• Communications of Mathematical Education
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• v.33 no.1
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• pp.1-19
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• 2019

This study deals with the case of student-centered discrete mathematics class with cyber lab. First, we provided lecture notes and cyber labs we developed. In particular, discrete mathematics is a course that covers the principles of algorithms. The purpose of this study is to provide students with basic mathematics, aiming to actively participate in the learning process, to improve their abilities and to reach the ultimate goal of student success with confidence. Second, based on interactions, students were able to prepare for the lectures, review, question, answer, and discussion through an usual learning management system of the school. Third, all the students generated materials through one semester, which were reported, submitted, presented and evaluated. It was possible to improve the learning effectiveness through the discussions and implementation of using some easy open source programming language and codes. Our discrete math laboratory could be practiced without any special knowledge of coding. These lecture models allow students to develop critical thinking skills while describing and presenting their learning and problem-solving processes. We share our experience and our materials including lecture note and cyber lab as well as a possible model of student-centered mathematics class that does not give too much of work load for instructors. This study shares a model that demonstrates that any professor will be able to have an individualized, customized, and creative discrete education without spending much of extra time and assistant, unlike previous research.

• Journal of Animal Science and Technology
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• v.60 no.12
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• pp.32.1-32.10
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• 2018

Background: Necdin (NDN), a member of the melanoma antigen family showing imprinted pattern of expression, has been implicated as causing Prader-Willi symptoms, and known to participate in cellular growth, cellular migration and differentiation. The region where NDN is located has been associated to QTLs affecting reproduction and early growth in cattle, but location and functional analysis of the molecular mechanisms have not been established. Methods: Here we report the sequence variation of the entire coding sequence from 72 samples of cattle, yak, buffalo, goat and sheep, and discuss its variation in Bovidae. Median-joining network analysis was used to analyze the variation found in the species. Synonymous and non-synonymous substitution rates were determined for the analysis of all the polymorphic sites. Phylogenetic analysis were carried out among the species of Bovidae to reconstruct their relationships. Results: From the phylogenetic analysis with the consensus sequences of the studied Bovidae species, we found that only 11 of the 26 nucleotide changes that differentiate them produced amino acid changes. All the SNPs found in the cattle breeds were novel and showed similar percentages of nucleotides with non-synonymous substitutions at the N-terminal, MHD and C-terminal (12.3, 12.8 and 12.5%, respectively), and were much higher than the percentage of synonymous substitutions (2.5, 2.6 and 4.9%, respectively). Three mutations in cattle and one in sheep, detected in heterozygous individuals were predicted to be deleterious. Additionally, the analysis of the biochemical characteristics in the most common form of the proteins in each species show very little difference in molecular weight, pI, net charge, instability index, aliphatic index and GRAVY (Table 4) in the Bovidae species, except for sheep, which had a higher molecular weight, instability index and GRAVY. Conclusions: There is sufficient variation in this gene within and among the studied species, and because NDN carry key functions in the organism, it can have effects in economically important traits in the production of these species. NDN sequence is phylogenetically informative in this group, thus we propose this gene as a phylogenetic marker to study the evolution and conservation in Bovidae.

• Korean Journal of Microbiology
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• v.55 no.1
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• pp.69-73
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• 2019

During screening of microbes for compounds having cosmetic benefits, we isolated Marinobacter salarius HL2708#2 from lava seawater on Jeju Island, Republic of Korea. The complete genome sequence was determined. Strain HL27080#2 features a circular chromosome of 4,304,603 bp with 57.21% G+C content and a 244,163 bp plasmid with 53.14% G+C. There were 4,180 protein coding sequences identified, along with 49 transfer RNA and 18 ribosomal RNA noncoding genes. The genome harbored genes for the utilization of alcohol, maltose/starch, and monosaccharide as sole carbon sources. Genes responsible for halophilic characteristics and heavy metal resistance could be annotated, as well as aromatic and alkane hydrocarbons. Contrary to the prior report that M. salarius is negative for nitrate and nitrite reduction, nitrate/nitrite reductase along with nitrate/nitrate transporters and nitronate monooxygenase were evident, suggesting that strain HL2708#2 may be able to denitrify extracellular nitroalkenes to ammonia.

• Korean Journal of Microbiology
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• v.55 no.1
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• pp.74-76
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• 2019

Gram-positive anaerobic bacilli Actinomyces spp. commonly reside on mucosal surfaces of the oropharynx, gastrointestinal tract, and urogenital tract. Here, we first report the draft genome sequence of Actinomyces georgiae KHUD_A1, isolated from dental plaque of a Korean elderly woman. The genome is 2,652,059 bp in length and has a GC content of 68.06%. The genome includes 2,242 protein-coding genes, 9 rRNAs, and 64 tRNA. We identified 157 KHUD_A1 strain-specific genes, including genes encoding CPBP family intramembrane metalloprotease, bile acid: sodium symporter family protein, Txe/YoeB family addiction module toxin and Phd/YefM family antitoxin. The sequence information of A. georgiae KHUD_A1 will help understand the general characteristics of the bacterial species and the genome diversity of the genus Actinomyces.

• Journal of the Korean Society for Library and Information Science
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• v.53 no.1
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• pp.109-132
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• 2019

The purpose of this study is to examine and propose to improve the features of a simple keyword search box and faceted navigations of KOLIS-NET operated by the National Library of Korea. A record group of '2011-2020 (776)' under 'Publication date' facet, out of 3,702 records retrieved from a search of '김훈', were examined. Major findings are as follows: (1) Five facets including 'Format', 'Publication date', 'Subject', 'Language' and 'Country' are used to limit search results only in the first step, and multiple facets cannot be simultaneously used; (2) With 'Publication date' facet formed in the span of ten years, a separate publication year cannot be identified; (3) 'Subject' facet based on KDC limits the results only in broad subject classes without sub-facets; (4) Under 'Format' facet, a special format such as large print texts cannot be identified; (5) Without 'Author' facet, authors cannot be identified; and (6) 'Publication date missing', 'Language missing', and 'Miscellaneous subject' record groups cannot be clicked and displayed, a navigation to-and-fro between a brief list and bibliographic records is not smooth, etc. Therefore an application of multiple facets in all stages of limiting the search result, a construction of sub-facets for 'Publication date' and 'Subject' facets, an accurate description and coding of 'General Material Designation', etc. are suggested to improve KOLIS-NET's faceted navigation.

• Journal of the Korean Society of Marine Environment & Safety
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• v.25 no.1
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• pp.18-26
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• 2019

The Maritime Labour Convention, 2006, (MLC) aimed to ensure decent working conditions for seafarers and entered into force on August 20, 2013. It was considered as the fourth pillar in the maritime sector. This paper evaluates how the MLC has been implemented in the field and what issues were addressed in the shipping industry. To achieve this, statistical analysis was conducted using inspection data of Port State Control (PSC) carried out by the Paris MOU and the Tokyo MOU during 2010-2012 and 2014-2016 for deficiencies under the MLC and International Labour Organization (ILO) No. 147 Convention. This study compared pre-2013 and post-2013 deficiency data according to ship's age, size (gross tonnage) and type. The results showed that, although the deficiencies reported by the Tokyo MOU during 2014-2016 were nearly double those from 2010-2012, the deficiency share against total deficiencies for the Tokyo MOU remained two thirds of those for the Paris MOU. This study suggests that the Tokyo MOU should strengthen its inspection efforts on MLC and ILO should provide clear references, such as guidelines and a unified interpretation for national discretions under the MLC for the purpose of harmonized PSC inspections. Additionally, it would be desirable to consolidate the deficiency coding system for the MLC by deleting the codes for the ILO No. 147 Convention, which was incorporated into the MLC. It would also be beneficial to add new deficiency codes for social security, including seafarers' leave and repatriation.

• Korean Journal of Environmental Biology
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• v.37 no.1
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• pp.72-81
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• 2019

Bisphenol A (BPA), a representative endocrine disrupting chemicals, has adverse effects on growth, development and reproduction in aquatic organisms. The object of this study was to investigate the modulation of antioxidant enzyme-coding genes using quantitative real time RT-PCR (qRT-PCR), enzyme activity and total protein content, to understand oxidative stress responses after exposure to BPA for 48 h in brackish water flea Diaphanosoma celebensis. The BPA ($3mg\;L^{-1}$) significantly upregulated the expression of Cu/Zn-SOD, Mn-SOD, and catalase (CAT) mRNA. Three GST isoforms (GST-kappa, GST-mu, and GST-theta) mRNA levels significantly increased at the rate of $0.12mg\;L^{-1}$ of BPA. In particular, GST-mu showed the highest expression level, indicating its key role in antioxidant response to BPA. SOD activity was induced with a concentration-dependent manner, and total protein contents was reduced. These findings indicate that BPA can induce oxidative stress in this species, and these antioxidants may be involved in cellular protection against BPA exposure. This study will provide a better understanding of molecular mode of action of BPA toxicity in aquatic organisms.

• Korean Journal of Microbiology
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• v.55 no.3
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• pp.313-315
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• 2019

An anaerobic bacterial strain WCF-2 was isolated from cow dung in finding cellulose-degrading bacteria for use as silage additives. Strain WCF-2 showed a higher cellulolytic activity than Cellulosilyticum lentocellum DSM $5427^T$, the closest relative of strain WCF-2 (98.2% of 16S rRNA gene sequence similarity). We sequenced the complete genome of strain WCF-2 and compared it with that of C. lentocellum DSM $5427^T$. The OrthoANI value between the two strains was 97.9% thus strain WCF-2 was identified as C. lentocellum. The genome size of strain WCF-2 was 4,779,774 bp with a G + C content of 34.4%, 4,154 coding genes (CDS), 54 pseudo genes, and 142 RNA genes. Strain WCF-2 harbored seven cellulase genes, five of which showed low similarities with those of C. lentocellum DSM $5427^T$.

• Convergence Security Journal
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• v.19 no.2
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• pp.91-104
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• 2019

In this paper, we present a novel local descriptor, Local Prominent Directional Pattern (LPDP), to represent the description of facial images for gender recognition purpose. To achieve a clearly discriminative representation of local shape, presented method encodes a target pixel with the prominent directional variations in local structure from an analysis of statistics encompassed in the histogram of such directional variations. Use of the statistical information comes from the observation that a local neighboring region, having an edge going through it, demonstrate similar gradient directions, and hence, the prominent accumulations, accumulated from such gradient directions provide a solid base to represent the shape of that local structure. Unlike the sole use of gradient direction of a target pixel in existing methods, our coding scheme selects prominent edge directions accumulated from more samples (e.g., surrounding neighboring pixels), which, in turn, minimizes the effect of noise by suppressing the noisy accumulations of single or fewer samples. In this way, the presented encoding strategy provides the more discriminative shape of local structures while ensuring robustness to subtle changes such as local noise. We conduct extensive experiments on gender recognition datasets containing a wide range of challenges such as illumination, expression, age, and pose variations as well as sketch images, and observe the better performance of LPDP descriptor against existing local descriptors.

• Journal of Broadcast Engineering
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• v.24 no.3
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• pp.463-471
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• 2019

This paper proposes a method for reducing the complexity of LIC (Local Illuminance Compensation) for bi-directional inter prediction. The LIC performs local illumination compensation using neighboring reconstruction samples of the current block and the reference block to improve the accuracy of the inter prediction. Since the weight and offset required for local illumination compensation are calculated at both sides of the encoder and decoder using the reconstructed samples, there is an advantage that the coding efficiency is improved without signaling any information. Since the weight and the offset are obtained in the encoding prediction step and the decoding step, encoder and decoder complexity are increased. This paper proposes two methods for low complexity LIC. The first method is a method of applying illumination compensation with offset only in bi-directional prediction, and the second is a method of applying LIC after weighted average step of reference block obtained by bidirectional prediction. To evaluate the performance of the proposed method, BD-rate is compared with BMS-2.0.1 using B, C, and D classes of MPEG standard experimental image under RA (Random Access) condition. Experimental results show that the proposed method reduces the average of 0.29%, 0.23%, 0.04% for Y, U, and V in terms of BD-rate performance compared to BMS-2.0.1 and encoding/decoding time is almost same. Although the BD-rate was lost, the calculation complexity of the LIC was greatly reduced as the multiplication operation was removed and the addition operation was halved in the LIC parameter derivation process.