• 제목/요약/키워드: dendritic

검색결과 768건 처리시간 0.032초

HOPG 기판 위에 누적된 Dendritic Silsesquioxane (G3-9Ph) LB 박막의 모폴로지 분석 (Study on Morphology of Dendritic Silsesquioxane (G3-9Ph) LB Films Deposited on HOPG)

  • 성기찬;이지윤;신대식;김정균;권영수
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2009년도 제40회 하계학술대회
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    • pp.1234_1235
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    • 2009
  • The Langmuir-Blodgett (LB) method has been one of the most suitable techniques for fabricating organic thin films with well-controlled structures, compositions and thickness at the molecular level. We investigated the surface activity of dendrimer films at air-water interface by $\pi$-A isotherm. Also, we attempted to fabricate a G3-9Ph dendritic silsequioxane LB films. And their surface morphologies were observed by atomic force microscopy (AFM).

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IL -1${\beta}$ Expression of Cefodizime on Dendritic cell and Macrophage

  • Joo, Seong-Soo;Kwon, Hee-Seung;Lee, Do-Ik
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.306.3-307
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    • 2002
  • According to recent studies. cefodizime. a third generation cephalosporin antibiotic agent. may potentially have the capability of stimulating chemotactic activity of neutrophils and monocytes as well as the strong immuno-modulator. We have studied to see if cefodizime can be a potential substance inducing an Immunological activities on immune cells. such as dendritic cells and macrophages. In experimental process. dendritic cell and macrophage were taken from mice and mixed with 10${\mu}\ell$/$m\ell$. 50$${\mu}\ell$/$m\ell$, 100${\mu}\ell$/$m\ell$.cefodizime and 1$${\mu}\ell$/$m\ell$ IFN-${\gamma} 10U/$m\ell$+LPS. (omitted)

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Dendritic web으로 성장된 규소 결정속의 결함 규명 (Characterization of the structural defects in the dendritic web-grown silicon ribbon)

  • Kim, Young-Kwan
    • 한국결정성장학회지
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    • 제4권3호
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    • pp.276-283
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    • 1994
  • Dendritic-web 방법으로 성장된 규소의 결정속에 존재하는 여러 결합을 화학적 etching 방법으로 규명하였다. Twin plan상에 존재하는 전위의loop이 관찰되었고 이들은 규소의 self - interstital이 condensation되어서 형성된 것으로 판단된다. 이들 규소의 self-interstitial은 응고 온도로 부터의 급냉에 의하여 혹은 oxide precipitation에 의하여 생성되 것으로 여겨진다.

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Receptor activator of nuclear factor-κB ligand in T cells and dendritic cells communication

  • Nam, Sun-Young;Jeong, Hyun-Ja
    • 셀메드
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    • 제3권1호
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    • pp.3.1-3.3
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    • 2013
  • The receptor activator of NF-${\kappa}B$ ligand (RANKL), a member of the tumor necrosis factor ligand family, has extensive functions beyond osteoclast development. RANKL is expressed in many immune cells such as osteoblasts, osteocytes, marrow stromal cells, activated T cells, synovial cells, keratinocytes, and mammary gland epithelial cells as well as in various tissues. The ligation of RANK by RANKL promotes dendritic cells (DCs) survival through prosurvival signals and the up-regulation of the anti-apoptotic proteins Bcl-2 and Bcl-$x_L$ and plays a crucial role in DCs-mediated Th1 differentiation. Therefore, RANKL plays an important role in the regulation of DCs/T cells-mediated specific immunity. This review will briefly inform our current understanding of the role of RANKL signaling in T cells-DCs communication in the immune system.

Effect of atorvastatin on dendritic cells of tubulointerstitium in diabetic rats

  • Tu, Yafang;Jia, Ruhan;Ding, Guohua;Chen, Ling
    • BMB Reports
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    • 제43권3호
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    • pp.188-192
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    • 2010
  • Inflammatory reactology has become increasingly important in diabetic kidney disease. In this study, we estabilished STZ-induced diabetic rat model to investigate whether dendritic cells (DCs) mediated tubulointerstitial damages, and whether the effects by DCs were mediated by P-selectin expression and can be inhibited by atorvastatin. The study demonstrated that there was an accumulation of DCs in diabetic rats mediated by P-selectin. It also showed the accumulation of DCs and expression of P-selectin was closely correlated with the degree of renal tubulointerstitial injury. These effects were markedly attenuated by atorvastatin. Thus, DCs play a role in tubulointerstitial damages, atorvasttin can prevent renal tubulointerstitium from damage by inhibiting the P-selectin expression and DCs migration.

Synthesis of Nanomaterials such as fluorescent-magnetic Nanoclusters and Frequency Doubling Nanowires for Bioapplications

  • Jeong, Jinhoo;Kim, Seungwook;Kim, Woong
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 2014년도 제46회 동계 정기학술대회 초록집
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    • pp.132.1-132.1
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    • 2014
  • Fluorescent-magnetic nanoclusters were synthesized for biomedical applications. The nanoclusters consisted of superparamagnetic core-nanoclusters, highly fluorescent shell of nanocrystals, and lipid A. Magnetic cores were used for both magnetic resonance imaging (MRI) and cell separation. Fluorescent shell was used for optical imaging. The lipid-A-loaded nanoclusters were up-taken by dendritic cells via phagocytosis, which successfully activated dendritic cells. The dendritic cells were migrated to lymph nodes and spleen of mice. The results showed that our novel nanoclusters can play a role as an efficient optical and magnetic imaging, a cell separating and a pathogen mimetic agent at the same time. Additionally, synthesis of wavelength conversion nanowires will be discussed, which may be used as an optical nanoprobe in biological studies.

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Conducting Behavior of Carbosilane Dendrimers Including Palladium Ions

  • Kim, Chungkyun;Koo, Bon-Won;Lee, Sang-Bak;Song, Chung-Kun
    • Macromolecular Research
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    • 제10권3호
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    • pp.178-180
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    • 2002
  • The conducting behavior of dendritic carbosilanes including palladium ions (Pd$^{2+}$) has been measured. The palladium ion containing dendrimers were prepared by the addition of palladium dichloride to double-layered dendritic carbosilanes, which consist of phenylethynyl groups (-C≡CPh) on the outmost periphery as well as phenylethenyl and propyleneoxy groups (-CH=CPh- and (CH$_2$)$_3$O-) in the inner shell. By measuring conductivities, palladium ion containing dendrimers revealed an increasing tendency according to the increasing number of double bonds in the inner shells of dendritic carbosilanes.s.

아공정 Al-Si 합금에서 Si 함량과 냉각속도에 따른 제이차수지상간격의 변화 (Change of Secondary Dendrite Arm Spacing of Hypoeutectic Al-Si Alloys according to Si Content and Cooling Rate)

  • 박경섭;김희수
    • 한국주조공학회지
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    • 제37권4호
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    • pp.108-114
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    • 2017
  • In this study, we investigated the effect of the Si content on the secondary dendrite arm spacing (SDAS) of hypoeutectic Al-Si binary alloys in the range of 4~10 wt% Si. Cooling curves were measured during the solidification of the alloy cast in a step-wise mold. We compared two kinds of solidification time: the first is the total solidification time for both dendritic and eutectic growth, and the second is the solidification time for only dendritic growth. The proportional constant in the relationship between SDAS and cooling rate was estimated, as this constant represents the stability of the cast microstructure. The proportional constant decreased with the Si contents from 4 wt% to 8 wt%, and it remains relatively uniform with up to 10 wt% of Si.

Regulation of Intestinal Immune System by Dendritic Cells

  • Ko, Hyun-Jeong;Chang, Sun-Young
    • IMMUNE NETWORK
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    • 제15권1호
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    • pp.1-8
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    • 2015
  • Innate immune cells survey antigenic materials beneath our body surfaces and provide a front-line response to internal and external danger signals. Dendritic cells (DCs), a subset of innate immune cells, are critical sentinels that perform multiple roles in immune responses, from acting as principal modulators to priming an adaptive immune response through antigen-specific signaling. In the gut, DCs meet exogenous, non-harmful food antigens as well as vast commensal microbes under steady-state conditions. In other instances, they must combat pathogenic microbes to prevent infections. In this review, we focus on the function of intestinal DCs in maintaining intestinal immune homeostasis. Specifically, we describe how intestinal DCs affect IgA production from B cells and influence the generation of unique subsets of T cell.

Facile Synthesis of Aldehyde-focal Fréchet Type Dendrons and Dendrimers via Staudinger/Aza-Wittig Reactions

  • Han, Seung-Choul;Jin, Sung-Ho;Lee, Jae-Wook
    • Bulletin of the Korean Chemical Society
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    • 제32권10호
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    • pp.3624-3628
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    • 2011
  • Fr$\acute{e}$chet-type dendritic benzaldehydes were efficiently synthesized using 3,5-dihydroxybenzaldehyde as an aldehyde focal point functionalized unit by adding a generation to the existing dendron or direct oxidation of Fr$\acute{e}$chet-type dendritic benzyl alcohols. These dendritic benzaldehydes were applied for the construction of dendrimers containing secondary amines as connectors via Staudinger/aza-Wittig Reactions with ${\alpha}$,${\alpha}'$,-diazidop-xylene core.