• Title/Summary/Keyword: division of fraction

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Inhibition of Topoisomerase-mediated DNA Cleavage by Lycoperdon perlatum (말불버섯 추출물의 Topoisomerase 저해 효과)

  • Park, Mi-Jung;Cho, Kang-Jin;Kim, Jung-Bong;Kim, Dong-Hern;Kim, Yang-Sub;Seok, Soon-Ja;Kim, Sun-Yeou;Hwang, Young-Soo
    • Korean Journal of Food Science and Technology
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    • v.29 no.5
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    • pp.1057-1062
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    • 1997
  • In the course of searching for anticancer agents from 32 mushrooms, it was found that methanol extract of Lycoperdon perlatum showed inhibitory effect on topoisomerase II-mediated DNA cleavage. This active methanol extract was sequentially fractionated with hexane, chloroform, n-buthanol and water. Among the solvent-fractionated extracts, $1\;{\mu}g/mL$ hexane fraction of L. perlatum inhibited on topoisomerase II-mediated DNA cleavage. The effect of hexane fraction of L. perlatum was dose- and reaction time-dependent. The hexane fraction of L. perlatum was found to have inhibitory activity on relaxation assay of DNA topoisomerase I. The hexane fraction of cultured L. perlatum, however, had no inhibitory effect on either type of topoisomerase.

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Fraction and Mobility of Heavy Metals in the abandoned closed mine near Okdong stream sediments

  • Kim, Hee-Joung;Yang, Jae;Lee, Jai-Young;Jun, Sang-Ho
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2003.09a
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    • pp.56-63
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    • 2003
  • Fractional composition and mobility of sediments some heavy metals in Okdong stream are investigated. The fractional scheme for sediment heavy metal was made for five chemically defined heavy metal forms as adsorbed fraction, carbonate fraction, reducible fraction, organic fraction, and residual fraction (Tessier et at., 1979). The most abundant fraction of the sediment heavy metal is reducible and secondly abundant organic fraction. Adsorbed fraction is minor part of the total heavy metals. Mobilization of sediment heavy metals in stream Okdong is occur 19.8∼56.7% of total cadmium concentrate. The most abundant fraction of the sediment metal is organic fraction in Cu, Pb metals investigated. Labile fraction of sediment metals are 0.5%∼48.5% of total Zn, 2.6%∼48.1% of total Pb, 0.2∼36.9% of total Cu respectively, Most of labile fraction consists of reducible fraction for Cd, Zn, adsorbed fraction for Pb, reducible fraction for Cu, adsorbed fraction for Ni. The Mobilization of Zn and Cu is most likely to occur when oxygen depletes and that of Pb and Ni occurs when physical impact, oxygen depletion and pH reduction.

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An Analysis on the Students' Understanding in Concept and Operations of Decimal Fraction (초등학생들의 소수 개념과 그 연산에 대한 이해도 분석)

  • Moon, Beomshik;Lee, DaeHyun
    • Journal of Elementary Mathematics Education in Korea
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    • v.18 no.2
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    • pp.237-255
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    • 2014
  • The purpose of this study is to investigate elementary school students' understanding the concept and operations of decimal fraction. The survey research was performed for this study. This survey was done by selecting 156 students. Questionnaire were made in five areas with reference to the 2007 revised mathematics curriculum. Five areas were the concept of decimal fraction, the addition, the subtraction, the multiplication and the division of decimal fraction. The results of such analysis are as follow: The analyzed result of understanding about concepts and operation of decimal fraction showed a high rate of correct answer, more than 85%. Students thought that multiplication and division of decimal fraction is more difficult than addition, subtraction, concept of decimal fraction. As the learning about concepts and operation of decimal fraction progress, the learning gap is bigger. Effort to reduce the learning deficits are needed in the lower grades. Mathematics is the study of the hierarchical. Learning deficits in low-level interfere with the learning in next-level. Therefore systematic supplementary guidance for a natural number and decimal fraction in low-level is needed. And understanding concepts and principles of calculations should be taught first.

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An Analysis on the Repeated Error Patterns in Division of Fraction by Elementary Students (초등학생들이 분수의 나눗셈에서 보이는 반복적 오류 분석)

  • Kim, Kyung-Mi;Kang, Wan
    • Education of Primary School Mathematics
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    • v.11 no.1
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    • pp.1-19
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    • 2008
  • This study analyzed the repeated error patterns in division of fraction by elementary students through observation of their test papers. The questions for this study were following. First, what is the most changable thing among the repeated error patterns appeared in division of fraction by elementary students? Second, what is the most frequent error patterns in division of fraction by elementary students? First of all, the ratios of incorrect answers in division of fraction by general students were researched. This research was the only one time. The purpose was to know what kind of compositions in the problems were appeared more errors. Total 554 6th grade students(300 boys and 254 girls) from 6 elementary schools in Seoul are participated in this research. On the basis of this, the study for analysis began in earnest. 5 tests made progress for about 4 months. Total 181 6th grade students(92 boys and 89 girls) from S elementary school in Seoul were participated in this. After each test, to confirm the errors and to classify them were done. Then the repeated error patterns were arranged into 4 types: alpha, beta, gamma and delta type. Consequently, conclusions can be derived as follows. First, most students modify their errors as time goes by even though they make errors about already learned contents. Second, most students who appeared errors make them continually caused a reciprocal of natural number in the divisor when they calculate computations about '(fraction) $\div$ (natural number)'. Third, most students recognize that the divisor have to change the reciprocal when they calculate division of fraction through they modify their errors repeatedly.

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A Study on the Fraction as Quotient and Equal Sharing Strategies in Elementary Mathematics (몫으로서의 분수와 분배전략)

  • Lee, Hosoo;Choi, Keunbae
    • East Asian mathematical journal
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    • v.38 no.4
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    • pp.379-396
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    • 2022
  • In this paper, we investigate distribution strategies in the Egyptian fraction, and through this, we examine the distribution strategies of (fraction)÷(fraction) and then provide some educational implications. The (natural number)÷(natural number) of the sharing situation has the meaning of 'share' per unit, which can be seen as a situation where the unit ratio is determined. These concepts can also naturally be extended to the case of (fraction)÷(fraction) by some problem posing situations. That is to say, the case of (fraction)÷(fraction) can be deduced the case (natural number)÷(natural number) by the re-statement of the problem.

Antifungal Activity of the Quercus Mongolica Extracts Against Botrytis cinerea (신갈나무로부터 유래된 추출물의 Botrytis cinerea 균주에 대한 항균활성)

  • Yeo, Hee Dong;Lee, Hyung Chul;Lim, Bu Kug;Kim, Hee Kyu;Choi, Myung Suk;Yang, Jae-Kyung
    • Journal of the Korean Wood Science and Technology
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    • v.36 no.1
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    • pp.88-101
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    • 2008
  • The aim of this study was to attempt the efficacy of antifungal activity of the wood extracts against Botrytis grey mold. Wood chip derived from Quercus mongolica was obtain from steam explosion process and extracted by hot water and methanol and ethanol. The conidial germination was maximum growth with the application temperature for 20 and $25^{\circ}C$. In pH test, we observed the maximum growth in pH 5.0 and 7.0. Antifungal activity was the best in the hot water extractives against Botrytis cinerea. The separation of the antifungal substances was performed using a silica-gel column (n-hexane : chloroform : ethyl acetate : formic acid = 12 : 17 : 8 : 0.2, v/v/v/v), TLC and UV-Spectrophotometer, and isolated 6 fraction group. The result of antifungal activity in 6 fraction group, fraction group I and fraction group II were the highest antifungal activity against grey mold with the present study. Three peaks in fraction group I and II were detected by HPLC and this compounds were suppose to effective of antifungal activity.

Evaluation of Antioxidant Activities and Active Compounds Separated from Water Soluble Extracts of Korean Black Pine Barks

  • Shen, Chang-Zhe;Jun, Hong-Young;Choi, Sung-Ho;Kim, Young-Man;Jung, Eun-Joo;Oh, Gi-Su;Joo, Sung-Jin;Kim, Sung-Hyun;Kim, Il-Kwang
    • Bulletin of the Korean Chemical Society
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    • v.31 no.12
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    • pp.3567-3572
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    • 2010
  • Black pine barks from the southern region of Korea were extracted using pressurized hot water and the water soluble extracts were then separated in a stepwise fashion using a variety of solvents, column chromatography (CC), thin layer chromatography (TLC), and high pressure liquid chromatography (HPLC). The antioxidant activities of each fraction and the active compounds were determined based on the radical scavenging activities of 2,2-diphenyl-1-picrylhydrazyl (DPPH), reductive potential of ferric ion, and total phenol contents. A DPPH test showed that the half maximal effective concentration ($EC_{50}$ value : $6.59{\pm}0.31\;{\mu}g/mL$) of the ethyl acetate fraction (ca. 0.67%) was almost the same as that of the control compounds and inversely proportional to the value of the total phenol contents. The cell viability of the water extracts was confirmed by methyl thiazol-2-yl-2,5-diphenyl tetrazolium bromide (MTT) with enzyme linked immune sorbent assay (ELISA). Catechin, epicatechin, quercetin and ferulic acid were isolated from the ethyl acetate fraction as active compounds and identified by nuclear magnetic resonance. The antioxidant activity as value of DPPH of each of the separated compounds was lower than the ethyl acetate fraction, and ferulic acid was the lowest among these compounds.

Austenite Stability of Sintered Fe-based Alloy (철계 소결합금의 오스테나이트 안정성)

  • Choi, Seunggyu;Seo, Namhyuk;Jun, Junhyub;Son, Seung Bae;Lee, Seok-Jae
    • Journal of Powder Materials
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    • v.27 no.5
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    • pp.414-419
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    • 2020
  • In the present study, we investigated the austenite stability of a sintered Fe-based nanocrystalline alloy. The volume fraction of austenite was measured based on the X-ray diffraction data of sintered Fe-based nanocrystalline alloys, which were prepared by high-energy ball milling and spark plasma sintering. The sintered alloy samples showed a higher volume fraction of austenite at room temperature as compared to the equilibrium volume fraction of austenite obtained using thermodynamic calculations, which resulted from the nanosized crystalline structure of the sintered alloy. It was proved that the austenite stability of the sintered Fe-based alloy increased with a rise in the amount of austenite stabilizing elements such as Mn, Ni, and C; however, it increased more effectively with a decrease in the actual grain size. Furthermore, we proposed a new equation to predict the martensite starting temperature for sintered Fe-based alloys.

Anti-Rheumatoid Arthritis Effect of the Kochia scoparia Fruits and Activity Comparison of Momordin Ic, its Prosapogenin and Sapogenin

  • Choi, Jongwon;Lee, Kyung-Tae;Jung, Hyun-Ju;Park, Hee-Sun;Park, Hee-Juhn
    • Archives of Pharmacal Research
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    • v.25 no.3
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    • pp.336-342
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    • 2002
  • MeOH extract of Kochia scoparia was fractionated into $CHCl_3-$, EtOAc- and BuOH extracts and the last fraction were hydrolyzed by 3%-NaOH ($MeOH-H_2O$) to compare the bioactivities on antinociceptive and anti-inflammatory effects. Silica gel column chromatography of BuOH fraction afforded a large amount of $3-Ο-{\beta}-D-xylopyranosyl {\;}(1{\rightarrow}3)-{\beta}-D-glucuronopyranosyl$ oleanolic acid (momordin Ic, 4) and that of acid hydrolysate of BuOH fraction gave $3-Ο-{\beta}-D-glucuronopyranosyl oleanolic$ acid (momordin Ib, 3), its 6'-Ο-methyl ester (2) and oleanolic acid (1). Silica gel column chromatography of alkaline hydrolysate afforded a large amount of 4. MeOH extract and both EtOAc- and BuOH fractions were active in the rheumatoidal rat induced Freund's complete adjuvant reagent (FCA) whereas $CHCl_3$ fraction was inactive. Compound 1 and 4 showed significant activities in the same assay but oleanolic acid 3-Ο-glucuronopyranoside (3) showed no activity. These fashions were also observed in carrageenan-induced edema of the rat and in the antinociceptive activity tests undertaken in hot plate- and writhing methods. These results suggest that momordin Ic and its aglycone, oleanolic acid, could be active principles for rheumatoid arthritis.

The Humic Acid Treatment Characteristics by Ionized Gas and Combination with Activated Carbon (이온화가스와 활성탄을 이용한 휴믹산 처리에 관한 연구)

  • Chung, Paul-Gene;Lee, Eun-Ju;Kim, Min-Jeong;Cho, Sun-Young
    • Journal of Korean Society on Water Environment
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    • v.20 no.1
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    • pp.72-77
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    • 2004
  • Laboratory studies were carried out to find out the characteristics of humic acid treatment by activated carbon and ionized gas, In order to increase oxidation power of ionized gas for treating organic matter, we used granular activated carbon. By using $UV_{254}$, easy analysis method, we calculated humic acid concentration and $SCOD_{cr}$ concentration. For an initial concentration of humic acid, 10, 50 and 100ppm, the reaction rate constant by $UV_{254}$ was $8.98{\times}10^{-3}$/min, $5.62{\times}10^{-3}$/min and $4.8{\times}10^{-3}$/min respectively due to the same flow rate of ionized gas. When we added activated carbon to the ionized gas for humic acid treatment, the reaction rate constant increased in 4.13, 3.65 and 3.15 times. So, by using activated carbon in treating humic acid by ionized gas, oxidation power of organic matter by ionized gas was increased. The hydrophobic fraction constitutes 98% of organic matter for humic acid at the beginning. After the treatment using ionized gas for humic acid, the hydrophobic fraction decreased by 63~65% and the hydrophilic one increased by 35~37%. So, it was proved that the treatment increased the hydrophilic fraction in organic matter.