function of a system while satisfying some constraints, so finite element method is generally required in order to obtain these values during optimization. However, there are some difficulties to obtain them by means of FEM, where the changes of design variables cause the distortion and the regeneration of mesh that may result in inaccuracy and inefficiency. In order to overcome this problem, this paper proposed an alternative that the eXtended FEM introduced and developed by Ted Belytschko was applied to the optimization process because the key points of the X-FEM lie in that the discontinuity can be represented independently on the mesh by a function called in an enrichment function.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2002년도 하계학술대회 논문집 C
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• pp.1724-1726
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• 2002

A novel ozonizer has been developed using a high-frequency surface discharge and a high purity alumina ceramic as its dielectric component. A thin ceramic layer, cylindrical in form, is adhered by a film-like induction electrode. An ac exciting voltage of frequency to 0.6 kHz from 1.0 kHz and $6{\sim}9kV$ peak-to-peak is applied between the electrodes to produce a stable high-frequency silent discharge for generation of ozone. A substantial reduction of the exciting voltage is also enabled by using a thin alumina ceramic layer. As a result, the ozonizer can easily produce ozone concentration($128g/m^2$ for oxygen) and power efficiency(360g/kWh for oxygen) without using a special enrichment means.