• KSII Transactions on Internet and Information Systems (TIIS)
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• v.9 no.5
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• pp.1768-1789
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• 2015

The maximal signal-to-interference-plus-noise ratio (Max-SINR) algorithm for interference alignment (IA) has received considerable attention for its high sum rate achievement in the multiple-input multiple-output (MIMO) interference channel. However, its complexity may increase dramatically when the number of users approaches the IA feasibility bound, and the number of iterations and computational time may become unacceptable. In this paper, we study the properties of the Max-SINR algorithm thoroughly by presenting theoretical insight into the algorithm and by providing the potential of reducing the overall computational cost. Furthermore, a novel IA algorithm based on the principle direction search is proposed, which can converge more rapidly than the conventional Max-SINR method. In the proposed algorithm, it searches along the principle direction, which is found to approximately point to the convergence values, and can approach the convergence solutions rapidly. In addition, the closed-form solution of the optimal step size can be formulated in the sense of minimal interference leakage. Simulation results demonstrate that the proposed algorithm outperforms the conventional minimal interference leakage and Max-SINR algorithms in terms of the convergence rate while guaranteeing the high throughput of IA networks.

• Journal of Microbiology and Biotechnology
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• v.2 no.2
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• pp.85-91
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• 1992

The intestinal microflora of humans is an extraordinarily complex mixture of microorganisms, the majority of which are anaerobic microorganisms. The distribution of amylolytic microorganisms in the human large intestinal tract was investigated in various individuals of differing ages using anaerobic culture techniques. A large percentage of the amylolytic microorganisms present belonged to the Genus Bifidobacteria. The number of Bifidobacteria increased significantly at two years of age. Adults and children above 2 years old carried about $0.8{\times}10^9-2.0{\times}10^{10}$ colony forming units (CFU/gram) of amylolytic Bifidobacteria. Among these amylolytic Bifidobacteria, Int-57 was chosen for further studies. Between 65% and 85% of the amylase produced was secreted and the remaining amylase was bound to the cell wall facing the outside. Amylase production could be induced by starch in a stable form. When cells were grown on maltose or glucose, amylase production was much lower than on starch and amylase activity disappeared after 24 hours growth on these media. Partially purified enzymes showed optimum activity at a temperature of $50^{\circ}C$ and at an optimum pH of 5.5, respectively. Heat treatment at $70^{\circ}C$ for 30 minutes almost completely inactivated amylase. The hydrolysis products of starch were mainly maltose and maltotriose. Soluble starch, amylose, amylopectin, and $\gamma$-cyclodextrin($\gamma$-CD) were easily hydrolyzed. The rate of hydrolysis of $\alpha$-CD and $\beta$-CD was slower than that of $\gamma$-CD. Carboxymethyl cellulose, $\beta$-1, 3-glucan and inulin were not hydrolyzed.

• Journal of Life Science
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• v.24 no.1
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• pp.14-19
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• 2014

Kinesin-1 consists of two heavy chains (KHCs), also called KIF5s, and two light chains (KLCs) that form a heterotetrameric complex. Here, we demonstrate the binding of a neuronal KHC, KIF5A, to the carboxyl (C)-terminal tail region of Fig4 (also known as Sac3), a phosphatase that removes the 5-phosphate from phosphatidylinositol-3,5-bisphosphate ($PtdIns(3,5)P_2$). Fig4 bound to the C-terminal region of KIF5A but not to other KHCs (KIF5B and KIF5C) and KLC1 in yeast two-hybrid assays. The interaction was further confirmed in a glutathione S-transferase pull-down assay and by co-immunoprecipitation. Anti-KIF5A antibody co-immunoprecipitated Fig4 with KIF5A from mouse brain extracts. These results suggest that kinesin-1 could transport the Fig4-associated protein complex or cargo in cells.

• Molecules and Cells
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• v.43 no.8
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• pp.694-704
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• 2020

HslUV is a bacterial heat shock protein complex consisting of the AAA+ ATPase component HslU and the protease component HslV. HslV is a threonine (Thr) protease employing the N-terminal Thr residue in the mature protein as the catalytic residue. To date, HslUV from Gram-negative bacteria has been extensively studied. However, the mechanisms of action and activation of HslUV from Gram-positive bacteria, which have an additional N-terminal sequence before the catalytic Thr residue, remain to be revealed. In this study, we determined the crystal structures of HslV from the Gram-positive bacterium Staphylococcus aureus with and without HslU in the crystallization conditions. The structural comparison suggested that a structural transition to the symmetric form of HslV was triggered by ATP-bound HslU. More importantly, the additional N-terminal sequence was cleaved in the presence of HslU and ATP, exposing the Thr9 residue at the N-terminus and activating the ATP-dependent protease activity. Further biochemical studies demonstrated that the exposed N-terminal Thr residue is critical for catalysis with binding to the symmetric HslU hexamer. Since eukaryotic proteasomes have a similar additional N-terminal sequence, our results will improve our understanding of the common molecular mechanisms for the activation of proteasomes.

• Korean Journal of Logic
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• v.21 no.2
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• pp.231-268
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• 2018

Wittgenstein asserts in the Tractatus Logico-Philosophicus 5.542 that "A believes that p" is of the form "'p' says p" and "here we have no co-ordination of a fact and an object, but a co-ordination of facts by means of a co-ordination of their objects." What does, then, it mean exactly that 'p' says p? What are "facts" and "a co-ordination" in the expression "a co-ordination of facts"? Are propositional attitude statements significant propositions or not? Furthermore, what is the point of Wittgenstein's criticism of Russell's theory of judgement? In this paper, I will answer these questions on the basis of Wittgenstein's explication of the concept of thought and Ramsey's relevant remark on propositional attitude. Meanwhile propositional attitude statements are bound up with solipsism of the Tractatus Logico-Philosophicus and some of them have senses. Hence both of assertions that all the propositional attitude statements are significant and all of them are nonsense in the Tractatus Logico-Philosophicus are not correct.

• Journal of Microbiology and Biotechnology
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• v.23 no.7
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• pp.1023-1030
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• 2013

Lipoteichoic acid (LTA), uniquely expressed on gram-positive bacteria, is recognized by Toll-like receptor 2 (TLR2) on not only antigen-presenting cells but also activated T cells. Therefore, it is reasonable to assume that LTA is acting on T cells. However, little is known about the effect of LTA on T-cell regulation. In the present study, we investigated the immunomodulatory effects of LTA on $CD4^+$ T cells. Effector $CD4^+$ T cells, induced after co-culture with S. aureus-pulsed dendritic cells, produced high levels of interferon-${\gamma}$, CD25, CD69, and TLRs 2 and 4. When effector $CD4^+$ T cells were treated with LTA, the expressions of the membrane-bound form of transforming growth factor (TGF)-${\beta}$ and forkhead box P3 increased. Coincidently, the proliferation of effector $CD4^+$ T cells was declined after LTA treatment. When TGF-${\beta}$ signaling was blocked by the TGF-${\beta}$ receptor 1 kinase inhibitor, LTA failed to suppress the proliferation of effector $CD4^+$ T cells. Therefore, the present results suggest that LTA suppresses the activity of effector $CD4^+$ T cells by enhancing TGF-${\beta}$ production.

• The Journal of the Convergence on Culture Technology
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• v.6 no.2
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• pp.299-304
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• 2020

This paper considers the research content and its historical significance of the Study of Nature conducted by John Ruskin(1819-1900) who had a profound influence on art, architecture, social reformation, and preservation of natural environment in Great Britain. Because Ruskin's Study of Nature would be the key to understand totally the implicative meaning of his various academic trials for integrating a wider contexts among human, culture, and society, without being bound by the rules of conventional disciplines. For Ruskin, 'Nature' is defined as 'a system' governing every aspects of human and non-human beings, formulating certain laws of composition. This system has an ecological quality to form a state of harmony by internal interaction and process. Such organic quality of nature worked as 'a metaphor' in Ruskin's research practices. Therefore, Ruskin's Study of Nature would be the conceptual basis for organizing and connecting its various elements of Ruskin's spiritual world.

• Journal of Digital Convergence
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• v.12 no.5
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• pp.451-458
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• 2014

The purpose of this paper is to examine website information as well as promotional texts comparing source texts of Korean with translated versions of English, and drew characteristics of tourism texts from a discourse and communicative perspective. This study shows that the website or promotional texts is the first source of information in tourism, which is most referred to by the in-bound tourists, and the information given by the official homepage is most trustful content of Korean tourism. With comparison of source text of Korean with the translated English version, this paper shows that Korean source texts have a tendency to prefer the longer explication and more detailed information on the scenic spots and attractions than the English translations. When it is translated into English, the translated version does not follow the literal way of translation, and is segmented for reader's understanding and adapted following the target language's communicative conventions and the target culture. Consequently, this study supports the adaption in tourism promotional English translation, and ensures that the communicative constraints of tourism, that is, politeness and Grician maxims are preserved even in the written form of communication, translation.

• Journal of Intelligence and Information Systems
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• v.12 no.2
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• pp.99-123
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• 2006

In an effect to composite an optimal supply chain, this study has introduced an agent-based negotiation as a method to assign a lot of orders to a large number of participants. As a resources allocation mechanism to form a strategic cooperation based on information sharing between supply chain members(buyers, manufacturers, suppliers), this agent negotiation provides coordination functions allowing all participants to make a profit and accomplishing Pareto optimum solution from the viewpoint of a whole supply chain. A SET model-based scheduling takes into consideration both earliness production cost and tardiness production cost, along with a competitive relationship between multiple participants. This study has tried to prove that the result of an agent-based negotiation is a Pareto optimal solution under the dynamic supply chain environment, establishing the mathematical formulation for a performance test, and making a comparison with the heuristic Branch & Bound method.

• Journal of the Korean Institute of Landscape Architecture
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• v.26 no.4
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• pp.25-35
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• 1999

This thesis is to newly understand the value and the meaning of Chonju Palkyong(全州八景) by the specific gravity in making a counter-proposal in other to improve the landscape identity of modern city and at the same time. I intended to group the grafting device for the preservation and regeneration of modern history cultural environment through the interpretation of landscape construction. The meaning system of Chonju Palkyong showed the symbolic system which a landscape construction, four directions and two places has and exhibited the landscape shape possessing a luxuriant local feature peculiar to Chonju, preserving visual bound language of a classical Palkyong. Especially, it implies the use of the substantial landscape experienced factor, the expressions about natural phenomena and the matter which has melted human living circumstances. The landscape construction and it's form show the system which forms the different time field, a far landscape and a mid distance landscape and a near landscape, etc., under the visual, psychological, scenic influenced area, preserving the feature of the similar and typical type of Sosang Palkyoung（瀟湘八景) which intended to seek the local reappearance of the famous site experienced type and natural matter which famous place and local conduct were combined. The object space of Chonju Palkyong area representing the nature of historical landscape cultural assets, pushed by the greater part of the development based theory, shows injured aspects, but needs to play a part to seek such a up-to-date successive plan as the reconstruction of the destroyed historical landscape area which motivated Palkyong, the establishment of useful area, the embodiment of the cultural identity of Palkyong area and the becoming of the educational cultural life space. The analysis of the landscape construction of Chonju Palkyong and the grouping of the modern successive plan which I considered in this thesis, will be able to become a fundamental data to carry out the preservation of historical landscape and the landscape plan in the city.