• Title/Summary/Keyword: clinical sample

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Randomized Controlled Clinical Trials in the Journal of Oriental Rehabilitation Medicine : A Quantitative and Qualitative Analysis(1) (한방재활의학과학회지에 수록된 무작위대조임상연구의 양적, 질적 분석(1))

  • Lee, Hyeon-Yeop;Heo, Kwang-Ho;Cho, Hyun-Woo;Hwang, Eui-Hyoung;Shin, Mi-Suk;Shin, Byung-Cheul
    • Journal of Korean Medicine Rehabilitation
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    • v.23 no.1
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    • pp.87-100
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    • 2013
  • Objectives : The aim of this study is to assess the quantity and quality of randomized controlled clinical trials(RCTs) published in the journal of oriental rehabilitation medicine(JORM). Methods : After searching RCTs from all the articles published in the JORM from the inception(1991) to Oct, 2012, quantity assessment were made on the study design, sample size, main intervention, intervention versus control design and medical condition. Quality assessment were made on the cochrane risk of bias(RoB) check list. Assessment was performed by 2 independent reviewers and disagreement was discussed based on concensus of all authors. Results : Among the 1013 articles, total 59 RCTs were published. First RCT was published in 1994. 49 RCTs were parallel 2-arm designed. Average sample size was 35.1 per study and 16.3 per arm. The most common medical condition is musculoskeletal disease(30.5%). Quality from cochrane RoB was generally low. Conclusions : Though RCTs published in JORM were increasing, the quality remains low. Researchers should make a effort to follow the RoB checklists and improve the quantity and quality of studies.

Fertilization and Pregnancy Rate of Testicular Sperm Extraction(TESE) with Intracytoplasmic Sperm Injection(ICSI) (고환조직 정자채취술 (TESE)의 정자 상태에 따른 세포질내 정자주입술의 (ICSI)수정률과 임신율)

  • Jun, Jin-Hyun;Kim, Jeong-Wook;Park, Yong-Seog;Lee, Ho-Joon;Seo, Ju-Tae;Lee, Yu-Sik;Son, Il-Pyo;Jun, Jong-Young
    • Clinical and Experimental Reproductive Medicine
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    • v.22 no.2
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    • pp.149-153
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    • 1995
  • In IVF-ET program, intracytoplasmic sperm injection(ICSI) has been performed with testicular sperm extraction(TESE) in case of no normal spermatozoon could be retrieved from the epididymis. We wished to see whether the quality of testicular sperm affect the fertilization and pregnancy rate in TESE-ICSI cycles(n=40). These cycles were classified into three groups by the total number of normal motile spermatozoa(TNMS) in the TESE sample: i) good sperm(GS) group(n=12), TNMS > 10,000; ii) moderate sperm(MS) group(n=19), 1,000 < TNMS < 10,000; iii) poor sperm(PS) group(n=9), TNMS < 1,000. Among 423 injected oocytes, 307(72.6%) oocytes were normally fertilized and 43 zygotes were cryopreserved. The fertilization rates of GS group(79.3%) and MS group(75.9%) were significantly(p<0.005) higher than PS group(60.2%). After the embryo transfer(n=40), clinical pregnancy was obtained in 14 cycles(35.0%) and on-going pregnacy in 13 cycles(32.5%). The clinical and on-going pregnancy rates were similar in each group. From these results it can be concluded that testicular spermatozoa are successfully used with ICSI in IVF-ET program in spite of very poor quality of TESE sample.

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Clinical utility of endoscopic ultrasound-guided tissue acquisition for comprehensive genomic profiling of patients with biliary tract cancer, especially with intrahepatic cholangiocarcinoma

  • Takafumi Yanaidani;Kazuo Hara;Nozomi Okuno;Shin Haba;Takamichi Kuwahara;Yasuhiro Kuraishi;Nobumasa Mizuno;Sho Ishikawa;Masanori Yamada;Tsukasa Yasuda
    • Clinical Endoscopy
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    • v.57 no.3
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    • pp.384-392
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    • 2024
  • Background/Aims: Endoscopic ultrasound-guided tissue acquisition (EUS-TA) is a standard diagnostic method for biliary tract cancer (BTC), and samples obtained in this manner may be used for comprehensive genomic profiling (CGP). This study evaluated the utility of EUS-TA for CGP in a clinical setting and determined the factors associated with the adequacy of CGP in patients with BTC. Methods: CGP was attempted for 105 samples from 94 patients with BTC at the Aichi Cancer Center, Japan, from October 2019 to April 2022. Results: Overall, 77.1% (81/105) of the samples were adequate for CGP. For 22-G or 19-G fine-needle biopsy (FNB), the sample adequacy was 85.7% (36/42), which was similar to that of surgical specimens (94%, p=0.45). Univariate analysis revealed that 22-G or larger FNB needle usage (86%, p=0.003), the target primary lesions (88%, p=0.015), a target size ≥30 mm (100%, p=0.0013), and number of punctures (90%, p=0.016) were significantly positively associated with CGP sample adequacy. Conclusions: EUS-TA is useful for CGP tissue sampling in patients with BTC. In particular, the use of 22-G or larger FNB needles may allow for specimen adequacy comparable to that of surgical specimens.

An Investigational Study of Nursing College Student's Clinical Practice Satisfaction (3년제 간호대학생의 임상실습 만족도에 관한 조사 연구)

  • Kim, Eun-Ha;Oh, Yoon-Hee
    • The Journal of Korean Academic Society of Nursing Education
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    • v.6 no.2
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    • pp.186-198
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    • 2000
  • The purpose of this study was to investigate the factors and the degree of nursing college student's clinical practice satisfaction. The sample consisted of 488 nursing students who had been in the clinical practice experience from 6 junior nursing colleges in Korea. Data for this study was collected from 20 May to 20 June, 2000. Data were analysed by SPSS/PC using frequency, percentage, mean, standard deviation, T-test, one-way ANOVA, and regression. The results of this study are as follows : 1. The highest motive of selecting a nursing science came to be 'having a good prospect for getting a job' (29.3%), major place of the clinical nursing practice was university hospital(46.5%), and the degree of satisfaction about the nursing science was 'relatively satisfied' (43%). 2.The fields that the highest satisfaction of the nursing student's clinical practice were DR(3.25), NR(3.18), ICU(3.11), and OR(3.10). The highest rank of the nursing student's clinical practice satisfaction was 'feels more continuous nursing studying is required after getting a job or pass the RN exam'(4.24). 3. There was significant value between the Grade(2yr, 3yr) and the satisfaction of the clinical practice environment(p<0.001), the clinical practice interpersonal relationship (p<0.001), the clinical practice evaluation (p<0.05), and there was significant value between the satisfaction about the nursing science and the satisfaction of the clinical practice environment(p<0.001), the clinical practice interpersonal relation ship (p<0.05), the satisfation after the clinical practice(p<0.001). 4. There was significant value between 'the opinion of the clinical practice periods' and the satisfaction of the clinical practice place(p<0.05), the clinical practice environment(p<0.001), the clinical practice interpersonal relationship(p<0.001), the satisfation after the clinical practice(p<0.001). 5.The satisfaction of the clinical practice interpersonal relationship influenced on the nursing student's clinical practice satisfaction($R^{2}=.188$). From these results, it is suggested that the higher the satisfaction of the clinical practice interpersonal relationship be like to improve the nursing college student's clinical practice satisfaction.

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Relationship of Locus of Control, Difficulties in Emotion Regulation, and Clinical Practice Stress (간호대학생들의 내·외통제소재, 정서조절곤란 및 임상실습스트레스의 관계)

  • Choi, Yeon-Sook;Lee, Eunju;Lee, Dohyeon
    • The Journal of the Korea Contents Association
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    • v.18 no.1
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    • pp.540-550
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    • 2018
  • The purpose of this study was to investigate the relationship of internal-external control, difficulties in emotion regulation, and clinical practice stress among college nursing students. The study was conducted, based on a sample of 220 students at one college and the data were analyzed using descriptive statistics, t-test, ANOVA, Pearson correlation coefficient and stepwise regression analysis. As a result of correlation analysis, there were significant positive correlation in difficulty of emotion regulation score and clinical practice stress score according to external control score. Factors affecting on clinical practice stress were locus of control, difficulties in emotion regulation, college satisfaction, grade, and religion having explanation rate of 17%. Therefore, to decrease clinical stress among nursing students, Nursing students should be considered the emotion regulation with external control disposition. The results can contribute as a basic data in developing education strategies and clinical adjustment programs for regulating clinical stress with emotion management and adaptation on clinical environment.

ADA Levels in Body Fluids as the Preferred Test to Rule Out Tuberculosis in Limited-resource Settings: Data from a Tertiary Care Hospital in Northern India

  • Rasool, Rafia;Rashid, Gowhar;Mir, Shafat Ahmad;Rather, Tahseen Bilal;Mudassar, Syed
    • Korean Journal of Clinical Laboratory Science
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    • v.54 no.3
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    • pp.167-172
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    • 2022
  • In clinical practice, the diagnosis of tuberculosis (TB) continues to be a challenge. The goal of this study was to evaluate the reliability and impact of adenosine deaminase (ADA) enzyme testing as a biochemical marker in the continued management of suspected tuberculosis in a limited resource setting hospital. The retrospective data were collected from 2018 to 2021 and comprised the results of all ADA test assays done in the laboratory. All types of body fluids received for ADA testing were analyzed. Over the course of two years, 1461 samples for ADA assay testing were received. The average age of the study population was 56.69±11.7 years, with males accounting for the majority of the subjects (55.72%). Pleural fluid (N=817, 55.92%) was the most common type of sample received for the ADA assay. 114 (13.95%) of the 817 pleural fluid samples were found to be positive. A survey was conducted to obtain physician's response regarding reliability on ADA testing. 100% of them reported the supportive role of ADA levels in the workup of patients with suspected tuberculosis. In a limited resource setting, the ADA test, in conjunction with clinical and other laboratory findings, can help physicians to initiate early treatment in hospitals for the benefit of patients.

Analysis of Needs for Clinical Dental Hygienist's Performances Using Borich Needs Assessment and the Locus for Focus Model

  • Yang-Keum Han;An-Na Yeo
    • Journal of dental hygiene science
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    • v.23 no.1
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    • pp.1-12
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    • 2023
  • Background: This study aimed to identify the present level and needs of clinical dental hygienists and to present the Borich needs assessment and the locus for focus model as integrated priorities. Methods: The participants of this study were dental hygienists working in dental clinics (hospitals). The final data of the 194 participants were analyzed using frequency analysis and a paired sample t-test. To analyze the need for clinical dental hygienists to perform work, the Borich priority determination formula was used. The x-y plane consisting of four quadrants was used to analyze the need using the locus for focus model, which helps to determine the priority while showing visual effects. Results: "Scaling" was the highest required level for clinical dental hygienists, and "panorama taking" was the highest present level. The priorities of educational needs were systematically and visually derived from dental hygienists who were currently working through the Borich needs assessment and the locus for focus model for each task performed in the clinical field. Through the priorities of these two models, a total of 13 items appeared in the common high-level area; "oral health care (disability)," "oral health care (systemic disease)," "applying a rubber dam," "professional mechanical tooth cleaning," "root planing," "taking vital signs," "medication counseling," "wire cutting," "removing cement after removing band/bracket," "delivering bracket," "preparing mini-screw implantation," "dental insurance claim," and "patient reception." Conclusion: Based on the results, the department of dental hygiene should maintain and improve the standardized clinical practice curriculum and clinical dental hygienists' practical skills and contribute to the realization of the legal scope of dental hygienists, reflecting the requirements of clinical fields.

Clinical Practice Patterns for Benign Prostatic Hyperplasia: An Online Survey (전립선증식증(Benign Prostatic Hyperplasia)의 한의 임상 진료 현황 조사를 위한 온라인 설문 조사)

  • Ji-soo Baek;Seon-mi Shin;Chung-sik Cho
    • The Journal of Internal Korean Medicine
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    • v.44 no.4
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    • pp.703-725
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    • 2023
  • Objectives: This study investigated Korean medicine doctors' perspectives on clinical practice patterns in the process of developing Korean medicine clinical practice guidelines for benign prostatic hyperplasia. Methods: A questionnaire was developed for Korean medicine doctors. A total of 323 oriental medicine doctors participated in the survey, which was live for a total of 9 days from September 22, 2022, to September 30, 2022. Results: Regarding awareness of treatments for benign prostatic hyperplasia, 63.8% of respondents showed high awareness of Korean medical treatments. However, items such as diagnostic criteria (17.7%), evaluation methods (17.0%), and Western medical treatments (22.9%) showed low recognition rates. In clinical practice, 76.2% of respondents were found to treat five or fewer patients with benign prostatic hyperplasia per month, and the average treatment period was 1 to 3 months for most at 41.2%. Korean medicine doctors diagnosed benign prostatic hyperplasia based on clinical features. The main interventions used were acupuncture, herbal medicine (prescription medicine), and moxibustion. This study has several limitations because of the low response rate for this survey; therefore, the participants are not representative of all Korean medicine doctors. In addition, because the study was conducted broadly on various topics related to benign prostatic hyperplasia, sufficient quality management was not carried out. Further studies that include a larger sample size and more in-depth studies on benign prostatic hyperplasia are needed. Conclusions: It is necessary to develop appropriate and reasonable Korean medicine clinical practice guidelines for benign prostatic hyperplasia.

The Influence of Nursing Practice Environment, Compassion Fatigue and Compassion Satisfaction on Burnout among Clinical Nurses (간호근무환경, 공감피로 및 공감만족이 간호사의 소진에 미치는 영향)

  • Kim, Jui;Lee, Tae Wha
    • Journal of Korean Clinical Nursing Research
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    • v.22 no.2
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    • pp.109-117
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    • 2016
  • Purpose: The purpose of this study was to identify the influence of nursing practice environment, compassion fatigue and compassion satisfaction on burnout among clinical nurses in Korea. Methods: A descriptive crosssectional study was conducted. The sample consisted of 210 clinical nurses from three tertiary hospitals located in Seoul. Measurement instruments included the Korean version of the Practice Environment Scale of Nursing Work Index (K-PES-NWI) and Stamm's professional quality of life (ProQOL). Descriptive statistics, t-test, ANOVA, correlation analysis, and multiple regression were used to analyze the data. Results: Nursing practice environment had moderate negative influence on burnout (r=-.38, p<.001). Compassion fatigue had strong positive influence on burnout (r=.50, p<.001), while compassion satisfaction had strong negative influence on burnout (r=-.61, p<.001). The regression model explained 63% of variance of burnout and the compassion satisfaction was the most influencing factor for nurses' burnout. Conclusion: This study identified nursing practice environment, compassion fatigue and compassion satisfaction as influencing factors for nurses' burnout. Strategies to decrease compassion fatigue, enhance compassion satisfaction and create better nursing practice environment are recommended to decrease nurses' burnout.

Factors Affecting Nursing Performance of Delirium for General Hospital Clinical Nurses (종합병원 간호사의 섬망 간호수행 영향요인)

  • Kim, Ji Yeon;Lee, Eun Ju
    • Journal of Korean Clinical Nursing Research
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    • v.22 no.2
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    • pp.183-193
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    • 2016
  • Purpose: This study was conducted to identify factors affecting nursing performance of delirium among general hospital clinical nurses. Methods: This was a cross-sectional study and conducted from July 20 to July 30 2015, with a sample consisting of 167 registered nurses in three general hospitals. Data were analyzed with SPSS 21.0. Results: Nursing performance of delirium had significant positive correlations with knowledge about delirium (r=.25, p=.001), self-confidence in caring for patients with delirium (r=.45, p<.001) and nursing work environment (r=.29, p<.001). In this study, factors affecting nursing performance of delirium were self-confidence in caring for patients with delirium (${\beta}=.33$, p<.001), nursing work environment (${\beta}=.26$, p<.001), experience in nursing education about delirium(${\beta}=.18$, p=.007) and clinical experience (${\beta}=.18$, p=.007). The factors explained 32% of nursing performance of delirium. Conclusion: This study's results can be used as basic data to develope educational programs related to delirium care through continuing education and to improve work environments in developing strategies to enhance nursing performance for patients with delirium.