• Journal of Korean Ophthalmic Optics Society
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• v.20 no.4
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• pp.491-499
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• 2015

Purpose: This study was to examine how decline of visual function affects visual perception by assessing visual perception after improving visual function through visual training, and observing the change in the cognitive ability of visual perception. Methods: This study analyzes the visual perceptual evaluation (TVPS_R) of 23 children below age 13($8.75{\pm}1.66$) who have visual abnormalities, and improves visual function after conducting vision training (vision therapy) of the children. Results: Convergence increased from average $3.39{\pm}2.52{\Delta}$ (prism) to $13.87{\pm}6.04{\Delta}$ in the measurement of long-distance disparate points, and from average $5.48{\pm}3.42{\Delta}$ to $18.43{\pm}7.58{\Delta}$ in the measurement of short-distance disparate points. Short-distance diplopia points increased from $25.87{\pm}7.33cm$ to $7.48{\pm}2.87cm$, and as for accommodative insufficiency, short-distance blur points increased from $19.57{\pm}7.16cm$ to $7.09{\pm}1.88cm$. In the visual perceptual evaluation performed before and after improving visual function, 6 items except visual memory showed statistically significant improvement. By order of significant improvement, response gap was highest with $17.74{\pm}16.94$(p=0.000) in visual closure, followed by $15.65{\pm}17.11$(p=0.000) in visual sequential-memory, $13.65{\pm}16.63$(p=0.001) in visual figure-ground, $12.74{\pm}18.41$(p=0.003) in visual form-constancy, $6.48{\pm}10.07$ (p=0.005) in visual discrimination, and $4.17{\pm}9.33$(p=0.043) in visual spatial-relationship. In the visual perception quotient that added up these scores, the response gap was $15.22{\pm}8.66$(p=0.000), showing a more significant result. Conclusions: Vision training enables efficient visual processing and improves visual perceptual ability. It was confirmed that improvement of visual function through visual training not only improves abnormal visual function but also affects visual perception of children such as learning, perception and recognition.

• Communications of the Korean Mathematical Society
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• v.33 no.3
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• pp.1025-1037
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• 2018

We consider an ill-posed problem for the heat equation $u_{xx}=u_t$ in the quarter plane {x > 0, t > 0}. We propose a new method to compute the heat flux $h(t)=u_x(1,t)$ from the boundary temperature g(t) = u(1, t). The operator $g{\mapsto}h=Hg$ is unbounded in $L^2({\mathbb{R}})$, so we approximate h(t) by $h_{\delta}(t)=u_x(1+{\delta},\;t)$, ${\delta}{\rightarrow}0$. When noise is present, the data is $g_{\epsilon}$ leading to a corresponding heat $h_{{\delta},{\epsilon}}$. We obtain an estimate of the error ${\parallel}h-h_{{\delta},{\epsilon}}{\parallel}$, as well as the error when $h_{{\delta},{\epsilon}}$ is approximated by the trapezoidal rule. With an a priori choice rule ${\delta}={\delta}({\epsilon})$ and ${\tau}={\tau}({\epsilon})$, the step size of the trapezoidal rule, the main theorem gives the error of the heat flux as a function of noise level ${\epsilon}$. Numerical examples show that the proposed method is effective and stable.

• Journal of the Korean Society of Safety
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• v.6 no.4
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• pp.81-87
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• 1991

We propose the crack growth rate equation which will model fatigue crack growth rate behavior such that constant stress amplitude fatigue crack growth behavior can be predicted. Constant stress amplitude fatigue tests are conducted for four materials under three stress ratios of R＝0.2, R＝0.4 and R＝0.6. Materials which have different mechanical properties i.e. stainless steel, low carbon steel, medium carbon steel and aluminum alloy are used. Through constant stress amplitude fatigue test by using unloading elastic compliance method, it is confirmed that crack closure is a close relationship with fatigue crack propagation. We describe simply fatigue crack propagation behavior as a function of the effective stress intensity factor range ($\Delta$ $K_{eff}$＝U .$\Delta$K) for all three regions (threshold region, stable region). The fatigue crack growth rate equation is given by da / dN＝A($\Delta$ $K_{eff}$­$\Delta$ $K_{o}$ )$^{m}$ / ($\Delta$ $K_{eff}$­$\Delta$K) Where, A and m are material constants, and $\Delta$ $K_{o}$ is stress intensity factor range at low $\Delta$K region. $K_{cf}$ is critical fatigue stress intensity factor.actor.

• Journal of the Chungcheong Mathematical Society
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• v.17 no.2
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• pp.163-167
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• 2004

In this paper, we obtain some coefficient estimates of harmonic, orientation-preserving, univalent mappings defined on ${\Delta}$ = {z : |z| > 1}.

• Proceedings of the KIEE Conference
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• 1999.07d
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• pp.1563-1565
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• 1999

Linear and nonliear complex permittivities have been measured for amorphous copolymers of vinylidene cyanide (VDCN) with vinyl acetate (VAc), vinyl propionate (VPr), vinyl benzoate (VBz), styrene (St) and methyl methacrylate (MMA). It is found that the third order permittivity ${\varepsilon}_3$ depends upon frequency according to a function ${\Delta}_{{\varepsilon}_3}/(1+i{\omega}{\tau}_^3)$ while the linear permittivity obeys a Debye function ${\Delta}_{{\varepsilon}_1}/(1+i{\omega}{\tau}_1)$. Experimental results are well fitted by the above predicted functions except at low frequencies where dc conduction dominates. The ${\tau}_1$ and ${\tau}_3$ are nearly equal, and depend upon temperature according to a WLF form. The relaxation strength ${\Delta}_{{\varepsilon}_1}$ depends upon comonomers ranging from $130_{{\varepsilon}_0}$(VAc) to $20{{\varepsilon}_0}$(MMA). The ${\Delta}_{{\varepsilon}_3}$ is negative and depends more strongly upon comonomers. Combined knowledge about linear and nonlinear permittivities predicts very large correlation factors which indicates strongly cooperative dipolar motions in those amorphous copolymers.

• Molecules and Cells
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• v.19 no.1
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• pp.23-30
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• 2005

Spinocerebellar ataxia type 1 (SCA1) is an autosomal-dominant neurodegenerative disorder caused by expansion of the polyglutamine tract in the SCA1 gene product, ataxin-1. Using d2EGFP, a short-lived enhanced green fluorescent protein, we investigated whether polyglutamine-expanded ataxin-1 affects the function of the proteasome, a cellular multicatalytic protease that degrades most misfolded proteins and regulatory proteins. In Western blot analysis and immunofluorescence experiments, d2EGFP was less degraded in HEK 293T cells transfected with ataxin-1(82Q) than in cells transfected with lacZ or empty vector controls. To test whether the stability of the d2EGFP protein was due to aggregation of ataxin-1, we constructed a plasmid carrying $ataxin-1-{\Delta}114$, lacking the self-association region (SAR), and examined degradation of the d2EGFP. Both the level of $ataxin-1-{\Delta}114$ aggregates and the amount of d2EGFP were drastically reduced in cells containing $ataxin-1-{\Delta}114$. Furthermore, d2EGFP localization experiments showed that polyglutamine-expanded ataxin-1 inhibited the general function of the proteasome activity. Taken together, these results demonstrate that polyglutamine-expanded ataxin-1 decreases the activity of the proteasome, implying that a disturbance in the ubiquitin-proteasome pathway is directly involved in the development of spinocerebellar ataxia type1.

• Bulletin of the Korean Mathematical Society
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• v.50 no.5
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• pp.1693-1710
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• 2013

In this paper, we consider the biharmonic elliptic systems of the form $$\{{\Delta}^2u=F_u(u,v)+{\lambda}{\mid}u{\mid}^{q-2}u,\;x{\in}{\Omega},\\{\Delta}^2v=F_v(u,v)+{\delta}{\mid}v{\mid}^{q-2}v,\;x{\in}{\Omega},\\u=\frac{{\partial}u}{{\partial}n}=0,\; v=\frac{{\partial}v}{{\partial}n}=0,\;x{\in}{\partial}{\Omega},$$, where ${\Omega}{\subset}\mathbb{R}^N$ is a bounded domain with smooth boundary ${\partial}{\Omega}$, ${\Delta}^2$ is the biharmonic operator, $N{\geq}5$, $2{\leq}q$ < $2^*$, $2^*=\frac{2N}{N-4}$ denotes the critical Sobolev exponent, $F{\in}C^1(\mathbb{R}^2,\mathbb{R}^+)$ is homogeneous function of degree $2^*$. By using the variational methods and the Ljusternik-Schnirelmann theory, we obtain multiplicity result of nontrivial solutions under certain hypotheses on ${\lambda}$ and ${\delta}$.

• Kyungpook Mathematical Journal
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• v.50 no.3
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• pp.389-397
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• 2010

In this paper we introduce the new generalized difference sequence space $\ell_\infty$($\Delta_v^n$, M,p,q,s), $\bar{c}$($\Delta_v^n$,M,p,q,s), $\bar{c_0}$($\Delta_v^n$,M,p,q,s), m($\Delta_v^n$,M,p,q,s) and $m_0$($\Delta_v^n$,M,p,q,s) defined over a seminormed sequence space (X,q). We study some of it properties, like completeness, solidity, symmetricity etc. We obtain some relations between these spaces as well as prove some inclusion result.

• Proceedings of the IEEK Conference
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• 2006.06a
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• pp.627-628
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• 2006

A low-voltage switched-capacitor $2^{nd}$-order $\Sigma\Delta$ modulator using full feed-forward is introduced. It has two advantages: the unity signal transfer function and reduced signal swings inside the $\Sigma\Delta$ loop. These features greatly relax the DC gain and output swing requirements for Op-Amp in the low-voltage $\Sigma\Delta$ modulator. Implemented by a 0.18-${\mu}m$ CMOS technology, the $\Sigma\Delta$ modulator satisfies performance requirements for WCDMA and CDMA2000 standards.

• Journal of Microbiology and Biotechnology
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• v.27 no.4
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• pp.775-784
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• 2017

A neutral xylanase (CcXyn) was identified from Coprinus cinereus. It has a single GH10 catalytic domain with a basic amino acid-rich extension (PVRRK) at the C-terminus. In this study, the wild-type (CcXyn) and C-terminus-truncated xylanase ($CcXyn-{\Delta}5C$) were heterologously expressed in Pichia pastoris and their characteristics were comparatively analyzed with aims to examine the effect of this extension on the enzyme function. The circular dichorism analysis indicated that both enzymes in general had a similar structure, but $CcXyn-{\Delta}5C$ contained less ${\alpha}-helices$ (42.9%) and more random coil contents (35.5%) than CcXyn (47.0% and 32.8%, respectively). Both enzymes had the same pH (7.0) and temperature ($45^{\circ}C$) optima, and similar substrate specificity on different xylans. They all hydrolyzed beechwood xylan primarily to xylobiose and xylotriose. The amounts of xylobiose and xylotriose accounted for 91.5% and 92.2% (w/w) of total xylooligosaccharides (XOS) generated from beechwood by CcXyn and $CcXyn-{\Delta}5C$, respectively. However, truncation of the C-terminal 5-amino-acids extension significantly improved the thermostability, SDS resistance, and pH stability at pH 6.0-9.0. Furthermore, $CcXyn-{\Delta}5C$ exhibited a much lower $K_m$ value than CcXyn (0.27 mg/ml vs 0.83 mg/ml), and therefore, the catalytic efficiency of $CcXyn-{\Delta}5C$ was 2.4-times higher than that of CcXyn. These properties make $CcXyn-{\Delta}5C$ a good model for the structure-function study of $({\alpha}/{\beta})_8$-barrel-folded enzymes and a promising candidate for various applications, especially in the detergent industry and XOS production.