• Title/Summary/Keyword: direct influence area

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Transdermal Delivery of Triamcinolone acetonide Gel by Ultrasound (초음파 조사에 의한 트리암시놀론 아세토니드 겔의 피부투과)

  • Song, Kyung-Suk;Kim, Young-Il;Yang, Jae-Heon
    • Journal of Pharmaceutical Investigation
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    • v.32 no.2
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    • pp.87-93
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    • 2002
  • This study is to enhance drug penetration via skin and investigate anti-inflammation effect following adoption of ultrasound. For this goal gel containing triamcinolone was prepared and the skin penetration rate and the change effects of blood plasma ingredients and serum enzyme were investigated. Using Franz type diffusion cell and the skin of hairless mouse, the permeation enhancing effect of ultrasound was tested. After the injury by direct trauma, the blood test was performed by measuring WBC, lymphocyte, and neutrophyl, and by analyzing CPK and LDH. The ultrasound transducer whose technical specification is geometric area(GA) $1.4\;cm^2$, effective radiation area(ERA) $0.8\;cm^2$, and beam non-uniformity ratio(BNR) 6.0 max was used. The influence of frequency having an effect on skin permeation rate was higher in the case of using 1MHz and continuous treatment. The temperature of receptor phase was not influenced in skin permeation by phonophoresis. Skin permeation increase attended by intensity of ultrasound, the permeation of triamcinolone was accelerated at $2.5\;w/cm^2\;than\;1.0\;w/cm^2$. Following muscle injury phonophoretic group the number of WBC, neutrophil and lympholyte were decreased significantly as compared with both control group and ultrasound group. The result of variation of serum CPK and LDH activity conformed to the phonophoretic effect as same pattern with the variation of WBC, neutrophil and lymphocyte.

Changes of Landscape Structure for the Recent 20 Years in the Wangsuk Stream Basin of the Central Korea

  • Lee, Chang-Seok;Cho, Yong-Chan;Shin, Hyun-Chul;Lee, Seon-Mi
    • Journal of Ecology and Environment
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    • v.29 no.4
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    • pp.405-410
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    • 2006
  • Landscape changes for 20 years between 1981 and 2001 in the Wangsuk stream basin located on the central Korea were investigated on the basis of physiognomic vegetation map made from the aerial photograph interpretation and field check. Changes of landscape structure were noticeable in agricultural field and forest landscape elements. Changes in the agricultural fields due to transformation of agricultural pattern into the institutional agriculture dominated landscape change, although urbanization also contributed to such change. The former change due to change of food production structure originated from socio-economic development during this period and the latter to the overpopulation of Seoul. As energy sources for heating and cooking, fertilizer, and fodder for livestock transform from plant materials to fossil fuel, manufactured one, and grain, succession of forest escaped from direct human disturbance dominated change of landscape structure in forested land. Differently from the positive landscape change in the upper area, change in the lower area deteriorated landscape quality by increasing artificial land. It was estimated that such landscape deterioration in the Wangsuk stream basin would influence water quality of the stream. In order to realize sustainable land-use against such environmental degradation, systematic environmental management based on landscape ecological perspective such as "an eco-plan for creating riparian vegetation belt," which is under preparation by Ministry of Environment, was recommended.

A THREE DIMENSIONAL FINITE ELEMENT ANALYSIS WITH CAVITY DESIGN ON FRACTURE OF COMPOSITE RESIN INLAY RESTORED TOOTH (복합레진 인레이 수복시 와동형태에 따른 치아파절에 관한 유한요소법적 연구)

  • Kim, Chull-Soon;Min, Byung-Soon
    • Restorative Dentistry and Endodontics
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    • v.19 no.1
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    • pp.231-254
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    • 1994
  • Fracture of cusp, on posterior teeth, especially those carious or restored, is major cause of tooth loss. Inappropriate treatments, such as unnecessarily wide cavity preparations, increase the potential of further trauma and possible fracture of the remaining tooth structures. Fracture potential may be directly related to the stresses exerted upon the tooth during masticatory function. The purpose of this study is to evaluate the fracture resistance of tooth, restored with composite resin inlay. In this study, MOD inlay cavity prepared on maxillary first premolar and restored with composite resin inlay. Three dimensional finite element models with eight nodes isoparametric solid element, developed by serial grinding-photographing technique. These models have various occlusal isthmus and depth of cavity, 1/2, 1/3 and 1/4 of isthmus width and 0.7, 0.85 and 1.0 of depth of cavity. The magnitude of load was 474 N and 172 N as presented to maximal biting force and normal chewing force. These loads applied onto ridges of buccal and lingual cusp. These models analyzed with three dimensional finite element method. The results of this study were as follows : 1. There is no difference of displacement between width of occlusal isthmus and depth of cavity. 2. The stress concentrated at bucco-mesial comer, bucco-disal comer, pulpal line angle and the interface area between internal slopes of cusp and resin inlay. 3. The vector of stress direct to buccal and lingual side from center of cavity, to tooth surface going on to enamel. The magnitude of vector increase from occlusal surface to cervix. 4. The crack of tooth start interface area, between internal slop of buccal cusp and resin inlay. It progresses through buccopulpal line angle to cervix at buccomesial and buccodistal comer. 5. The influence with depth of cavity to fracture of tooth was more than width of isthmus. 6. It would be favorable to make the isthmus width narrower than a third of the intercuspal distance and depth of cavity is below 1 : 0.7.

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Bond Stress-Strain Predict Model with Inner Cover Thickness of Steel Wire Used in Void Deck Plate (중공 데크플레이트에 사용된 철선의 내부피복두께에 따른 부착응력-변형률 예측모델)

  • Kim, Hee-Hyeon;Choi, Chang-Sik
    • Journal of the Architectural Institute of Korea Structure & Construction
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    • v.34 no.1
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    • pp.41-51
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    • 2018
  • In case of evaluating the bond stress of a void deck plate using a wire steel, there is no standard formula considering both the influence on the void and the type of the reinforcing bar. Therefore we proposed a model equation considered the bond characteristics of the void deck plate. A total of 46 specimens was carried out a direct pull-out test and the test variables were the presence of a void body, type of reinforcing bar, the inner cover thickness according to the location of reinforcing bars and bond region. As a result of the comparison between the steel bar and steel wire, the bond stress of the steel wire with the relative rib area of 0.071 is 4.5 ~ 28.58% lower than that of the steel bar with 0.092 and the bond stress reduction rate increases when the inner cover thickness is insufficient. In the case of the inner cover thickness of $1.7d_b$ and $2.7d_b$, the bond stress was reduced to 48.7 ~ 68.4%. In the inner cover thickness was $4.9d_b$ and $5.2d_b$, the bond stresses were equivalent to those of the solid specimens. It was confirmed that the average bond stress and strain were affected by the inner cover thickness. Therefore the predicted model for one module of the void deck plate is proposed and verified by considering the bond characteristics of the void deck plate.

The Pagan-Period and the Early-Thai Buddhist Murals: Were They Related?

  • Poolsuwan, Samerchai
    • SUVANNABHUMI
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    • v.6 no.1
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    • pp.27-65
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    • 2014
  • Flourishing in the Central Dry Zone of Burma during a period from the mid-eleventh to the late-thirteenth century A.D., the historical kingdom of Pagan was one of the major Buddhist centers in Southeast Asia. The significance of Pagan as an important pilgrimage site of the region, where numerous relics of the Buddha were enshrined, had been maintained until long after the fall of its civilization. It is evident that the artistic influences of Pagan, particularly in the architectural and decorative domains, had been transmitted to various other Buddhist civilizations in the area. This study provides a detailed analysis on the relationships between the mural tradition of Pagan and those of its neighboring civilizations in Thailand-of the Ayutthayā, Lānnā and Sukhothai schools-dating from after the Pagan Period in the fourteenth century to the sixteenth century. Surprisingly, as the analysis of this study has suggested, such relationships seemed to be trivial, more on a minor stylistic basis than on substantial ideological and iconographic grounds. They suggest that transmission of the complex idea and superb craftsmanship of the mural tradition would not have been maintained adequately at Pagan after its civilization, probably due to the lack of royal patronage. It would have been extremely difficult for foreign pilgrims who visited Pagan after its dynastic period to appreciate the surviving murals of this lost tradition in terms of their complex programs and associated symbolism. Also, there had been a new center of the Sinhalese Buddhism firmly established in the Martaban area of lower Burma since the mid-fourteenth century that outcompeted Pagan in terms of supplying the new Buddhist ideas and tradition. Its fame spread wide and far among the Buddhist communities of Southeast Asia. Later, these Buddhist communities also established direct contact with Sri Lanka. The Sukhothai murals and the Ayutthayā murals in the crypt of Wat Rātchaburana, dating from the fourteenth/fifteenth century, show obvious Sri Lankan influence in terms of artistic style and Buddhist iconography. They could be a product of these new religious movements, truly active in Southeast Asia during that time.

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An Empirical Study on Emotional Intensity and the Influence of Product Involvement in the Context of the Integrative Framework

  • Pradip Hira, Sadarangani;Sanjaya S., Gaur
    • Journal of Global Scholars of Marketing Science
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    • v.12
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    • pp.99-119
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    • 2003
  • A model is proposed for the role of emotional intensity of a web site, and the moderating influence of product involvement, in the Integrative Framework of persuasion (Meyers-Levy and Malvaiya 1999). The model also appropriately operationalizes the constructs emotional intensity of a web site and product involvement The three routes to persuasion, Central, Peripheral, and Experiential correspond to high, moderate, and low involvement (Meyers-Levy and Malaviya 1999). The involvement construct is measured from message recipients using the Personal Product Inventory (Pill, which was developed to capture the concept of product involvement (Zaichkowsky 1985). The conceptualization of the Personal Product Inventory is a contextrree measure that also has robust psychometric properties when applied to advertisements (Zaichkowsky 1994). The propositions highlight the expected importance of emotional intensity of a web site. The moderating influence of product involvement is also proposed. Specifically, what this work proposes is that the emotional intensity of a product site has a larger impact on attitude change under low product involvement, as opposed to moderate product involvement. Support for this reasoning can be found in the persuasion literature (Petty et al 1986). The Petty et al (1986) frame work is a dual process descriptive and predictive frame work in the area of altitude formation and change. Recently, Myers Levy and Malaviya (1999) have proposed a tri-process framework. This is in tum based on the dual process model of Petty et al. (1986). The study outlined in this paper aims to deepen the Meyers Levy and Malaviya (1999) and frame work. The propositions outlined in the model are empirically tested using a repeated measures experimental design. The emotional intensity is measured using a scale that is based on experts judgments. Using a paired comparison t-test two sites are determined to be of high and low emotional intensity. The model is tested using a repeated measures experimental design. The first independent variable Emotional Intensity of the site is manipulated. The Second independent variable, Personal Product Inventory is measured. While, the dependent variable, product altitude change will also be measured. Utilizing Analysis of Variance (ANOVA) the data is analyzed using SPSS. The results suggest that besides the rational content of messages their emotional content can also influence attitude change. Specifically, it is proposed that the manipulation of emotional intensity of a product Web site has a greater impact on product altitudes under high and low product involvement conditions, rather than moderate product involvement. However, the results for product involvement as a continuous variable has a p value of 0.09. Further, the results for three levels of product involvement were far from significant. For two levels of product involvement also, the results were insignificant, the p value approached 0.20. This evidence indicates that it is premature to conclude that there are three routes to persuasion. A caveat, however, must be added, in that the manipulations may not have been strong enough to test the proposed hypotheses. Further, undoubtedly, there is unequivocal evidence the emotional intensity of a product Web site, as measured here, has a direct impact on product attitudes.

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A Clinical Review on the Transoral Approach to the Fractures of The Mandible (구내 접근법에 의한 하악골 골절 치료에 대한 임상적 고찰)

  • Park, Hyung-Sik;Kwon, Jun-Ho;Chung, Seong-Hoon
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.11 no.1
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    • pp.79-86
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    • 1989
  • The is a retrospective study on the transoral approach to open reduction of the Mandibular fractures. Our study was based on a series of 64 patients with mandibular fractures among 99 patients of facial bone fractures who had been treated by transoral approach with or without extraoral approach at Department of Oral and Maxillofacial Surgery, Yonsei Medical Center, Yonsei University from January 1981 to October 1988. We studied favorite sites of open reduction, fixation methods, results and prognosis related to transoral approaches of Mandibular fractures, and which compared with extraoral approaches. The results obtained are as follows : 1. The transoral open reduction was used more frequently in Mandibular fractures(64.6%) than Midfacial bone fractures(35.4%). Among 64 patients of mandibular fractures, 47 patients(73.4%) were treated only by transoral approach and others(26.6%) were treated by both trans- and extra-oral approach. Among 92 sites of mandibular fractures, 75 sites(81.5%) were treated by transoral approach and 17(18.5%) were treated by extraoral approach. 2. The most favorite site for transoral approach compared with extraoral approach was Symphysis(100%), and Angle(62.5%) was next in order of frequency on Mandibular fractures. 3. Direct Interosseous Wiring(DIW) was most commonly used for fixation(64.6%) and Miniplate osteosynthesis was used next in 28.1%. 4. Simple(39.1%) and Compound(52.2%) fractures were frequently indicated for transoral approach, however comminuted fractures were rarely indicated. 5. The direction of fracture lines on Angle of the mandible did not influence to determine whether transoral approach should be selected or not. However this area seemed to be more difficult to reduce exactly by transoral procedure than other areas because simultaneous superior and inferior fixation was applied predominantly on this area. 6. The success rate of reduction and fixation analyzed from us was more excellent in Direct Interosseous Wiring(29/53=54.7%) than in Rigid Internal Fixation(9/29=31.0%). But it might be depended upon various factors as like as sugeon's skill. 7. The postoperative complication due to transoral open reduction of mandible was not high(12.0%) and this rate was similar with other published reports.

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A Study on Safe Separation Distance between Tunnel and Interchange (터널과 입체 교차로간의 안전한 이격거리 연구)

  • Lee, In-Bae;Kim, Nakseok
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.39 no.2
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    • pp.273-279
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    • 2019
  • Development of mountain area is increasing due to the demand for improvement of traffic convenience and development of underdeveloped area. Therefore, there frequently are sections where tunnels and interchanges are located close to each other. These sections do not only affect tunnel planning, types and length of interchanges, but also affect more on route selection. In Korea, several design criteria present each reference value but these values are very similar. In the situation, the minimum value among them is usually applied when planning roads and it could cause traffic safety problems in different site conditions. In this study, the problems of design speed, illuminance adaptation distance, and lane change intervals are analyzed by simulating the cases that the problem could occur when calculating the separation distance between tunnel and interchange. The results obtained from this study can be summarized as following: the driving speed should be applied in case that the site has a big gap between design speed and driving speed because the uniform application of the design speed is not safe; the illuminance adaptation distance should include the influence distance in the section affected by the direct light; in addition, the lane change distance should include the time to perceive the situation of the next lane after the lane change in the section required for successive lane change.

Analysis of Environmental Odor Factors for Dorim Stream in Gwanak-gu, Seoul (서울시 관악구 도림천 복개 정도에 따른 환경 악취 요인 분석)

  • Soyoung Park;Gokce Nur Ayaz;Heewon Kim;Hyungkee Yoon;Taehong Kwon;Sungkyoon Kim
    • Journal of Environmental Health Sciences
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    • v.50 no.2
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    • pp.83-92
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    • 2024
  • Background: In this study, we investigate the rapid increase in environmental odors and notable rise in civil complaints near Dorim Stream in the Gwanak-gu area of Seoul. Objectives: This study aims to identify the causal compounds responsible for environmental odors in the Dorim Stream and investigate the structural characteristics of the stream that influence odor generation. Methods: The research methodology involved setting up 41 sampling points, selecting panels for direct sensory evaluation to assess odor intensity, measuring dissolved oxygen and hydrogen sulfide concentrations, and using all-in-one low-temperature desorption gas chromatography (ATD-GC) and thermal desorption-gas chromatography-mass spectrometry (TD-GC/MS) analysis to identify odor-causing compounds. Results: The evaluation of Dorim Stream revealed that in areas with complete meandering, there were lower dissolved oxygen levels (4.5±2.67 mg/L) and higher odor intensity (4.0±0.92), while in partially meandering sections, higher dissolved oxygen levels (7.8±1.15 mg/L) and lower odor intensity (2.8±1.06) were observed. Hydrogen sulfide levels measured with sensors increased with higher temperatures, especially in the afternoon hours (12:00~14:00). Acetaldehyde was the dominant odor compound detected in both the Bonglim Bridge (0.4 ppm) area and Guro Bridge area (0.867 ppm), with concentrations more than twice as high near Guro Bridge. Odor-causing compounds identified by TD-GC/MS indicated a pungent, sulfurous odor in the Guro Bridge area and a musty odor in the Bonglim Bridge area. Conclusions: This study categorizes and analyzes the sources of odor in Dorim Stream in Seoul based on meandering patterns and the distribution of sewage facilities, highlighting the potential odor issues associated with combined sewage systems and sewer junctions and suggesting policy improvements.

A Analysis on Preference of Funeral Type by Socioeconomic Characteristics using Nested Logit Model (네스티드로짓모형을 활용한 사회경제적 특성에 따른 장사유형 선호 분석)

  • Joo, Ho Sang;Choi, Yeol
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.39 no.6
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    • pp.933-943
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    • 2019
  • The purpose of this study is to identify determinants for preferred funeral methods depending on socio-economic characteristics. In South Korea, the Act on Funeral Services, Etc. categorizes funeral methods into burial, inurnment, and natural burial. This study empirically analyzes how and what socio-economic characteristics affect choices among these three categories. Data is collected from Social Survey 2017 and funeral facilities in the country. The data to be analyzed is developed in terms of a hierarchy which puts the burial and cremation methods in an upper class and the inurnment and natural burial methods in a lower class. Based on this data, a nested logit model is employed to conduct empirical analysis. The analysis indicates that those characteristics that have a statistically significant influence on preferred methods include gender, age, householder, marriage, satisfaction with life, class awareness, monthly income, housing type, housing tenure type, and living in city area. Each variable's modulus of calculated direct and cross elasticity need to be used to analyze the outcome of a nested logit model. In this study, the modulus of direct and cross elasticity are determined for the significant variables. The calculated direct elasticity is applied to analyze the likelihood of choosing each funeral method when there are changes in the significant variables. When a particular method has been selected, on the other hand, the cross elasticity is utilized to analyze changes to the likelihood of choosing the other methods. One of the most notable results is related to natural burial. In order to meet the demand for natural burial, it is necessary to provide more burial sites and raise awareness of natural burial. This will facilitate the efficient use of national territorial space.