• 한국환경과학회지
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• 제28권7호
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• pp.639-643
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• 2019

We aimed to evaluate antithrombotic efficacy of Protaetia brevitarsis extract during 21 days. Rats (SPF rat, weight 240~260 g) were divided into 16 groups (5 rats per group), they were: control group and Protaetia brevitarsis extract groups with dose of 0.1, 0.5, 1, 2.5, 5, 10, 25, 50, 75, 100, 200, 250, 500, 750, 1,000 mg/kg kg of body weight. Thromboplastin time (PT) and activated partial thromboplastin time (aPPT) as antithrombotic efficacy were tested in this animal experiment (at 7, 14 and 21 days). Overall, the admistration dose of Protaetia brevitarsis extract over 50 mg/kg at 7, 14 and 21 days for PT and over 25 mg/kg at 7, 14 and 21 days for aPPT tented to be longer than that of other groups. In addition, the optimal admistration doses of Protaetia brevitarsis extract to improves antithrombotic efficacy were 75, 100, 200 and 250 mg/kg at 7, 14 and 21 days for PT (p<0.05) and 50 and 100 mg/kg at 7 days, 75 mg/kg at 14 days, or 50, 100, 200 and 250 mg/kg at 21 days for aPPT (p<0.05). It can be concluded that Protaetia brevitarsis extract at optimal levels have antithrombotic efficacy.

• 디지털융복합연구
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• 제17권6호
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• pp.365-371
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• 2019

본 연구는 예술적 장르인 르네마그리트의 초현실주의 작품 레슬러의 무덤의 소재인 장미를 모티브로 활용하여 VR콘텐츠를 제작하였다. 현재 시장은 VR콘텐츠의 대중화로써 게임, 체험형 전시로 활성화 되고 있다. VR콘텐츠의 문제점은 관람자에게 게임, 단순 체험형 전시보다 예술적 장르인 콘텐츠 개발이 필요하다. 데페이즈망 기법을 공간의 변조(왜곡), 모순된 이미지의 결합(중첩), 물체의 변형과 변화(스케일) 3가지 키워드로 분류하고 프랙탈 구조의 왜곡, 중첩, 스케일의 3D 착시 패턴을 데페이즈망에 대입하였고, 이미지스케일 도구를 활용하여 장미를 대입하였다. 결론으로 이미지 스케일의 왜곡(공간의 변조)은 Dynamic-curve, Texture-soft 영역에 연결하였고, 중첩(모순된 이미지의 결합)은 Big-size, Irregular-depth영역, 스케일(물체의 변형과 변화)은 big-size, Irregular-space영역의 포지션에 연결하였다. 타임라인별 방안에 식물과 장미패턴을 제작하여 Overlap, Scale, Distortion, Overlap, Distortion, Scale 순으로 진행이 되었고, 착시효과의 다양성을 활용하여 문제점을 보완하였다. 본 연구를 바탕으로 인지적, 물리적, 기능적, 감각적 어포던스 오감을 활용한 완성도 높은 예술적 VR 영상 콘텐츠를 제작할수 있을것으로 기대한다.

• 융합정보논문지
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• 제9권3호
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• pp.44-55
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• 2019

본 연구의 목적은 남자 대학생들의 스포츠토토 도박을 통해 겪게 되는 경험과 그들이 당면하고 있는 문제를 파악하여 남자 대학생 도박중독의 예방 및 회복 프로그램에 기초자료를 제공하고자 시도하였다. 본연구의 참여자들은 8명의 남자 대학생으로 심층 인터뷰 한 자료를 Colaizzi의 현상학적 연구방법에 따라 분석하였다. 연구결과 경험의 범주는 4개로 바다로 달려가는 바람처럼, 회한으로 흐르는 눈물, 수면 아래로 잠긴 삶, 꿈을 꾸는 날엔 으로 도출되었다. 본 연구를 통해 스포츠토토는 접근성이 용이하고 흥미 유발적인 요소가 많지만, 일반 도박자들과 마찬가지로 자기 통제력을 상실한 채 중독에 빠질 위험이 크다는 것이 드러났다. 그렇지만 도박 기간이 짧은 대학생이 경제적 자금 조달의 한계점으로 현실을 자각할 경우 도박중독 위험으로부터 비교적 빠르게 격리될 수 있다고 본다. 따라서 스포츠를 좋아하는 대학생들을 위한 도박 예방교육과 상담이 필요할 것으로 생각된다.

• PNF and Movement
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• 제16권3호
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• pp.365-376
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• 2018

Purpose: This study investigates research trends in the Proprioceptive Neuromuscular Facilitation (PNF) and Movement journal. Methods: This study analyzes the frequency of keywords and their coincidences with medical subject headings (MeSH) over 15 years in 315 papers from volume 1, issue 1 to volume 15, issue 3 of a journal published by the Korean Proprioceptive Neuromuscular Facilitation Association. The research types and levels are also analyzed, and the journals are classified by subject, diagnosis, application of PNF, and technique used when PNF is applied. All of the variables are classified in five-year units and their trends are examined. Results: A total of 315 papers were published in 40 issues, and 1190 keywords were used over 15 years. The most frequently used keyword was "PNF." For the keywords that coincided with the MeSH, there were 235 (19.74%) complete coincidence words, 167 (14.03%) incomplete coincidence words, and 788 (66.21%) complete incoincidence words. Thus, the number of complete incoincidence words was the largest. For research types, there were 196 (61.90%) experimental studies, which was the most studied research type. For research levels, there were 155 (49.21%) Level 3 studies (non-randomized trial), which was the research level with the largest number of papers. Normal people were the most common subjects (121 cases, 38.41%), and the number of papers that did not use PNF was 187 (59.37%), which was larger than those that used PNF. The most frequently used combination technique was isotonics when PNF was used. Conclusion: Basic data on PNF-related research was obtained by analyzing papers published over the past 15 years. This information can be used to suggest future directions for PNF research.

• 비교문화연구
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• 제25권
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• pp.363-389
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• 2011

Modern Chinese Literature, the so-called 'feminist' is a very modern and the traditional criticism and took an important position in the double action. Because a woman's freedom from the bondage of traditional ethics of restoring the social status equal to men but to women does not give, that compared to men and women just the dimension of the problem of isolation is not just. It is dominated by yugajeok worldview by streamlining the whole Chinese society to build a modern society and the country was a critical task. However, multi-cultural life of Lin, Hui-yin and Ling, Shu-hua in the history of the world's attention to the shrine was worried attention to soils, rather than East-West dualism law by taking a mixture of both women in modern Chinese literature and Western literature from the center of efforts to overcome the traditional point hayeotdaneun feminist literature that may be different. Lin, Hui-yin and Ling, Shu-hua to overcome the Western-oriented culture really the true dream of China's globalization and localization could be regarded. She naesewotdeon the banner of feminist literature in the traditional 'anti feudal', 'free personality' silcheondoen under such slogans as well as women's liberation from traditional, male-oriented perspective away from the women's unique experiences and new understanding of the value of the superiority the concept of a woman, and was to create. In particular, the femininity of these women who traditionally associated with women and the unique culture - the creation of a new consciousness, a re-evaluation of traditional feminine skills and talents was to try to.

• Journal of Gynecologic Oncology
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• 제29권6호
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• pp.93.1-93.11
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• 2018

The introduction of checkpoint inhibitors revolutionized immuno-oncology. The efficacy of traditional immunotherapeutics, like vaccines and immunostimulants was very limited due to persistent immune-escape strategies of cancer cells. Checkpoint inhibitors target these escape mechanisms and re-direct the immune system to anti-tumor toxicity. Phenomenal results have been reported in entities like melanoma, where no other therapy was able to demonstrate survival benefit, before the introduction of immunotherapeutics. The first experience in ovarian cancer (OC) was reported for nivolumab, a fully human anti-programmed cell death protein 1 (PD1) antibody, in 2015. While the data are extraordinary for a mono-immunotherapeutic agent and very promising, they do not match up to the revolutionary results in entities like melanoma. The key to exceptional treatment response in OC, could be the identification of the most immunogenic patients. We hypothyse that BRCA mutation could be a predictor of improved response in OC. The underlying DNA-repair-deficiancy should result in increased immunogenicity because of higher mutational load and more neoantigen presentation. This hypothesis was not tested to date and should be subject to future trials. The present article gives an overview of the immunologic background of checkpoint inhibition (CI). It presents current data on nivolumab and other checkpoint-inhibitors in solid tumors and OC specifically and depicts important topics in the management of this novel substance group, such as side effect control, diagnostic PD-1/programmed cell death-ligand 1 (PD-L1) expression assessment and management of pseudoprogression.

• Journal of Information Technology Applications and Management
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• 제25권3호
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• pp.17-28
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• 2018

In this paper, an activity-oriented usability model is proposed. The usability model contains two types of characteristics: special-type characteristics of usability and sub-characteristics of usability. Workability, study-ability, and playability are, but do not exhaust, examples of special-type characteristic of usability. They correspond to working, studying, and playing using the software product, respectively. They represent the goal of using and can overlap each other. They are usability too by themselves. Navigate-ability, data-prepare-ability, data-input-ability, response-wait-ability, output-examine-ability, and output-utilize-ability are typical examples of sub-characteristics of usability. They correspond to navigating, preparing data, inputting data, waiting response, examining output, and utilizing the output data, respectively. They are not usability by themselves. They constitute usability together as a group. Assessing is the fundamental and indispensable aspect of quality. Without assessing, the concept of quality has little practical value. Satisfaction, effectiveness, and efficiency are the most typical sub-characteristics of usability in existing quality models, which correspond to the evaluation criteria of usability. In the activity-oriented usability model, however, only the user's satisfaction is included: Satisfaction is regarded as the operational definition of usability in the user's view. As the result, usability can be interpreted as the 'goodness for using, which is evaluated by the user. 'Three fundamental principles regarding software quality models are proposed too in this paper: Principles of Parsimony, Cohesiveness, and Inheritance. Discussions illustrate well that typical existing usability models violate these basic principles. Many authors have tried to define general usability models which can be applied to most kinds of software. The dream of the general and universal usability model, however, may be an illusion. The activity-oriented usability model is expected to serve as a prototype from which specialized usability models can be derived.

• 영미문화
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• 제14권1호
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• pp.219-239
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• 2014

Arjun Appadurai contends that "the new global cultural economy has to be seen as a complex, overlapping, disjunctive order that cannot any longer be understood in terms of existing center-periphery models" (32); though discerning and perhaps becoming more and more apt, Appadurai's observation of the breakdown of the "center-periphery" binary appears as mere "academic jargon" in the lives of new immigrants, tackling the murky waters of identity politics in the transcultural technoscape of modern America in Kunzru's Transmission. Kunzru's antihero is Arjun Mehta, a software technician, who comes to America with high hopes of realizing the "American Dream." To a certain extent, Arjun himself is culpable of resurrecting the "center" as he prioritizes America and its values over all else. Despite his best efforts, Arjun cannot prevail in the perilous politics of exclusion/inclusion, and is relegated into a "high-tech coolie," exploited for his technological savvy. Even as the "center-periphery" binary stays intact in the production of an (Asian) American identity, it becomes undone in the hands of this "would-be" American; ultimately denied inclusion into America, Arjun unleashes a destructive virus that has major global consequences. In a sense, the boundary that separates the center and the periphery comes down as both collectively become victims to Arjun's retributive malfeasance. Arjun seems to rely on the "American" promise that old allegiances (to a national identity) are now defunct and new ones can be easily forged; as Kunzru's Transmission demonstrates with the tragic story of Arjun, the complex politics of identity production in America does not necessarily deliver on this promise. This essay hence aims to examine the politics of (national) belonging in the age of transnationalism.

• 한국환경과학회지
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• 제30권2호
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• pp.185-189
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• 2021

This study was conducted to determine and to standardize the time of emergence of Protaetia brevitarsis adults, through four breeding experiments, including one which selected the dominant individuals of Protaetia brevitarsis. The breeding experiments were divided into two groups with hibernating and non-hibernating Protaetia brevitarsis by placing 100, 150, 200, 250 and 300 Protaetia brevitarsis in each breeding box (50 cm × 35 cm × 15 cm) filled with 12 L of fermented sawdust. Breeding tests were with four replicates each for 3 months. The test period was classified into four stages: Exp. 1 (Sep 1, 2019 to Nov 30, 2019), Exp. 2 (Dec 1, 2019 to Feb 29, 2020), Exp. 3 (Mar 1, 2019 to May 31, 2020) and Exp. 4 (Jun 1, 2020 to Aug 31, 2020). The survey items included average dead number, average emergence number, average mortality, and average emergence rate. In Exp. 1 and 2, the changes in Protaetia brevitarsis adults were similar. In Tables 1 and 2, the allegorical changes of adult white-spotted flowers were similar. In addition, the average dead number, average emergence number, average mortality, and average emergence rate showed better results in the hibernation state than in both Exp. 1 and 2. Exp. 3 and 4 showed a pattern of change different from the results of Exp. 1 and 2 and these characteristics were superior in the hibernation states compared to the non-hibernation states. In conclusion, this result was found to be most appropriate as a standardization of the emergence time of 200 Protaetia brevitarsis treatments through four breeding experiments in the hibernating state.

• 디지털융복합연구
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• 제20권4호
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• pp.419-431
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• 2022

본 연구는 신규간호사를 대상으로 감성지능 향상프로그램을 적용 후 감성지능 및 직무스트레스에 미치는 효과를 파악하고자 시도 되었다. 혼합연구설계이며 연구대상자는 신규간호사 29명(실험군 15명, 대조군 14명)을 대상으로 감성지능 향상프로그램을 주 1회 총 8주(20시간) 실시하였다. 양적연구는 SPSS/WIN 18.0을 이용하여 Chi-square, Fisher's exact test, t-test, repeated measure ANOVA로 분석하였고 질적연구는 내용분석을 하였다. 실험군의 감성지능과 직무스트레스가 대조군에 비해 통계적으로 유의한 효과가 없었다. 질적내용 분석결과 감성지능이 향상됨 임파워링 됨, 스트레스가 줄어듬, 나에서 우리로 변함, 미래의 나를 꿈꾸게 됨으로 나타났다. 다양한 시기의 간호사를 대상으로 감성지능 향상프로그램을 적용하고 그 효과를 검증하는 연구를 제언한다.