• Title/Summary/Keyword: compounding

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Study on Electrochemical Property of Self-Assembled Viologen Monolayers Using Electrochemical Quartz Crystal Microbalance (EQCM) Method (EQCM법을 이용한 자기조립된 Viologen 단분자막의 전기화학적 특성 연구)

  • Lee, Dong-Yun;Park, Sang-Hyun;Park, Jae-Chul;Kwon, Young-Soo
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.55 no.3
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    • pp.107-110
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    • 2006
  • We fabricated the monolayers onto QCM by self-assembly using viologen, which has been widely used as electron acceptor. A gold electrode of the QCM was cleaned by piranha solution and prepared the ethanol-acetonitrile(1:1) solution with 2 m mol/l viololgen compounding of pure hi gas. We determined the time dependence to resonant frequency shift during self-assembly process and the electrochemical behavior of the self-assembled viologen monolayers by cyclic voltammetry. With increasing scan rate, the redox peak current of the viologen increased linearly. This was signified that the redox reaction was reversible. The EQCM measurements revealed the anions transfer during redox reactions, respectively. From the EQCM data, the well-defined shape peaks were nearly equal charges by cyclic voltammetry.

A Biopharmaceutical Study on the Absorptive Effect of Some Compounding Drugs(IV) -Effect on the Writhing Syndrome of Salicylamide Combined with Chlorpheniramine Maleate- (배합약물(配合藥物)의 흡수효과에 관(關)한 생물약제학적(生物藥劑學的) 연구(硏究)(IV) -Salicylamide에 Chlorpheniramine Maleate를 배합투여(配合投與)하였을 경우의 Writhing Syndrome에 미치는 영향(影響)에 관(關)하여-)

  • Chung, Ki-Hwa
    • Journal of Pharmaceutical Investigation
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    • v.5 no.4
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    • pp.32-37
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    • 1975
  • The intentional test of the clinical test on the mouse, which are orally administered salicylamide combined with chlorpheniramine maleate were made by writhing syndrome method of 0.7% acetic acid-saline solution and following effects were found. 1) The cross-over test of writhing syndrome method have intention in case of three days rest after the first examination. 2) The most active rate of salicylamide by administration combined with chlorpheniramine maleate is salicylamide 20mg/kg: chlorpheniramine maleate 20mg/kg (1:1) 3) The most active range of chlorpheniramine maleate used for assistant action of salicylamide is $15mg/kg{\sim}20mg/kg$

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The Effects of Proteolytic Enzyme on the Absorption and Excretion of Pyrazinamide (Proteolytic Enzyme이 Pyrazinamide의 흡수(吸收), 배설(排泄)에 미치는 영향(影響))

  • Lee, Jin-Hwan;Choi, Jun-Shik
    • Journal of Pharmaceutical Investigation
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    • v.5 no.4
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    • pp.24-31
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    • 1975
  • This paper attempts to investigate the effect of proteolytic enzyme on the absorption and excretion of pyrazinamide. The rat small intestinal absorption of pyrazinamide in the presence of proteolytic enzyme such as chymotrypsin and compounding enzyme (chymotrypsin and trypsin) are increasingly absorbed, but in the trypsin are similar to that of control. Blood levels of pyrazinamide after rabbit's duodenum injection are significantly enhenced to correspond to 112-120% by proteolytic enzymes concentration respectively, but both on the high concentration of chymotrypsin and the low concentration of trypsin are insignificantly enhenced. Proteolytic enzymes do not give the effect on clearance of pyrazinamide. Proteolytic enzymes give the effect on absorption of pyrazinamide, but do not give the effect on excretion of pyrazinamide.

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The Exponentiated Weibull-Geometric Distribution: Properties and Estimations

  • Chung, Younshik;Kang, Yongbeen
    • Communications for Statistical Applications and Methods
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    • v.21 no.2
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    • pp.147-160
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    • 2014
  • In this paper, we introduce the exponentiated Weibull-geometric (EWG) distribution which generalizes two-parameter exponentiated Weibull (EW) distribution introduced by Mudholkar et al. (1995). This proposed distribution is obtained by compounding the exponentiated Weibull with geometric distribution. We derive its cumulative distribution function (CDF), hazard function and the density of the order statistics and calculate expressions for its moments and the moments of the order statistics. The hazard function of the EWG distribution can be decreasing, increasing or bathtub-shaped among others. Also, we give expressions for the Renyi and Shannon entropies. The maximum likelihood estimation is obtained by using EM-algorithm (Dempster et al., 1977; McLachlan and Krishnan, 1997). We can obtain the Bayesian estimation by using Gibbs sampler with Metropolis-Hastings algorithm. Also, we give application with real data set to show the flexibility of the EWG distribution. Finally, summary and discussion are mentioned.

Introduction of Visceral Pain Model to Test of Visceral Nociception in the Rats (백서의 내장 신경통 연구를 위한 Visceral Pain Model(VPM)의 소개)

  • Lee, Chul-Woo
    • The Korean Journal of Pain
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    • v.8 no.1
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    • pp.25-30
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    • 1995
  • Anlgesic agents against visceral pain typically rely on a noxious chemical irritation of the peritoneum, e. g., acetic acid and phenylquinone writhing test. While useful, this type of assay depends upon an acute inflammation and the release of local alogens. Further, ethical and scientific constraints prevent repeated assessments in a single animal, thereby compounding the difficulty of assessing tolerance development to analgesic agents. To overcome these constraints, Colburn et al. developed a model for mechanical visceral pain model (VPM) based on a repeatable and reversible duodenal distention in the rat. A chronic indwelling intraduodenal balloon catheter is well tolerated and upon inflation produces a writhing response graded in proportion to distention. This response is inhibited by morphine in a dose dependent manner. We found that a model for visceral pain was thought to be a great value.

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Effects of Gums on Physical Properties of Oral Adhesive Tablets (Gum 종류에 따른 구강점막 부착정제의 물성 비교)

  • Chung, Bee-Hwan;Cha, Bong-Jin;Kwon, Jong-Won;Yang, Joong-Ik;Min, Shin-Hong
    • Journal of Pharmaceutical Investigation
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    • v.18 no.1
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    • pp.5-8
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    • 1988
  • Physical properties of oral adhesive tablets prepared with four kinds of gums for topical or systemic drug delivery were investigated. Oral adhesive tablets containing 5mg of brilliant blue(BB) were prepared from direct compression. Viscosity of 2% gum solutions, water absorption, fracture resistance, stickiness of tablets, and dissolution of BB in pH 6.8 dissolution medium were tested. Acacia showed good stickiness and fracture resistance, and tragacanth showed good retarding effect on the release of BB from tablets. Therefore, tablets with varing ratios of acacia and tragacanth were prepared and their physical properties were examined. In conclusion, it was possible to obtain some adequate properties by compounding acacia and tragacanth.

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Optimization of Jelly Preparation from Nopal by Response Surface Methodology (반응표면분석법을 이용한 백년초젤리 제조의 최적화)

  • Jung, Hyeun-A;Joo, Na-Mi
    • Journal of the Korean Society of Food Culture
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    • v.20 no.6
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    • pp.695-702
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    • 2005
  • To determine the optimum mixing conditions of nopal jelly, samples were prepared with various compounding ratios of gelatin(16, 18, 20, 22 and 24g), sucrose(100, 120, 140, 160 and 180g), Citric acid(2, 3, 4, 5 and 6) using a central composite design. Physical and sensory evaluations were performed and considered using a response surface methodology. The optimum mixing rates which meet sensory items is gelatin 20.19g, sucrose 141.52g and citric acid 4.04g.

FATIGUE LIFE PREDICTION OF RUBBER MATERIALS USING TEARING ENERGY

  • Kim, H.;Kim, H.Y.
    • International Journal of Automotive Technology
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    • v.7 no.6
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    • pp.741-747
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    • 2006
  • It has been almost impossible to predict the fatigue life in the field of rubber materials by numerical methods. One of the reasons is that there are no obvious fracture criteria and excessively various ways of mixing processes. Tearing energy is considered as a fracture criterion which can be applied to rubber compounds regardless of different types of fillers, relative to other fracture factors. Fatigue life of rubber materials can be approximately predicted based on the assumption that the latent defect caused by contaminants or voids in the matrix, imperfectly dispersed compounding ingredients, mold lubricants and surface flaws always exists. Numerical expression for the prediction of fatigue life was derived from the rate of rough cut growth region and the formulated tearing energy equation. Endurance test data for dumbbell specimens were compared with the predicted fatigue life for verification. Also, fatigue life of industrial rubber components was predicted.

Application of Bitemporal Classification Technique for Accuracy Improvement of Remotely Sensed Data (원격탐사 데이타의 정확도 향상을 위한 Bitemporal Classification 기법의 적용)

  • 안철호;안기원;윤상호;박민호
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.5 no.2
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    • pp.24-33
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    • 1987
  • This study aims at obtaining more effective image processing techniques and more accurately classified image in the sphere which uses remotely sensed data. For this practice, the result of land use classification compounding summer scene with winter scene and the classified result of summer scene were compared, analyzed. From the upper analysed results, we found that Bitemporal Classification technique and $tan^{-1}$transformation were effective. Particularly, dividing crop class into two classes of farmland and field was more possible by appling Bitemporal Classification technique.

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The Design of LED Module for Full-Color Display (Full-Color Display를 위한 LED Module의 Design)

  • 송유리;원창섭;최연석;임석준;안형근;한득영
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 1996.11a
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    • pp.274-277
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    • 1996
  • This paper describes the realization of the full-color to the degree of nearest white light by compounding high brightness Red, Green and Blue LEDs with appropriate proportional index. Once these three colors; red, green and blue are mixed, they are genearlly additive mixing and produce white light color contrasted to negative mixing. The luminous efficiency is defined as the product of the efficiency(lm/w), which indicates the degree of perceptual response by the human eye to unit energy(W) of light emitted by an active display devises and as the conversion efficiency of the device from electric power consumed to optical energy produced. We will deduce the each number of LEDs theoretically and design several shapes of LED displays for the full-color. Finally theoretical predictions will be compared with the measured data with different type of display designs.

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