IL -1${\beta}$ Expression of Cefodizime on Dendritic cell and Macrophage

  • Joo, Seong-Soo (Division of Immunology College of Pharmacy, Chung Ang University) ;
  • Kwon, Hee-Seung (Division of Immunology College of Pharmacy, Chung Ang University) ;
  • Lee, Do-Ik (Division of Immunology College of Pharmacy, Chung Ang University)
  • Published : 2002.10.01

Abstract

According to recent studies. cefodizime. a third generation cephalosporin antibiotic agent. may potentially have the capability of stimulating chemotactic activity of neutrophils and monocytes as well as the strong immuno-modulator. We have studied to see if cefodizime can be a potential substance inducing an Immunological activities on immune cells. such as dendritic cells and macrophages. In experimental process. dendritic cell and macrophage were taken from mice and mixed with 10${\mu}\ell$/$m\ell$. 50$${\mu}\ell$/$m\ell$, 100${\mu}\ell$/$m\ell$.cefodizime and 1$${\mu}\ell$/$m\ell$ IFN-${\gamma} 10U/$m\ell$+LPS. (omitted)

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