• 지역사회간호학회지
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• 제30권4호
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• pp.449-459
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• 2019

Purpose: The aim of this study is to explore different types of self-rated health trajectories among one-person households in Korea. Methods: We used five time-point data derived from Korea Health Panel (2011~2015). A latent growth curve modeling was used to assess the overall feature of self-rated health trajectory in one-person households, and a latent class growth modeling was used to determine the number and shape of trajectories. We then applied multinomial logistic regression on each class to explore the predicting variables. Results: We found that the overall slope of self-rated health in one-person households decreases. In addition, latent class analysis demonstrated three classes: 1) High-Decreasing class (i.e., high intercept, significantly decreasing slope), 2) Moderate-Decreasing class (i.e., average intercept, significantly decreasing slope), and 3) Low-Stable class (i.e., low intercept, flat and nonsignificant slope). The multinomial logistic regression analysis showed that the predictors of each class were different. Especially, one-person households with poor health condition early were at greater risk of being Low-Stable class compared with High-Decreasing class group. Conclusion: The findings of this study demonstrate that more attentions to one-person households are needed to promote their health status. Policymakers may develop different health and welfare programs depending on different characteristics of one-person household trajectory groups in Korea.

• 동아시아식생활학회지
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• 제9권3호
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• pp.289-301
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• 1999

The purpose of this study is to investigate the food habits and the dietary intake of female college students at day and night class in the Kyunggido area. The questionnaires were collected from 294 students(151 day class and 143 night class students) out of 350 in total. The results are as follows: Breakfast for day class students and breakfast and dinner of night class students were skipped more than 3 times a week. The main reason was short of time. In the behavior of food intake, the frequency of yellow-green vegetables, milk and seaweeds intake was low in all respondents. 18.4% of night class students ate out 3 times a day. In the kind of menu for eating out, Korean food was the most frequent. snack food the second, and fast food came last. 23.9% of students ate something 2 or 3 times a day between meals. The main reason for eating between meals was the desire to eat for day class students, and hunger for the night time students. Consumption of coffee was 0.76 cup a day Daily mean of calory intake was 1.394 kcal and the ratio of carbohydrate. protein lipid was 61:14:25. The intakes of iron and niacin of the day class students were higher than those of night class students. There was no significant difference in intake of other nutrients between day and night class students. Intake of calcium and iron did not reach 50% of Korean RDA.

• 대한치과교정학회지
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• 제24권4호
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• pp.827-839
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• 1994

This study was conducted to assess the positional changes of hyoid bone following the use of activator in Angles class III malocclusion patients with functional factors. For this study, 40 Angle's class I patients and 40 Angle's class III patients, totally 80 subjects were used. They are all in Hellman's dental age IIIB-IIIC ranges. In lateral cephalogram to compare Angle's class I group and Angle's class III group, and the positional changes of the hyoid bone before and after the use of activator in Angle's class III malocclusion group. The results were obtained as follows; 1. Comparison of Angle's class I group and Angle's class III group. In comparison to Angle's class I group, hyoid bone is more anteriorly and superiorly positioned in Angle's class III group. The hyoid bone showed reverse inclination to the mandibular plane in Angle's class III malocclusion group. 2. Comparison of the hyoid positional change before and after use of Activator in Angle's class III malocclusion group. The hyoid bone is displaced posteriorly and inferiorly in vertical relationship. The hyoid bone also showed counter-clockwise rotation. 3. No statistical difference was found between after Activator use data of Angle's class m malocclusion group and Angle's class I group. It is concluded that the hyoid bone in Angle's class III malocclusion group changed its position, similar to Angle's class I malocclusion group.

• 한국식품영양학회지
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• 제10권2호
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• pp.201-207
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• 1997

경기 북부 지역의 3개 전문대학에서 주, 약간별 학생들의 학교식당 이용실태를 조사하였다. 학교식당의 이용율에서 거의 매일 이용하는 주간 학생은 64.29%였고, 야간 학생들은 44.35%로 주간 학생의 이용이 더 많았다. 학교식당을 이용하는 이유로는 '달리 먹을 만한 장소가 없어서'가 주, 야간 각각 49.38, 68.01%로 나타났고, 다음으로는 '가격이 저렴해서', '시간이 절약되므로'의 순으로 나타났다. 학교식당을 이용하지 않는 이유로는 주간의 경우 52.09%, 야간의 경우 31.99%가 '맛이 없어서' 이용하지 않는 것으로 나타났고, 학교식당을 이용하지 않는 경우 주간의 경우 68.63%, 야간의 경우 37.37%가 학교 밖에서 매식하는 것으로 나타났다. 평균적인 식사의 형태는 밥식>라면, 국수류>과자류>빵류의 순이었다. 학교식당의 음식에 대한 만족도는 음식의 양을 제외하고는 맛, 기호, 반찬수 등에서 만족도가 낮은 것으로 나타났다. 학교식당의 개선점으로는 '음식의 맛과 질이 향상되어야 한다'는 점에 가장 많이 응답했고, 그 다음으로 '메뉴가 다양해야 한다', '가격이 저렴해야 한다', '위생적이어야 한다'의 순으로 나타났다.

• IMMUNE NETWORK
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• 제23권2호
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• pp.17.1-17.16
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• 2023

Latent membrane protein 2A (LMP2A), a latent Ag commonly expressed in Epstein-Barr virus (EBV)-infected host cells, is a target for adoptive T cell therapy in EBV-associated malignancies. To define whether individual human leukocyte antigen (HLA) allotypes are used preferentially in EBV-specific T lymphocyte responses, LMP2A-specific CD8⁺ and CD4⁺ T cell responses in 50 healthy donors were analyzed by ELISPOT assay using artificial Ag-presenting cells expressing a single allotype. CD8⁺ T cell responses were significantly higher than CD4⁺ T cell responses. CD8⁺ T cell responses were ranked from highest to lowest in the order HLA-A, HLA-B, and HLA-C loci, and CD4⁺ T cell responses were ranked in the order HLA-DR, HLA-DP, and HLA-DQ loci. Among the 32 HLA class I and 56 HLA class II allotypes, 6 HLA-A, 7 HLA-B, 5 HLA-C, 10 HLA-DR, 2 HLA-DQ, and 2 HLA-DP allotypes showed T cell responses higher than 50 spot-forming cells (SFCs)/5×105 CD8⁺ or CD4⁺ T cells. Twenty-nine donors (58%) showed a high T cell response to at least one allotype of HLA class I or class II, and 4 donors (8%) had a high response to both HLA class I and class II allotypes. Interestingly, we observed an inverse correlation between the proportion of LMP2A-specific T cell responses and the frequency of HLA class I and II allotypes. These data demonstrate the allele dominance of LMP2A-specific T cell responses among HLA allotypes and their intra-individual dominance in response to only a few allotypes in an individual, which may provide useful information for genetic, pathogenic, and immunotherapeutic approaches to EBV-associated diseases.

• 대한치과교정학회지
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• 제17권1호
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• pp.63-72
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• 1987

This is to investigate the difference between craniofacial correlation of Angle's class III malocclusion and that of normal occlusion. For this investigation, 28 adult males and famales, who have class III malocclusion, and 35 adult males and 46 adult famals., who have normal occlusion were selected to measure actual dimension of cranial base and to investigate ratio of various parts of maxillofacial skeleton against cranial base. Class III malocclusion were, also , classified based on SNA and SNB angle in normal range. Results were as follows. 1. In class III malocclusion, actual dimension of cranial base were appeared to be less than normal occlusion in both sex. 2. In class III malocclusion, values were less than normal occlusion in BN/ptm-A in both sex, but had no significance between two. 3. In class III malocclusion, ramal inclination, mandible inclination, BN/Go-Pog, lower genial angle were appeared to be greater. Thus, characteristic mandibular protrusive appearance of class III malocclusion was due to relative ratio and morphologic characteristic of mandibular body dimension against cranial base. 4. In class III malocclusion, upper incisors were labially tilted and lower incisors were lingually tilted compared to normal occlusion. 5. In typing of class III malocclusion, the most common type was found to be one which maxillas were in normal range, while mandibles were in protrusive tendency.

• Radiation Oncology Journal
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• 제23권2호
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• pp.116-122
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• 2005

목적: 히스톤탈아세틸화효소 억제제는 그 자체의 항암효과뿐만 아니라 방사선 감작제로서의 효과가 점차분명해져가고 있다. 최근 Class I 특이적인 히스톤탈아세틸화효소 억제제의 개발로 계층 특이적인(Class specific) 연구가 가능해짐에 따라, 본 연구에서는 서로 다른 히스톤탈아세틸화효소억제제의 방사선감작효과를 비교함과 동시에 p53 발현도의 차이가 히스톤탈아세틸화효소억제제의 방사선 감수성에 미치는 영향을 알아보고자 하였다. 대상 및 방법: 이를 위해 p53 발현도가 매우 낮은 HeLa 세포에 p53의 핵 외 수송을 억제하여 세포질 내 분해를 차단하는 Leptomycin B를 처리하여 p53의 발현도를 현저하게 높인 후, Trichostatin와 SK7041의 방사선 민감도를 비교 관찰하였다. 결과: 세포생존곡선, SER 및 SF2를 비교 분석 시, p53의 발현이 높은 Leptomycin B 처리군에서 Trichostatin A가 Class I HDAC만을 억제하는 SK7041에 비해 유의하게 높은 방사선 감작효과를 나타내었다. 이는 p53이 Class I 특이적 억제제인 SK7041과 Class I과 II를 모두 억제하는 TSA의 방사선감작효과에 미치는 영향의 차이에 기전적으로 관여함을 시사한다. 결론: Leptomycln B에 의해 유도된 p53의 발현증가는 Class I과 Class I과 II를 모두 억제하는 TSA의 방사선 감작효과를 증강시킨다.

• IMMUNE NETWORK
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• 제11권6호
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• pp.412-415
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• 2011

Hypocrellin A has gained much attention in recent years due to its light-induced antitumor, antifungal and antiviral activities. Here we report that hypocrellin A exerts immunomodulatory effects on MHC-restricted presentation of antigen. Hypocrellin A inhibited class II-MHC restricted presentation of exogenous antigen, but not class I MHC-restricted presentation of exogenous antigen, in dendritic cells. Hypocrellin A also inhibited the cytosolic pathway of endogenous antigen presentation. However, hypocrellin A did not inhibit the expression of class I and class II MHC molecules on dendritic cells (DCs), the phagocytic activity of DCs, or the $H-2K^b$-restricted presentation of a synthetic peptide, SIINFEKL. These results show that hypocrellin A differentially modulates the MHC-restricted antigen presentation pathways.

• 대한수학회보
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• 제56권2호
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• pp.373-382
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• 2019

In this note, we mainly discuss strongly Gorenstein hereditary rings. We prove that for any ring, the class of SG-projective modules and the class of G-projective modules coincide if and only if the class of SG-projective modules is closed under extension. From this we get that a ring is an SG-hereditary ring if and only if every ideal is G-projective and the class of SG-projective modules is closed under extension. We also give some examples of domains whose ideals are SG-projective.

• 한국간호교육학회지
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• 제21권1호
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• pp.141-149
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• 2015

Purpose: This study was carried out to describe the process and evaluation of a critical thinking class for new community health practitioners. Methods: The case study design was used to develop and evaluate a critical thinking class for 46 participants in the community health practitioners training program. The class was held two hours a week for 8 weeks. Critical thinking disposition was tested before and after the class and critical skill was graded according to the final test score. Data analysis was performed using descriptive statistics and paired t-tests using SPSS WIN 20.0. Results: Clinical critical thinking competences were identified through the literature review. The case situations with questions guiding the problem-solving process were developed and used for group discussion. Critical thinking disposition of participants was determined to have increased slightly after having taken the class. 17.4% of the participants had a competency level high enough to solve a problem and half of them stayed at the level of understanding of critical thinking. Compared with the class's satisfaction with the relevance to their jobs, the satisfaction with the learning method and instructor was high. Conclusion: The findings of this research will serve as the basis for developing critical thinking classes for community health nurses in order to improve their critical thinking competence.