• 한국한의학연구원논문집
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• 제2권1호
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• pp.381-401
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• 1996

The diagnostic requirements were suggested and explained regarding the systems of differentiation of syptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : -differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to reletive excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) -differentiation of diseases according to pathological changes of the viscera and their interrelation(臟腑辨證) -analysing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following odor : another name(異名), notion of diagnosis parrern(證候槪念), index of differentiation of syptoms and sings(辨證指標), the main point of diagnosis(診斷要點), analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a wayof curing a diseases(治法), prescription(處方) , herbs in common use(常用藥物), dieases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

• 정보처리학회논문지:컴퓨터 및 통신 시스템
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• 제8권5호
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• pp.103-110
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• 2019

본 연구에서는 2015 개정 교육과정에 기초하여 개발된 고등학교 '정보' 교과서의 '문제 해결과 프로그래밍' 단원에 대한 탐구성을 분석하였다. 7종 교과서에 Romey 분석법을 적용하였으며, 4개 분석항목인 본문, 자료, 활동, 평가에 대한 분석을 수행하였다. 연구 결과에 따르면, 본문, 자료, 활동, 평가의 항목에서 각각 1종, 3종, 6종, 2종의 교과서가 탐구성이 높은 것으로 나타났다. 그리고 Romey 평가지수를 기준으로 6종 교과서의 본문이 0.175~0.393로 낮게 분포되었으며, 자료 항목에서 4종 교과서가 0.058~0.226로 매우 낮았다. 평가 항목은 5종 교과서가 2~6.333로 매우 높게 분포되었으며, 교과서 간의 편차도 큰 것으로 나타났다. 그리고 새로운 교과서가 본문, 자료, 활동의 3개 분석항목에서 이전 교과서보다 탐구성이 향상되었으며, 평가 분석항목은 Romey 지수가 0.916에서 3.194로 크게 증가하여 탐구성이 과도한 것으로 나타났다. 본 연구에서는 이러한 분석 결과를 토대로 교과서의 개선 방안을 제안하였다.

• Journal of Preventive Medicine and Public Health
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• 제15권1호
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• pp.47-56
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• 1982

Korean versions of British Medical Research Council (MRC), Cornell Medical Index(CMI), and American Thoracic Society 78 (ATS-DLD-78) respiratory questionaires were compared with each other, and were tested the stability, in terms of test-retest reliability, of each questions by self-administration of those to 156 medical students. The results obtained and conclusions drawn are as follow: 1. The degree of agreements between responses to the comparable questions of CMI vs MRC, and of CMI vs ATS-DLD-78 were not satisfactory. There were, however, $71{\sim}100$ per cent of agreement between responses to the questions on Cough, Wheezing, Phlegm, Breathlessness, and Chest illness of ATS-DLD-78 vs MRC questionaire. And the ATS-DLD-78 tended to yield greater number of positive responses than MRC (See Table 4). 2. All of the coefficient of stability of each questions in 3 questionaires were statistically significant, ranged $77{\sim}100$ per cent, except that of the question on episode of cough and phlegm in ATS-DLD-78 questionaire (See Table 5-1). The question is composed of two collateral conditions, 'lasting for 3 weeks or more' and 'each year'. 3. It can be insisted that the Section-B questions of CMI is not proper for use in epidemiologic survey on respiratory illness. And rather than MRC, the ATS-DLD-78 questionaire deserves to prefer to be used in epidemiologic studies on respiratory illness. 4. In question-wording, especially, of inquiring past experience, it is possible to lessen the reliability of the question that including collateral conditions such as 'the duration lasted of symptoms', and moreover, of which words are not common usage. For example, for Korean '10days' or 'half a month' is more familiar time unit rather than 'week'.

• Journal of Microbiology and Biotechnology
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• 제20권4호
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• pp.844-851
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• 2010

Controlling the dissolved oxygen (DO) in the fed-batch culture of the medicinal mushroom Ganoderma lucidum led to a 2-fold increase of the maximum biomass productivity compared with uncontrolled DO conditions. By contrast, extracellular polysaccharide (EPS) production was two times higher under oxygen limitation (uncontrolled DO) than under increased oxygen availability (controlled DO). Morphologically, dispersed mycelium was predominant under controlled DO conditions, with highly branched hyphae, consistent with the enhanced culture growth noted under these conditions, whereas in the uncontrolled DO process mycelial clumps were the most common morphology throughout the culture. However, in both cultures, clamp connections were found. This is an exciting new finding, which widens the applicability of this basidiomycete in submerged fermentation. In rheological terms, broths demonstrated shear-thinning behavior with a yield stress under both DO conditions. The flow curves were best described by the Herschel-Bulkley model: flow index down to 0.6 and consistency coefficient up to 0.2 and 0.6 Pa $s^n$ in uncontrolled and controlled cultures DO, respectively. The pseudoplastic behavior was entirely due to the fungal biomass, and not to the presence of EPS (rheological analysis of the filtered broth showed Newtonian behavior). It is clear from this study that dissolved oxygen tension is a critical process parameter that distinctly influences G. lucidum morphology and rheology, affecting the overall performance of the process. This study contributes to an improved understanding of the process physiology of submerged fermentation of G. lucidum.

• 한국도로학회논문집
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• 제18권3호
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• pp.95-107
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• 2016

PURPOSES : This study compared two measures of traffic flow effectiveness on roads with roundabouts and signalized intersections and determined the more appropriate measure. METHODS : In addition to average delay time, the conventionally used measure, average travel time was introduced to measure traffic flow effectiveness because it is able to be obtained through field survey and reflect different travel distances and speed limits of roundabouts and signalized intersections. Using the two measures, roundabouts and signalized intersections were compared through simulations in terms of traffic flow effectiveness. RESULTS : For one-way single-lane roads, the two measures indicated consistent results that roundabouts were more effective than were signalized intersections when the traffic volume was less than 300 vphpl but vice versa when it exceeded 450 vphpl; however, the measures yielded inconsistent results when the volume was 350~400 vphpl. For one-way double-lane roads, the two measures indicated consistent results that roundabouts were more effective than were signalized intersections when the volume was less than 200 vphpl but vice versa when it exceeded 400 vphpl; however, the measures yielded inconsistent results when the volume was 250~350 vphpl. The results obtained using the two measures differed substantially for double-lane roads because behaviors such as weaving and lane changing at roundabouts are more common in double-lane roads than in single-lane roads. CONCLUSIONS : The average delay time would be lower on roads with roundabouts, but average travel time would be lower on roads with signalized intersections. Thus, evaluating the relative effectiveness of roads with roundabouts and signalized intersections by using average delay time alone would be inappropriate, whereas using average travel time as the evaluation index would yield fairer results.

• 대한한방내과학회지
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• 제38권6호
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• pp.1085-1095
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• 2017

Objectives: The purpose of this study was to investigate the efficacy of Lijin-tang-gamibang on refractory gastroesophageal reflux disease (GERD). Methods: This before-and-after study compared the first medical examination and examination at the end of medical treatment. Twelve refractory GERD patients who visited the Department of Digestive Diseases of Kyung Hee University Korean Medicine Hospital from August 14th, 2017 to October 14th, 2017, were treated with Lijin-tang-gamibang for four consecutive weeks. The clinical characteristics of refractory GERD and the efficacy of herbal medical treatment was assessed by questionnaires, the Nepean Dyspepsia Index-Korean version (NDI-K), the Korean Gastrointestinal Symptom Rating Scale (KGSRS), the Numerical Rating Scale (NRS), the Korean version of the Perceived Stress Scale (KPSS-10), the Qi Stagnation Questionnaire (QSQ), the Spleen Qi Deficiency Questionnaire (SQDQ), and the Patient Global Impression of Change (PGIC). Prolonged effects were reported upon the follow-up telephone survey two weeks after treatment. Results: After treatment with the herbal medicine Lijin-tang-gamibang, the clinical characteristics of 12 refractory GERD patients were improved, especially in terms of the most common symptoms of acid regurgitation and heartburn. Each symptom score of NDI-K, KGSRS, NRS, SQDQ, and PGIC showed significant advances. Prolonged effects were reported in NDI-K, NRS and PGIC questionnaires two weeks after treatment. Conclusions: These results suggest that Lijin-tang-gamibang is an effective treatment for refractory GERD.

• 대한한의학원전학회지
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• 제25권3호
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• pp.13-22
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• 2012

Objective : This study was conducted to compare Sasang Constitutional Medicine (SCM) and Four Humor Theory (FHT). Method : 1. The theoretical comparison was focused on the central pillars of both theories, i.e., the theories of Hippocrates and his successor Galenos as well as Lee Je-ma. 2. Research papers on SCM and FHT were collected as follows. First, relevant papers were searched for using several electronic databases: Pubmed (http://www.pubmed.org.), NDSL (http://www.ndsl.kr/index.do), KISS (http://kiss.ksstudy.com), and RISS (http://www.riss4u.net.). Keywords were 'Sasang', 'constitution', 'constitutional medicine', 'humor theory', 'Hippokrates', 'Galenos', and "Dongeuisusebowon".In addition, relevant papers were searched for using the websites of The Korean Society for the History of Medicine(http://medhist.kams.or.kr), The Korean society of Oriental medical classics (http://www.wonjeon.or.kr), The Society of Sasang Constitutional Medicine (http://www.esasang.or.kr/new_home/main.htm),and The Korean Association of Oriental Medical Physiology (http://www.ksomp.or.kr). As a result, a total of 32 papers were included in the final selection. Result & Conclusion : In this study, a comparison was made between FHT and SCM in terms of physiology, pathology and therapy. We showedthat the theories share similarities as well as differences. However, in a practical sense, the two should be characterized based on their differences rather than their similarities. In conclusion, the two have something in common, but overall, they are remarkably different from each other.

• 성인간호학회지
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• 제28권6호
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• pp.637-645
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• 2016

Purpose: The purpose of this study was to identify the occurrences and the factors contributing to constipation in the post surgical period following major orthopedic surgery. Methods: The sample included 133 patients who had surgery of the hip, knee, or spine. Patients were excluded from the study if there was a history of bowel surgery or constipation from chart review. Data were collected using questionnaires such as Korean version of Modified Barthel index (K-MBI), Hospital Anxiety and Depression Scale, and Constipation Assessment Scale (CAS) before surgery and on the third postoperative day. Results: Reports of constipation occurred in 77 instances (57.9%). The first reported defecation was within $4.0{\pm}2.2days$ following surgery. Mean days of first defecation of constipation group vs. non-constipation group was $5.5{\pm}1.7days$ vs. $2.1{\pm}1.0days$. There were statistically significant differences between patients who reported than those who did not in terms of age, length of NPO period, postoperative ADL, and the reported incidents of preoperative and postoperative depressive symptoms. Postoperative ADL, age, and NPO period were significant influencing factors of constipation and explained 52.4% of the variance. Conclusion: Constipation is a very common symptom for patients undergoing orthopedic surgery. These results indicate a need for improving patient's ADL after surgery to prevent constipation.

• 대한한의학회지
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• 제34권4호
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• pp.46-55
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• 2013

Objectives: Classifying the pattern of jaundice during diagnosis will significantly improve the outcome of common KM interventions. This study aimed at determining an objective index for accurately diagnosing heat and dampness KM patterns in patients with jaundice. Methods: We systematically reviewed laboratory findings from case reports published in the scientific literature of Korean medicine. Cases were classified as following either the heat or dampness pattern. Biochemical indices were compared using a Bayesian factor (BF) analysis and standard t-tests. Results: The laboratory findings of 32 patients were evaluated. The heat pattern was observed in 17 patients and the dampness pattern in 15. No significant differences were observed between the 2 groups in terms of white blood cell count (BF=1.659); hemoglobin concentration (BF=2.627); platelet count (BF=1.019); or levels of direct bilirubin (BF=1.453), aspartate aminotransferase (BF=1.226), alanine aminotransferase (BF=1.340), alkaline phosphatase (BF=2.344), or gamma-glutamyl transpeptidase (BF=2.782). However, total bilirubin levels were significantly higher in the dampness pattern group (BF=0.854, P-value=0.070). Conclusions: Patients with high total bilirubin levels may predominantly follow the dampness pattern, while those with low levels may predominantly follow the heat pattern. These results are expected to be useful for the development of timely and efficient KM treatments as well as new integrative therapeutic approaches for jaundice. However, further studies are essential to fully validate the utility of total bilirubin as a biomarker for differentiating between heat and dampness patterns.

• Archives of Plastic Surgery
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• 제42권5호
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• pp.601-607
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• 2015

Background Autologous or implant-based breast reconstruction after nipple-sparing mastectomy is increasingly preferred worldwide as a breast cancer treatment option. However, postoperative nipple-areola complex (NAC) necrosis is the most significant complication of nipple-sparing mastectomy. The purpose of our study was to identify the risk factors for NAC necrosis, and to describe the use of our skin-banking technique as a solution. Methods We reviewed cases of immediate autologous breast reconstruction after nipple-sparing mastectomy at our institution between June 2005 and January 2014. The patients' data were reviewed and the risk of NAC necrosis was analyzed based on correlations between patient variables and NAC necrosis. Moreover, data pertaining to five high-risk patients who underwent the donor skin-banking procedure were included in the analysis. Results Eighty-five patients underwent immediate autologous breast reconstruction after nipple-sparing mastectomy during the study period. Partial or total NAC necrosis occurred in 36 patients (43.4%). Univariate analysis and binary regression modeling found that body mass index, smoking history, radiation therapy, and mastectomy volume were significantly associated with NAC necrosis. Of the 36 cases of NAC necrosis, 31 were resolved with dressing changes, debridement, or skin grafting. The other five high-risk patients underwent our prophylactic skin-banking technique during breast reconstruction surgery. Conclusions NAC necrosis is common in patients with multiple risk factors. The use of the skin-banking technique in immediate autologous breast reconstruction is an attractive option for high-risk patients. Banked skin can be used in such cases without requiring additional donor tissue, with good results in terms of aesthetic and reconstructive outcomes.