Anti-Rheumatoid Arthritis Effect of the Kochia scoparia Fruits and Activity Comparison of Momordin Ic, its Prosapogenin and Sapogenin
![]() ![]() |
Choi, Jongwon
(College of Pharmacy, Kyungsung University)
Lee, Kyung-Tae (College of Pharmacy, Kyung-Hee University) Jung, Hyun-Ju (Division of Applied Plant Sciences, Sangji University) Park, Hee-Sun (Division of Applied Plant Sciences, Sangji University) Park, Hee-Juhn (Division of Applied Plant Sciences, Sangji University) |
1 | Matsuda, H., Dai, Y., Ido, Y., Ko, S., Yoshikawa, M., and Kubo, M., Studies on Kochiae Fructus III. Antinociceptive and antiinflammatory effects of 70% ethanol extract and its component, momordin Ic from dried fruits of Kochia scoparia L. Biological and Pharmaceutical Bulletin, 20, 1086-1091(1997a) DOI ScienceOn |
2 | Shao, C. -J., Kasai, R., Xu, J. -D., and Tanaka, O., Saponins from roots of Kalopanax septemlobus (Thunb.) Koidz., Ciqiu: Structures of Kalopanaxsaponins C, D, E and F. Chemical and Pharmaceutical Bulletin, 37, 311-314 (1989) DOI |
3 | Choi J. W., Huh, K., Kim, S. H., Lee, K. T., Lee, H. K., and Park, H .J., Kalopanaxsaponin A from Kalopanax pictus, a potent antioxidant in the rheumatoidal rat treated with Freund's complete adjuvant reagent. Journal of Ethnopharmacology, 113-118 (2002b) DOI ScienceOn |
4 | Gine-Larza E. M., Manez, S., Recio, M. C., and Giner, R. M., Oleanonic acid, a 3-oxotriterpene from Pistacia inhibits leukotriene synthesis and has antiinflammatory activity. European Journal of Pharmacology, 428, 137-143 (2001) DOI ScienceOn |
5 | Matsuda, H., Li, Y., Murakami, T., Yarnahara, J., and Yoshikawa, M., Structure-related inhibitory activity of oleanolic acid glycosides on gastric emptying in mice. Bioorg. Med. Chem., 7, 323-327 (1999a) DOI ScienceOn |
6 | Whittle, B.A., The use of change in capillary permeability to distinguish between narcotic and anagesic. British Journal of Pharmacology 22, 246-460 (1949) |
7 | Yoshikawa, M., Shimada, H., Morikawa, T., Yoshizumi, S., Matsumura, N., Murakami, T., Matsuda, H., Hori, K., and Yamahara, J., Medicinal foodstuffs. VII. On the saponin constituents with glucose and alcohol adsorption-inhibitory activity from a food garnish 'tonburi' , the fruit of Japanese Kochia scoparia (L.) Schrad.: Structures of scoparianosides A, B and C. Chem. Pharm. Bull., 45, 1300-1305 (1997) DOI ScienceOn |
8 | Yim, T. K., Wu, W. K., Pak, W. F., Ko, K. M., Hepatoprotective action of oleanolic acid-enriched extract of Ligustrum lucidum fruits is mediated through an enhancement on hepatic glutathione regeneration capacity in mice. Phytotherapy Research, 15, 589-592 (2001) DOI ScienceOn |
9 | Matsuda, H., Dai, Y., Ido, Y., Yoshikawa, M., and Kubo, M., Studies on Kochiae Fructus IV. Anti-allergic effects of 70% ethanol extract and its component, momordin Ic from dried fruits of Kochia scoparia L. Biological and Pharmaceutical Bulletin, 20,1165-1170 (1997b) DOI ScienceOn |
10 | Matsuda, H., Li, Y., and Yoshikawa, M., Roles of capsaicinsensitive sensory nerves, endogenous nitric oxide, sulfhydryls, and prostaglandins in gastroprotection by momordin Ic, an oleanolic acid oligoglycoside, on ethanol-induced mucosal lesions in rats. Life Science, 65, PL27-32 (1999b) DOI ScienceOn |
11 | Yoshikawa, M., Dai, Y., Shimada, H., Morikawa, T., Matsumura, N., Yoshizumi, H., Matsuda, H., and Kubo, M., Studies on Kochiae Fructus. II. On the saponin constituets from the fruit of Chinese Kocia scoparia (Chenopodiaceae): Chemical structures of Kochianosides I, II, III, and IV. Chemical and Pharmaceutical Bulletin, 45, 1052-1055 (1997) DOI ScienceOn |
12 | Winter, C. A., Risley, E. A., and Nuss, G. W., Carrageenin induced edema in hind paw of the rat as an assay for anti-inflammatory drugs. Pro. Soc. Exp. Biol. Med. 111: 544-548(1962) |
13 | Kawamura, N., Watanabe, H., and Oshio, H., Saponins from the roots of Momordica cochinchinensis. Phyto-chemistry, 11,3585-3591 (1988) |
14 | Wen Y., Chen, Y., Cui, Z., Li, J., and Wang, Z., Triterpenoid glycosides from the fruits of Kochia scoparia. Planta Medica, 61,450-452 (1995) DOI ScienceOn |
15 | Choi J. W., Huh, K., Kim, S. H., Lee, K. T., Park, H. J., and Han, Y. N., Antinociceptive and antirheumatoidal effects of Kalopanax pictus extract and its saponin components in excerimental animals. Journal of Ethnopharmacology, 199-202(2002a) DOI ScienceOn |
16 | Kim, D. H., Yu, K. W., Bae, E. A., Park, H. J., and Choi, J. W., Metabolism of Kalopanaxsaponin Band H by human intestinal bacteria and antidiabetic activity of their metabolites. Biological and Pharmaceutical Bulletin, 21, 360-365(1998) DOI ScienceOn |
![]() |