• Communications for Statistical Applications and Methods
• /
• 제19권6호
• /
• pp.899-904
• /
• 2012

High-dimensional categorical data models with small sample sizes have not been used extensively in genomic sequences that involve count (or discrete) or purely qualitative responses. A basic task is to identify differentially expressed genes (or positions) among a number of genes. It requires an appropriate test statistics and a corresponding multiple testing procedure so that a multivariate analysis of variance should not be feasible. A family wise error rate(FWER) is not appropriate to test thousands of genes simultaneously in a multiple testing procedure. False discovery rate(FDR) is better than FWER in multiple testing problems. The data from the 2002-2003 SARS epidemic shows that a conventional FDR procedure and a proposed test statistic based on a pseudo-marginal approach with Hamming distance performs better.

• 소음진동
• /
• 제9권5호
• /
• pp.966-974
• /
• 1999

This paper introduces modeling and its modal analysis procedure for exact and closed form solution of in-plane vibrations of general Timoshenko frame structures using exact dynamic element method(EDEM). The derivation procedure of the exact system dynamic matrices for Timoshenko beam frames is described. A new modal analysis procedure is also proposed since the conventional modal analysis schemes are not adequate for the proposed, exact system dynamic matrix. The proposed method provides exact modal parameters as well as all kinds of closed form solutions for general frame structures. Two numerical examples are presented for validating and illustrating the proposed method. The numerical study proves that the proposed method is useful for dynamic analysis of frame structures.

• 대한조선학회지
• /
• 제21권4호
• /
• pp.40-48
• /
• 1984

The computer program DASH(Direct Analysis of Ship's Hull), based on the direct calculating procedure as proposed at the 4th ISSC(1970), was developed. The DASH program is designed by the following calculation procedure: 1) Derivation of the design wave loads through the ship motion analysis based on the strip theory. 2) Stress analysis of the hull girder based on the 7-degree of the freedom beam theory including the warping torsion effect. 3) Long-term prediction of the stresses based on the statistical approach using sea-spectrums and ocean wave data in the ship's route. An example calculation was performed for the purpose of a demonstration of the present approach on the 16,200 DWT Oil Tanker. The results are discussed and compared with the conventional method.

• Journal of Mechanical Science and Technology
• /
• 제15권11호
• /
• pp.1507-1516
• /
• 2001

An analytical method is presented for evaluation of the steady state periodic behavior of nonlinear structural systems. This method is based on the substructure synthesis formulation and a harmonic balance procedure, which is applied to the analysis of nonlinear responses. A complex nonlinear system is divided into substructures, of which equations are approximately transformed to modal coordinates including nonlinear term under the reasonable procedure. Then, the equations are synthesized into the overall system and the nonlinear solution for the system is obtained. Based on the harmonic balance method, the proposed procedure reduces the size of large degrees-of-freedom problem in the solving nonlinear equations. Feasibility and advantages of the proposed method are illustrated using the study of the nonlinear rotating machine system as a large mechanical structure system. Results obtained are reported to be an efficient approach with respect to nonlinear response prediction when compared with other conventional methods.

• 대한화학회지
• /
• 제60권4호
• /
• pp.245-250
• /
• 2016

An improved protocol on the synthesis of thiazolo[3,2-a]pyrimidine-6-carboxylate derivatives are reported. Previously, the thiazolo[3,2-a]pyrimidine-6-carboxylate derivatives were prepared in a two-step procedure. Under the improved procedure, the thiazolo[3,2-a]pyrimidine-6-carboxylate derivatives was readily prepared in a one-step reaction. This procedure was found to be more efficient than the previous protocol and also compared to the ultrasound bath and conventional heating methods in terms of yield and reaction time.

• Geomechanics and Engineering
• /
• 제7권2호
• /
• pp.149-164
• /
• 2014

One of the most advanced classes of techniques for ground response analysis is based on the use of Transfer Functions. They represent the ratio of Fourier spectrum of amplitude motion at the free surface to the corresponding spectrum of the bedrock motion and they are applied in frequency domain usually by FFT method. However, Fourier spectrum only shows the dominant frequency in each time step and is unable to represent all frequency contents in every time step and this drawback leads to inaccurate results. In this research, this process is optimized by decomposing the input motion into different frequency sub-bands using Wavelet Multi-level Decomposition. Each component is then processed with transfer Function relating to the corresponding component frequency. Taking inverse FFT from all components, the ground motion can be recovered by summing up the results. The nonlinear behavior is approximated using an iterative procedure with nonlinear soil properties. The results of this procedure show better accuracy with respect to field observations than does the Conventional method. The proposed method can also be applied to other engineering disciplines with similar procedure.

• Journal of Minimally Invasive Surgery
• /
• 제21권4호
• /
• pp.148-153
• /
• 2018

Purpose: Single incision laparoscopic appendectomy (SILA) is a widely used surgical procedure for treatment of appendicitis with better cosmesis. However, many surgeons generally tend to choose conventional multiport laparoscopic appendectomy regarding with complicated appendicitis. The aim of this study is to demonstrate the safety and feasibility of SILA for treatment of complicated appendicitis by comparison with 3-ports conventional laparoscopic appendectomy (CLA). Methods: Retrospective chart review of patients diagnosed appendicitis at single hospital during January 2015 to May 2017 collected 500 patients. Among 134 patients with complicated appendicitis, we compared outcomes for 29 patients who got SILA and 105 patients who got CLA. Results: 179 and 321 patients were treated by SILA and CLA, respectively. 134 (26.8%) patients were treated for complicated appendicitis, 29 patients by SILA and 105 patients by CLA, respectively. There was no case converted to open or added additional trocar in both groups. There were no differences in demographics with regard to age, sex, body mass index (BMI), and American society of anesthesiologists (ASA) scores. There was no difference in mean operating time ($58.97{\pm}18.53$ (SILA) vs. $57.57{\pm}21.48$ (CLA), p=0.751). The drain insertion rate (6.9% vs 37.1%, p=0.001) and the length of hospital stay ($2.76{\pm}1.41$ vs. $3.97{\pm}2.97$, p=0.035) were lower in SILA group with significance. There was no significant difference in the rate of surgical site infection (6.9% vs. 6.7%, p=1.000). Conclusion: This study demonstrates that SILA is a feasible and safe procedure for treatment of complicated appendicitis.

• 한국지하수토양환경학회:학술대회논문집
• /
• 한국지하수토양환경학회 2001년도 추계학술발표회
• /
• pp.184-187
• /
• 2001

This study presents procedure and analysis method for not well known slug interference tests. Results of the slug interference tests were compared with those of pumping and recovery tests and conventional slug tests.

• Industrial Engineering and Management Systems
• /
• 제12권4호
• /
• pp.368-379
• /
• 2013

Efficiency in work training is a perennial issue due to high-diversity low-volume production, particularly for manufacturers producing office machines which are manually assembled by workers. To reduce the training cost, parts used in training are usually reused; a trainer disassembles a product assembled by a worker in training. This paper proposes a training method that employs disassembly usually performed by a trainer. This method assigns both assembly and disassembly to a worker in training, in contrast to the conventional method. The effectiveness of the proposed method is experimentally discussed in terms of learning assembly motions and work procedure at each learning stage, namely, "undergoing learning," "immediately after learning," and "seven days after learning." The effectiveness of the training method is confirmed. The method improves the stability of work procedure recollection immediately after training. Furthermore, at seven days after training, it improves retention of the assembly motions and work procedure, and also promotes and maintains memory related to product structure.

• Nuclear Engineering and Technology
• /
• 제47권2호
• /
• pp.187-195
• /
• 2015

Human-induced initiating events, also called Category B actions in human reliability analysis, are operator actions that may lead directly to initiating events. Most conventional probabilistic safety analyses typically assume that the frequency of initiating events also includes the probability of human-induced initiating events. However, some regulatory documents require Category B actions to be specifically analyzed and quantified in probabilistic safety analysis. An explicit modeling of Category B actions could also potentially lead to important insights into human performance in terms of safety. However, there is no standard procedure to identify Category B actions. This paper describes a systematic procedure to identify Category B actions for low power and shutdown conditions. The procedure includes several steps to determine operator actions that may lead to initiating events in the low power and shutdown stages. These steps are the selection of initiating events, the selection of systems or components, the screening of unlikely operating actions, and the quantification of initiating events. The procedure also provides the detailed instruction for each step, such as operator's action, information required, screening rules, and the outputs. Finally, the applicability of the suggested approach is also investigated by application to a plant example.