• 한국식물병리학회:학술대회논문집
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• 한국식물병리학회 2002년도 총회 및 추계학술발표회
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• pp.72.1-72
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• 2002

• BMB Reports
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• 제41권2호
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• pp.93-101
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• 2008

The major cell wall components of bacteria are lipopolysaccharide, peptidoglycan, and teichoic acid. These molecules are known to trigger strong innate immune responses in the host. The molecular mechanisms by which the host recognizes the peptidoglycan of Gram-positive bacteria and amplifies this peptidoglycan recognition signals to mount an immune response remain largely unclear. Recent, elegant genetic and biochemical studies are revealing details of the molecular recognition mechanism and the signalling pathways triggered by bacterial peptidoglycan. Here we review recent progress in elucidating the molecular details of peptidoglycan recognition and its signalling pathways in insects. We also attempt to evaluate the importance of this issue for understanding innate immunity.

• Steel and Composite Structures
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• 제23권1호
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• pp.107-114
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• 2017

Design of stepwise foam claddings subjected to air-blast is performed based on random Voronoialgorithm. FE models are constructed using the random Voronoialgorithm, and numerical analysis is carried out to simulate deformation mode and energy absorption of the cladding by the ABAQUS/Explicit software. The FE model is validated by test result, and good agreement is achieved. The deformation patterns are presented to give an insight into the influences of distribution on deformation mechanisms. The energy absorbed by the stepwise foam cladding is examined, and the parameter effects, including layer number, gradient, and blast loading, are discussed. Results indicate that the energy absorption capacity increases with the number of layer, gradient degree, and blast pressure increasing.

• The Plant Pathology Journal
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• 제20권1호
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• pp.22-29
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• 2004

Many important horticultural and field crops are susceptible to virus infections or may possess a degree of resistance to some viruses, but become infected by others. Plant viruses enter cells through the presence of wounds, and replicate intracellularly small genomes that encode genes required for replication, cell-to-cell movement and encapsidation. There are numerous evidences from specific virus-host interactions to require the involvement of host factors and steps during viral replication cycle. However, viruses should deal with host defense responses either by general or specific mechanisms, targeting viral components or genome itself. On the other hand, the host plants have also adapted to defend themselves against viral attack by operating different lines of resistance responses. The defense-related interactions provide new insights into the complex molecular strategies for hosts for defense and counter-defense employed by viruses.

• 한국환경농학회지
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• 제12권3호
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• pp.264-280
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• 1993

The environmental pollutions were a serious problem in Korea recently. So many researcher have studied the effect of environmental pollution on plants and agro-ecosystem, but the basic mechanisms of environmental stresses were various. One of the important mechanisms was oxidative stress caused by active toxic oxygen. The toxic oxygen was generated by several stresses, abnormal temperature, many xenobiotics, air pollutants, water stress, fugal toxin, etc. In the species of toxic oxygen which is primary inducer of oxidative stresses, superoxide, hydrogen peroxide, hydroxyl radical and singlet oxygen were representative species. The scavenging systems were divided into two groups. One was nonenzymatic system and the other enzymatic system. Antioxidants such as glutathione, ascorbic acid, and carotenoid, have the primary function in defense mechanisms. Enzymatic system divided into two groups; First, direct interaction with toxic oxygen(eg. superoxide dismutase). Second, participation in redox reaction to maintain the active antioxidant levels(eg. glutathione reductase, ascorbate peroxidase, etc.).

• Advances in Traditional Medicine
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• 제8권1호
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• pp.1-16
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• 2008

Immunity is responsible for the defense mechanism of the body but in case of autoimmune diseases, its role gets diverted. Like so many other diseases, asthma is also considered as one of the most common autoimmune diseases to be occurring in community. Asthma is defined as a chronic inflammatory airway disease that is characterized by airway hyper reactivity and mucus hypersecretion that result in intermittent airway obstruction. The incidence of allergic asthma has almost doubled in the past two decades. Although, precise causative mechanism of asthma is unknown, but several mechanisms have been proposed that is immunological, pharmacological and genetic mechanisms, and airway and neurogenic inflammation. The inflammatory process observed in the asthmatic patients is the final result of a complex network of interactions between various immunological cell lineages, its mediators and secreted substances. Thus, among the mechanisms proposed, the immunological one plays a key role. Through this article, we have tried to provide some insight into immunological mechanisms in pathogenesis of asthma.

• 정보처리학회논문지:컴퓨터 및 통신 시스템
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• 제9권5호
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• pp.101-106
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• 2020

컴퓨터가 보급된 이래로 정보보안을 달성하기 위해 많은 노력이 이루어졌다. 그중 메모리 보호 기법에 대한 연구가 가장 많이 이루어졌지만, 컴퓨터의 성능 향상으로 기존 메모리 보호 기법의 문제들이 발견되었고 부채널 공격의 등장으로 새로운 방어기법이 필요하게 되었다. 본 논문에서는 JMP+RAND 기법을 이용해 페이지(Page)마다 5-8byte의 난수를 삽입하여 메모리 공유 기반 부채널 공격을 방어하고 기존 메모리 보호 기법도 보완하는 방법을 제안한다. 기존 부채널 공격들의 방어기법과 달리 JMP+RAND 기법은 정적 바이너리 재작성 기법(Static binary rewriting)과 연속된 jmp 명령어, 난수 값을 이용해 사전에 부채널 공격을 방어한다. 우리는 메모리 공유 기반 부채널 공격이 JMP+RAND 기법이 적용된 바이너리를 공격하는 데 걸리는 시간을 정량적으로 계산하였고 현실적인 시간 내에 공격할 수 없다는 것을 보여주었다. 최근 아키텍처는 분기 예측(Branch prediction)을 이용해 jmp 명령어의 분기처리가 매우 빠르고 정확하므로 JMP+RAND 기법의 오버헤드가 매우 낮다. 특히 특정 프로그램에만 난수 삽입이 가능하므로 클라우드 컴퓨팅 환경에서 메모리 중복제거 기능과 함께 사용하면 높은 효율성을 보일 수 있을 것으로 기대한다.

• Mycobiology
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• 제29권1호
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• pp.19-26
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• 2001

Defense mechanisms against anthracnose disease caused by Colletotrichum orbiculare on the leaf surface of cucumber plants after pre-treatment with plant growth promoting rhizobacteria(PGPR), amino salicylic acid(ASA) or C. orbiculare were compared using a fluorescence microscope. Induced systemic resistance was mediated by the pre-inoculation in the root system with PGPR strain Bacillus amylolquefaciens EXTN-1 that showed direct antifungal activity to C. gloeosporioides and C. orbiculare. Also, systemic acquired resistance was triggered by the pre-treatments on the bottom leaves with amino salicylic acid or conidial suspension of C. orbiculare. The protection values on the leaves expressing SAR were higher compared to those expressing ISR. After pre-inoculation with PGPR strains no change of the plants was found in phenotype, while necrosis or hypersensitive reaction(HR) was observed on the leaves of plants pre-treated with ASA or the pathogen. After challenge inoculation, inhibition of fungal growth was observed on the leaves expressing both ISR and SAR. HR was frequently observed at the penetration sites of both resistance-expressing leaves. Appressorium formation was dramatically reduced on the leaves of plants pre-treated with ASA, whereas EXTN-1 did not suppress the appressorium formation. ASA also more strongly inhibited the conidial germination than EXTN-1. Conversely, EXTN-1 significantly increased the frequency of callose formation at the penetration sites, but ASA did not. The defense mechanisms induced by C. orbiculare were similar to those by ASA. Based on these results it is suggested that resistance mechanisms on the leaf surface was different between on the cucumber leaves expressing ISR and SAR, resulting in the different protection values.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제10권9호
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• pp.4529-4548
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• 2016

DDoS attacks have had a devastating effect on the Internet, which can cause millions of dollars of damage within hours or even minutes. In this paper we propose a practical dynamic defense approach that overcomes the shortage of static defense mechanisms. Our approach employs a group of SDN-based proxy switches to relay data flow between users and servers. By substituting backup proxy switches for attacked ones and reassigning suspect users onto the new proxy switches, innocent users are isolated and saved from malicious attackers through a sequence of remapping process. In order to improve the speed of attacker segregation, we have designed and implemented an efficient greedy algorithm which has been demonstrated to have little influence on legitimate traffic. Simulations, which were then performed with the open source controller Ryu, show that our approach is effective in alleviating DDoS attacks and quarantining the attackers by numerable remapping process. The simulations also demonstrate that our dynamic defense imposes little effect on legitimate users, and the overhead introduced by remapping procedure is acceptable.

• The Plant Pathology Journal
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• 제37권5호
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• pp.415-427
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• 2021

A plethora of compounds stimulate protective mechanisms in plants against microbial pathogens and abiotic stresses. Some defense activators are synthetic compounds and trigger responses only in certain protective pathways, such as activation of defenses under regulation by the plant regulator, salicylic acid (SA). This review discusses the potential of naturally occurring plant metabolites as primers for defense responses in the plant. The production of the metabolites, hexanoic acid and melatonin, in plants means they are consumed when plants are eaten as foods. Both metabolites prime stronger and more rapid activation of plant defense upon subsequent stress. Because these metabolites trigger protective measures in the plant they can be considered as "vaccines" to promote plant vigor. Hexanoic acid and melatonin instigate systemic changes in plant metabolism associated with both of the major defense pathways, those regulated by SA- and jasmonic acid (JA). These two pathways are well studied because of their induction by different microbial triggers: necrosis-causing microbial pathogens induce the SA pathway whereas colonization by beneficial microbes stimulates the JA pathway. The plant's responses to the two metabolites, however, are not identical with a major difference being a characterized growth response with melatonin but not hexanoic acid. As primers for plant defense, hexanoic acid and melatonin have the potential to be successfully integrated into vaccination-like strategies to protect plants against diseases and abiotic stresses that do not involve man-made chemicals.