• Title/Summary/Keyword: eIF4E

Search Result 1,268, Processing Time 0.039 seconds

STRONG P-CLEANNESS OF TRIVIAL MORITA CONTEXTS

  • Calci, Mete B.;Halicioglu, Sait;Harmanci, Abdullah
    • Communications of the Korean Mathematical Society
    • /
    • v.34 no.4
    • /
    • pp.1069-1078
    • /
    • 2019
  • Let R be a ring with identity and P(R) denote the prime radical of R. An element r of a ring R is called strongly P-clean, if there exists an idempotent e such that $r-e=p{\in}P$(R) with ep = pe. In this paper, we determine necessary and sufficient conditions for an element of a trivial Morita context to be strongly P-clean.

Effect of Chamomile German Oil Application of IgG1 and IgE 1 to Atopic Dermatitis in NC/Nga Mice Model (Chamomile German 오일도포가 아토피성 피부염을 가진 NC/Nga 생쥐모델의 혈청 IgE와 IgG1양 변동에 미치는 영향)

  • Shin, Gil-Ran;Kim, Yang-Weon
    • Korean Journal of Human Ecology
    • /
    • v.18 no.2
    • /
    • pp.501-507
    • /
    • 2009
  • Atopic dermatitis is one of the most common skin disease in children and a characteristic chronically recurrent form of dermatitis with a hereditary tendency, affecting infants and may extend to the childhood or th the adult age. Environmental factors, stress, and foodstuffs such as milk, egg may cause atopic dermatitis. Nc/Nga mice were used as an animal model for human atopic dermatitis. The divided by 4group such as normal group, BMAC group, FK506 group, MR group for this study raised in conventional conditions. To investigate effect of Chamomile German on atopic dermatitis in NC/Nga mice, the serum IgE and IgG1 level were measured while the severity degree of the skin lesion was examined by the naked eyes of two volunteers who were unaware of the treatment status. The results were the followings. 1. The score on the severity degree of skin dermatitis in FK 506 and MR group was lower than that in control group. 2. The serum IgE level in control group was higher 25% than that in normal group. 3. The serum level of IgE in FK506 and MR group compares to control group was decreased. 4. The serum IgG1 level was decreased more than 3.5 times in FK506 compared to control group while MR group had significantly less the serum IgG1 than control group. From the above results, treatment of Chamomile German oil had the effect on atopic dermatitis in NC/Nga mice. If scientific researches on aroma oil are performed in various way, aroma oil will be used to cure skin dermatitis as a alternative therapy in the future.

Development of Enterococcus faecalis Strains Resistant to Rifampicin and Ofloxacin (리팜피신과 오플로삭신에 내성인 Enterococcus faecalis 균주의 개발)

  • Lee, Soo-Hwa;Kim, Sook-Kyung;Chung, Young-Ja;Shim, Mi-Ja;Kim, Byong-Kak;Choi, Eung-Chil
    • YAKHAK HOEJI
    • /
    • v.40 no.3
    • /
    • pp.351-356
    • /
    • 1996
  • The preparation of Enterococcus faecalis RSI is used as a therapeutics for human intestinal disorders. However, the microbe in this preparation is usually very sensitive to rifampicin and fluoroquinolones. If this preparation is taken with rifampicin or fluoroquinolones, its therapeutic effect can not be expected. E. faecalis RFR11, containing resistance to rifampicin was obtained by MNNG mutation method. Serial passage of E. faecalis RFR11 produced E. feacalis OFR16 on agar with 2-fold minimal inhibitory concentration of ofloxacin produced. E. feacalis OFR16 was resistant to fluoroquinolones up to 8-256 fold higher than that for the original strain. E. faecalis OFR16 also exhibited identical characteristics with the parent strain when they were tested for lactic acid formation and growth inhibition of E. coli MB4-5737 and Shigella sonnei MB4-10411. From in vitro test, it was identified that rifampicin and ofloxacin is not inactivated by certain factors of E. faecalis OFR16. Conclusively. E. faecalis OFR16, rifampicin and fluoroquinolones resistant mutant, is an efficient strain that has insensitivity against rifampicin and fluoroquinolones and original biochemical characteristics of the parent strain.

  • PDF

A Strong Designated Verifiable DL Based Signcryption Scheme

  • Mohanty, Sujata;Majhi, Banshidhar
    • Journal of Information Processing Systems
    • /
    • v.8 no.4
    • /
    • pp.567-574
    • /
    • 2012
  • This paper presents a strong designated verifiable signcryption scheme, in which a message is signcrypted by a signcryptor and only a specific receiver, who called a "designated verifier", verifies it using his own secret key. The scheme is secure, as an adversary can not verify the signature even if the secret key of the signer is compromised or leaked. The security of the proposed scheme lies in the complexity of solving two computationally hard problems, namely, the Discrete Logarithm Problem (DLP) and the Integer Factorization Problem (IFP). The security analysis of the scheme has been done and it is proved that, the proposed scheme can withstand an adaptive chosen ciphertext attack. This scheme can be very useful in organizations where there is a need to send confidential documents to a specific recipient. This scheme can also be applicable to real life scenarios, such as, e-commerce applications, e-banking and e-voting.

BOUNDED MOVEMENT OF GROUP ACTIONS

  • Kim, Pan-Soo
    • Communications of Mathematical Education
    • /
    • v.5
    • /
    • pp.523-523
    • /
    • 1997
  • Suppose that G is a group of permutations of a set ${\Omega}$. For a finite subset ${\gamma}$of${\Omega}$, the movement of ${\gamma}$ under the action of G is defined as move(${\gamma}$):=$max\limits_{g{\epsilon}G}|{\Gamma}^{g}{\backslash}{\Gamma}|$, and ${\gamma}$ will be said to have restricted movement if move(${\gamma}$)<|${\gamma}$|. Moreover if, for an infinite subset ${\gamma}$of${\Omega}$, the sets|{\Gamma}^{g}{\backslash}{\Gamma}| are finite and bounded as g runs over all elements of G, then we may define move(${\gamma}$)in the same way as for finite subsets. If move(${\gamma}$)${\leq}$m for all ${\gamma}$${\subseteq}$${\Omega}$, then G is said to have bounded movement and the movement of G move(G) is defined as the maximum of move(${\gamma}$) over all subsets ${\gamma}$ of ${\Omega}$. Having bounded movement is a very strong restriction on a group, but it is natural to ask just which permutation groups have bounded movement m. If move(G)=m then clearly we may assume that G has no fixed points is${\Omega}$, and with this assumption it was shown in [4, Theorem 1]that the number t of G=orbits is at most 2m-1, each G-orbit has length at most 3m, and moreover|${\Omega}$|${\leq}$3m+t-1${\leq}$5m-2. Moreover it has recently been shown by P. S. Kim, J. R. Cho and C. E. Praeger in [1] that essentially the only examples with as many as 2m-1 orbits are elementary abelian 2-groups, and by A. Gardiner, A. Mann and C. E. Praeger in [2,3]that essentially the only transitive examples in a set of maximal size, namely 3m, are groups of exponent 3. (The only exceptions to these general statements occur for small values of m and are known explicitly.) Motivated by these results, we would decide what role if any is played by primes other that 2 and 3 for describing the structure of groups of bounded movement.

  • PDF

Delay time Analysis of Asynchronous RIT Mode MAC in Wi-SUN (Wi-SUN에서 비동기 RIT모드 MAC의 지연시간 분석)

  • Dongwon Kim;Mi-Hee Yoon
    • The Journal of the Institute of Internet, Broadcasting and Communication
    • /
    • v.24 no.2
    • /
    • pp.65-70
    • /
    • 2024
  • In recent years, research on smart factory wireless mobile communication technology that wirelessly remotely controls utilities is being actively conducted. The Wi-SUN (Wireless Smart Utility Network) Alliance proposed a Wi-SUN protocol structure suitable for building a platform such as a smart factory as a new wireless communication standardization standard based on EEE802.15.4g/e. It analyzes the performance of the IEEE802.15.4e Receiver Initiated Transmission(RIT) Mode Media Access Control (MAC) in terms of throughput and latency, and looks at considerations for efficient operation. RIT mode shows that as the check interval becomes longer, delay time and throughput decrease. It was shown that as the traffic load increases, if the RIT check interval is shortened, the delay time can be shortened and throughput can be increased. RIT mode has the advantage of low power consumption and has neutral characteristics between IEEE802.15.4 and CSL mode in terms of delay time and throughput.

MINIMAL WALLMAN COVERS OF TYCHONOFF SPACES

  • Kim, Chang-Il
    • Journal of the Korean Mathematical Society
    • /
    • v.34 no.4
    • /
    • pp.1009-1018
    • /
    • 1997
  • Observing that for any $\beta_c$-Wallman functor $A$ and any Tychonoff space X, there is a cover $(C_1(A(X), X), c_1)$ of X such that X is $A$-disconnected if and only if $c_1 : C_1(A(X), X) \longrightarrow X$ is a homeomorphism, we show that every Tychonoff space has the minimal $A$-disconnected cover. We also show that if X is weakly Lindelof or locally compact zero-dimensional space, then the minimal G-disconnected (equivalently, cloz)-cover is given by the space $C_1(A(X), X)$ which is a dense subspace of $E_cc(\betaX)$.

  • PDF

An Interferon Resistance Induced by the Interaction between HCV NS5B and Host p48 (C형 간염 바이러스 NS5B 단백질과 숙주의 p48 단백질의 상호작용에 의한 인터페론 저항성의 유도)

  • Park, So-Yeon;Lee, Jong-Ho;Myung, Hee-Joon
    • Microbiology and Biotechnology Letters
    • /
    • v.36 no.4
    • /
    • pp.353-359
    • /
    • 2008
  • Hepatitis C virus (HCV) is known as the causative agent of blood transmitted hepatitis. Two viral proteins, E2 and NS5A, are known to exert interferon resistance of HCV via PKR pathway. Here, we report a third protein, the RNA-dependent RNA polymerase (NS5B) of HCV, induced interferon resistance inhibiting p56 pathway. p56 was shown to interact with p48 subunit of eukaryotic initiation factor 3 (eIF3). This interaction inhibited formation of ternary complex in translation initiation. Using dual reporter assay system, we observed that the translation decreased when interferon alpha was added to the culture. But, in the presence of HCV NS5B, the translation partly recovered. NS5B and p48 subunit of eIF3 were shown to interact. This interaction seems to inhibit the interaction between p48 and p56. This is the first report that a virus exerts interferon resistance via p56 pathway.

On the Likelihood of Peace and War on the Korean Peninsula: A Causal Loop Analysis

  • Kim, Gang-Hoon
    • Korean System Dynamics Review
    • /
    • v.10 no.4
    • /
    • pp.5-25
    • /
    • 2009
  • Since the end of the 1950-1953 Korean War, many scholars and policymakers have expressed concern about the possibility of another conflict on the peninsula. In certain respects, the post-1953 North-South Korea relationship resembles the Cold War that existed between the United States and the Soviet Union, 1945-1990. Although a "hot" never occurred, peace was never guaranteed. By looking at international theories (i.e., realism and liberal theory) and by utilizing casual-loop diagram analysis, the main purpose of this research is to explore on the likelihood of peace and war on the Korean peninsula. First, several factors (e.g., economic stagnation of North Korea, unstable political systems, and so on) emphasized by realism perspectives are significantly related to the likelihood of conflict between North and South Korea. Conversely, several determinants (e.g., economic assistance to North Korea, inter-dialogue between two Koreas, cultural and social exchange, and so on) emphasized by liberal approaches are significantly related to likelihood of peace on the Korean peninsula. Given the two different interpretations about the likelihood of conflict or peace, it can be argued that a second military action might occur on the Korean peninsula if realism theories are true. However, if practical factors exist on the Korean peninsula, the two Korean can optimistically expect a peaceful reunification in the future, without interference from other countries.

  • PDF