• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2009년도 추계학술대회 논문집
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• pp.59-60
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• 2009

• 대한안전경영과학회:학술대회논문집
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• 대한안전경영과학회 2011년도 추계학술대회
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• pp.101-105
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• 2011

• 한국위험물학회지
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• 제3권1호
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• pp.52-58
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• 2015

Since the HF release in 2012 in Korea, it became one of the most significant to evaluate consequence to the vicinity of industry facilities handling hazardous materials. BTX plant is selected to assess off-site risk to check whether the facility satisfies the Chemical Control Law by Korea Government. Accident scenarios were listed using process safety information. The scenarios having effect to the off-site were selected and assessed further according to guideline provided by Korea government. Worst case and alternative scenarios including other interested scenarios were evaluated using ALOHA. Each evaluated scenario was assessed further considering countermeasures. The results showed that the facility handling chloric acid is safe enough and needed no further protections at the moment.

• Korean Chemical Engineering Research
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• 제55권5호
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• pp.600-608
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• 2017

산업현장에서 취급되거나 가공되는 원료의약품 분진의 폭발 위험성은 항상 존재하며, 이로 인한 폭발사고가 자주 발생되고 있다. 본 연구에서는 원료의약품 시료 3종의 분진폭발특성을 측정하였다. 주요 폭발특성 측정값은 록소프로펜산은 평균 입경이 $5.31{\mu}m$이며, $P_{max}$는 8.4 bar, 최소점화에너지는 1 mJ < MIE < 3 mJ이며 최소점화온도는 $550^{\circ}C$이다. 클로피도그렐 캄포르술폰산염은 평균 입경이 $95.63{\mu}m$이며, $P_{max}$는 7.9 bar, 최소점화에너지는 30 mJ < MIE < 100 mJ이며 최소점화온도는 $510^{\circ}C$이었다. 리팜피신은 평균 입경이 $26.48{\mu}m$이며 $P_{max}$는 7.9 bar, 최소점화에너지는 1 mJ < MIE < 3 mJ이며 최소점화온도는 $470^{\circ}C$로 나타났다. 이들 값을 적용하여 폭연지수($K_{st}$)와 폭발지수(EI)의 폭발위험등급을 구하고, 원료의약품 분진의 폭발 위험성을 비교 검토하였다. 그 결과 폭발 위험성은 록소프로펜산과 리팜피신의 폭발등급은 St 2이고 폭발위험등급은 severe이며, 클로피도그렐 캄포르술폰산염의 폭발등급은 St 1이고 폭발위험등급은 strong으로 나타났다.

• 한국시뮬레이션학회논문지
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• 제30권2호
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• pp.49-64
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• 2021

화학·생물(화생) 위험을 초기 단계에 효과적으로 대응하기 위해서는 화생 대응 계획을 체계적으로 발전시켜야 하며, 모델링 및 시뮬레이션은 이를 위한 과학적 수단으로 활용될 수 있다. 그러나 오염 확산 모델링 분야는 많은 발전을 이루고 있으나, 화생 대응 계획을 모의하고 적절성을 분석하는 시뮬레이션 분야는 여전히 초기 단계에 머무르고 있다. 이에 본 논문에서는 화생 오염 탐지, 보호, 제독 등 대응 계획을 과학적으로 모의하기 위한 모델을 제안한다. 먼저 기상 및 지형 조건을 고려하여 예측된 오염 확산 결과를 교전 모델에 반영하는 방법을 제시한다. 이어서 공개된 사상자 예측 기법을 기반으로 전투 모의 개체의 화생 피해를 모의하는 화생 전투 피해 모의 기법을 설계한다. 그리고 화생 위험 탐지·정찰, 제독, 보호 등 화생 위험 대응 계획을 체계적으로 모의하는 과업을 모델링한다. 끝으로 화생 감시소 운용에 의한 오염 탐지의 신속성을 분석하는 한편, 화생 제독소 운용 시 오염 부대 규모와 제독 부대 규모에 따른 제독 소요 시간을 분석함으로써 화생 전투 모의 실험의 가능성을 확인한다. 제안된 모델을 이용하면 향후 군의 화생 방호 체계 및 운용개념에 대한 효과 분석은 물론 재난 방재 및 모의 훈련 분야에서도 일부 활용이 가능할 것으로 기대된다.

• 한국환경보건학회지
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• 제46권4호
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• pp.470-479
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• 2020

Objectives: The Coronavirus Disease 2019 (COVID-19) pandemic has caused the death of 740,000 people around the world as of August 12, 2020. Foot-and-Mouth Disease, Avian Influenza, and African Swine Fever are serious livestock diseases. Government agencies in Korea have provided ingredient information and usage instructions for disinfectants used to counter those infectious diseases. The purpose of this study was to provide information on the chemical ingredients in disinfectant products used against COVID-19 and certain livestock diseases. Methods: We collected information from the Korean government. The Central Disaster Management Headquarters and Central Disease Control Headquarters provided information on disinfectant products used against COVID-19. The Animal and Plant Quarantine Agency of Korea provided information on efficacy-certified disinfectant products for use against selected livestock diseases. Health hazard and environmental hazard information on the ingredients in the disinfectants was collected from the Korea Occupational Safety & Health Agency's Material Safety Data Sheets, and toxicity value information was collected from United States Environmental Protection Agency's CompTox Chemicals Dashboard. Results: There were 76 COVID-19 disinfectant products in use, and the most common ingredients were benzalkonium chloride (51%), alkylbenzyl dimethyl ammonium (30%), and ethanol (3%). There were 216 livestock disease disinfectant products comprised of 89 acidic, 88 oxidic, 30 aldehydic, three alkaline, and six other products. Among the 49 active ingredients used in the disinfectants that were investigated, health and environmental hazard information was provided for many of them, but only 20 chemicals had official toxicological information. Conclusion: Since the disinfectants included numerous chemicals, an understanding of their chemical characteristics could be critical to prevent unintended human or environmental exposure.

• 대한임상독성학회지
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• 제16권1호
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• pp.1-8
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• 2018

Purpose: Extremely hazardous pesticides are classified as World Health Organization (WHO) hazard class Ia. However, data describing the clinical course of WHO class Ia OP (organophosphate) poisonings in humans are very scarce. Here, we compare the clinical features of patients who ingested hazard class Ia OPs. Methods: This retrospective observational case study included 75 patients with a history of ingesting ethyl p-nitrophenol thio-benzene phosphonate (EPN), phosphamidon, or terbufos. The patients were divided according to the chemical formulation of the ingested OP. Data regarding mortality and the development of complications were collected and compared among groups. Results: There were no differences in the baseline characteristics and severity scores at presentation between the three groups. No fatalities were observed in the terbufos group. The fatality rates in the EPN and phosphamidon groups were 11.8% and 28.6%, respectively. Patients poisoned with EPN developed respiratory failure later than those poisoned with phosphamidon and also tended to require longer mechanical ventilatory support than phosphamidon patients. The main cause of death was pneumonia in the EPN group and hypotensive shock in the phosphamidon group. Death occurred later in the EPN group than in the phosphamidon group. Conclusion: Even though all three drugs are classified as WHO class Ia OPs (extremely hazardous pesticides), their clinical courses and the related causes of death in humans varied. Their treatment protocols and predicted outcomes should therefore also be different based on the chemical formulation of the OP.

• Korean Chemical Engineering Research
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• 제59권3호
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• pp.359-365
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• 2021

본 연구에서는 분진의 착화 특성 및 정전기 위험성 평가법을 실험적으로 조사하였다. 착화에너지 시험은 PE(HD), PE(LD), PMMA 분진에 대해 MIKE-3장치를 사용하여 실시하였다. PE (HD)의 경우 약 8 ms의 일정 시간 경과 후에 분진운의 착화 화염이 형성되고, 착화원 중심부에서는 화염 핵이 관찰되지 않았다. 분진의 분산 횟수가 증가함에 따라 정전압이 증가하고 분진 농도에 따른 정전압 발생 증가율은 PMMA, PE(LD), PE (HD) 순으로 가장 높았다. PE(HD) 분진의 분산 조건이 정전압에 미치는 영향을 조사하였으며, 분산 횟수가 많아질수록 정전압이 증가하였고 동일한 분산 횟수에서는 분진 농도가 높아질수록 정전압이 증가하였다. 정전기 착화에 의한 화재폭발사고 예방을 위한 안전 정전압은 PE(HD), PE(LD)-1, PE(LD)-2, PMMA에 있어서 각각 2.58, 44.72, 25.82, 8.16 kV로 추정되었다. 정전압 측정자료를 사용하여 정전기 착화 위험성을 효율적으로 조사하여 최소착화에너지를 추정하는 방법을 제안하였다.

• 한국환경성돌연변이발암원학회지
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• 제22권3호
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• pp.149-156
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• 2002

The detection of many synthetic chemicals used in industry that may pose a genetic hazard in our environment is of great concern at present. Since these substances are not limited to the original products, and enter the environment, they have become widespread environmental pollutants, thus leading to a variety of chemicals that possibly threaten the public health. In this respect, to regulate and to evaluate the chemical hazard will be important to environment and human health. The clastogenicity of 18 synthetic chemicals was evaluated in Chinese hamster lung fibroblast cells in vitro. 4-Chloro-3,5-dimethyl phenol (CAS No. 88-04-0) induced chromosomal aberrations with significance at the concentration of 15.7 $\mu\textrm{g}$/$m\ell$ both in the presence and absence of metabolic activation system. Phenoxybenzene (CAS No. 101-84-8) which is one of the most cytotoxic chemical among 18 chemicals tested revealed no clastogenicity in the range of 0.11-0.43 $\mu\textrm{g}$/$m\ell$ both in the presence and absence of metabolic activation system. From the results of chromosomal aberration assay with 18 synthetic chemicals in Chinese hamster lung cells in vitro, 4-chloro-3,5-dimethyl phenol (CAS No. 88-04-0) revealed weak positive clastogenic results in this study.

• 한국수소및신에너지학회논문집
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• 제28권2호
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• pp.166-173
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• 2017

For commercialization of hydrogen refuelling station (HRS), we need to reduce the clearance distance for jet fire in the real entities in the HRS. Thus, we revisited the current regulations of clearance distance for jet fire in the law. The law in korea has been set up by replica of japan, not by our own scientific basis. Recently, sandia lab developed Hydrogen Risk Assessment Model (HyRAM) tools and we simulated a series of circumstances such as 10 to 850 bar with several leak hole sizes. In 850 bar with 10 mm diameter hole leak cases, it shows $4,981kW/m^2$ at 12 m separation from leak source and $1,774kW/m^2$ at 17 m separation from leak source. In 850 bar with 1 mm diameter leak hole, it shows $0.102kW/m^2$ at 12 m separation and $0.044kW/m^2$ at 17 m separation. Current law may be acceptable with 1 mm hole size with 850 bar.