• Journal of Sensor Science and Technology
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• v.12 no.6
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• pp.249-257
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• 2003

The bio-telemetry technologies, that use the wireless miniaturized telemetry module implanted in the human body and transmits several biomedical signal from inside to outside of the body, have been expected to solve the problem such as the patient's inconvenience and the limit for diagnosis. In the case of transceiver system using the wireless RF transmission method, the method of three-dimensional localization for implantable miniaturized telemetry module is necessary to detect the exact position of disease. A new method for three-dimensional localization using small loop antenna in the implantable miniaturized telemetry module was proposed in this paper. We proposed a method that can accurately determine the position of telemetry module by analyzing the differences in the strength of signal, which is received at each of the small size RF receiver array installed on the body surface.

• Preventive Nutrition and Food Science
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• v.19 no.3
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• pp.164-169
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• 2014

The purpose of the present study was to investigate the short-term effects of a 12-day, soft pellet (SP) diet with a 3-h restricted feeding schedule on caloric intake, body weight, lipid metabolism, and insulin sensitivity. Glucose and insulin levels were measured pre-, mid-, and post-feeding. The SP rats exhibited postprandial hyperglycemia compared to rats fed control pellets (CP). The insulin response of SP rats during a meal was significantly higher than that of CP rats. There were no significant differences in the hepatic triacylglycerol contents and lipogenesis gene mRNA levels of SP and CP rats. However, the hepatocytes of SP rats were slightly hypertrophic. In addition, histological analysis revealed that the pancreases of SP rats had more islet areas than those of CP rats. This study demonstrated that feeding an SP-only diet for 12 days induces glucose intolerance, suggesting that the consumption of absorbable food, like a soft diet, may trigger glucose metabolism insufficiency and lead to life-threatening diseases.

• Reproductive and Developmental Biology
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• v.39 no.2
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• pp.29-36
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• 2015

Pigs are considered an ideal source of human disease model due to their physiological similarities to humans. However, the low efficiency of in vitro embryo production (IVP) is still a major barrier in the production of pig offspring with gene manipulation. Despite ongoing advances in the associated technologies, the developmental capacity of IVP pig embryos is still lower than that of their in vivo counterparts, as well as IVP embryos of other species (e.g., cattle and mice). The efficiency of IVP can be influenced by many factors that affect various critical steps in the process. The previous relevant reviews have focused on the in vitro maturation system, in vitro culture conditions, in vitro fertilization medium, issues with polyspermy, the utilized technologies, etc. In this review, we concentrate on factors that have not been fully detailed in prior reviews, such as the oocyte morphology, oocyte recovery methods, denuding procedures, first polar body morphology and embryo quality.

• Korean Journal of Acupuncture
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• v.28 no.3
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• pp.127-140
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• 2011

Objectives : The aim of this study is to regulate the medical meaning about Kwan [self-denial] which is used by Jeongkyeok [reinforcing the weak body part] and Seungkyeok [consolidating the weak body part while inducing cathartic action of comparatively stronger body part] of Saam Acupuncture in common. Methods : This study generalized the method of understanding 'The Five Viscera Interaction' in Oriental Medicine from the perspective of literature and considering human organs in the medical context. Results and Conclusions : 1. There existed 'The Five Viscera Interaction' theory regulating the correlation between the five viscera headed by "Nankyeong" in the traditional Oriental medicine. The five viscera interaction theory was used as the standard of judging the symptom and the prognosis of a disease in the history of Oriental medicine and further used even as the method of preventing and treating diseases. 2. The treatment included in "Biyebaekyobang", a medical book in the period of Goryeo, can be rated as the most developmental form of medical theory which applied 'the five viscera interaction theory' to clinical treatment. The author of "Biyebaekyobang" managed to break away from the schematism of the five viscera interaction through the method of treating two internal organs using one organ treatment and applying the individually different relations between organs. "Biyebaekyobang" shows close similarities to Saam Acupuncture. 3. The organs handled in Saam Acupuncture has a significance in that it put forward the part which had not been aggressively dealt with in medical history up until then.

• Nutrition Research and Practice
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• v.17 no.4
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• pp.641-659
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• 2023

BACKGROUND/OBJECTIVES: The skin is the outermost organ of the human body and plays a protective role against external environmental damages, such as sunlight and pollution, which affect anti-oxidant defenses and skin inflammation, resulting in erythema or skin reddening, immunosuppression, and epidermal DNA damage. MATERIALS/METHODS: The present study aimed to investigate the potential protective effects of red orange complex H extract (ROC) against ultraviolet (UV)-induced skin photoaging in Skh:HR-2 mice. ROC was orally administered at doses of 20, 40, and 80 mg/kg/day for 13 weeks, along with UV irradiation of the mice for 10 weeks. RESULTS: ROC improved UV-induced skin barrier parameters, including erythema, melanin production, transepidermal water loss, elasticity, and wrinkle formation. Notably, ROC inhibited the mRNA expression of pro-inflammatory cytokines (interleukin 6 and tumor necrosis factor α) and melanogenesis. In addition, ROC recovered the UV-induced decrease in the hyaluronic acid and collagen levels by enhancing genes expression. Furthermore, ROC significantly downregulated the protein and mRNA expression of matrix metalloproteinases responsible for collagen degradation. These protective effects of ROC against photoaging are associated with the suppression of UV-induced phosphorylation of c-Jun NH2-terminal kinase and activator protein 1 activation. CONCLUSIONS: Altogether, our findings suggest that the oral administration of ROC exerts potential protective activities against photoaging in UV-irradiated hairless mice.

• Journal of Information Processing Systems
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• v.5 no.2
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• pp.77-86
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• 2009

In this paper, we propose a framework for the real-time monitoring of wireless biosensors. This is a scalable platform that requires minimum human interaction during set-up and monitoring. Its main components include a biosensor, a smart gateway to automatically set up the body area network, a mechanism for delivering data to an Internet monitoring server, and automatic data collection, profiling and feature extraction from bio-potentials. Such a system could increase the quality of life and significantly lower healthcare costs for everyone in general, and for the elderly and those with disabilities in particular.

• Journal of the Korean Society of Clothing and Textiles
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• v.36 no.11
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• pp.1186-1196
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• 2012

This study investigated the garments of middle-aged women undergoing menopause and their satisfaction with them. Data were collected through a survey of 288 middle-aged women and analyzed using SPSS 17.0. As a result (in terms of degree of symptoms) backache, arthralgia, muscular pain and heat sensation were indicated as significantly more outstanding in the menopause group rather than the menopausal transition group. As a countermeasure to physiological symptoms, a change of temperature (warming or cooling) was applied for backache and arthralgia as well as taking medicine for stomachaches and muscular pain. Body parts suffering from heat sensations were the face, back neck, chest center, waist and hip. Body parts suffering from arthralgia and muscular pain were the shoulder and hip joints. The most significant purchasing factor for menopausal women was the fit of outerwear and antibiosis in underwear; however, women not undergoing menopause selected comfortableness when moving as the most important factor. In terms of body shaping and thermoregulation function, the satisfaction degree in underwear was significantly different between the two groups. Menopausal women wanted functional underwear that provided functions such as thermoregulation, absorption of secretions, and antibiosis.

• YAKHAK HOEJI
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• v.41 no.3
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• pp.328-334
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• 1997

Pharmacokinetics of DWP401, a recombinant human epidermal growth factor (rhEGF), was studied using radioimmunoassay (RIA) and $^{125}I$-DWP401 in rats. When DWP401 was adm inistered i.v. at doses of 50 and 500 mcg/kg, the plasma DWP401 disappeared biiexponentially with terminal half life of 4.7 and 92.8 min. The $C_{max}$ and $T_{max}$ after s.c. administration of ti at doses of 50 and 500 ${\mu}g$/kg were determined to be 23.6 and 17.5 ng/ml at 50 ${\mu}g$/kg, and 261.4 ng/ml and 36.8 min, respectively. Both the total urinary and biliary recoveries of intact DWP401 2343 very low (<0.4%), probably due to its extensive degradation in the body. the concentration ratio of DWP401 between the organ and plasma decreased especially in the liver and kidney as the dose and time after the dose increased. For example, the liver/plasma and kidney/plasma concentration ratio of DWP401 at 2.5 min after i.v. doses of 50 ${\mu}g$/kg were comparable and much larger than unity. But, the ratio at 2.5 min after i.v. doses of 500${\mu}g$/kg was much larger in the kidney that in than in the liver. These results suggest that the systemic administration of DWP401 might be subject to rapid and extensive clearance from circulation within several hour after main distrbution to liver and kidney.

• Korean Journal of Applied Biomechanics
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• v.24 no.3
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• pp.259-267
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• 2014

The purpose of this study was to find the relationship between standing posture biomechanics and physical fitness in the elderly. Physical fitness variables and postural variables for 227 (140 women and 87 men) elderly individuals were tested. Physical fitness tests (Korean Institute of Sports Science, 2012) included 3m sit, walk, and return, grip test, 30 second chair sit and stand, sit and reach, figure 8 walks, and 2 minute stationary march. Postural biomechanics variables included resting calcaneal stance position (RCSP), shoulder slope, pelvic slope, knee flexion angle, leg length difference, thoracic angle, and upper body slope. In statistical analysis, multiple regression was conducted by using stepwise selection method via SAS (version 9.2). Analysis for both men and women revealed significant relationships between physical fitness and age, upper body slope, knee flexion angle, leg length difference. Pelvic and thoracic angle were only related to figure 8 walking and sit and reach in women, while RCSP and shoulder slope had no relationship with any physical fitness variables.

• Journal of radiological science and technology
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• v.43 no.4
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• pp.259-264
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• 2020

Radiation causes radiation hazards in the human body. In Korea, a case of radiation necrosis occurred in 2014. In this study, the scatter and shielding efficiency according to lead shielding were classified into epidermis and dermis for 0.511 MeV used in nuclear medicine. In this study, experiments were conducted using the slab phantom that represents calibration and the dose of human trunk. Experimental results showed that the shielding rate of 0.25 mmPb was 180% in the epidermis and 96% in the dermis. Shielding at 0.5mmPb showed shielding rates of 158%in the epidermis and 82% in the dermis. As a result of measuring the absorbed dose by subdividing the thickness of the dermis into 0.5 mm intervals, when the shielding was carried out at 0.25 mmPb, the dose appeared to be about 120% at 0.5 mm of the dermis surface, and the dose was decreased at the subsequent depth. Shielding at 0.5 mmPb, the dose appeared to be about 101% at the surface 0.5 mm, and the dose was measured to decrease at the subsequent depth. This result suggests that when lead aprons are actually used, the scattering rays would be sufficiently removed due to the spaces generated by the clothes and air, Therefore, the scattered ray generated from lead will not reach the human body. The ICRU defines the epidermis (0.07), in which the radiation-induced damage of the skin occurs, as the dose equivalent. If the radiation dose of the dermis is considered in addition, it will be helpful for the evaluation of the prognosis for radiation hazard of the skin.