• Title/Summary/Keyword: biomimetics

Search Result 96, Processing Time 0.036 seconds

Direct Visualization of Temperature Profiles in Fractal Microchannel Heat Sink for Optimizing Thermohydrodynamic Characteristics (온도 프로파일 가시화를 통한 프랙탈 구조 마이크로채널 히트싱크의 열수력학적 특성 최적화)

  • Hahnsoll Rhee;Rhokyun Kwak
    • Journal of the Korean Society of Visualization
    • /
    • v.22 no.1
    • /
    • pp.79-84
    • /
    • 2024
  • As microchips' degree of integration is getting higher, its cooling problem becomes important more than ever. One of the promising methods is using fractal microchannel heat sink by mimicking nature's Murray networks. However, most of the related works have been progressed only by numerical analysis. Perhaps such lack of direct experimental studies is due to the technical difficulty of the temperature and heat flux measurement in complex geometric channels. Here, we demonstrate the direct visualization of in situ temperature profile in a fractal microchannel heat sink. By using the temperature-sensitive fluorescent dye and a transparent Polydimethylsiloxane window, we can map temperature profiles in silicon-based fractal heat sinks with various fractal scale factors (a=1.5-3.5). Then, heat transfer rates and pressure drops under a fixed flow rate were estimated to optimize hydrodynamic and thermal characteristics. Through this experiment, we found out that the optimal factor is a=1.75, given that the differences in heat transfer among the devices are marginal when compared to the variances in pumping power. This work is expected to contribute to the development of high-performance, high-efficiency thermal management systems required in various industrial fields.

Geometric and mechanical properties evaluation of scaffolds for bone tissue applications designing by a reaction-diffusion models and manufactured with a material jetting system

  • Velasco, Marco A.;Lancheros, Yadira;Garzon-Alvarado, Diego A.
    • Journal of Computational Design and Engineering
    • /
    • v.3 no.4
    • /
    • pp.385-397
    • /
    • 2016
  • Scaffolds are essential in bone tissue engineering, as they provide support to cells and growth factors necessary to regenerate tissue. In addition, they meet the mechanical function of the bone while it regenerates. Currently, the multiple methods for designing and manufacturing scaffolds are based on regular structures from a unit cell that repeats in a given domain. However, these methods do not resemble the actual structure of the trabecular bone which may work against osseous tissue regeneration. To explore the design of porous structures with similar mechanical properties to native bone, a geometric generation scheme from a reaction-diffusion model and its manufacturing via a material jetting system is proposed. This article presents the methodology used, the geometric characteristics and the modulus of elasticity of the scaffolds designed and manufactured. The method proposed shows its potential to generate structures that allow to control the basic scaffold properties for bone tissue engineering such as the width of the channels and porosity. The mechanical properties of our scaffolds are similar to trabecular tissue present in vertebrae and tibia bones. Tests on the manufactured scaffolds show that it is necessary to consider the orientation of the object relative to the printing system because the channel geometry, mechanical properties and roughness are heavily influenced by the position of the surface analyzed with respect to the printing axis. A possible line for future work may be the establishment of a set of guidelines to consider the effects of manufacturing processes in designing stages.

Convergence Study on Fabrication and Plasma Module Process Technology of ReRAM Device for Neuromorphic Based (뉴로모픽 기반의 저항 변화 메모리 소자 제작 및 플라즈마 모듈 적용 공정기술에 관한 융합 연구)

  • Kim, Geunho;Shin, Dongkyun;Lee, Dong-Ju;Kim, Eundo
    • Journal of the Korea Convergence Society
    • /
    • v.11 no.10
    • /
    • pp.1-7
    • /
    • 2020
  • The manufacturing process of the resistive variable memory device, which is the based of neuromorphic device, maintained the continuity of vacuum process and applied plasma module suitable for the production of the ReRAM(resistive random access memory) and process technology for the neuromorphic computing, which ensures high integrated and high reliability. The ReRAM device of the oxide thin-film applied to the plasma module was fabricated, and research to improve the properties of the device was conducted through various experiments through changes in materials and process methods. ReRAM device based on TiO2/TiOx of oxide thin-film using plasma module was completed. Crystallinity measured by XRD rutile, HRS:LRS current value is 2.99 × 103 ratio or higher, driving voltage was measured using a semiconductor parameter, and it was confirmed that it can be driven at low voltage of 0.3 V or less. It was possible to fabricate a neuromorphic ReRAM device using oxygen gas in a previously developed plasma module, and TiOx thin-films were deposited to confirm performance.

Artificial Intelligence Art : A Case study on the Artwork An Evolving GAIA (대화형 인공지능 아트 작품의 제작 연구 :진화하는 신, 가이아(An Evolving GAIA)사례를 중심으로)

  • Roh, Jinah
    • The Journal of the Korea Contents Association
    • /
    • v.18 no.5
    • /
    • pp.311-318
    • /
    • 2018
  • This paper presents the artistic background and implementation structure of a conversational artificial intelligence interactive artwork, "An Evolving GAIA". Recent artworks based on artificial intelligence technology are introduced. Development of biomimetics and artificial life technology has burred differentiation of machine and human. In this paper, artworks presenting machine-life metaphor are shown, and the distinct implementation of conversation system is emphasized in detail. The artwork recognizes and follows the movement of audience using its eyes for natural interaction. It listens questions of the audience and replies appropriate answers by text-to-speech voice, using the conversation system implemented with an Android client in the artwork and a webserver based on the question-answering dictionary. The interaction gives to the audience discussion of meaning of life in large scale and draws sympathy for the artwork itself. The paper shows the mechanical structure, the implementation of conversational system of the artwork, and reaction of the audience which can be helpful to direct and make future artificial intelligence interactive artworks.

실리콘 나노와이어의 산소 흡착 표면 처리를 통한 초소수성 구현

  • Seo, Jeong-Mok;Lee, Tae-Yun
    • Proceedings of the Materials Research Society of Korea Conference
    • /
    • 2011.05a
    • /
    • pp.36.2-36.2
    • /
    • 2011
  • 최근 나노기술의 비약적인 발전을 바탕으로 그 동안 구현이 쉽지 않았던 마이크로-나노 단위의 생체모사(biomimetics) 기술이 큰 각광을 받고 있다. 그 중에서도 특히 연잎 효과(lotus-effect)로 대표되는 접촉각 $150^{\circ}$ 이상의 초소수성(superhydrophobicity) 표면 구현은 생물, 화학, 물질 등의 다양한 분야에 있어 큰 사용가치를 가지기 때문에 연구가 전세계적으로 활발히 진행되고 있다. 초소수성을 가지는 표면을 구현하기 위해서는 표면의 화학적인 조성을 변화시켜 표면의 거칠기를 증대시키는 방법과 표면에너지를 낮추는 방법으로 구분될 수 있으며, 이를 위해 표면에 나노구조체를 형성시켜 표면 거칠기를 증대시키는 방법과 silane 계열의 자가-형성 단일막(Self-assembled monolayer)을 코팅하여 표면에너지를 낮추는 방법이 사용되어 왔다. 그러나 표면에 나노구조체를 형성시키는 과정에서 비싼 공정 비용이 발생하며, 대면적 구현이 쉽지 않다는 단점이 있으며, silane 계열의 자가-형성 단일막의 경우에는 제거가 쉽지 않아 추후 다양한 소자에의 적용이 어렵다는 단점을 가지고 있다. 본 연구에서는 무전해 식각법(Aqueous Electroless Etching)을 이용하여 대면적으로 합성시킨 실리콘 나노와이어의 표면 산소 흡착 처리를 통해 $156^{\circ}$ 이상의 초소수성 표면을 구현하였다. 액상 기반으로 형성된 실리콘 나노와이어의 표면은 열처리 공정을 통해 OH-기에서 O-기로 치환되어 낮은 표면에너지를 가지게 되며, 낮아진 표면에너지와 산화과정에서 증대된 표면 거칠기를 통해 Wenzel-state의 초소수성 표면 성질을 보였다. 변화된 나노와이어의 표면 거칠기는 주사전자현미경 (FE-SEM)과 주사투과현미경 (HR-TEM)을 통해 관찰되었다. 또한, 나노와이어의 길이와 열처리 공정 조건에 따라 나노와이어의 표면을 접촉각 $0^{\circ}$의 초친수성(superhydrophilicity) 특성부터 접촉각 $150^{\circ}$ 이상의 초소수성 특성까지 변화시킬 수 있었으며, 나노와이어의 길이에 따라 표면 난반사율을 조절하여 90% 이상의 매우 높은 흡수율을 가지는 나노와이어 표면을 구현할 수 있었다. 이러한 산소 흡착법을 이용한 초소수성 표면 구현은 기존 자가-형성 단일막 코팅을 이용한 방법에 비해 소자 제작 및 활용에 있어 매우 유리하며, 바이오칩, 수광소자 등의 다양한 응용 분야에 적용 가능할 것으로 예상된다.

  • PDF

Latent Transforming Growth Factor-beta1 Functionalised Electrospun Scaffolds Promote Human Cartilage Differentiation: Towards an Engineered Cartilage Construct

  • Lim, Erh-Hsuin;Sardinha, Jose Paulo;Myers, Simon;Stevens, Molly
    • Archives of Plastic Surgery
    • /
    • v.40 no.6
    • /
    • pp.676-686
    • /
    • 2013
  • Background To overcome the potential drawbacks of a short half-life and dose-related adverse effects of using active transforming growth factor-beta 1 for cartilage engineering, a cell-mediated latent growth factor activation strategy was developed incorporating latent transforming growth factor-${\beta}$1 (LTGF) into an electrospun poly(L-lactide) scaffold. Methods The electrospun scaffold was surface modified with NH3 plasma and biofunctionalised with LTGF to produce both random and orientated biofunctionalised electrospun scaffolds. Scaffold surface chemical analysis and growth factor bioavailability assays were performed. In vitro biocompatibility and human nasal chondrocyte gene expression with these biofunctionalised electrospun scaffold templates were assessed. In vivo chondrogenic activity and chondrocyte gene expression were evaluated in athymic rats. Results Chemical analysis demonstrated that LTGF anchored to the scaffolds was available for enzymatic, chemical and cell activation. The biofunctionalised scaffolds were non-toxic. Gene expression suggested chondrocyte re-differentiation after 14 days in culture. By 6 weeks, the implanted biofunctionalised scaffolds had induced highly passaged chondrocytes to re-express Col2A1 and produce type II collagen. Conclusions We have demonstrated a proof of concept for cell-mediated activation of anchored growth factors using a novel biofunctionalised scaffold in cartilage engineering. This presents a platform for development of protein delivery systems and for tissue engineering.

Temperature-responsive bioactive hydrogels based on a multifunctional recombinant elastin-like polymer

  • Santo, Vitor E.;Prieto, Susana;Testera, Ana M.;Arias, Francisco J.;Alonso, Matilde;Mano, Joao F.;Rodriguez-Cabello, Jose Carlos
    • Biomaterials and Biomechanics in Bioengineering
    • /
    • v.2 no.1
    • /
    • pp.47-59
    • /
    • 2015
  • A bioactive and multifunctional elastin-like polymer (ELP) was produced by genetic engineering techniques to develop new artificial matrices with the ability to mimic the extracellular matrix (ECM). The basic composition of this ELP is a thermo- and pH-sensitive elastin pentapeptide which has been enriched with RGD-containing domains, the RGD loop of fibronectin, for recognition by integrin receptors on their sequence to promote efficient cell attachment. Hydrogels of this RGD-containing polymer were obtained by crosslinking with hexamethylene diisocyanate, a lysine-targeted crosslinker. These materials retain the "smart" nature and temperature-responsive character, and the desired mechanical behavior of the elastin-like polymer family. The influence of the degree of crosslinking on the morphology and properties of the matrices were tested by calorimetric techniques and scanning electron microscopy (SEM). Their mechanical behavior was studied by dynamical mechanical analysis (DMA). These results show the potential of these materials in biomedical applications, especially in the development of smart systems for tissue engineering.

Fabrication of High-Aspect-Ratio Microscale Polymer Hairs Having Surface Wrinkles (고 세장비 표면주름을 가진 마이크로 폴리머 헤어 제작)

  • Park, Sang-Hu;Kim, Seong-Jin;Park, Hee-Jin;Lee, Joo-Chul;Shin, Bo-Sung
    • Polymer(Korea)
    • /
    • v.37 no.1
    • /
    • pp.1-4
    • /
    • 2013
  • We proposed a new process to fabricate a high-aspect-ratio microhair having surface wrinkles using the contact-and-tension of a microstamp. Through this work, we observed that regular surface wrinkles were generated on the hair with a diameter of around $20{\mu}m$ due to the uni-directional compressive stress during the photocuring process by ultraviolet light. To do this, we conducted an experimental system setup for contact-and-tension process. From the preliminary test results, we believed that the proposed method can be applied to make a long polymer hair having surface wrinkles for special applications to biomimetics, and some research fields related on surface area such as heat transfer and catalyst enhancement.

Design and Control of a Biomimetic Fish Robot (생체 모방 로봇 물고기의 설계와 제어에 관한 연구)

  • Kim, Young-Jin;Kim, Seung-Jae;Yang, Kyung-Sun;Lee, Jeong-Min;Yim, Chung-Hyuk;Kim, Dong-Hwan
    • Transactions of the Korean Society of Mechanical Engineers A
    • /
    • v.36 no.1
    • /
    • pp.1-7
    • /
    • 2012
  • This paper introduces the mechanical design, fabrication, and control of a biomimetic fish robot whose driving motions resemble a real fish's flexibility and movement. This robot uses two motors create flexible movement like that of a fish. Several schemes, such as neutral buoyancy, fast underwater swimming, and direction changes, are introduced. The tail of the fish robot is made of a polymer material for flexible movement. The interior of the tail contains a joint and a wire. A sine wave command was applied to the tail to produce motion resembling a real fish swimming, and a buoy control device was installed. The up and down motion of the robot fish was controlled using this device.