• 한국임상수의학회지
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• 제36권4호
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• pp.219-224
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• 2019

The aim of this study was to evaluate the safety and effects of a soy lecithin-based supplement on the general health, skin condition, and blood lipid levels of dogs. Twenty-five, healthy, privately-owned dogs were enrolled in the study. Oral supplementation was administered for 8 weeks in the treatment group. Evaluation items included a thorough physical examination, owner responses to a questionnaire, blood analysis (CBC, CRP, serum chemistry, lipid profile). The results showed a significant improvement in amount of exercise, water intake, skin exfoliation in the treatment group (P < 0.05) but no significant changes in the other evaluation items, including no significant changes in blood component results following administration of the supplement. Most dogs well tolerated the treatment, and there were no serious adverse events. We suggest that soy lecithin has potential as a nutraceutical for the positive effect of general health condition such as activity and skin condition. Further studies are needed to establish the appropriate dose level and administration frequency of soy lecithin in dogs.

• 농업과학연구
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• 제49권3호
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• pp.441-450
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• 2022

This study explored the effects of milk flavor (MF) supplementation on growth efficiency, nutrient absorption, fecal score, and blood profiles in weaning piglets. A total of 80 (21 days old) crossbred ([Yorkshire × Duroc] × Landrace) healthy weaned piglets with an initial body weight (BW) of 7.05 ± 1.22 kg were randomly allotted to one of two nutritive treatments with 8 repetitions and five pigs (2 female and 3 male) per pen. The experiment was divided into 2 phases (d 0 - 21, and d 21 - 42), and the dietary treatments consisted of TRT1, basal diet, TRT2 and basal diet + 1.0 g·kg^-1 MF. At days 21 - 42 and the overall period, the average daily gain (ADG) and average daily feed intake (ADFI) increased (p < 0.05) by receiving the MF added feed. However, MF inclusion did not impact (p > 0.05) the feed efficiency (G : F) throughout the entire experiment. Piglets consuming the MF supplemented diet showed that the apparent total tract digestibility of dry matter (DM), nitrogen (N) and energy (E) did not vary significantly (p > 0.05) between the treatments. All through the experiment, the fecal score and blood profile of the piglets fed the flavor diet also remained unaffected (p > 0.05). In conclusion, MF addition to the diet of the piglets increased their body weight and had no adverse effects on nutrient utilization, fecal score, and blood profile. Thus, MF addition could improve the performance outcomes of weaning piglets.

• Animal Bioscience
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• 제35권8호
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• pp.1215-1222
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• 2022

Objective: A feeding trial was carried out to determine the effect of dietary inclusion of silymarin seed extract on growth performance, nutrient digestibility, excreta microbiota, excreta gas emission, blood profiles, and meat quality in broilers. Methods: A total of 1,088 one-day-old Ross 308 broiler chicks (mixed-sex) with an initial body weight of 42.34±0.82 g, were randomly allocated into 1 of 4 dietary treatments with 17 replicates of 16 chicks per cage and fed a basal diet supplemented with 0%, 0.02%, 0.04%, and 0.06% of silymarin. Results: The inclusion of silymarin supplementation linearly increased the body weight of broilers during days 7 to 21 and 1 to 35 days. On day 35, broilers fed a diet containing graded levels of silymarin supplementation linearly increased the nutrient digestibility of dry matter, gross energy, and nitrogen and cecal Lactobacillus counts (p = 0.038). While silymarin supplement linearly reduced the methyl mercaptans (p = 0.039) and acetic acid (p = 0.007) emission in broilers. No significant effects were observed on the blood profile. Relative weights of organs such as breast muscle, bursa of fabricius were increased (linear effect, p<0.05), water holding capacity was enhanced by increasing the silymarin level from 0% to 0.06%. A linear reduction (p>0.05) in drip loss from meat samples during days 1, 3, 5, and 7 by the addition of graded level of silymarin to the diet. Conclusion: An increasing level of silymarin supplementation to the diet of broiler would be beneficial to enhance growth performance, nutrient digestibility, excreta microflora, blood profile, and meat quality traits.

• Animal Bioscience
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• 제36권1호
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• pp.84-97
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• 2023

Objective: One hundred hybrid male ducks (Mojosari×Alabio) were used to examine the efficacy of chicory supplementation as nutritional feed manipulation on production performance, and blood lipid profile of hybrid ducks. Methods: The ducks were tagged, weighed, and then allotted randomly to one of the four treatment diets using a completely randomized design. The experimental diets were: i) P0 (100% basal diets+0% chicory as control), ii) P1 (95% basal diets+5% chicory), iii) P2 (90% basal diets+10% chicory) and iv) P3 (85% basal diets+15% chicory). For each treatment group, there were 5 replicates of 5 birds each. All experimental diets were isonitrogenous and isocaloric using locally available ingredients. Results: Hybrid ducks with fed diets supplemented fresh chicory (5%, 10%, and 15%) showed increased feed intake and body weight gain, as well as feed conversion ratio to be smaller than those ducks fed diets without chicory supplementation (control). The ducks fed 10% chicory supplementation contained significantly (p<0.05) lower ash and higher organic matter contents of meat than those ducks fed other diets. The ducks fed 15% chicory supplementation showed the lowest crude protein and cholesterol content of meat among the treatment diets. Ducks fed chicory supplementation showed lower (p<0.05) blood cholesterol and triglyceride levels than those ducks fed without chicory supplementation, while dietary interventions had no major (p>0.05) influence on low-density lipoprotein and high-density lipoprotein levels in duck blood. Conclusion: In this study, 10% chicory supplementation showed the best results characterized by an increase in growth performance, carcass quality, small intestinal histomorphology, and lower cholesterol levels of meat.

• Journal of Nutrition and Health
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• 제40권4호
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• pp.327-333
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• 2007

The present study was carried out to evaluate the physiological effects of mushroom supplementation on blood glucose levels, lipid profile, and antioxidant enzyme activities in subjects with type 2 diabetes mellitus. Subjects were randomized into either a control group or mushroom supplementation group. Mushroom supplementation was provided 3 times a day for 4 weeks. We found that total dietary fiber intake was about 2.5 times higher (30.3 g vs. 12.3 g) in subjects receiving mushroom supplementation than in the control group. Two groups maintained the same food intake and amount of activity, exercise during the supplementation. We observed no difference in age, height, weight, BMI (body mass index), blood pressure between the groups. Nutrient intake did not differ appreciably between the two groups, except for fiber intake, during the supplementation. Fasting blood glucose levels and 2-hour postprandial blood glucose levels were significantly lower in those ingesting mushroom than in controls. Furthermore, the concentrations of low-density lipoprotein cholesterol were decreased significantly in the mushroom supplementation group. Small changes were observed in the concentration of total cholesterol, triglyceride, high-density lipoprotein cholesterol of those supplemented with mushroom, but these changes were not statistically significant. Activities of superoxide dismutase and catalase with mushroom supplementation were higher than in controls, but and glutathione peroxidase activity was not affected. The levels of thiobarbituric acid reactive substance of mushroom group were lower than control group, but were not significant. We conclude that addition of mushroom influences glycemic control and may be effective in lowering blood lipids and improving antioxidant enzyme activities. Accordingly, such effects may reduce risk factors for cardiovascular disease in patients with type 2 diabetes. However, to confirm these effects and to make dietary recommendations for patients with type 2 diabetes, further studies are necessary.

• 한국식품영양과학회지
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• 제44권10호
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• pp.1415-1421
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• 2015

팽화홍삼 분말 및 음료 식이가 당뇨 유발쥐의 혈당 및 혈청 지질에 미치는 영향을 조사하였다. 홍삼식이는 흰쥐용 기본사료(AIN-93 diet)에 팽화홍삼 분말을 각각 0.3%와 0.6%의 중량비율(w/w)로 첨가하여 실험식이를 제조하였고, 팽화홍삼 음료는 팽화홍삼을 각각 0.14%와 0.28%의 중량비율로 음용수에 희석하여 제조하고 6주 동안 급여하였다. 시험 대조군은 당뇨 유발쥐에게 일반식이(AIN-93 diet)와 물을 급여하였다. 시험기간 동안 주별 혈당의 누적 감소치는 팽화홍삼 분말 B군(0.6%)과 팽화홍삼 음료 C군(0.14%)에서 각각 18.3, 15.1 mg/dL였고, 기준 혈당 대비 시험종료일의 혈당 감소율은 팽화홍삼 분말 B군이 37.4%, 다른 팽화홍삼투여군(A, C, D)에서는 각각 19.2, 18.7 및 17.3%로 비슷하였다. 본 연구 결과 팽화홍삼 투여군은 대조군에 비해서 실험기간 동안 혈당치의 감소에 영향을 미친 것으로 나타났고, 특히 팽화홍삼 분말 B군의 식이를 통한 사포닌 섭취량과 체중 증가, 식이효율 및 음수량 등을 고려할 때 팽화홍삼이 혈당치의 감소에 유의적인 효과를 미친 것으로 사료되었다. 이와 더불어 향후 팽화홍삼의 혈당 감소와 관련된 biomarker에 대한 보다 정밀한 연구가 필요한 것으로 사료된다.

• 대한간호학회지
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• 제41권3호
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• pp.344-353
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• 2011

Purpose: The purpose of this study was to compare the quality of sleep with the serum lipid profile in patients who have restless legs syndrome (RLS). Methods: The data were obtained from 116 patients with RLS through questionnaires and blood sampling. Results: The results of this study showed correlations between lower quality of sleep and serum lipid profile (LDL Cholesterol) in patients with RLS (r=.19, p=.040). There were correlations for scores of quality of sleep from the, Pittsburgh Sleep Quality Index (PSQI) sub-region between lower subjective sleep quality and serum lipid profile (LDL Cholesterol) (r=.20, p=.026), between fewer hours of sleep duration and serum lipid profile (Total Cholesterol) (r=-.21, p=.024), and, between higher daytime dysfunction and serum lipid profile (LDL Cholesterol) (r=.42, p<.001) of patients with RLS. Conclusion: Pati-ents with RLS have sleep disorders with lower quality of sleep and changes in the serum lipid profile for total cholesterol and LDL cholesterol. That is, patients with RLS have lower quality of sleep and dyslipidemia compared to persons without RLS. Further research is needed to monitor serum the lipid profile in early stage symptoms of midlife adult patients with RLS and especially older women.

• Journal of Nutrition and Health
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• 제40권2호
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• pp.162-171
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• 2007

Obesity is an independent risk factor fur coronary artery disease in the postmenopausal women, which may be mediated by alteration of blood lipid metabolism. We are aimed to evaluate the effects of low energy diet, restriction of high fat foods and exercise education on weight, fat mass and blood lipid profile. Fifteen postmenopausal obese women were studied. Subjects received detailed advice about how to achieve a reduction of weight by a low-energy diet (1,200kcal), restriction of high fat food and increased exercise in every 4 wks during 8 wk. To evaluate the effectiveness for education programs, dietary fat habit and daily nutrient intakes, exercise were tested before and after intervention. Anthropometry, computerized tomography, and blood lipid profile were assessed before and after intervention. According to the nutrition education, energy intake (from 1776.1 ${\pm}$ 28.2 kcal to 1268.7 ${\pm}$ 115.2 kcal, p < 0.001) and percent of energy from fat (21.9%, p < 0.01) were significantly decreased. However, the index of nutritional quality was over 1.0. On the contrary, exercise (from 341.3 ${\pm}$ 222.1 kcal to 569.4 ${\pm}$ 309.8 kcal, p < 0.05) was increased and dietary fat habit scores (from 30.8 ${\pm}$ 5.2 to 36.1 ${\pm}$ 3.0, p < 0.01) were improved. Also, body weight (4.2%, p < 0.001), BMI (4.5%, p < 0.001), body fat mass (3.4%, p < 0.05) and waist to hip ratio (1.1%, p < 0.05) were decreased. Among abdominal fat, visceral fat (26.1%, p < 0.05) and subcutaneous fat (14.8%, p < 0.01) were decreased. But there was no difference in visceral fat to subcutaneous fat ratio. We observed HDL-cholesterol increase (11.7%, p < 0.05), triglyceride reduction(14.8%, p < 0.05) and atherogenic index improvement (from 2.7 ${\pm}$ 0.7 to 2.3 ${\pm}$ 0.7, p < 0.05) However, there was no change in LDL-cholesterol and total cholesterol. Theses results showed that low energy diet, restriction of high fat foods and exercise education could result in reduction of body weight, fat mass, visceral and subcutaneous fat, and in improvement of blood lipid profile in the postmenopausal obese women.

• 농업과학연구
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• 제44권1호
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• pp.60-66
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• 2017

This study was conducted to investigate the influence of bone boiling duration on bovine bone extract supplement quality in terms of growth performance, leg bone length, and blood profile in broilers. A total of twenty ROSS 308 broilers (initial BW of $970{\pm}50g$) were randomly divided into the following 4 treatment groups: CON (basal water), T1 (1 : 1 ratio water to bone extract boiled for six hours), T2 (1 : 1 ratio water to bone extract boiled for 12 hours), and T3 (1 : 1 ratio water to bone extract boiled for 24 hours). The broilers were allowed free access to the source of fluid or diets. Average daily feed intake (ADFI), average daily gain (ADG), and feed efficiency showed no significant differences among treatments during this experiment. However, broilers fed bone extract boiled for six hours showed a tendency for increased ADG to other treatments (p < 0.17). No significant differences were observed in organ weights (liver, spleen, bursa of fabricius) or blood profiles among the treatments during the experiment, but broilers fed bone extract boiled for six hours showed a tendency for decreased cholesterol, triglycerides, and HDL compared to the control diet. In the case of leg bone length, there were significant difference (p < 0.05) on tibia and femur among treatments. It was concluded that the six hour-boiled bone extract supplementation had beneficial effects on growth performance and blood profile of broilers.

• 한국유기농업학회지
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• 제22권3호
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• pp.483-490
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• 2014

본 연구는 키토산올리고당의 음수 내 급여가 따른 육계의 혈액성상, 면역력 및 항산화효소계에 미치는 영향을 알아보기 위해 1일령 Arbor Acre종 약 2만 8천수를 대조구와 키토산 음수 급여구로 나누어 5주 동안 실시하였다. 육계의 혈액 성상에서 Glucose의 농도는 대조구보다 키토산올리고당 음수 급여구가 유의적으로 감소하였으나, Triglyceride, Total cholesterol, HDL-cholesterol 및 LDL-cholesterol 농도에는 대조구와 키토산올리고당 음수 급여구간에 차이를 보이지 않았고 간 손상에 대한 인자인 GOT농도는 시험구간에 차이가 없었지만 GPT농도는 대조구보다 키토산올리고당 음수 급여구가 유의적으로 감소하였다(P<0.05). 혈액 내 면역글로블린 농도 중, IgG 농도는 대조구와 키토산올리고당 음수 급여구간에 차이가 없었으나, IgM 농도는 대조구보다 키토산올리고당 음수 급여구가 유의적으로 증가하였다(P<0.05). 항산화력과 SOD의 농도는 시험구간에 차이가 없었으며, Catalase와 Glutathione peroxidase의 농도는 대조구보다 키토산올리고당 음수 급여구가 유의적으로 증가하였다(P<0.05). 따라서, 키토올리고당의 음수 급여로 인해 육계의 당대사, 면역기능 및 1차 항산화 효소계의 활성을 증가시켜 육계의 강건성에 영향을 미칠 수 있음을 보여주었다.