• Journal of Korean Academy of Nursing
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• v.31 no.5
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• pp.858-870
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• 2001

Purpose: This study was to compare changes in health behaviors, motivational factors, cardiovascular risk factors, and functional status (SIP) after implementing the 6-month motivation-enhancing program to institutionalized elderly women. Methods: Sixty-four elderly women participated. Face to face interviews with blood sampling and anthropometric assessment were conducted at the pretest, 10 weeks and 6 months during the program. Results: 1. The program participants showed significantly better health behaviors over 6 months. The mean motivational level was also significantly improved, especially for perceived benefits, perceived barriers, and emotional salience. 2. The mean of cardiovascular risk factors for the participants was 21.8 at the level of low to moderate risk. After completing the program, total risk score was significantly decreased to 18.7 at 10 weeks, and further to 17.7 at 6 months. A significant reduction was also found in HDL and LDL-cholesterol levels, blood pressure, obesity, inactivity, and stress. 3. The functional status (SIP) was 11% at the baseline and significantly changed in positive direction at 10 weeks(M=9.3) and at 6 month(M=6.3). The significant improvement was also found in physical and psychosocial dimensions and sleep/rest dimension. Conclusion: The motivation enhancing program was effective to reduce cardiovascular risks and to improve the functional status of institutionalized elderly women by motivating them to perform better health behaviors.

• Journal of the Korea Society of Computer and Information
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• v.11 no.5 s.43
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• pp.291-297
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• 2006

Enhancing Information Utilization Capability of the elderly is discussed in the level of nation due to the advent of information society and aging. Information divide of the elderly is wider compared with other age groups. It is necessary for the elderly to enhance information ability. Government was implementing the policy for narrowing information divide continually. Dual information divide is brought about by the character of the elderly such as status, economic factor, the level of education. Therefore not only continuous nation's policy but road map is needed for enhancing information utilization capability to computer and internet. Information divide of the elderly would be narrowed out of education, economy, earning, age through those ways.

• Journal of Animal Science and Technology
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• v.63 no.5
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• pp.1159-1168
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• 2021

Ovotransferrin (OTF), an egg protein known as transferrin family protein, possess strong antimicrobial and antioxidant activity. This is because OTF has two iron binding sites, so it has a strong metal chelating ability. The present study aimed to evaluate the improved immune-enhancing activities of OTF hydrolysates produced using bromelain, pancreatin, and papain. The effects of OTF hydrolysates on the production and secretion of pro-inflammatory mediators in RAW 264.7 macrophages were confirmed. The production of nitric oxide (NO) was evaluated using Griess reagent and the expression of inducible nitric oxide synthase (iNOS) were evaluated using quantitative real-time polymerase chain reaction (PCR). And the production of pro-inflammatory cytokines (tumor necrosis factor [TNF]-α and interleukin [IL]-6) and the phagocytic activity of macrophages were evaluated using an ELISA assay and neutral red uptake assay, respectively. All OTF hydrolysates enhanced NO production by increasing iNOS mRNA expression. Treating RAW 264.7 macrophages with OTF hydrolysates increased the production of pro-inflammatory cytokines and the phagocytic activity. The production of NO and pro-inflammatory cytokines induced by OTF hydrolysates was inhibited by the addition of specific mitogen-activated protein kinase (MAPK) inhibitors. In conclusion, results indicated that all OTF hydrolysates activated RAW 264.7 macrophages by activating MAPK signaling pathway.

• Journal of Microbiology and Biotechnology
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• v.31 no.5
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• pp.726-732
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• 2021

In this study, we evaluated the immune-enhancing activity of kimchi-derived Lactobacillus plantarum 200655 on immune suppression by cyclophosphamide (CP) in ICR mice. Animals were fed distilled water or 1×10⁹ colony-forming unit/kg B.W. 200655 or Lactobacillus rhamnosus GG as a positive control for 14 days. An in vivo model of immunosuppression was induced using CP 150 and 100 mg/kg B.W. at 7 and 10 days, respectively. Body weight, spleen index, spleen weight, and gene expression were measured to estimate the immune-enhancing effects. The dead 200655 (D-200655) group showed an increased spleen weight compared to the sham control (SC) group. Similarly, the spleen index was significantly higher than that in the CP-treated group. The live 200655 (L-200655) group showed an increased mRNA expression of tumor necrosis factor-alpha (TNF-α) and interleukin (IL)-6 in splenocytes. Also, the iNOS and COX-2 mRNA expression was upregulated in the L-200655 group compared to the CP-only (SC) group. The phosphorylation of ERK and MAPK was also upmodulated in the L-200655 group. These results indicate that L. plantarum 200655 ameliorated CP-induced immune suppression, suggesting that L. plantarum 200655 may have the potential to enhance the immune system.

• Bulletin of Food Technology
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• v.15 no.4
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• pp.29-35
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• 2002

To prevent the incidence of type food allergies, removal of food allergens by excluding all foodstuffs containing the allergen(s) or disruption of allergen(s) using proteases has been employed. Though allergen- specific digestion with a protease worked well in the preparation of low allergenic goods, it is often difficult to destroy allergenicity without adversely affecting the nutritive value, taste and rheological properties of foods. In the present study, we represented that herbs component contained both allergy- enhancing and inhibiting factors, in addition to llergens. We also reported that herbal component such as epigallocatechingallate (EGCG) and epicatechingallate (ECG) is possible to be allergy- inhibiting factors, but the exact mechanism by which they alleviate allergic response is left to be clarifying. Document of allergy enhancing factors and enrichment of allergy inhibiting factors may provide a new approach to diminish allergenicity of various foodstufffs. Clarification of the allergic reaction modifying mechanism of food components and optimization of the intake of allergy modifying factor are necessary for decrement of allergenicity of conventional food and prevention of incidents of allergic response

• BMB Reports
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• v.50 no.4
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• pp.160-161
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• 2017

Proper maintenance of biological components is crucial for longevity and healthy aging. Although the role of homeostatic maintenance systems for DNA and protein in longevity is established, it remains largely unknown for RNA. In our recent work, we show that nonsense-mediated mRNA decay (NMD) promotes longevity in the roundworm C. elegans by enhancing RNA quality control. We find that the activity of NMD decreases during aging, raising the possibility that RNA quality declines in old animals. We then show that key components of NMD complex are required for prolonged lifespan in C. elegans. In addition, animals with reduced insulin/insulin-like growth factor-1 (IGF-1) signaling (IIS), a representative longevity model, display increased NMD activity. Thus, up-regulation of NMD appears to play crucial roles in longevity conferred by reduced IIS via enhancing mRNA quality control. As both IIS and NMD pathways are evolutionarily conserved, mammals including humans may be equipped with similar RNA quality control systems to achieve longevity.

• Journal of the Korean Physical Society
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• v.73 no.11
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• pp.1684-1690
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• 2018

The layered semiconductors $Bi_2O_2Q$ (Q = S, Se) consists of $Bi_2O_2$ layers sandwiched by Q square nets. On the basis of density functional theory calculations, we examined the thermoelectric properties of $Bi_2O_2S$, $Bi_2O_2Se$ as well as hypothetical structure of $Bi_2O_2$($S_{0.5}Se_{0.5}$) consisting of mixed chalcogen nets. The thermoelectric power factor of $Bi_2O_2S_{0.5}Se_{0.5}$ is much greater than those of $Bi_2O_2S$ and $Bi_2O_2Se$, suggesting that introducing mixed chalcogen net in $Bi_2O_2Q$ is a possible way of enhancing the thermoelectric property of $Bi_2O_2Q$.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.17 no.10
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• pp.2809-2821
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• 2023

Effective recommendation of similar business groups is a critical factor in obtaining market information for companies. In this study, we propose a novel method for enhancing similar business group recommendation by incorporating derivative criteria and web crawling. We use employment announcements, employment incentives, and corporate vocational training information to derive additional criteria for similar business group selection. Web crawling is employed to collect data related to the derived criteria from 'credit jobs' and 'worknet' sites. We compare the efficiency of different datasets and machine learning methods, including XGBoost, LGBM, Adaboost, Linear Regression, K-NN, and SVM. The proposed model extracts derivatives that reflect the financial and scale characteristics of the company, which are then incorporated into a new set of recommendation criteria. Similar business groups are selected using a Euclidean distance-based model. Our experimental results show that the proposed method improves the accuracy of similar business group recommendation. Overall, this study demonstrates the potential of incorporating derivative criteria and web crawling to enhance similar business group recommendation and obtain market information more efficiently.

• KDI Journal of Economic Policy
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• v.39 no.4
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• pp.25-50
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• 2017

Whereas a large variety of previous studies show mixed results regarding the relationship between public investment and economic outcome, several studies have been conducted on related issues in Korea. The present study deals with the effect of public investment in Korea on economic growth and productivity. Using administrative data, it exploits three different methodologies: the total factor productivity approach, production function approach, and stochastic frontier production function approach. The results of this study show that public investment has a statistically significant effect on economic growth. However, it contributes little to enhance productivity. It is explained that there exists inefficiency of production in the Korean economy. These findings indicate that public investment has played a central role in the direct input factor and not in indirect role in Korea. Thus, it is necessary for public investment policies to concentrate on enhancing the efficiency of the Korean economy.

• Journal of the Korean Society of Clothing and Textiles
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• v.33 no.7
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• pp.1050-1060
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• 2009

This study develops a scale for consumer clothing satisfaction based on Lee et al. 's (2002) five stages of the consumer life cycle (acquisition, possession, consumption, maintenance, and disposal). Data were gathered by surveying college students using convenience sampling, and 419 questionnaires were used in the statistical analysis. In analyzing the data, an exploratory factor analysis and a confirmatory factor analysis using a structural equation modeling were conducted. The proposed scale, which identified various sources of satisfaction and dissatisfaction associated with the 5 consumption cycles of clothing, suggests some guidelines for marketers in enhancing consumer clothing satisfaction across consumption stages. The model test for the scale also identified that consumption satisfaction had the greatest effect on consumer clothing satisfaction showing the strongest loading and squared multiple correlation.