• Journal of Chest Surgery
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• v.56 no.2
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• pp.99-107
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• 2023

Background: The neutrophil-to-lymphocyte ratio (NLR) has been suggested as a novel predictive marker of cardiovascular disease. However, its prognostic role in patients under-going coronary artery bypass grafting (CABG) is unclear. This study aimed to determine the association between the preoperative NLR and early mortality in patients undergoing CABG. Methods: Cardiac surgery was performed in 2,504 patients at Seoul St. Mary's Hospital from January 2010 to December 2021. This study retrospectively reviewed 920 patients who underwent isolated CABG, excluding those for whom the preoperative NLR was unavailable. The primary endpoints were the 30- and 90-day mortality after isolated CABG. Risk factor analysis was performed using logistic regression analysis. Based on the optimal cut-off value of preoperative NLR on the receiver operating characteristic curve, high and low NLR groups were compared. Results: The 30- and 90-day mortality rates were 3.8% (n=35) and 7.0% (n=64), respectively. In the multivariable analysis, preoperative NLR was significantly associated with 30-day mortality (odds ratio [OR], 1.28; 95% confidence interval [CI], 1.17-1.39; p<0.001) and 90-day mortality (OR, 1.17; 95% CI, 1.07-1.28; p<0.001). The optimal cut-off value of the preoperative NLR was 3.4. Compared to the low NLR group (<3.4), the high NLR group (≥3.4) showed higher 30- and 90-day mortality rates (1.4% vs. 12.1%, p<0.001; 2.8% vs. 21.3%, p<0.001, respectively). Conclusion: Preoperative NLR was strongly associated with early mortality after isolated CABG, especially in patients with a high preoperative NLR (≥3.4). Further studies with larger cohorts are necessary to validate these results.

• Fisheries and Aquatic Sciences
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• v.16 no.4
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• pp.237-242
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• 2013

We investigated the antioxidant and angiotensin I converting enzyme (ACE) inhibitory activities of red snow crab Chionoecetes japonicas shell (RSCS) hydrolysate by enzymatic hydrolysis and its molecular weight cut-off fractions. The RSCS hydrolysate was fractionated through two ultrafiltration membranes of 3 and 10 kDa cut-offs. Three fractions (<3 kDa, 3-10 kDa, and >10 kDa) were evaluated for total amino acid composition, antioxidant activities using 2'-azino-bis[3-ethylbenzthiazoline-6-sulfonic acid] ($ABTS^+$) radical scavenging and superoxide dismutase (SOD)-like activities and reducing power assays, and ACE inhibitory activity using Hou's method. Although all fractions showed activity, the <3 kDa fraction of RSCS hydrolysate exhibited the greatest $ABTS^+$ radical scavenging, SOD-like and ACE inhibitory activities. However, these fractions exhibited low reducing power. These results suggest that the low-molecular-weight enzymatic hydrolysate of RSCS could be used as a functional ingredient to control oxidative stress and ACE activity.

• Transactions of the Korean Society of Automotive Engineers
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• v.12 no.2
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• pp.190-196
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• 2004

ACR(All Clear Reflector), also widely referred to as FFR(Free Form Reflector), were designed in general and intelligent ways using a NUDBS surface for the mathematical modelling of the reflector shape and artificial intelligence as the optimum design algorithm. An ACR, which consists of a continuous surface reflector and clear outer lens, offers styling advantages and provides a high quality light performance. The clear outer lens of an ACR remains efficient even with a highly inclined shape, as in the design of a sports car, as well as the complete clearness of the reflector surface eliminates the nuisance of stray light caused by the steps between adjacent segments of multi-faced reflectors. The application of an ACR to low beam lamp was so sucessful to obtain the sharp cut-off with the lens-free single-surfaced-smooth reflector. The design technique of ACR was tested with all types of lamps, including low beams, high beams, and fog lamps.

• Proceedings of the Korea Electromagnetic Engineering Society Conference
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• 2005.11a
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• pp.63-68
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• 2005

In this paper, Coplanar Waveguide(CPW) low-pass filter with the spurious-reduced is designed by using Defected Ground Structures(DGS). Two different LPF unit cells and DGS pattern are combined to reduce the spurious. In comparison to a conventional step impedance LPF, the size of proposed LPF as 17.2mm*6.8mm is several times smaller. The simulation and measurements confirm that spurious characteristics is presented less than -30dB($S_{21}$) to three times cut off frequency.

• Journal of Genetic Medicine
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• v.10 no.1
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• pp.52-56
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• 2013

Mosaic trisomy 14 syndrome is a well-known but unusual chromosomal abnormality with a distinct and recognizable phenotype. Array comparative genomic hybridization (CGH) analysis has recently become a widely used method for detecting DNA copy number changes, in place of traditional karyotype analysis. However, the array CGH shows a limitation for detecting the low-level mosaicism. Here, we report the detailed clinical and cytogenetic findings of patient with low-frequency mosaic trisomy 14, initially considered normal based on usual cut-off levels of array CGH, but confirmed by G-banding karyotyping. Our patient had global developmental delay, short stature, congenital heart disease, craniofacial dysmorphic features, and dark skin patches over her whole body. Estimated mosaicism proportion was 23.3% by G-banding karyotyping and 18.0% by array CGH.

• Journal of the Korean Institute of Telematics and Electronics A
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• v.32A no.3
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• pp.118-123
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• 1995

We have successfully fabricated a super low noise pseudomorphic HEMT(PHEMT) device with AlGaAs/InGaAs/GaAs sturcture by using improved T-Gate which have increased a large gaet cross-sectional area about two times in comparision with those of conventional T-gate processes. The PHEMSTs with 0.15$\mu$m-long and 140$\mu$m-wide gates have eshibited a super low noise characteristics, the noise figure of 0.45dB with associated gain of 10.87dB at 12GHz. The cut-off rewuqncy of the device is 94gHz with a transconductance of 418mS/mm.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2002.10a
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• pp.235-240
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• 2002

In micro-EBM, it is well blown that RC circuit is suitable for discharge circuit because of its low pulse width and relatively high peak current. To increase machining speed without changing unit discharge energy, charge resistance should be decreased. But, if very low, continuous (or normal) arc discharge occurs, then increases electrode wear and reduces machining speed remarkably. In this paper, RC circuit with transistor is used to micro-EDM. Experimental results show that RC circuit with transistor can cut off continuous (or normal) arc discharge effectively if duty factor and switching period of transistor are set up optimally. Through experiments with varying charge resistance, it can be known that RC circuit with transistor has about two times faster machining speed than that of RC circuit. Especially, it has prominent rise-effect of machining speed in low unit discharge energy, so that a high-quality and high-speed micro-EDM can be realized through RC circuit with transistor.

• Proceedings of the KSR Conference
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• 2008.06a
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• pp.316-320
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• 2008

This paper described the design and fabrication of a series arc detection module to monitor electrical insulation in low-voltage system. The module consists of a passive high-pass filter with a low cut-off frequency of 3 kHz to attenuate power frequency voltage by 80 dB and an active band-pass filter with a frequency of 4 kHz to detect series arc signals only. For the application experiment, we simulated series arcing phenomena on various loads such as incandescent lamp controlled by dimmer and inverter fed induction motors by an arc generator specified in UL1699. From the experimental results, we could detect series arc signals without an influence of noises.

• Journal of the Korea Society for Simulation
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• v.10 no.4
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• pp.21-30
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• 2001

In this paper, EMI measurement, the STGU simulation being conducted, filter design, its characteristics, and its implementation to the PCB, and finally test results are discussed. When the low pass filter was implemented within the STGU, the power of EMI decreased more than 20dBm. Finally, when TE and MTIE, two important quality measure in synchronous reference clock, was assessed, ITU-T G813 requirement was satisfied. EMI(Electromagnetic Interface) is a measure of electomagnetic radiation from equipment in the range of 10KHz to 3GHz, and can cause unexpected reactions of electronics/electrical equipment. In this study, for safe and stable communication operation, a STGU (System Timing Generation Unit), which is a 2.5G SDH System and a major EMI source, was employed to simulate electromagnetic interface. Using Open-Site test, the power of fundamental frequency of EMI of interest and its harmonics were measured. Also, a low pass filter at cut-off frequency of 2GHz was specifically designed for this study to minimize the effect of EMI between electronic components.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.53 no.8
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• pp.432-437
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• 2004

Since the characteristic frequency is decreased in proportion to the fault distance, the characteristic frequency component may be insufficiently eliminated by a low-pass filter on a long transmission line. In order to set a standard for the cut-off frequency of the low-pass filter, this paper proposes a method for obtaining the characteristic frequencies due to line faults. The application results of the proposed method are presented for line to ground (LG) faults and line to line (LL) faults on a 345 kV 200 km overhead transmission line. The EMTP is used to generate fault signals under different fault locations and fault inception angles. By comparison between the characteristic frequencies obtained from the proposed method and the EMTP simulation, it is shown that the proposed method accurately obtains the characteristic frequency.