• Title/Summary/Keyword: biological information processing

Search Result 275, Processing Time 0.033 seconds

Mapping Studies on Visual Search, Eye Movement, and Eye track by Bibliometric Analysis

  • Rhie, Ye Lim;Lim, Ji Hyoun;Yun, Myung Hwan
    • Journal of the Ergonomics Society of Korea
    • /
    • v.34 no.5
    • /
    • pp.377-399
    • /
    • 2015
  • Objective: The aim of this study is to understand and identify the critical issues in vision research area using content analysis and network analysis. Background: Vision, the most influential factor in information processing, has been studied in a wide range of area. As studies on vision are dispersed across a broad area of research and the number of published researches is ever increasing, a bibliometric analysis towards literature would assist researchers in understanding and identifying critical issues in their research. Method: In this study, content and network analysis were applied on the meta-data of literatures collected using three search keywords: 'visual search', 'eye movement', and 'eye tracking'. Results: Content analysis focuses on extracting meaningful information from the text, deducting seven categories of research area; 'stimuli and task', 'condition', 'measures', 'participants', 'eye movement behavior', 'biological system', and 'cognitive process'. Network analysis extracts relational aspect of research areas, presenting characteristics of sub-groups identified by community detection algorithm. Conclusion: Using these methods, studies on vision were quantitatively analyzed and the results helped understand the overall relation between concepts and keywords. Application: The results of this study suggests that the use of content and network analysis helps identifying not only trends of specific research areas but also the relational aspects of each research issue while minimizing researchers' bias. Moreover, the investigated structural relationship would help identify the interrelated subjects from a macroscopic view.

Gel Image Matching Using Hopfield Neural Network (홉필드 신경망을 이용한 젤 영상 정합)

  • Ankhbayar Yukhuu;Hwang Suk-Hyung;Hwang Young-Sup
    • The KIPS Transactions:PartB
    • /
    • v.13B no.3 s.106
    • /
    • pp.323-328
    • /
    • 2006
  • Proteins in a cell appear as spots in a two dimensional gel image which is used in protein analysis. The spots from the same protein are in near position when comparing two gel images. Finding out the different proteins between a normal tissue and a cancer one is important information in drug development. Automatic matching of gel images is difficult because they are made from biological experimental processes. This matching problem is known to be NP-hard. Neural networks are usually used to solve such NP-hard problems. Hopfield neural network is selected since it is appropriate to solve the gel matching. An energy function with location and distance parameters is defined. The two spots which make the energy function minimum are matching spots and they came from the same protein. The energy function is designed to reflect the topology of spots by examining not only the given spot but also neighborhood spots.

Development and Evaluation of D-Attention Unet Model Using 3D and Continuous Visual Context for Needle Detection in Continuous Ultrasound Images (연속 초음파영상에서의 바늘 검출을 위한 3D와 연속 영상문맥을 활용한 D-Attention Unet 모델 개발 및 평가)

  • Lee, So Hee;Kim, Jong Un;Lee, Su Yeol;Ryu, Jeong Won;Choi, Dong Hyuk;Tae, Ki Sik
    • Journal of Biomedical Engineering Research
    • /
    • v.41 no.5
    • /
    • pp.195-202
    • /
    • 2020
  • Needle detection in ultrasound images is sometimes difficult due to obstruction of fat tissues. Accurate needle detection using continuous ultrasound (CUS) images is a vital stage of treatment planning for tissue biopsy and brachytherapy. The main goal of the study is classified into two categories. First, new detection model, i.e. D-Attention Unet, is developed by combining the context information of 3D medical data and CUS images. Second, the D-Attention Unet model was compared with other models to verify its usefulness for needle detection in continuous ultrasound images. The continuous needle images taken with ultrasonic waves were converted into still images for dataset to evaluate the performance of the D-Attention Unet. The dataset was used for training and testing. Based on the results, the proposed D-Attention Unet model showed the better performance than other 3 models (Unet, D-Unet and Attention Unet), with Dice Similarity Coefficient (DSC), Recall and Precision at 71.9%, 70.6% and 73.7%, respectively. In conclusion, the D-Attention Unet model provides accurate needle detection for US-guided biopsy or brachytherapy, facilitating the clinical workflow. Especially, this kind of research is enthusiastically being performed on how to add image processing techniques to learning techniques. Thus, the proposed method is applied in this manner, it will be more effective technique than before.

Design of a 10-bit SAR ADC with Enhancement of Linearity On C-DAC Array (C-DAC Array내 선형성을 향상시킨 10비트 CMOS SAR ADC 설계)

  • Kim, Jeong Heum;Lee, Sang Heon;Yoon, Kwang Sub
    • Journal of the Institute of Electronics and Information Engineers
    • /
    • v.54 no.2
    • /
    • pp.47-52
    • /
    • 2017
  • In this paper, CMOS SAR A/D converter 1.8V supply for the design of an A/D converter having an middle speed for the biological signal processing was designed. This paper proposes design of a 10-bit SAR Analog to Digital Converter improving linearity driven by MSB node of C-DAC array divided into 4 equal parts. It enhances linearity property, by retaining the analog input signal charging time at MSB node. Because MSB node samples analog input, it enhances resolution through getting initial input signal precisely. By using split capacitor on C-DAC array, it reduced chip size and power dissipation. The Proposed SAR A/D Converter is fabricated in 0.18um CMOS and measured 7.5 bits of ENOB at sampling frequency 4MS/s and power supply of 1.8V. It occupies a core area of $850{\times}650um^2$ and consumes 123.105uW. Therefore it results in 170.016fJ/step of FOM(Figure of Merit).

Code Optimization in DNA Computing for the Hamiltonian Path Problem (해밀톤 경로 문제를 위한 DNA 컴퓨팅에서 코드 최적화)

  • 김은경;이상용
    • Journal of KIISE:Software and Applications
    • /
    • v.31 no.4
    • /
    • pp.387-393
    • /
    • 2004
  • DNA computing is technology that applies immense parallel castle of living body molecules into information processing technology, and has used to solve NP-complete problems. However, there are problems which do not look for solutions and take much time when only DNA computing technology solves NP-complete problems. In this paper we proposed an algorithm called ACO(Algorithm for Code Optimization) that can efficiently express DNA sequence and create good codes through composition and separation processes as many as the numbers of reaction by DNA coding method. Also, we applied ACO to Hamiltonian path problem of NP-complete problems. As a result, ACO could express DNA codes of variable lengths more efficiently than Adleman's DNA computing algorithm could. In addition, compared to Adleman's DNA computing algorithm, ACO could reduce search time and biological error rate by 50% and could search for accurate paths in a short time.

Development of HCS(High Contents Screening) Software Using Open Source Library (오픈 소스 라이브러리를 활용한 HCS 소프트웨어 개발)

  • Na, Ye Ji;Ho, Jong Gab;Lee, Sang Joon;Min, Se Dong
    • KIPS Transactions on Software and Data Engineering
    • /
    • v.5 no.6
    • /
    • pp.267-272
    • /
    • 2016
  • Microscope cell image is an important indicator for obtaining the biological information in a bio-informatics fields. Since human observers have been examining the cell image with microscope, a lot of time and high concentration are required to analyze cell images. Furthermore, It is difficult for the human eye to quantify objectively features in cell images. In this study, we developed HCS algorithm for automatic analysis of cell image using an OpenCV library. HCS algorithm contains the cell image preprocessing, cell counting, cell cycle and mitotic index analysis algorithm. We used human cancer cell (MKN-28) obtained by the confocal laser microscope for image analysis. We compare the value of cell counting to imageJ and to a professional observer to evaluate our algorithm performance. The experimental results showed that the average accuracy of our algorithm is 99.7%.

A Survey of Genetic Programming and Its Applications

  • Ahvanooey, Milad Taleby;Li, Qianmu;Wu, Ming;Wang, Shuo
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • v.13 no.4
    • /
    • pp.1765-1794
    • /
    • 2019
  • Genetic Programming (GP) is an intelligence technique whereby computer programs are encoded as a set of genes which are evolved utilizing a Genetic Algorithm (GA). In other words, the GP employs novel optimization techniques to modify computer programs; imitating the way humans develop programs by progressively re-writing them for solving problems automatically. Trial programs are frequently altered in the search for obtaining superior solutions due to the base is GA. These are evolutionary search techniques inspired by biological evolution such as mutation, reproduction, natural selection, recombination, and survival of the fittest. The power of GAs is being represented by an advancing range of applications; vector processing, quantum computing, VLSI circuit layout, and so on. But one of the most significant uses of GAs is the automatic generation of programs. Technically, the GP solves problems automatically without having to tell the computer specifically how to process it. To meet this requirement, the GP utilizes GAs to a "population" of trial programs, traditionally encoded in memory as tree-structures. Trial programs are estimated using a "fitness function" and the suited solutions picked for re-evaluation and modification such that this sequence is replicated until a "correct" program is generated. GP has represented its power by modifying a simple program for categorizing news stories, executing optical character recognition, medical signal filters, and for target identification, etc. This paper reviews existing literature regarding the GPs and their applications in different scientific fields and aims to provide an easy understanding of various types of GPs for beginners.

A Study on the Etching of SUS MASK using Automatic Liquid Management System (자동액관리 시스템을 이용한 SUS MASK 에칭에 관한 연구)

  • Lee, Woo-Sik
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
    • /
    • v.14 no.4
    • /
    • pp.323-327
    • /
    • 2021
  • This paper produced SUS MASK, which is used for OLEDs, using an automatic liquid management system. The SUS MASK was tested by setting the hole diameter to 0.4 mm. The additive F300 was found to be excellent as the hole diameter was close to 0.4 mm and the error range was measured to be 0.08 on average. And as a result of measuring the weight reduction amount of CuCl2 and FeCl3 according to the change in oxidation-reduction potential (ORP), FeCl3 is relatively sensitive to ORP changes. Experiments were conducted on whether ORP (610 mV) and specific gravity (1.463) were automatically controlled while continuously etching the SUS Mask. Experimental results show that the automatic liquid management system is well controlled because the setting value is not significantly changed. After setting the hole diameter to 0.4 mm as the target, the experiment results were measured from 0.36 to 0.44. Therefore, it is expected that etching processing in the manufacturing process of SUS MASK can be improved with higher precision by applying the manufactured automatic liquid management system.

A Study on the Management of the Indian Ocean Tuna Fishing Grounds (인도양 다랭이어업의 어장관리에 관한 연구)

  • Gong, Yeong;Park, Yeong-Chull;Yang, Won-Seok;Lee, Je-Hu
    • The Journal of Fisheries Business Administration
    • /
    • v.18 no.1
    • /
    • pp.59-97
    • /
    • 1987
  • Tuna and tuna fishing extend over most of the tropical waters of the world oceans, especially, this study of the Indian Ocean and the fish and the fishing vessels are highly mobile. No country can deal in isolation with the problems of its tuna fishery and of any tuna fishery in its waters, without collaborating with other countries. This cooperation is often best established through some formal international mechanism. The essential requirements are for information-on the resources, the fishery, the trade-and to identify where management actions are needed to consore the resources or to maintain the economic or social function of the fishery. These will also usually require some form of international mechanism. With the changes in the Law of the Sea, the siuuation in respect of management of tuna-considered among the highly migratory species, requirng special treatment-has also changed. At present there are both uncertainty regarding tuna management and political arguments as to how such management can be best implemented. Bearing this in mind, together with the fact that only few tuna stocks have shown clear evidence of serious depletion through over-exploitation, present emphasis will be placed on information requirements. This study included compiling the data necessary to review the state of stoks in the Indian Ocean tuna fishing grounds. Information on the resources-where the fish are, their quantity, their movements, etc. is important, whether in planning development of new fisheries, or considering the need for collaboration with other countries (in ascertaining to what extent their catches may affect catches of the natoinal fleet) or for conservation measures. A major source of information is the statistics of for conservation measures. A major source of information is the statistics of catch and fishing effort from existing commercial vessels. These need to be assembled for all fisheries on the same stock on an oceanwide basis. The statistical data also need to be analysed and intepreted, and combined with biological data(e.g., on growth, mortality and migration rates) to provide information that is intelligible and useful for administrators and other decision-makers. This must also be undertaken on a resource-wide or ocean-wide basis. Finally, because of the world-wide similarities in the methods of datching, processing and marketing fish, there is a particular tut not exclusive need in those countries just beginning to develop their tuna fisheries-to have ready access to a syntheis of information on tuna, tuna biology and tuna fisheries and tuna fisheries economics and management on the Indian Ocean.

  • PDF

Changes in Alcohol Dehydrogenase (ADH) and Acetaldehyde Dehydrogenase (ALDH) Activity during the Processing of Salt-Dried Rockfish Sebastes schlegeli (염건 조피볼락(Sebastes schlegeli) 제조 중 ADH 및 ALDH의 활성변화)

  • Shim, Kil Bo;Lee, Hyun Jin;Lee, So Jeong;Cho, Hyun Ah;Yoon, Na Young;Lim, Chi Won
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.45 no.6
    • /
    • pp.594-599
    • /
    • 2012
  • The objective of this study was to determine the processing conditions for salt dried rockfish Sebastes schlegeli by sun drying and cold-air drying, as measured by alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activity. We processed salt dried rockfish samples. The salinity of rockfish samples was within 1% following salting with 25% salt brine for 3 h. The moisture content of salt dried rockfish was found to reduce linearly from 70.12 to 39.5 g/100 g over the same time interval. The water activities of salt dried rockfish by sun and cold-air drying were 0.94 and 0.87, respectively, after three days of drying. Acid values (AV) were 10.71 and 5.96 mg KOH/g, respectively, after the three day drying period. The ADH activity in a water extract from salt dried rockfish following sun and cold-air drying for 24 h was 228.5% and 226.1% at 13.3 mg/mL, respectively, and was higher than that when drying lasted for 48 and 72 h. The ALDH activity was not affected but both ADH and ALDH activity tended to decrease as the drying time increased from 24 to 72 h. The conditions of processing for the best quality of salt dried rockfish were determined to be drying with a cold-air system for 24 h. These results indicated that water extracts from salt dried rockfish have valuable biological attributes owing to the metabolizing of alcohol and can provide useful information for the design of drying systems for salt dried rockfish.