• Title/Summary/Keyword: compound context

Search Result 44, Processing Time 0.023 seconds

Polyaromatic Resin HP-20 Induced Accumulation of Intermediate Azaphilones in Monascus purpureus 𝚫mppC and 𝚫mpp7 Strains

  • Lim, Yoon Ji;Lee, Doh Won;Choi, Jeong Ju;Park, Si-Hyung;Kwon, Hyung-Jin
    • Journal of Microbiology and Biotechnology
    • /
    • v.29 no.6
    • /
    • pp.897-904
    • /
    • 2019
  • Monascus purpureus recombinant mppC and mpp7 knockout strains were subjected to extractive fermentation in the context of azaphilone pigment production. Inclusion of Diaion HP-20 resin resulted in the selective production of unreduced azaphilone congeners, in addition to the early intermediate FK17-P2a, from ${\Delta}mppC$ and ${\Delta}mpp7$ strains that would otherwise mainly produce reduced congeners. Structural determination of two novel unreduced azaphilones from the ${\Delta}mpp7$ strain was accomplished. The unreduced azaphilone compound was converted into the cognate reduced congener in recombinant M. purpureus strains, demonstrating its intermediate role in azaphilone biosynthesis. This study demonstrates the possibility that extractive fermentation with Diaion HP-20 resin can be used to obtain cryptic azaphilone metabolites.

Effects of Ga doping on the superconducting properties of (B1-xGax) (Ba1.25Sr0.75)(Ca0.5Er0.5)Cu2Oz

  • Ho Keun Lee
    • Progress in Superconductivity and Cryogenics
    • /
    • v.25 no.4
    • /
    • pp.14-18
    • /
    • 2023
  • We have investigated the behavior induced by Ga substitution in B-1212 system and observed an anomalous superconductor-like resistivity drop with an onset near 260 K and an offset at 248 K in the nominal (B0.65Ga0.35)(Ba1.25Sr0.75)(Er0.5Ca0.5)Cu2Oz compound. However, this property degraded with repeated cycling. Systematic studies of the superconducting properties of the (B1-xGax)(Ba1.25Sr0.75)(Er0.5Ca0.5)Cu2Oz compounds are reported and discussed in the context of the anomalous resistivity transition.

Comparative Analysis of Technology Acceptance Model : Focusing on UTAUT1 and UTAUT2 (기술수용 모델의 비교분석 : UTAUT1과 UTAUT2를 중심으로)

  • Chung, Byoung-gyu
    • Journal of Venture Innovation
    • /
    • v.1 no.2
    • /
    • pp.109-121
    • /
    • 2018
  • New technology had been introduced continually and in many cases, we approached technology persepectives when the new technology were introduced. It was very important that researching users acceptance of the new technology in the areas of marketing and strategy. Regarding to user accepatance of new technology, many research models had been exited. This study compared with 2 models which were proposed by Venkatesh et al. named UTAUT1, UTAUT2 based on the criteria which composed of application context, variables of model, the impacts of variables. The dominant matric which was applied in all functions and industries was not exited. For the purpose of improving predictability, single or compound matrics were useful according to industries and usage

Message in a Bottle: Chemical Biology of Induced Disease Resistance in Plants

  • Schreiber, Karl;Desveaux, Darrell
    • The Plant Pathology Journal
    • /
    • v.24 no.3
    • /
    • pp.245-268
    • /
    • 2008
  • The outcome of plant-pathogen interactions is influenced significantly by endogenous small molecules that coordinate plant defence responses. There is currently tremendous scientific and commercial interest in identifying chemicals whose exogenous application activates plant defences and affords protection from pathogen infection. In this review, we provide a survey of compounds known to induce disease resistance in plants, with particular emphasis on how each compound was originally identified, its putative or demonstrated mechanism of defence induction, and the known biological target(s) of each chemical. Larger polymeric structures and peptides/proteins are also discussed in this context. The quest for novel defence-inducing molecules would be aided by the capability for high-throughput analysis of candidate compounds, and we describe some issues associated with the development of these types of screens. Subsequent characterization of hits can be a formidable challenge, especially in terms of identifying chemical targets in plant cells. A variety of powerful molecular tools are available for this characterization, not only to provide insight into methods of plant defence activation, but also to probe fundamental biological processes. Furthermore, these investigations can reveal molecules with significant commercial potential as crop protectants, although a number of factors must be considered for this potential to be realized. By highlighting recent progress in the application of chemical biology techniques for the modulation of plant-pathogen interactions, we provide some perspective on the exciting opportunities for future progress in this field of research.

Single Oral Dose Toxicity Test of ACM(Added Chongmyung-tang) in Sprague-Dawley Rat (ACM의 Sprague-Dawley Rat 경구 단회 투여 독성시험)

  • Choi, Woo-Chang;Jung, In-Chul;Lim, Jong-Soon;Kim, Seung-Hyung;Lee, Sang-Ryong
    • Journal of Oriental Neuropsychiatry
    • /
    • v.23 no.2
    • /
    • pp.121-128
    • /
    • 2012
  • Objectives : This research investigates the single oral dose toxicity of ACM in SD rats. Methods : ACMs were administered to female and male SD rats, as an oral dose of 5000 mg/kg. Animals were monitored for the mortality and changes in the body weight, clinical signs and gross observation during the 14 days after dosing, upon necropsy. Results : We could not find any mortality. Compared with the control group, significant weight change was not observed in the experimental group. First day after administration, compound-colored stool was observed in all rats. After the second day of administration, the more common symptoms were not observed. There were no gross abnormalities in all cases. [ED NOTE: highlight: given the context, this is very vague] Conclusions : The results obtained in this study suggest that the approximate lethal dose of ACM in both female and male rats were considered as over 5000 mg/kg.

[ ${\beta}-cyclodextrin$ ] inclusion properties with guest molecules using hetero-bi-functional reactive dye

  • Kim, Byung-Soon;Kim, Young-Sung;Son, Young-A
    • Textile Coloration and Finishing
    • /
    • v.19 no.2
    • /
    • pp.32-35
    • /
    • 2007
  • Cyclodextrin is a cyclic oligosaccharid material which shows an ability to incorporate organic guest molecules inside their cavity area. Thus, this ${\beta}-cyclodextrin$ treatment on fiber substrates may provide the changed surface characteristics of the substrates such as solubility, chemical reactivity and spectral property. In this context, the aim of this present work is to make a bridge connection using hetero-bi-functional reactive dye between fiber substrates and ${\beta}-cyclodextrin$. In addition, the corresponding Berberine inclusion behaviors into the inner cavity of ${\beta}-cyclodextrin$ was examined. The %exhaustion of Berberine inclusion as a guest molecule within the ${\beta}-cyclodextrin$ was measured using UV-Vis spectrophotometer. The findings showed that the %exhaustion of Berberine inclusion increased with increasing the prepared dye bridge compound and ${\beta}-cyclodextrin$ host material.

Study on multi-layered Meaning effect of space under Metaphoric Process (Metaphoric Process에 의한 공간의 다층적 의미효과에 관한 연구)

  • Part, Hee-Ryoung;Kim, Soo-Yang
    • Proceedings of the Korean Institute of Interior Design Conference
    • /
    • 2007.11a
    • /
    • pp.165-168
    • /
    • 2007
  • In the modern society, the definition of life style has a special meaning. Because of the publicity of social Life, the compound numbers of behavior context and the diversify of Authority these days, the choosing life style is important for the self identity and the life activities. To erect the thesis of metaphoric process and meaning effect by stages, it will be studied and analyzed. Furthermore, studies about contrast, ambiguity, illusion, the element for meaning effect by stages, will be done. The Ubiquitous age Is a organic period for human, space and objects to interact to each other. This relationship can not be alternated by technology. Instead the technology can be a premise and because of the human being's new faculty of sensation, this age request emotional and interactive space design. In this modern life, the study of emotional and sensuous experience and metaphoric process can not be overlooked and should be researched more thoroughly to complete the theory of the new space design.

  • PDF

Geosynthetic-Reinforced Segmental Retaining Walls in Tiered Arrangement - Case Study and Field Trial Wall Instrumentation (다단식 보강토 옹벽의 설계 - 사례연구 및 시험시공)

  • Yoo, Chung-Sik;Jung, Hyuk-Sang
    • Journal of the Korean Geosynthetics Society
    • /
    • v.3 no.1
    • /
    • pp.27-36
    • /
    • 2004
  • This paper presents the results of stability analyses on soil-reinforced segmental retaining walls in a tiered arrangement. Four different walls were examined to investigate the appropriateness of their designs within the context of the current design guidelines based on limit equilibrium. Slope stability analysis against the compound failure mode, which is frequently ignored during design, was also performed based on the method recommended by FHWA design guidelines. Also presented are the results of instrumentation on a full-scale field trial wall constructed as part of this study. The implications of the findings from this study are discussed.

  • PDF

A Multi-dimensional Structure for User Resistance with the Determinants of Innovative Product Use on Virtual Reality (가상현실 환경에서의 다차원적 혁신저항 구조와 혁신 제품 사용의 결정요소)

  • Park, Hyun-jung;Shin, Kyung-shik;Choi, Jaewon
    • The Journal of Society for e-Business Studies
    • /
    • v.21 no.2
    • /
    • pp.97-119
    • /
    • 2016
  • Motion-sensing interface enhances the sense of reality of user experience in virtual reality context. This study analyzes the innovation resistance and adoption structure for Leap Motion, which provides a motion-sensing function, primarily considering the theory of perceived risk. Previous research regarding innovation resistance and adoption mainly addressed the resultant aspects of perceived risk, or the impact of perceived value on the adoption intention. This study synthetically reviews previous studies from a multi-dimensional view considering both resistance- and adoption-perspective. To do so, we identified important antecedents that affect perceived risk and value, and we analyzed the compound dynamics of perceived risk and value towards innovation resistance. As a result, we found that the antecedents included in the existent acceptance models from adoption-perspective can help reduce the level of perceived risk, and that higher perceived value leads to lower innovation resistance. Additionally, trialability can rather foster the perceived risk.

Two Statistical Models for Automatic Word Spacing of Korean Sentences (한글 문장의 자동 띄어쓰기를 위한 두 가지 통계적 모델)

  • 이도길;이상주;임희석;임해창
    • Journal of KIISE:Software and Applications
    • /
    • v.30 no.3_4
    • /
    • pp.358-371
    • /
    • 2003
  • Automatic word spacing is a process of deciding correct boundaries between words in a sentence including spacing errors. It is very important to increase the readability and to communicate the accurate meaning of text to the reader. The previous statistical approaches for automatic word spacing do not consider the previous spacing state, and thus can not help estimating inaccurate probabilities. In this paper, we propose two statistical word spacing models which can solve the problem of the previous statistical approaches. The proposed models are based on the observation that the automatic word spacing is regarded as a classification problem such as the POS tagging. The models can consider broader context and estimate more accurate probabilities by generalizing hidden Markov models. We have experimented the proposed models under a wide range of experimental conditions in order to compare them with the current state of the art, and also provided detailed error analysis of our models. The experimental results show that the proposed models have a syllable-unit accuracy of 98.33% and Eojeol-unit precision of 93.06% by the evaluation method considering compound nouns.