• 한국해양공학회지
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• 제32권3호
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• pp.166-176
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• 2018

This paper presents a numerical sensitivity analysis for the simulation of the motion performance of an offshore structure in waves using computational fluid dynamics (CFD). Starting with 2D wave simulations with varying numerical parameters such as grid spacing and CFL value, proper numerical conditions were found for accurate wave propagation that avoids numerical diffusion problems. These results were mapped on 2D error distributions of wave amplitude and wave length against the numbers of grids per wave length and per wave height under a given CFL condition. Finally, the 2D numerical sensitivity result was validated through CFD simulation of the motion of a FPSO in waves showing good accuracy in motion RAOs compared with existing potential flow solutions.

• 한국정보통신학회논문지
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• 제17권10호
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• pp.2461-2465
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• 2013

본 논문은 광섬유 브래그 격자의 방사선 민감도에 대한 수소로딩 공정의 영향에 대해서 연구하였다. 게르마늄이 함유된 광섬유에 수소로딩 기간을 달리하여 광섬유 브래그 격자를 제작하였다. 광섬유 브래그 격자는 총 18 kGy 감마선에 조사하여 방사선에 의한 브래그 파장의 변화를 측정하였고, 방사선 조사 후에는 반치대역폭과 온도 감도 계수의 변화를 평가하였다. 수소로딩 조건에 따라서 방사선에 의한 브래그 파장의 변화는 약 2 배 이상의 차이를 보였다.

• Environmental Analysis Health and Toxicology
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• 제25권1호
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• pp.19-26
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• 2010

Discharged materials from the point or non-point source are released into the sea, and as the results, marine environment is directly affected. We must estimate the impacts of contaminants to marine pollution rapidly and accurately. Therefore, it is needed on early warning system for appreciating marine environmental impacts, and required a bioassay to evaluate abnormal changes. A bioassay test was developed to examine the effects of heavy metal contaminants on the early life stages of the marine annimals. We have studied the effects of metals on early development of a sea urchin species, Strongylocentrotus intermedius. S. intermedius embryos were tested with six metals (Cu, Ag, Zn, Cd, Cr, Ni) and showed the highest sensitivity to Cu as well as the lowest sensitivity to Cd. The order of biological impact for metals was Cu>Ag>Ni>Zn>Cr>Cd. In accordance with the results, sea urchins embryos can provide biological criteria for seawater quality assessment. The sensitivity of developmental bioassay whith S. intermedius is at intermediate level among marine organisms commonly used in aquatic bioassays. And this sea urchin can be routinely employed as a test organism for ecotoxicity assays.

• 가정과삶의질연구
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• 제32권5호
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• pp.193-205
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• 2014

The purpose of this research is to gather basic data to make nursery teachers' role clear and to suggest a way to improve their expertise by investigating their sensitivity and expertise. To fulfill this aim, this research was performed by targeting 180 nursery teachers responsible for infant classes in national, public, and private nursery schools. To measure the nursery teachers' sensitivity, Gerber's (2003) teacher sensitivity indicator is used. And to measure the efficacy of teaching play, the indicator, which was developed by E. Shin, Y. Yu and H. Park (2004), was used through modification and complement. Also for measuring the teacher's expertise, research data were collected by the generalized and modified questionnaire which was used in H. Yoon's (2010) research. The results of the analysis of collected data show that the teacher group with higher sensitivity in the infant class shows meaningfully higher professional ethics, higher performance, and higher recognition of expertise than the teacher group with lower sensitivity. And the teacher group with higher awareness of the efficacy of play shows higher professional ethics, higher performance, and higher recognition of expertise than the teacher group with lower sensitivity. too. Also, the results of the analysis of the correlation between the infant teacher's sensitivity, efficacy of teaching play, and recognition of expertise show that the teacher's sensitivity has a static correlation with the total points of social necessity, professional ethics, fairness, teacher's performance, and recognition of expertise. When we generalize the research results, we find that positive sensitivity and higher efficacy of teaching play make the infant class teacher's expertise recognition higher.

• 한국해양공학회지
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• 제23권1호
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• pp.1-6
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• 2009

The paper describes results of a sensitivity study on an optimum mooring cost as a function of safety factor and allowable maximum offset of the offshore floating structure by finding the anchor leg component size and the declination angle. A harmony search (HS) based mooring optimization program was developed to conduct the study. This mooring optimization model was integrated with a frequency-domain global motion analysis program to assess both cost and design constraints of the mooring system. To find a trend of anchor leg system cost for the proposed sensitivity study, optimum costs after a certain number of improvisation were found and compared. For a case study a turret-moored FPSO with 3 ${\times}$ 3 anchor leg system was considered. To better guide search for the optimum cost, three different penalty functions were applied. The results show that the presented HS-based cost-optimum offshore mooring design tool can be used to find optimum mooring design values such as declination angle and horizontal end point separation as well as a cost-optimum mooring system in case either the allowable maximum offset or factor of safety varies.

• Corrosion Science and Technology
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• 제17권4호
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• pp.193-201
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• 2018

In order to suppress $CO_2$ emission and protect passengers in case of vehicle collision, continuous efforts are being made to increase the application ratio and tensile strength of advanced high strength steels used in the manufacturing of automotive body. Simultaneously, hydrogen embrittlement which was not a concern in the past has currently become a major issue due to microstructure that is sensitive to hydrogen uptake. The sensitivity increases with residual stress and hydrogen uptake content. Many automotive OEM companies and mill makers are setting specifications to control hydrogen embrittlement. The factors which lead to hydrogen embrittlement are material sensitivity, residual stress, and hydrogen concentration; researches are in progress to develop countermeasures. To reduce material sensitivity, mill makers add high energy trap elements or microstructure refinement elements. Automotive OEM companies design the car parts not to concentrate local stress. And they manage the levels to not to exceed critical hydrogen concentration. In this article, we have reviewed hydrogen embrittlement evaluation methods and corresponding solutions that are being studied in automobile manufacturing industries and mill makers.

• 한국가축번식학회지
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• 제9권2호
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• pp.133-139
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• 1985

An immunoassay may be defined as an analytical procedure involving the competitive reaction between a limiting concentration of specific antibody and two populations of antigen, one of which is labelled or immobillized. The advent of immunoassay has revolutionised our knowledge of reproductive physiology and the practice of veterinary and clinical medicine. Radioimmunoassay (RIA) was the first of these methods to be developed, which meausred the analyte with good sensitivity, accuracy and precision (1,2). The essential components of RIA are:-(i) a limited concentration of antibodies, (ii) a reference preparation, and (iii) an antigen labelled with a radioisotope (usually tritium or iodine-125). Most procedures invelove isolating the antibody-bound fraction and measuring the amount of labelled antigen. Good facilities are available for scintilltion counting, data reduction nd statistical analysis. RIA is undergoing refinement through:-(i) the introduction of new techniques to separate the antibody-bound and free fractions which minimize the misclassification of labelled antigen into these compartments, and the amount of non-specfic binding. (3), (ii) the development of non-extration for the measurement of haptens (4), (iii) the determination of a, pp.rent free (i.e. non-protein bound) analytes (5), and (iv) the use of monoclonal antibodies(6). In 1968, Miles and Hales introduced in important new type of immunoassay which they termed immunora-diometric assay (IRMA) based on t도 use of isotopically labelled specific antibodies(7) in a move from limited to excess reagent systems. The concept of two-site IRMAs (with a capture antibody on a solid-phase, and a second labelled antibody to a different antigenic determinant of the analyte) has enabled the development of more sensitive and less-time consuming methods for the measurement of protein hormones ovar wide concentration of analyte (8). The increasing use of isotopic methos for diverse a, pp.ications has exposed several problems. For example, the radioactive half-life and radiolysis of the labelled reagent limits assay sensitivity and imposes a time limit on the usefulness of a kit. In addition, the potential health hazards associated with the use and disposal of radioactive cmpounds and the solvents and photofluors necessary for liquid scientillation counting are incompatable with the development of extra-laboratory tests. To date, the most practical alternative labels to radioisotopes, for the measurement of analytes in a concentration > 1 ng/ml, are erythrocytes, polystyrene particiles, gold sols, dyes and enzymes or cofactors with a visual or colorimetric end-point(9). Increased sensitivity to<1 pg/ml may be obtained with fluorescent and chemiluminescent labels, or enzymes with a fluorometric, chemiluminometric or bioluminometric end-point. The sensitivity of any immunoassay or immunometric assay depends on the affinity of the antibody-antigen reaction, the specific activity of the label, the precision with which the reagents are manipulated and the nonspecific background signal (10). The sensitivity of a limited reagent system for the measurement of haptens or proteins is mainly dependent upon the affinity of the antibodies and the smalleest amount of reagent that may be manipulated. Consequently, it is difficult in practice to improve on the sensitivity obtained with iodine-125 as the label. Conversely, with excess reagent systems for the measurement of proteins it is theoretically possible to increase assay sensitivity at least 1000 fold with alternative luminescent labels. To date, a 10-fold improvement has been achieved, and attempts are being made to reduce the influence of other variables on the specific signal from the immunoreaction.

• Safety and Health at Work
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• 제9권4호
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• pp.473-478
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• 2018

Background: Multiple Chemical Sensitivity (MCS) is an acquired disease which etiology remains unknown. It is characterized by the development of sensitivity to certain chemical products. Most of the hypotheses formulated to explain the syndrome associate it to a previous exposition to some kind of volatile chemical. University researchers in chemical laboratories suffer a phenomenon of multi-exposition to chemical agents at low concentration during long periods of time although in an irregular form. Many of these chemical agents have similar properties to those suspicious of causing MCS. This article studies the prevalence of MCS in laboratory researchers. Methods: The study group is university researchers in chemical laboratories. The control group was obtained from administrative personnel who work in the same universities and therefore, are not exposed to chemical products from the laboratories, but have the same exposition to the rest of environmental polluting agents from the area and from the buildings of the university. In this study, it is used the Quick Environmental Exposure and Sensitivity Inventory (QEESI) (sensitivity of 92%/specificity of 95%). Results: The results showed that the prevalence of MCS for the university researchers is not related to exposition by inhalation to multiple chemical agents, at low concentration. Conclusions: The results disagree with one of the main etiological hypotheses of MCS, which is based on the existence of hypersensitive people, who presents a response after prolonged expositions to very low concentrations during a long period of time.

• 동력기계공학회지
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• 제5권4호
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• pp.82-89
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• 2001

To design a structural or a mechanical system with the best performance, the main procedure of a typical design usually consists of repeated modifications of design parameters and the investigation of the system response for each set of these parameters. But this procedure requires much time, effort and experience. Sensitivity analysis can provide systematic information for improving performance of a system. The author has studied on the development of the structural analysis algorithm and suggested recently the transfer stiffness coefficient method(TSCM). This method is very suitable algorithm to a personal computer because the concept of the TSCM is based on the transfer of the nodal stiffness coefficients which are related to force and displacement vectors at each node. In this paper, a new sensitivity analysis algorithm using the concept of the TSCM is formulated for the computation of state variable sensitivity in static problems. The trust of the proposed algorithm is confirmed through the comparison with the computation results using existent sensitivity analysis algorithm and reanalysis for computation models.

• 대한한의학회지
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• 제28권3호통권71호
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• pp.173-182
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• 2007

Objective : To develop an integrated curriculum for acupuncture treatment and pain sensitivity practice, and discuss its usefulness. Method : We established an integrated practice program incorporating acupuncture and pain on physiology perspectives, and measured pain sensitivity at Yin (PC6${\sim}$PC4) and Yang (TE5${\sim}$TE9) meridians before and after the acupuncture treatment. Results : The Yang (39.4${\pm}$23.5) and Yin (46.0${\pm}$25.5) meridians have significantly different degrees of pain sensitivity (n=118, p=0.018). Pain sensitivity was significantly decreased after acupuncture treatment at Yang (54.63${\pm}$28.02/ 40.81${\pm}$29.39) and Yin (56.13${\pm}$27.88/ 38.72${\pm}$25.17) meridians (n=16, p<0.001). Discussion and Conclusion : The difference between the Yin and Yang meridians can be materialized in this integrated practice curriculum model. The effectiveness of this integrated class and suggestions for improvement of integrated curricula were discussed.