• Journal of the Korean Society of Food Science and Nutrition
• /
• v.43 no.2
• /
• pp.216-223
• /
• 2014

Curcuma longa L. (CL) is a well known traditional medicinal plant that is also used in curries and mustards as a coloring and flavoring agent. However, CL is not usually used as a food source due to its bitter taste. We investigated the immunomodulatory effect of CL fermented by Aspergillus oryzae (FCL) on RAW 264.7 cells. FCL was extracted with cold water (CW), hot water (HW), 20% ethanol (20% EtOH) and 80% ethanol (80% EtOH), after which its effects on phagocytic activity, tumor necrosis factor-alpha (TNF-${\alpha}$), nitric oxide (NO) production, natural killer (NK) cell activity and mRNA expression of LP-BM5 eco were investigated. Phagocytic activity was increased in HW and 20% EtOH when compared to the control. The secretion of nitric oxide (NO) from RAW 264.7 cells did not change significantly relative to the control. However, TNF-${\alpha}$ was significantly increased by the addition of FCL extracts. Moreover, FCL 20% ethanol extract showed a four fold increase in NK cell cytotoxity relative to the control group. Finally, we observed suppressed mRNA expression of LP-BM5 eco in FCL extracts, especially in the 20% ethanol extracts group. These results indicate that the FCL extracts can be used as a functional material due to their effective immunomodulating activities.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.35 no.4
• /
• pp.987-996
• /
• 2015

According to the recent research results of the Ministry of Environment, the indoor air quality of large general hospitals and university hospitals(58 hospitals) exceeded the maintenance standard. On top of such indoor air quality, it is also desperately required to have the environment-friendly building design and also low carbon green design in accordance with the increase of hospital size and enlarged hospital buildings. Especially, the increase of carbon dioxide, heat, garbage, waste energy, exhaust heat from power plants and sewage heat in each medical center brings up lots of problems to the health of hospital patients and customers. Thus this study aims to convergently develop the green environment-friendly architecture design technology concerning the organic relations between each medical building, and technical development which should be introduced to the low carbon green environment-friendly architecture design based on the characteristics of each medical center in large-scale medical complex.

• Journal of the Korean Society of Floral Art and Design
• /
• no.42
• /
• pp.37-62
• /
• 2020

The earth is a natural material that has natural healing power,,as a natural ingredient, it brings environmental friendliness, emotional. In this Research, for one of the methods to expand the benefits as a healing space, Construction of the Earth design and earth construction methods have been actively used for effectiveness of the Earth in the construction of the interior with the oriental medical clinic. By utilizing the concept of biophilic design as a healing environment design, symbolizing nature such as color, light, plants, flowers, and natural materials such as earth and wood was directed as oriental medicine interiors. In addition, the space was divided according to the movement of patients and used different Earth construction method to each of the space for the distinction and differentiation according to the characteristics of each space. At this time, the Earth was constructed with materials and finishing materials that meet the highest grade of HB (Healthy Building), an eco-friendly building material certification grade without additives, so that the interior and medical treatment concept can be done at the same time. By using Earth as the basis of elements in the construction, and the design of healing space, patient the concept of Biophillic as a healing environment design. This may serve as a technical, aesthetic, and cultural basis for constructing a healing space by Earth in the future-oriented alternative, it may lead to necessity of eco-friendly and ecological architecture, and it may be an opportunity to expand the application area of earth in architectural design.

• Tuberculosis and Respiratory Diseases
• /
• v.44 no.1
• /
• pp.136-145
• /
• 1997

Background : Tracheal Gas Insufflation (TGI) is one of the newer ancillary measures in mechanical ventilation employed to enhance carbon dioxide elimination. TGI exerts its effect through reduction of deadspace ventilation, but the factors determining its effect are not well studied yet. Method : The subjects were seven mechanically-ventilated patients ($58.8{\pm}10.6$ yrs) who showed increased physiologic deadspace greater than 60%. After 30 nun of stabilization with 100% oxygen on pressure control ventilation, continuous flow TGI was administered via the insufflation lumen of Hi-Lo Jet Tracheal Tube (Mallincrodt, USA) for 15 min at 3 L/min and 5 L/min each. Results : $PaCO_2$ was decreased ($51.4{\pm}17.6$ at baseline, $49.1{\pm}18.9$ at TGJ 3 L/min $45.0{\pm}14.9$ mm Hg at TGI 5 L/min, p=0.050), and pH was increased ($7.37{\pm}0.12$, $7.38{\pm}0.13$, $7.39{\pm}0.12$, respectively, p=0.037) while mixed expired $CO_2$ ($P_ECO_2$) was not changed significantly from baseline (p=0.336) by TGI. Physiologic deadspace(Vdphy) was decreased ($73.0{\pm}7.9$% at baseline, $69.8{\pm}10.0$% at TGI 3 L/min, and $67.1{\pm}10.1$% at TGI 5 L/min, p=0.015). $AaDO_2$(p=0.147), Vt(p=0.2140), Pmean(p=0.7788) and mean arterial pressure(p=0.4169) were not changed. The correlation between % maximal decrease of Vdphy were r=0.790 with the ratio of baseline Vdana/Vdphy(p=0.035) and r=-0.754 with baseline Vdalv(p=0.050). Conclusion: TGI was effective in reducing $PaCO_2$ and deadspace, and the deadspace-reducing effect was best correlated with baseline anatomic/physiologic deadspace ratio.

• Journal of the Korea Convergence Society
• /
• v.12 no.10
• /
• pp.129-136
• /
• 2021

Radiation shields used in medical institutions mainly use lead to manufacture products and fitments. Although lead has excellent processability and economic efficiency, its use is being reduced due to environmental issues when it is disposed of. In addition, when used for a long time, there is a limit to using it as a shielding film, shielding wall, medical device parts, etc. due to cracking and sagging due to gravity. To solve this problem, copper, tin, etc. are used, but tungsten is mostly used because there is a difficulty in the manufacturing process to control the shielding performance. However, it is difficult to compare with other shielding materials because the characteristics according to the type of tungsten are not well presented. Therefore, in this study, a medical radiation shielding sheet was manufactured in the same process using pure tungsten, tungsten carbide, and tungsten oxide, and the particle composition and shielding performance of the sheet cross-section were compared.As a result of comparison, it was found that the shielding performance was excellent in the order of pure tungsten, tungsten carbide, and tungsten oxide.

• Journal of the Korea Convergence Society
• /
• v.12 no.6
• /
• pp.33-38
• /
• 2021

In order to manufacture a lightweight medical radiation shielding sheet, a new shielding material was studied. We tried to verify the possibility of a shielding material by mixing egg shell powder, which is thrown away as food waste at home, with a polymer material. Existing lightweight materials satisfy eco-friendly conditions, but there are difficulties in the economics of shielding materials due to the cost of the material refining process. This study aims to solve this problem by using egg shells, which are household waste. A 3 mm-thick shielding sheet was fabricated using HDPE, a polymer material, and particle distribution within the cross-section of the shielding sheet was also verified. The shape of the particles was rough and there were voids between the particles, and the average weight per unit area was 1.5 g/cm². The shielding performance was around 20% in the low energy area and 10% in the high energy area, showing the possibility of a low-dose medical radiation shielding body.

• Food Science and Preservation
• /
• v.31 no.1
• /
• pp.1-14
• /
• 2024

The utilization of coatings composed of bio-based materials in the processing and preservation of meat presents an environmentally conscious, secure, cost-effective, and superior method for prolonging the storage life of meat while also preserving its nutritional value. In this study, changes in physical, chemical, and microbiological characteristics of freshly cut beef coated with distilled water (control) and keratin-starch composites (K-S) functionalized with 0.0-, 0.2-, 0.6-, and 1.0-mL avocado peel polyphenolic-rich extract (APPPE) kept at 4℃ for 12 days were evaluated periodically at 3-day interval using standard techniques. Keratin was extracted from waste feathers, while starch was obtained from ginger rhizomes. Following a 12-day storage period, beef coated with APPPE-enriched K-S composites exhibited a significant (p<0.05) improvement in shelf life by minimizing deteriorative changes in pH and color (as determined by metmyoglobin level) in addition to inhibiting oxidative changes in lipids (as determined by TBARS level) and proteins (protein carbonyl level) in comparison to control and K-S composite without APPPE. Furthermore, microbial growth was significantly (p<0.05) suppressed in meat coated with K-S composite functionalized with APE at 0.6 and 1.0 mL compared to the control. The study suggested that APPPE-enriched K-S composite could offer an eco-friendly and safe food preservation technique for fresh meat.

• Journal of the Korea Institute of Military Science and Technology
• /
• v.16 no.2
• /
• pp.218-224
• /
• 2013

Organophosphorus compounds are irreversible inhibitors of cholinesterase enzyme. Exposure causes a progression of toxic signs, including hypersecretion, tremor, convulsion, respiratory distress, epileptiform seizure, brain injuries and death. To protect brain injuries, administration of diazepam as a neuroprotectant is now considered essential for severely exposed nerve agent casualties. However, studies have shown diazepam to provide less than total protection against the neuropathological consequences of nerve agent exposure. In this context, extensive studies have been carried out to find out effective alternative drugs to protect brain from epileptiform seizures induced by organophosphate compounds intoxication. It has been reported that a combination of carbamate and anticholinergic or antiglutamatergic can be a very effective medical countermeasure in dealing with the threat of organophosphorous poisoning. In this study, experimental animals including rats and guinea pigs were implanted with microelectrodes on their brain sculls, and treated with various centrally acting drugs such as physostigmine and procyclidine prior to soman challenge, and then its electroencephalography(ECoG) was monitored to see anticonvulsant effects of the drugs. It was found that seizure activities in ECoG were not always in proportion to clinical signs induced by soman intoxication, and that combinative pretreatment with physostigmine plus procyclidine effectively stopped the seizures induced by organophosphorous poisoning.

• Clean Technology
• /
• v.17 no.1
• /
• pp.25-30
• /
• 2011

This study presents a fabrication method of cell-chip using aqueous solution based surface modification. The applications of cell-chip have potential for fundamental study of genetics, cell biology as well as cancer diagnostics and treatment. Conventional methods for fabrication of cell-chip have been limited in economic loss and environmental pollution because of the use of harsh organic solvent, complex process of silicon technology, and expensive equipment. In order to fabricate cell chip, we have proposed simple and eco-friendly process combined polyelectrolyte multilayer coating with microcontact printing. For the proof of concept, the cell chip can be applied to analyze the different expression of cell surface glycans and derivatives between cancer and normal cells. Our proposed method is useful technique for the application of novel cancer diagnostics and basic medical engineering.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.33 no.11
• /
• pp.1696-1706
• /
• 2009

Nonwoven fabrics have been widely used in various fields that include household, industrial, agricultural, medical goods, especially in the automobile industry. In this study, eco-friendly fiber materials were developed and investigated as a substitute material for polyester fibers in nonwovens. To make plant fiber bundles, stems of Indian mallow (IM), and Kuzu vine (KV) were retted; in addition, the non-cellulose component was partially removed. Plant fiber bundles and polyester fibers (P) were blended and needle punched to produce nonwovens. Five kinds of nonwovens were manufactured: P100 (Polyester 100%), IM10 (IM 10% and Polyester 90%), IM20 (IM 20% and Polyester 80%), KV10 (KV 10% and Polyester 90%), and KV20 (KV 20% and Polyester 80%). The color values, surface appearance, tensile strength, elongation, tear strength, abrasion strength, flexstiffness, moisture regain, water or oil absorbency, and static electricity of manufactured nonwovens are investigated. As the blended ratios of IM or KV increased, the brightness of nonwovens decreased compared to that of polyester 100%. Tensile strength, tear strength, abrasion strength, and flexstiffness of IM10 as well as KV10 were higher than those of P100, IM20, and KV20, resulting from the influence of the structure and properties of nonwoven fibers. Moisture regain and water or oil absorbency increased, while static electricity decreased in proportion to the amount of plant fibers. IM or KV and polyester blended nonwovens showed improved properties over P100 that could be substituted for P100 as a novel material for textiles.