• BMB Reports
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• v.57 no.3
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• pp.149-154
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• 2024

The stomach has emerged as a crucial endocrine organ in the regulation of feeding since the discovery of ghrelin. Gut-derived hormones, such as ghrelin and cholecystokinin, can act through the vagus nerve. We previously reported the satiety effect of hypothalamic clusterin, but the impact of peripheral clusterin remains unknown. In this study, we administered clusterin intraperitoneally to mice and observed its ability to suppress fasting-driven food intake. Interestingly, we found its synergism with cholecystokinin and antagonism with ghrelin. These effects were accompanied by increased c-fos immunoreactivity in nucleus tractus solitarius, area postrema, and hypothalamic paraventricular nucleus. Notably, truncal vagotomy abolished this response. The stomach expressed clusterin at high levels among the organs, and gastric clusterin was detected in specific enteroendocrine cells and the submucosal plexus. Gastric clusterin expression decreased after fasting but recovered after 2 hours of refeeding. Furthermore, we confirmed that stomachspecific overexpression of clusterin reduced food intake after overnight fasting. These results suggest that gastric clusterin may function as a gut-derived peptide involved in the regulation of feeding through the gut-brain axis.

• Journal of Korean Society on Water Environment
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• v.25 no.6
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• pp.855-862
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• 2009

This paper pointed out major problems of land use regulation policy surrounding Paldang Lake as follows: (1) inefficient management system, (2) inconsistent administrative management, (3) illogical selection of regulated area, (4) contradictory present system, and (5) controversial discharge control. Several regulation laws for the land-use surrounding Paldang Lake caused confusion of application and inefficiency of management. Amendment of regulation laws made it possible that the regulated area was developed, which resulted in the deterioration of water quality. In addition, successive regulations without scientific implementation overexpanded regulated area and focus on the discharge concentration of contaminated sources stimulated development of small size sources. To overcome these problems, we suggested reestablishment of regulated area, differentiation of regulation amendments, and flexibility in the application of regulation. It is necessary to arrange regulated area based on the efficient land use management and scientific implementation and then to mitigate land use regulation under the sustainable development. For the flexible application of regulation, it is required to amend the rule in response to the change of environmental condition and development of environmental techniques.

• Journal of Korea Multimedia Society
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• v.25 no.9
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• pp.1338-1347
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• 2022

In recent years, the number of Chinese college students in unhealthy or sub-healthy state in terms of mental health accounts for about 30% and has been going up. As we know, college students are in the middle of youth, an important stage of physical and psychological development. In this case, how to regulate mental health will become an important research direction. Based on emotion regulation theory, this thesis discussed the impact that 'healing animation' had on college students' psychological capital, and how emotion regulation had done its work in the process. According to documents research and empirical study, 'healing animation' is positively affecting the psychological capital of college students through the medium -- emotion regulation. Finally, this thesis provided a practical layout to accumulate college students' psychological capital, and theoretical reference for 'healing animation' as well.

• Journal of the Korean Home Economics Association
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• v.43 no.3 s.205
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• pp.185-197
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• 2005

The purpose or this study was to investigate the effects of children's internal (age, sex, self-respect) and external (maternal belief, childrearing behavior) variables on self-regulation. The subjects were 2004-and-5-year-olds, their mothers, and teachers. Children's age, sex, and self-respect had m influence on self-regulation; that is 5-year-olds were higher than 4-year-olds for behavioral self-regulation, girls were higher than boys for cognitive and behavioral self-regulation, and the high self-respect group was higher than the low self-respect group for cognitive self-regulation. The psychological controlling and externally directed strategies had a negative influence on children's self-regulation. Maternal affectionate childrearing behavior had an influence on children's self-regulation; that is the high affectionate group had children with higher self-regulation.

• The Journal of Korean Academic Society of Nursing Education
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• v.24 no.4
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• pp.424-432
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• 2018

Purpose: The purpose of this study was to examine the relationship between nursing professionalism, academic emotional regulation, and college life adjustment level and to identify the influence of nursing professionalism and academic emotional regulation on college life adjustment. Methods: Data collection was conducted with 142 junior and senior nursing college students using structured self-reported questionnaires. Data were analyzed using descriptive statistics, independent t-tests, one-way ANOVA, Pearson correlation coefficient, and hierarchical multiple regression analysis using SPSS 22.0. Results: There was a positive correlation between nursing professionalism, academic emotional adjustment, and college life adjustment. The significant predictors of overall college life adjustment were major satisfaction, nursing professionalism, and academic emotional regulation. The significant predictors of clinical practice adjustment were gender, major satisfaction, and nursing professionalism. Conclusion: When developing a program to improve college life adjustment in nursing college students, it is necessary to find ways to improve nursing professionalism and academic emotional regulation as well as major satisfaction.

• Child Health Nursing Research
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• v.27 no.1
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• pp.24-33
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• 2021

Purpose: This study aimed to evaluate the effects of a rational emotive behavior therapy (REBT)-based emotional regulation program for mothers of premature infants in the neonatal intensive care unit (NICU). Methods: The study utilized a nonequivalent control group pretest-posttest design. Seventeen mothers were recruited for the experimental group and 21 mothers for the control group. Data were collected from July 9, 2018, to Oct 12, 2018 from mothers of premature infants in the NICU regarding parental stress, state anxiety, depression, and maladaptive cognitive emotion regulation. The experimental group received eight sessions of the REBT-based emotional regulation program for 3~4 weeks, and the control group only received standard nursing care. Results: Significant differences were found between the two groups in maladaptive cognitive emotion regulation (Z=-3.88, p<.001), stress (Z=-2.76, p=.006), state anxiety (Z=-3.72, p<.001), and postpartum depression(Z=-2.62, p=.009) after the intervention in the experimental group. Conclusion: The REBT-based emotional regulation program for mothers of premature infants was effective for reducing maladaptive cognitive emotion regulation, stress, anxiety, and postpartum depression. Therefore, it may be necessary to provide an REBT-based emotional regulation program for mothers of premature infants in the NICU in clinical practice.

• Journal of Korean Academy of Nursing Administration
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• v.14 no.3
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• pp.321-331
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• 2008

Purpose: This study examined the association of job satisfaction and job stress with the self regulation of nurses. Method: This research was descriptive in its design and used a self-administered questionnaire. The study subjects were 173 nurses who worked in the three university teaching hospitals. The instruments used in the study were self-regulation scale, job satisfaction scale and job stress scale. The data were analyzed by ANOVA, t-test, Pearson Correlation Coefficient, and multiple regression. Results: The mean score of self regulation, job satisfaction and job stress were 4.58, 1.90 and 3.31, respectively. The degree of error and confidence in decision making of the study subjects was associated with the extent of job satisfaction and job stress. Conclusion: Self regulation made an influence in a statistically significant way on nurses' job satisfaction and job stress. Therefore, we need to develop strategies to enhance the self regulation of nurses to improve their job satisfaction and job stress in a positive way.

• Journal of Microbiology and Biotechnology
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• v.31 no.9
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• pp.1231-1240
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• 2021

Members of the genus Bacillus are known to play an important role in promoting plant growth and protecting plants against phytopathogenic microorganisms. In this study, 21 isolates of Bacillus spp. were obtained from the root micro-ecosystem of Suaeda glauca. Analysis of the 16S rRNA genes indicated that the isolates belong to the species Bacillus amyloliquefaciens, Bacillus velezensis, Bacillus subtilis, Bacillus pumilus, Bacillus aryabhattai and Brevibacterium frigoritolerans. One of the interesting findings of this study is that the four strains B1, B5, B16 and B21 are dominant in rhizosphere soil. Based on gyrA, gyrB, and rpoB gene analyses, B1, B5, and B21 were identified as B. amyloliquefaciens and B16 was identified as B. velezensis. Estimation of antifungal activity showed that the isolate B1 had a significant inhibitory effect on Fusarium verticillioides, B5 and B16 on Colletotrichum capsici (syd.) Butl, and B21 on Rhizoctonia cerealis van der Hoeven. The four strains grew well in medium with 1-10% NaCl, a pH value of 5-8, and promoted the growth of Arabidopsis thaliana. Our results indicate that these strains may be promising agents for the biocontrol and promotion of plant growth and further study of the relevant bacteria will provide a useful reference for the development of microbial resources.

• Korean Journal of Human Ecology
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• v.19 no.2
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• pp.285-294
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• 2010

This study examined the relationship between children's school adjustment and their emotion regulation. The subjects were 122 1st grade students selected from one elementary school in Incheon. Teachers rated each child using the Emotion Regulation Scale (Lee, 1997) and School Adjustment Scale (Chi & Jung, 2006). The data were analyzed by using descriptive statistics, t-test, correlation analysis, and stepwise regressions. The children's emotion regulation and school adjustment were differed by sex of the child. The girls were assessed to be better adapted in emotion regulation and school adjustment than the boys. The children's emotion regulation was positively related to the children's school adjustment. In addition, the children's emotion regulation predicted how well they would adjust to school life.

• BMB Reports
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• v.49 no.2
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• pp.111-115
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• 2016

Caffeine has been proposed to have several beneficial effects on obesity and its related metabolic diseases; however, how caffeine affects adipocyte differentiation has not been elucidated. In this study, we demonstrated that caffeine suppressed 3T3-L1 adipocyte differentiation and inhibited the expression of CCAAT/enhancer binding protein (C/EBP)α and peroxisome proliferator-activated receptor (PPAR)γ, two main adipogenic transcription factors. Anti-adipogenic markers, such as preadipocyte secreted factor (Pref)-1 and Krüppel-like factor 2, remained to be expressed in the presence of caffeine. Furthermore, 3T3-L1 cells failed to undergo typical mitotic clonal expansion in the presence of caffeine. Investigation of hormonal signaling revealed that caffeine inhibited the activation of AKT and glycogen synthase kinase (GSK) 3 in a dose-dependent manner, but not extracellular signal-regulated kinase (ERK). Our data show that caffeine is an anti-adipogenic bioactive compound involved in the modulation of mitotic clonal expansion during adipocyte differentiation through the AKT/GSK3 pathway.