• 제목/요약/키워드: compound-K

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자연모사를 통한 미세 고분자 포토닉 구조의 구면배열에 관한 연구 (Spherical arrangement of biomimetic polymer photonic structures)

  • 정기훈
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2007년도 춘계학술대회A
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    • pp.403-404
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    • 2007
  • Compound eyes in nature present intriguing topics in physiological optics due to their unique optical scheme for imaging. For example, a bee's eye has thousands of integrated photonic units called ommatidia spherically arranged along a curvilinear surface so that each unit points in a different direction. The omni-directionally arranged ommatidium collects incident light with a narrow range of angular acceptance and independently contributes to the capability of wide field-of-view (FOV) detection. Artificial implementation of compound eyes has attracted a great deal of research interest because the wide FOV exhibits a huge potential for medical, industrial, and military applications. So far, imaging with a FOV over $90^{\circ}$ has been achieved only with fisheye lenses which rely on bulky and expensive multiple lenses and require stringent alignment. In this talk, we will discuss about the spherical 3D arrangement of the photonic structures of biologically inspired artificial compound eyes in a small form-factor to have and the functional and anatomical similiarity with natural compound eyes.

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Isolation and Structure Determination of a Cholesterol Esterase Inhibitor from Ganoderma lucidum

  • Kim, Shin-Duk
    • Journal of Microbiology and Biotechnology
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    • 제20권11호
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    • pp.1521-1523
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    • 2010
  • Bioassay-guided fractionation of a methanol extract of Ganoderma lucidum gave a pure cholesterol esterase inhibitor. On the basis of spectroscopic analysis and comparison with data from the literature, the structure of this compound was identified as $5{\alpha},8{\alpha}$-epidioxyergosta-6,22-dien-$3{\bet}$-ol (compound I). This compound inhibited cholesterol esterase activity with an $IC_{50}$ value of $42{\mu}M$. Lineweaver-Burk plot analysis revealed that compound I is a noncompetitive inhibitor. The findings of this study suggest that compound I may be the active principle of the hypocholesterolemic effect of Ganoderma lucidum.

Preparation of Intermetallic Compound of Ternary Al-B-C System by Mechanical Alloying

  • Takahashi, Teruo;Yamashita, Michiru;Yamada, Kazutoshi;Kohzuki, Hidenori
    • 한국분말야금학회:학술대회논문집
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    • 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part2
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    • pp.1033-1034
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    • 2006
  • Metallic compound of ternary Al-B-C system was prepared by mechanical alloying (MA) using Al, boron and graphite powders as starting materials. MA was carried out using Spex 8000 mixer/mill for 50 hours in an argon atmosphere without process control reagent such as methyl alcohol. The MA powders obtained were heat-treated in vacuum at the temperature of 873 and 1273 K for 5 hour. Pure ternary Al-B-C compound was obtained in the chemical content of Al:B:C=55:27:18. The ternary compound obtained in this study has a new phase whose crystal structure is not identified yet.

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동력순환형과 동력분류형을 구현 가능한 복합형 무단변속기 (Compound CVT realizing Power Circulation Mode and Power Split Mode)

  • 최상훈;김연수
    • 한국공작기계학회논문집
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    • 제14권4호
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    • pp.96-103
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    • 2005
  • We designed the compound CVT(Continuously Variable Transmissions) by combining power circulation mode and power split mode, which have been proposed for connecting 2K-H I differential gear to the V- belt type CVU(Continuously Variable Unit), as an input coupled type. With the designed compound CVT, we carried out theoretical analysis and performance experiments for efficiency, speed ratio, power flow, and power transmission ratio. We proved that the compound CVT had a better performance than either of the power circulation mode or power split mode.

입체면 복합 폴리머 소재의 전도성 패턴 제작 기술 (Conductivity Pattern Manufacture Technology of Solid Surface Compound Polymer Material)

  • 윤신용
    • 전기학회논문지P
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    • 제65권3호
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    • pp.224-234
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    • 2016
  • This study developed the conductivity pattern of solid surface using laser direct pattern and compound polymer material technology. For development direct patterning system of solid surface, we used the laser power stabilizer, the dynamic focusing, 3D scanner S/W and the auto aligning techniques. Also For conductivity pattern, we are developed compound polymer material with additive by electro-less plating. These technologies are already used commercially. However operation and control integrated system for direct patterning of solid surface are not yet developed. The objective of this paper is to introduce the laser direct structuring for simple process improvement instead complex PCB process, and develop the operating stability and integration system. Also we implemented new application of laser direct structuring through sample manufacture.

국내생산 사료의 Aflatoxin 오염도 조사 (Survey of the Presence of Aflatoxins in Compound Feeds and Feed Ingredients)

  • 장한섭;조현정;이경은;이찬
    • 한국식품위생안전성학회지
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    • 제22권4호
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    • pp.346-352
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    • 2007
  • 2006년에서 2007년까지 국내에서 생산된 사료 중 585점(배합사료 447, 단미사료 138)의 사료에서 아플라톡신 오염도를 조사하였다. 단미사료 중 $AFB_1$$AFB_2$의 오염도는 각각 20%와 3%이었으며, 오염농도는 각각 $0.48{\sim}10.46ppb$와 0.25-0,42 ppb로 나타났다. 배합사료에서는 $AFB_1$ 오염도가 38%로 나타났으며, 평균 0.43-5.52 ppb 수준의 검출농도로 분석되었다. 그리고 조사된 사료 중 2%의 배합사료가 0.26-0.46 ppb의 농도로 $AFB_2$에 오염되어 있는 것으로 나타났다. 사료의 종류별로 아플라톡신 오염을 비교시 고기소 사료(75%)> 젖소 사료(72%)> 강피류(30%)순으로 $AFB_1$이 많이 오염되어 있는 것으로 나타났으며, $AFB_1$ 평균오염농도는 강피류(3.1 ppb)에서 가장 높았으며, 박류(2.9 ppb), 개사료(1.9 ppb) 순으로 감소되는 것으로 나타났다. 검사한 모든 시료에서 $AFG_1$$AFG_2$는 검출되지 않았다.

PE 이종강관의 소방용 배관 적용성에 관한 실험적 연구 (An Experimental Study on Piping Feasibility of PE Compound Pipe for Fire Protection Service)

  • 박정화;오천영;곽지현;손봉세
    • 한국화재소방학회논문지
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    • 제30권3호
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    • pp.55-61
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    • 2016
  • 본 연구는 현재 사용하고 있는 소방용 배관의 부식으로 인하여 발생하는 수계소화설비의 문제를 해결하기 위하여 개발한 Polyethylene (PE) 이종강관을 수계소화설비배관으로 적용할 수 있는지를 파악하기 위한 실제 화재시험을 수행하였다. 개발된 이종배관에 대한 관련시험기준이 없어 국내외 기술자료 및 시험기준을 비교분석하여 적합한 화재시험기준을 선정하여 PE 이종강관의 성능을 분석하였다. 따라서 본 배관의 성능시험에 채택한 화재시험기준은 합성수지배관과 금속배관의 두 가지의 화재시험기준을 적용하였고 총 6차례의 화재실험을 실시하여 배관성능을 평가하였다. 소방용합성수지배관의 시험기준을 적용한 1, 2차의 화재시험결과 이음쇠와 배관에서 파손이나 변형이 없었으며 5분간 내압시험을 실시한 결과에서도 누수가 없었다. 금속배관시험기준을 적용한 화재실험은 총 4회를 실시하였으며 1, 2차 실험은 습식설비를 모사한 것으로 화재시험결과는 PE 이종강관에서 누설이나 파열이 발생하지 않았으며 또한 PE 재질의 이탈 등 손상이 발생되지 않음을 확인하였다. 단, 건식설비를 모사한 3, 4차의 화재시험결과 소화수가 방출되기 이전에 PE 이종강관에서 파열, 변형 등의 손상이 발생하였다. 따라서 실험결과 습식설비를 모사한 화재시험의 경우 PE 이종강관의 융착성, 변형, 파손 등 배관의 성능에 이상이 없음을 확인하였다.

복합진자 모형의 뉴튼.오일러 알고리즘 비교 (Comparison of Newton's and Euler's Algorithm in a Compound Pendulum)

  • 하종규
    • 한국운동역학회지
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    • 제16권3호
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    • pp.1-7
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    • 2006
  • The Primary type of swinging motion in human movement is that which is characteristic of a pendulum. The two types of pendulums are identified as simple and compound. A simple pendulum consist of a small body suspended by a relatively long cord. Its total mass is contained within the bob. The cord is not considered to have mass. A compound pendulum, on the other hand, is any pendulum such as the human body swinging by hands from a horizontal bar. Therefore a compound pendulum depicts important motions that are harmonic, periodic, and oscillatory. In this paper one discusses and compares two algorithms of Newton's method(F = m a) and Euler's method (M = $I{\times}{\alpha}$) in compound pendulum. Through exercise model such as human body with weight(m = 50 kg), body length(L = 1.5m), and center of gravity ($L_c$ = 0.4119L) from proximal end swinging by hands from a horizontal bar, one finds kinematic variables(angle displacement / velocity / acceleration), and simulates kinematic variables by changing body lengths and body mass. BSP by Clauser et al.(1969) & Chandler et al.(1975) is used to find moment of inertia of the compound pendulum. The radius of gyration about center of gravity (CoG) is $k_c\;=\;K_c{\times}L$ (단, k= radius of gyration, K= radius of gyration /segment length), and then moment of inertia about center of gravity(CoG) becomes $I_c\;=\;m\;k_c^2$. Finally, moment of inertia about Z-axis by parallel theorem becomes $I_o\;=\;I_c\;+\;m\;k^2$. The two-order ordinary differential equations of models are solved by ND function of numeric analysis method in Mathematica5.1. The results are as follows; First, The complexity of Newton's method is much more complex than that of Euler's method Second, one could be find kinematic variables according to changing body lengths(L = 1.3 / 1.7 m) and periods are increased by body length increment(L = 1.3 / 1.5 / 1.7 m). Third, one could be find that periods are not changing by means of changing mass(m = 50 / 55 / 60 kg). Conclusively, one is intended to meditate the possibility of applying a compound pendulum to sports(balling, golf, gymnastics and so on) necessary swinging motions. Further improvements to the study could be to apply Euler's method to real motions and one would be able to develop the simulator.

Syntactic Verifier as a Filter to Compound Unit Recognizer

  • Jung, Han- Min;Yuh, Sang-Hwa;Kim, Tae-Wan;Park, Dong-In
    • 한국언어정보학회:학술대회논문집
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    • 한국언어정보학회 1998년도 Language, Information and Computation = Selected Papers from the 12th Pacific Asia Conference on Language, Information and Computation, Singapore
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    • pp.303-309
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    • 1998
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Development and validation of an LC-MS/MS method for determination of compound K in human plasma and clinical application

  • Kim, Jung Soo;Kim, Yunjeong;Han, Song-Hee;Jeon, Ji-Young;Hwang, Minho;Im, Yong-Jin;Kim, Jung Hyun;Lee, Sun Young;Chae, Soo-Wan;Kim, Min-Gul
    • Journal of Ginseng Research
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    • 제37권1호
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    • pp.135-141
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    • 2013
  • A rapid, sensitive and selective analytical method was developed and validated for the determination of compound K, a major intestinal bacterial metabolite of ginsenosides in human plasma. Liquid-liquid extraction was used for sample preparation and analysis, followed by liquid chromatography tandem spectrometric analysis and an electrospray-ionization interface. Compound K was analyzed on a Phenomenex Luna C18 column ($100{\times}2.00$ mm, 3 ${\mu}m$) with the mobile phase run isocratically with 10 mM ammonium acetate-methanol-acetonitrile (5:47.5:47.5, v/v/v) at a flow rate of 0.5 mL/min. The method was validated for accuracy (relative error <12.63%), precision (coefficient of variation <9.14%), linearity, and recovery. The assay was linear over the entire range of calibration standards i.e., a concentration range of 1 ng/mL to 1,000 ng/mL ($r^2$ >0.9968). The recoveries of compound K after liquid-liquid extraction at 1, 2, 400, and 800 ng/mL were $106.00{\pm}0.08%$, $103.50{\pm}0.19%$, $111.45{\pm}5.21%$, and $89.62{\pm}34.46%$ for intra-day and $85.40{\pm}0.08%$, $94.50{\pm}0.09%$, $112.50{\pm}5.21%$, and $95.87{\pm}34.46%$ for inter-day, respectively. The lower limit of quantification of the analytical method of compound K was 1 ng/mL in human plasma. The developed method was successfully applied to a pharmacokinetic study of compound K after oral administration in ten of healthy human subjects.