• Nuclear Engineering and Technology
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• 제54권8호
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• pp.2933-2940
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• 2022

Approximations such as the delete-term approximation, rare event approximation, and minimal cutset upper bound (MCUB) need to be prudently applied for the quantification of a seismic probabilistic safety assessment (PSA) model. Important characteristics of seismic PSA models indicate that preserving the success branches in a primary seismic event tree is necessary. Based on the authors' experience in modeling and quantifying plant-level seismic PSA models, the effects of applying negate-down to the success branches in primary seismic event trees on the quantification results are summarized along with the following three insights gained: (1) there are two competing effects on the MCUB-based quantification results: one tending to increase and the other tending to decrease; (2) the binary decision diagram does not always provide exact quantification results; and (3) it is identified when the exact results will be obtained, and which combination provides more conservative results compared to the others. Complicated interactions occur in Boolean variable manipulation, approximation, and the quantification of a seismic PSA model. The insights presented herein can assist PSA analysts to better understand the important theoretical principles associated with the quantification of seismic PSA models.

• Communications for Statistical Applications and Methods
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• 제24권6호
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• pp.605-625
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• 2017

This paper presents proportional odds cure models to allow spatial correlations by including spatial frailty in the interval censored data setting. Parametric cure rate models with independent and dependent spatial frailties are proposed and compared. Our approach enables different underlying activation mechanisms that lead to the event of interest; in addition, the number of competing causes which may be responsible for the occurrence of the event of interest follows a Geometric distribution. Markov chain Monte Carlo method is used in a Bayesian framework for inferential purposes. For model comparison some Bayesian criteria were used. An influence diagnostic analysis was conducted to detect possible influential or extreme observations that may cause distortions on the results of the analysis. Finally, the proposed models are applied for the analysis of a real data set on smoking cessation. The results of the application show that the parametric cure model with frailties under the first activation scheme has better findings.

• 한국신뢰성학회:학술대회논문집
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• 한국신뢰성학회 2000년도 춘계학술대회 발표논문집
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• pp.239-246
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• 2000

이 논문은 중대사고가 발생하였을때 운전원에 의하여 사고관리 방안을 수행하는 경우 그 실현성(Feasibility)을, 평가하는데 사용할 수 있는 새로운 시간의존적 신뢰도 분석방법을 제시하였다. 이 방법은 성능요구 (Performance Requirement)와 성능성취 (Performance Achievement)의 상관관계의 개념을 이용하는 신뢰도물리(Reliability Physics)와 모든 시간의존적 사고경위를 도출하는 동적사건수목 생성방법에 기초하고있다. 신뢰도물리는 성능요구변수와 성능성취변수의 비교를 이용한 신뢰도분석방법인 반면 동적사건수목 생성방법은 바람직한 해를 얻을 때까지 모든 가능한 사고경위를 도출해 내는 방법이다. 이 방법론을 정전사고시 참조원전의 공동에 비상화재시스템을 이용하여 물을 공급하는 공동범람사고관리 방안에 적용시켰다. Latin Hypercube Sampling 방법은 성능요구변수의 불확실성을 평가하는데 사용되었다. 제시된 방법론은 사고시 필요한 운전원의 방안수행 성공가능성을 평가하는데 사용될 수 있을 뿐만 아니라 궁극적으로 사고관리 절차서 개발에 도움이 될 수 있음을 보여주었다.

• 한국시뮬레이션학회논문지
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• 제14권1호
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• pp.9-18
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• 2005

Attempts to attack hosts in the network have become diverse, due to crackers developments of new creative attacking methods. Under these circumstances the role of intrusion detection system as a security system component gets considerably importance. Therefore, in this paper, we have suggested multiple intrusion detection system based on the contract net protocol which provides the communication among multiple agents. In this architecture, fuzzy rule based system has been applied for agent selection among agents competing for being activated. The simulation models are designed and implemented based on DEVS formalism which is theoretically well grounded means of expressing discrete event simulation models.

• Communications for Statistical Applications and Methods
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• 제24권4호
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• pp.397-419
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• 2017

A four-parameter extended fatigue lifetime model called the odd Birnbaum-Saunders geometric distribution is proposed. This model extends the odd Birnbaum-Saunders and Birnbaum-Saunders distributions. We derive some properties of the new distribution that include expressions for the ordinary moments and generating and quantile functions. The method of maximum likelihood and a Bayesian approach are adopted to estimate the model parameters; in addition, various simulations are performed for different parameter settings and sample sizes. We propose two new models with a cure rate called the odd Birnbaum-Saunders mixture and odd Birnbaum-Saunders geometric models by assuming that the number of competing causes for the event of interest has a geometric distribution. The applicability of the new models are illustrated by means of ethylene data and melanoma data with cure fraction.

• International Journal of Reliability and Applications
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• 제3권1호
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• pp.25-35
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• 2002

This paper presents a dynamic reliability assessment methodology for use in the safety assessment of a complex system such as a nuclear power plant. The method is applied to a dynamic analysis of the potential accident sequences that may occur during mid-loop operation in a nuclear power plant. The idea behind this approach consists of both the use of the concept of the performance achievement/requirement correlation and of a dynamic event tree generation method. The assessment of the system reliability depends on the determination of both the required performance distribution and the achieved performance distribution. The quantified correlation between requirement and achievement represents a comparison between two competing variables. It is demonstrated that this method is easily applicable and flexible in that it can be applied to any kind of dynamic reliability problem.

• 한국안전학회지
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• 제11권2호
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• pp.52-59
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• 1996

This paper presents a new approach for assessing the dynamic reliability in a complex system such as a nuclear power plant. The method is applied to a dynamic analysis of the potential accident sequences which may occur during mid-loop operation. Mid-loop operation is defined as an operation to make RCS water level below the top of the flow area of the hot legs at the junction with the reactor vessel for repairs and maintenance of steam generators and reactor coolant pumps for a specific time. The Idea behind this approach consists of both the use of the concept of the performance achievement/requirement correlation and of a dynamic event tree generation method. The assessment of the system reliability depends on the determination of both the required performance distribution and the achieved performance distribution. The quantified correlation between requirement and achievement represents a comparison between two competing variables. It is demonstrated that this method is easily applicable and flexible in that it can be applied to any kind of dynamic reliability problem.

• Annals of dermatology
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• 제30권6호
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• pp.668-675
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• 2018

Background: Drug survival, defined as the time until discontinuation, is a parameter reflecting real-world therapeutic effectiveness. Few studies have examined the influence of economic factors on the drug survival of biologic agents for psoriasis, particularly in Asian countries. Objective: To determine the drug survival for ustekinumab in real-life settings and investigate the factors affecting drug survival for psoriasis patients in Korea. Methods: We evaluated 98 psoriasis patients who were treated with ustekinumab at a single center. We analyzed the efficacy and drug survival of ustekinumab. Cox proportional hazard analysis and competing risk regression analysis were performed to reveal the factors affecting the drug survival of ustekinumab. Results: The overall mean drug survival was 1,596 days (95% confidence interval [CI], 904~2,288). Among the 39 cessations of ustekinumab treatment, 9 (23.1%) patients discontinued treatment after experiencing satisfactory results. Multivariate Cox proportional hazard analysis revealed that paying on patients' own expense was the major predictor for the discontinuation of ustekinumab (hazard ratio [HR], 9.696; 95% CI, 4.088~22.998). Competing risk regression analysis modeling of discontinuation because of factors other than satisfaction of an event also revealed that ustekinumab treatment at the patient's expense (HR, 4.138; 95% CI, 1.684~10.168) was a predictor of discontinuation rather than satisfaction. Conclusion: The results of our study revealed that the cost of biologics treatment affects the drug survival of ustekinumab and suggested that economic factors affect the drug survival of ustekinumab treatment in Korea.

• 융합정보논문지
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• 제11권1호
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• pp.102-108
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• 2021

본 연구는 기술의 융복합화가 가속화되고 있는 시점에서 최근 급성장하고 있으며, 세계시장에서 우리기업과 경쟁관계에 있는 중국 기업들의 특허분쟁 발생시 대응방안에 대해 파악하고자 하였다. 이를 위해 선행연구에서 제시된 특허분쟁 대응 방안을 전문가 심층 인터뷰를 통해 도출하고, 중국 기업의 특허담당 실무자에게 설문조사를 실시하였다. 분석결과, 중국 산업에서 특허 분쟁 발생시에 취하는 대응 방안으로는 cross licensing, 특허무효화 소송, 타회사와의 연대를 통한 소송, 로열티 지급, 특허 무효 소송 순으로 그 중요도가 나타났다. 본 연구의 결과는 특허 분쟁 발생시 기업의 특허담당 실무자들에게 가장 알맞은 대응 방안을 파악하여 적시에 대응을 하여 시간과 비용을 줄일 수 있도록 실무적인 가이드라인을 제공할 수 있을 것으로 보인다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제12권2호
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• pp.579-603
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• 2018

In this paper we propose a QoS-enhanced intelligent stochastic optimal fair real-time packet scheduler, QUEST, for 4G LTE traffic in routers. The objective of this research is to maximize the system QoS subject to the constraint that the processor utilization is kept nearly at 100 percent. The QUEST has following unique advantages. First, it solves the challenging problem of starvation for low priority process - buffered streaming video and TCP based; second, it solves the major bottleneck of the scheduler Earliest Deadline First's failure at heavy loads. Finally, QUEST offers the benefit of arbitrarily pre-programming the process utilization ratio.Three classes of multimedia 4G LTE QCI traffic, conversational voice, live streaming video, buffered streaming video and TCP based applications have been considered. We analyse two most important QoS metrics, packet loss rate (PLR) and mean waiting time. All claims are supported by discrete event and Monte Carlo simulations. The simulation results show that the QUEST scheduler outperforms current state-of-the-art benchmark schedulers. The proposed scheduler offers 37 percent improvement in PLR and 23 percent improvement in mean waiting time over the best competing current scheduler Accuracy-aware EDF.