• Korean Journal of Biological Psychiatry
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• v.4 no.2
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• pp.194-197
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• 1997

Neural network models, also known as connectionist models or PDP models, simulate some functions of the brain and may promise to give insight in understanding the cognitive brain functions. The models composed of neuron-like elements that are linked into circuits can learn and adapt to its environment in a trial and error fashion. In this article, the history and principles of the neural network modeling are briefly reviewed, and its applications to psychiatry are discussed.

• Journal of Korean Neurosurgical Society
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• v.54 no.6
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• pp.484-488
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• 2013

Objective : To examine the synergistic effects of both computer-assisted cognitive rehabilitation (CACR) and transcranial direct current stimulation (tDCS) on cognitive function in patients with stroke. Methods : The current double-blind, sham-controlled study enrolled a total of 11 patients who were newly diagnosed with stroke. The patients of the tDCS group (n=6) completed sessions of the Korean computer-assisted cognitive rehabilitation program five times a week for 30 minutes a session during a mean period of 18.5 days concomitantly with the anodal tDCS over the bilateral prefrontal cortex combined with the CACR. The patients of the control group (n=5) also completed sessions of the sham stimulation during a mean period of 17.8 days. Anodal tDCS over bilateral prefrontal cortex (F3 and F4 in 10-20 EEG system) was delivered for 30 minutes at an intensity of 2 mA. Cathode electrodes were applied to the non-dominant arm. All the patients were evaluated using the Seoul Computerized Neuropsychological Test (SCNT) and the Korean Mini-Mental State Examination. Results : Mann-Whitney U test revealed a significant difference between the two groups. The patients of the tDCS group achieved a significant improvement in the post/pre ratio of auditory continuous performance test and visual continuous performance test on the SCNT items. Conclusion : Our results indicate that the concomitant use of the tDCS with CACR to the prefrontal cortex may provide additional beneficial effects in improving the cognitive dysfunction for patients with stroke.

• The Journal of the Korea Contents Association
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• v.20 no.10
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• pp.726-737
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• 2020

This study analyzed 4,284 elderly people aged 65 or older by SPSS 22.0 in the 7th data of 「2018 Korean Longitudinal Study of Ageing(KLoSA)」 to confirm the effect of the health-promoting behavior of the elderly on life satisfaction through cognitive function. The cognitive function level of the subjects was 13.8% doubtful about dementia, 23.8% cognitive decline, and 62.4% normal, and the satisfaction level of life was 59.304 points. The results of the study were as follows: First, the difference in cognitive function according to demographic characteristics was significant in gender, age, education, religion, and marriage factors. Second, the satisfaction of the elderly's life according to demographic characteristics was confirmed to have significant differences in gender, age, education, religion, and marriage factors. Third, the satisfaction of the elderly's life was significantly positive in drinking and regular exercise factors among independent variable the health-promoting behavior when cognitive function was mediated. On the other hand, The significant negative effect of the restriction of daily life activities was confirmed. In this way, the mediating effect of cognitive function was verified in the effect of the health-promoting behavior on the satisfaction of the elderly life.

• Women's Health Nursing
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• v.22 no.3
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• pp.182-190
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• 2016

Purpose: This study was done to identify effects of cognitive function and cancer coping on quality of life among women with breast cancer treated with antineoplastic agents. Methods: The study was correlational research and participants were 145 women with breast cancer who had received antineoplastic agents. Data were collected from October to November, 2015 via online replies. Cognitive function was measured with the Functional Assessment of Cancer Therapy-Cognitive Function Version-3 (FACT-Cog), cancer coping, with the Korean Cancer Coping Questionnaire (K-CCQ), and quality of life with the Functional Assessment of Cancer Therapy-Breast Version-4 (FACT-B). Data were analyzed using descriptive statistics, t-test, ANOVA, $Scheff{\acute{e}}$ test, ANCOVA, Bonferroni test, partial correlation coefficient, and hierarchical multiple regression with SPSS 21. Results: Cognitive functions, total individual coping, and interpersonal coping explained 42% of quality of life. Cognitive function (${\beta}=.35$, p<.001) was the best predictor of quality of life, followed by total individual coping (${\beta}=.34$, p<.001), and interpersonal coping (${\beta}=.26$, p<.001). Conclusion: Results indicate that cognitive function and cancer coping are meaningful factors for quality of life among breast cancer survivors. Therefore when developing intervention programs for these women, content on cognitive function and coping skills as well as coping resources should be included.

• Journal of the Korean neurological association
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• v.36 no.4
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• pp.302-309
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• 2018

Background: Although orthostatic hypotension (OH) and cognitive impairment (CI) are common non- motor symptoms of Parkinson's disease (PD), the relationship between OH and CI remains to be clarified. This study was aimed to investigate the relationship between OH and CI in PD. Methods: We recruited 192 patients who were diagnosed as PD based on the UK Brain Bank diagnostic criteria. The Hoehn & Yahr stages were ranged I to III and patients underwent extensive clinical evaluation, including brain magnetic resonance imaging (MRI) for cerebral white matter hyperintensity (WMH), tilt table test, the Korean version of Montreal Cognitive Assessments and the Korean version of Mini-Mental Status Examination in one month from the first clinic visit. The participants were divided into two groups according to the presence of OH (OH+ vs. OH-) and cognitive function (cognitive normal, CN vs. CI), respectively. Results: Significant relationship between OH and cognitive function (p=0.04) was found in our patients. The patients with OH+ had higher risk of CI by 2.6 times than that of OH- patients. Maximum heart rate change during tilt table test was correlated with cognitive function and white matter changes, whereas blood pressure change during tilt table test showed no correlation with those parameters. Conclusions: There was significant relationship between OH and CI in PD. Therefore, PD patients with either symptom may need periodic evaluation and proper management for OH and cognitive functions.

• Journal of Advanced Technology Convergence
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• v.3 no.3
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• pp.37-45
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• 2024

This study reviews the literature on the utilization of gamification elements in digital applications for cognitive assessment and rehabilitation of the elderly, focusing on both domestic and international research from 2015 to 2024. Following the PRISMA methodology, inclusion and exclusion criteria were applied to align with the research objectives. Out of 1,718 initial studies, 18 were ultimately analyzed after a screening and filtering process. The results of this literature review indicate a growing interest in cognitive training and other interventions aimed at mitigating cognitive decline among the elderly. Additionally, it was found that the gamification elements of digital applications are effective in engaging elderly users and improving cognitive functions such as memory, attention, and executive function. The findings of this study suggest that integrating gamification elements can enhance user engagement and provide practical solutions for cognitive health management. Further research is needed to explore the long-term effects and broader applicability of these digital interventions.

• Physical Therapy Rehabilitation Science
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• v.13 no.3
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• pp.332-342
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• 2024

Objective: With the proportion of the elderly population in Korea reaching 17.5% in 2022 and projected to increase to 20.6% by 2025, 30.1% by 2035, and 43% by 2050, the accelerated aging of the population is raising societal concerns about elderly care. Maintaining mobility is crucial for a healthy and independent old age. Design: Cross-sectional study Methods: This study investigates the effects of dual-task performance on gait variables and cognitive function in older adults. This cross-sectional study involved 60 older adults aged 65 and above, categorized into a dementia group (Korean version of Montreal Cognitive Assessment (MoCA-K) score ≤ 22) and a control group (MoCA-K score ≥ 23). Cognitive and gait functions were assessed using the GAITRite system (GAITRite system, CIR Systems Inc., USA), measuring gait variables (speed, stride length, etc.) before and after dual-task performance. The assessments were conducted under a single-blind condition, and data were analyzed using SPSS (ver. 25.0, SPSS Inc., USA). Results: The dementia group scored lower on cognitive assessments compared to the control group (p<0.05). In dual-task performance evaluations, the dementia group exhibited longer total task times and lower accuracy than the control group (p<0.001), while reaction times were longer but not statistically significant. GAITRite system analysis revealed that the dementia group had reduced gait speed and stride length compared to the control group (p<0.05). However, the difference in gait time was not statistically significant. The study results indicate that older adults with dementia show significant differences in cognitive function and gait performance, with notable impacts under dual-task conditions. Conclusions: These findings underscore the effect of cognitive decline on gait and provide valuable insights for predicting gait and cognitive function deterioration in dementia, which can aid in developing fall prevention strategies.

• Journal of the Korean Dietetic Association
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• v.27 no.4
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• pp.248-262
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• 2021

This study examined the effect of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet of the Korean multi-domain dementia prevention program on the cognitive functions of the elderly with dementia risk factors. We developed the program including nutrition, exercise, cognitive training, vascular disease prevention, and motivation. One- hundred and fifty-three participants aged 60~79 years with at least 1 dementia risk factor were randomly assigned in a 1:1:1 ratio to the facility-based intervention (FMI), home-based intervention (HMI), and the control group. The nutrition education program consisted of 10 classes over 24 weeks: the FMI received 7 group sessions and three 1:1 sessions, the HMI received 4 group sessions and three 1:1 sessions with 3 homework sessions. The Nutrition Quotient for Elderly (NQ-E) and the Mini Nutritional Assessment (MNA) were used to evaluate nutritional status. The Repeatable Battery for the Assessment Neuropsychological Status (RBANS), Korean Mini-Mental State Examination (K-MMSE), and the Cognitive Complaint Interview (CCI) were used to evaluate cognitive functions. A total of 136 people completed the program with an 11.1% dropout rate. The NQ-E (P=0.009) and RBANS (P=0.001) scores significantly increased in the FMI (N=45) and HMI (N=49) groups compared to the control group (N=42) after the study. The changes in the score of MNA and CCI did not differ significantly between groups. In conclusion, the nutritional intervention which focused on the MIND diet as a part of a multi-domain intervention program had a positive effect on the improvement of healthy eating habits and cognitive function scores in the high-risk dementia group.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.8 no.11
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• pp.3638-3654
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• 2014

Cognitive Radio (CR) users need to sense the environment or channel at regular time interval for sharing the spectrum band of the primary users (PUs). Once find the spectrum idle, CR users start their transmission through it. Even while transmitting, they need to continue the sensing process so that they can leave the spectrum immediately whenever find a PU wanting to use the band. Therefore, detecting PUs is one of the main functions of cognitive radio before transmission and higher the detection probability ensures better protection to the primary users. However, it is not possible to attain a high detection probability (or a low miss detection probability) and low false alarm probability simultaneously as there is a tradeoff between false alarm probability ($P_{fa}$) and the probability of detection ($P_d$). In this paper, the author has provided a comprehensive study on different sensing techniques and discussed their advantages and disadvantages. Moreover, it is expected that, with this article, readers can have a through understanding of sensing techniques in CR and the current research trends in this area.

• Molecules and Cells
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• v.43 no.3
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• pp.215-221
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• 2020

The olfactory bulb (OB) has an extremely higher proportion of interneurons innervating excitatory neurons than other brain regions, which is evolutionally conserved across species. Despite the abundance of OB interneurons, little is known about the diversification and physiological functions of OB interneurons compared to cortical interneurons. In this review, an overview of the general developmental process of interneurons from the angles of the spatial and temporal specifications was presented. Then, the distinct features shown exclusively in OB interneurons development and molecular machinery recently identified were discussed. Finally, we proposed an evolutionary meaning for the diversity of OB interneurons.