Browse > Article
http://dx.doi.org/10.11625/KJOA.2014.22.3.483

Effect of Inclusion of Chitosan-Oligosaccahariede in Drinking Water on the Blood Component Profile, Immunity and Antioxidative Enzyme in Broiler Chickens  

Park, Seong-Bok (국립축산과학원 가축유전자원시험장)
Kim, Sang-Woo (국립축산과학원 가축유전자원시험장)
Kim, Young-Sin (국립축산과학원 가축유전자원시험장)
Na, Chong-Sam (전북대학교 농업생명과학대학 동물생명공학과)
Shim, Kwan-Seob (전북대학교 농업생명과학대학 동물생명공학과)
Publication Information
Korean Journal of Organic Agriculture / v.22, no.3, 2014 , pp. 483-490 More about this Journal
Abstract
The study was conducted to the effect of inclusion of chitosan-oligosaccharide in drinking water on the blood component profile, immunity and antioxidative enzyme of broiler chickens. A total of 28,000 broiler chickens (Arbor Acre) at 1 days of age were fed the commercial diet until 35 days of age, the treatment divided into two treatments, normal control group and chitosan-oligosaccharide in drinking water group. In concentration of glucose, treatment was significantly decreased than control (P<0.05), but not statistically different on the Triglyceride, Total cholesterol, HDL-cholesterol and LDL-cholesterol in the Blood component profile of broiler chicks. The concentration of glutamic oxalacetic transaminase (GOT) was statistically different but the concentration of glutamic pyruvate transaminase (GPT) was significantly decreased in treatment fed chitosan-oligosaccharide than control (P<0.05). Immunoglobullins in the blood, concentration of IgG was not significantly different among control and treatment but concentration of IgM was significantly increased in fed chitosan-oligosaccharide than control (P<0.05). Antioxidant and super oxide dismutase (SOD) was not different among control and treatment and concentration of catalase and glutathione peroxidase were significantly increased in fed chitosan-oligosaccharide than control (P<0.05).
Keywords
chitosan-oligosaccharide; blood component profile; immunity; antioxidative enzyme; broiler;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 Austin, P. R., C. J. Brine, J. E. Castle, and J. P. Zikakis. 1981. Chitin: New facets of research. Science. 212-749.
2 Hossain, S., A. Rahman, Y. Kahir, A. A. Shams, F. Atros, and M. Ilashimoto. 2007. Effect of shrimp-drived chitosan on plasma lipid profile and liver lipid peroxide levels in hypercholesterolaemic rats. Clin. Exp. Phamacol. Physiol. 34: 170-176.   DOI   ScienceOn
3 Jean, Y. J., and S. K. Kim. 2001a. Effect of antimicrobial activity by chitosan oligosaccharides N-conjugated with asparagine. J. Microbiol. Biotechnol. 11: 281-286.
4 Jean, Y. J. and S. K. Kim. 2001b. Potential immune-stimulating effect of antitumoral fraction of chitosan-oligosaccharides. J. Chitin Chitosan. 6: 163-167.
5 Jung, B. Y., I. K. Paik, D. M. Lee, and S. B. Seo. 2004. The effects of a chitosan product supplementation on the performance of broiler breeders, broilers, pigs and dairy cattle. J. Chitin Chitosan. 9: 168-174.
6 Kim, Y. J. and B. K. Kim. 2009. Effect of dietary chitosan supplementation with feeding levels and feeding forms on growth performance and carcass characteristics of thigh muscular in broiler. Korean J. Poult. Sci. 36: 29-37.   DOI
7 Korea Food & Drug Administration. 2010. Chitosan chitooligosaccharide criterion and standard. Cheongwon, Korea.
8 Guha, S., S. K. Pal, N. Chatterjec, G. Sarker, S. Pal, A. K. Basu, and R. Bancrjee. 2005. Effect of chitosan on lipid levels when administered concurrently with atorvastatin-a placebo controlled study. J. Indian. Med. Assoc. 103: 418-421.
9 LeHoux, J. G. and F. Grondin. 1993. Some effects of chitosan on liver function in the rat. Endocrinoloy. 132: 1078-1084.
10 Liu, B., W. S. Liu, B. Q. Han, and Y. Y. Sun. 2007. Antidiabetic effects of chitooligosacchrides on pancreatic islet cells in streptozotocin-induced diabetic rats. World J. Gastroenterol. 13: 725-731.   DOI
11 Mendis, E., M. N. Kim, N. Rajapakse, and S. K. Kim. 2007. An in vitro cellular analysis of the radical scavenging efficacy of chitooligosaccharides. Life Sci. 80: 2118-2127.   DOI   ScienceOn
12 Nam, K. D., H. G. Hahn, S. J. Cho, G. H. Park, and C. T. Kim. 2008. Effects of watersoluble chitosan-based feed additive on growth performance and quality in broiler chickens. J. Chitin Chitosan. 13: 14-22.
13 Nam, K. S., M. S. So, and Y. H. Shon. 2007. Effect of chitosan oligosaccharide on carcinogenesis. J. Chitin Chitosan. 12: 95-98.
14 Razdan, A., and D. Pettersson. 1994. Effect of chitosan on nutrient digestibility and plasma lipid concentration in broiler chicken. Br. J. Nutr. 72: 277-288.   DOI   ScienceOn
15 SAS Instintute. 2000. SAS User's Guide: Statistics. Version 8 edition SAS Institute Inc., Cary, NC, USA.
16 Sumiyoshi, M. and Y. Kimura. 2006. Low molecular weight chitosan inhibits obesity induced by feeding a high-fat diet long-term in mice. J. Pharm. Pharmacol. 58: 201-207.
17 Tanaka, Y., S. I. Tanioka, M. Tanaka, T. Tanigawa, Y. Kitamura, S. Minami, Y. Okamoto, M. Miyashita, and M. Nanno. 1997. Effects of chitin and chitosan particles on BALB/c mice by oral and parenteral administration. Biomaterials. 18: 591-595.   DOI   ScienceOn
18 Yoon, H. J., M. E. Moon, H. S. Park, S. Y. Im, and Y. H. Kim. 2007. Chitosan oligosaccharide (COS) inhibits LPS-induced inflammatory effects in RAW 264.7 macrophage cells. Bio. Chem. Biophys. Res. Commun. 358: 954-959.   DOI   ScienceOn