• Journal of Photoscience
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• 제3권3호
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• pp.153-158
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• 1996

The effects of $\alpha$- and $\beta$-cyclodextrins (CD) on the twisted intramolecular charge transfer (TICT) behavior of p-N,N'-dimethylaminobenzoic acid (DMABA) in buffered aqueous solution have been investigated by examining formation and decay behaviors of the TICT-typical dual fluorescence. The ratio of the TICT emission to the normal emission (I$_a$/I$_b$) increases linearly $\alpha$-CD concentration increases, while in the presence of $\beta$-CD it shows nonlinear dependences on the CD concentration. The analysis of the CD-dependent changes of the I$_a$/I$_b$ and absorption spectra demonstrates formation of 1:1 inclusion complexes between DMABA and CDs. The decay time of the normal emission (ca. 700 ps) is little affected by the formation of $\alpha$-CD inclusion complex, whereas it increases upto ca. 1.6 ns upon formation of $\beta$-CD inclusion complex. The TICT emission for the $\beta$-CD inclusion complex exhibits two decay components while it shows a single component for the $\alpha$-CD inclusion complex, indicating formation of one or two types of inclusion complex in the presence of $\alpha$-CD or $\beta$-CD, respectively. These results are attributed to the CD cavity size dependence on patterns of complexation between CDs and DMABA. The CD size dependences of the TICT fluorescence properties with the orientation of the guest molecule demonstrate that the specific hydrogen bonding between the carboxylic acid group and water plays an important role in the excited-state TICT.

• 한국자동차공학회논문집
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• 제15권6호
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• pp.87-93
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• 2007

It is complicate to analysis the systems, dual mode hybrid systems, because they are composed of many planetary gear sets. For the performance test, it needs to define the systems with representative parameters. In this paper, system parameters, $\alpha$, $\beta$, $\zeta$, are introduced to define the systems, and an arbitrary system like E-IVT developed by Renault Motors is converted to the general system having equivalent parameters, such as $\beta'$, $R'_b$. Pontryagin principle and Kuhn-Tucker condition method are applied to solve the constrained problems, by which the methodology for accelerating test is generalized, and the results of the simulation are reported. In addition, the effects of alternative strategies are mentioned. The method of fuel economy test at engine mode is also introduced. The results of test at engine mode is different from the results of optimal trajectory, but the fuel economy of the engine mode is related to the highway driving and optimized operating of the system.

• 대한임상검사과학회지
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• 제50권4호
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• pp.492-500
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• 2018

본 연구는 이중과제 병합 가상현실 프로그램을 경도인지장애 노인에게 적용하여 인지기능, 균형과 뇌파에 미치는 영향을 알아보았다. 이중과제 병합 가상현실 프로그램을 중재한 실험군 집단과 전통적인 작업치료를 중재한 대조군 집단은 1회 30분, 1주일 5회, 총 6주에 걸쳐 실시하였다. 연구 결과는 첫째, 이중과제 병합 가상현실 프로그램을 시행한 실험군이 전통적인 작업치료를 시행한 대조군에 비해 인지기능 중 기억력 항목과 균형 항목에서 유의하게 증가하였다. 둘째, 이중과제 병합 가상현실 프로그램을 시행한 실험군이 전통적인 작업치료를 시행한 대조군에 비해 ${\beta}$파와 SMR파의 세기가 유의하게 증가하였다. 결과를 종합해보면, 이중과제 병합 가상현실 프로그램이 경도인지장애 노인에게 효과적인 치료방법이었고, 다양한 질환을 겪고 있는 대상자들에게 도움이 되는 기초 자료의 초석이 되기를 바란다.

• 한국산학기술학회논문지
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• 제19권7호
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• pp.453-462
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• 2018

본 연구는 부모의 나트륨 섭취량과 청소년 자녀의 나트륨 섭취량이 일치하는지에 대해 파악하고, 청소년 자녀의 나트륨 섭취량에 영향을 미치는 요인을 파악하고자 하며, 그 결과에 따라 가정에서의 나트륨 섭취량을 조절할 수 있는 방안을 제시하는 것에 목적이 있다. 2015년 국민건강영양조사 자료에서 연구대상자를 영양섭취량 중에서도 나트륨 섭취량이 측정된 만 7세에서 만 18세까지의 초등학생, 중학생, 고등학생을 추출하고, 결측값을 제외하여 최종분석대상자는 405명이었다. 그리고 청소년 ID에 아버지 ID와 어머니 ID로 데이터를 매칭하여 생성하였다. 연구결과 청소년은 여자 청소년보단 남자 청소년이 ${\beta}=-.187$, 청소년의 연령이 높을수록 ${\beta}=.192$, 외식빈도가 많을수록 ${\beta}=.153$, 나트륨 섭취량이 높아졌다. 그리고 아버지보다는 어머니의 연령이 높을수록 ${\beta}=.171$, 나트륨 섭취량이 높을수록 ${\beta}=.136$으로 청소년의 나트륨 섭취량이 높았다. 이 점은 우리나라는 어머니가 주로 식사준비를 하는 경우가 많기 때문이다. 그러나 한편으로는 맞벌이 부부의 증가로 부모가 자녀의 질적인 식사를 고려하지 못하게 되어 자녀의 식사를 외식에 의존하는 경우도 적지 않을 것으로 예측되어 그러한 관점에서의 실태조사가 추후 필요하다.

• 한국식품영양학회지
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• 제29권6호
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• pp.1050-1057
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• 2016

SNS (Social network service) characteristics are perceived to simplify use. We carried out empirical studies on these parameters to observe the impact on the image of catering SNS online by word-of-mouth. The subjects of the study were as follows: 32.3% (392 persons) 19 years old, 67.7% (821 persons) over 19 years, 51.0% (619 persons) in their 20s, 22.1% (268 persons) in their 30s, 17.6% in their 50s, and 9.3% (112 persons) over 50 years. After verifying the hypothesis proposed that SNS characteristics perceived the ease of use, the significant factor identified in usability were connectivity Speed (${\beta}=0.213$), playfulness (${\beta}=0.246$), information (${\beta}=0.115$), and reciprocity (${\beta}=0.357$). Dual reciprocity had the most impact. It was observed that a longer impact of these significant factors improved the feel and fun of use. If SNS companies cater to, quick and easy, diverse, reliable and latest information, they can increase the ease of use, and availability, depending on the goals. Also, significant factors in the SNS features and online word of mouth was playfulness (${\beta}=0.312$), information (${\beta}=0.207$), reciprocity (${\beta}=0.066$) and perceived ease of use, and usefulness (${\beta}=0.293$), double playfulness had the maximum impact. These features provided more fun, reliable information, and could quickly deliver the latest information. The more the perceived usefulness, and ease of use, higher was the online word-of-mouth effect. SNS usage characteristics of connectivity Speed did not show any statistical significance in online word-of-mouth. Thus, catering businesses need to find ways to increase the ease of use, make the usefulness multifaceted, constantly checking the catering information on the SNS and ensuring to get the latest information is from diverse and reliable sources. This would increase the fun for the customer making the SNS to actively be utilized as a marketing tool.

• 약학회지
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• 제49권2호
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• pp.147-150
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• 2005

Macrophage scavenger receptors (MSRs) induce microglial interaction with ${\beta}$-amyloid fibrils (fA${\beta}$) that are associated with Alzheimer's disease (AD). Although microglia are know n to have a dual effect on formation of plaque and clearance of fA${\beta}$ in the AD brain, receptor-mediated phagocytosis is a very important tool for preventing amyloid plaque via activated microglia in the early stage of AD. In the study, we examined whether ginsonoside Rg3 enhances the microglial Phagocytosis of A${\beta}$1-42 through Phagocytosis assay, gene expression (RT-PCR) and protein assay (western blots) for the cell responsiveness presented between Rg3-treated and non-treated groups. Fluro-labeled Ac-LDL and E.coli particles were used as control proteins for phagocytosis. In previous studies, this was a particularly interesting property of Rg3 in the stimulation and phagocytosis of macrophages in the periphery. We report here that ginsenoside Rg3 increased the expression of type-A MSR (MSR-A) in microglia and thus accelerated the phagocytosis with an effective degradation of engulfed fA${\beta}$. This result suggests that Rg3 may play an important role in removing fA${\beta}$ by enhancing the receptor-mediated phagocytosis. In addition, Rg3 could be a potential candidate for balancing the rate of production of fA${\beta}$ in AD brain.

• The Journal of Korean Physical Therapy
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• 제33권3호
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• pp.136-141
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• 2021

Purpose: Dementia is a disease in which cognitive function declines, leading to deterioration of body functions and activities of daily living. The purpose of this study is to explore the effects of dual-task training, including cognitive tasks, on cognitive and body function and β-amyloid levels in Alzheimer's dementia patients. Methods: 34 inpatients diagnosed with Alzheimer's dementia at a nursing hospital located in South Korea. The patients were randomly divided into a dual-task group (n=16) and a single-task group (n=18). Each group was trained for 30 minutes three times a week for eight weeks. The MMSE-K was used to measure the patients' cognitive function. To assess the patients' static balance ability, their LOS was measured using BioRescue. while dynamic balance was measured using the BBS. The 10MWT were conducted to evaluate the patients' walking ability. Blood analysis was performed to measure levels of β-amyloid. Results: Both groups exhibited statistically significant improvements in gait function after the training (p<0.05). The dual-task group exhibited statistically significant differences in cognitive function, static and dynamic balance function, and β-amyloid levels after training (p<0.05). A significant difference was observed between the two groups (p<0.05). Conclusion: Dual-task training were found to be effective in improving cognitive and bodily functioning and reducing β-amyloid levels in Alzheimer's dementia patients. Thus, this may be suggested as an effective exercise method for the treatment and early prevention of Alzheimer's dementia.

• Bulletin of the Korean Chemical Society
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• 제23권9호
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• pp.1241-1255
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• 2002

Series of m- and p-substituted benzyl derivatives of pyrrole, tetramethyl 1-benzyl-3a,7a-dihydroindole-2,3,3a,4-tetracarboxylate, and trimethyl 1-benzylindole-2,3,4-tricarboxylate were prepared and their 13C NMR spectra were obtained in 0.1 M solutions of chloroform-d. Both single substituent parameter and dual substituent parameter analyses were carried out to correlate the substituent chemical shifts. The ${\beta}$ carbon of the indole series showed the most profound substituent effect dependence as well as the best correlation. The results are explained by the hyperconjugation of the benzyl methylene group.

• 대한수학회논문집
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• 제34권2호
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• pp.401-414
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• 2019

Let ${\mathcal{F}}$ denote an algebraically closed field with characteristic not two. Fix an integer $d{\geq}3$, let $Mat_{d+1}({\mathcal{F}})$ denote the ${\mathcal{F}}$-algebra of $(d+1){\times}(d+1)$ matrices with entries in ${\mathcal{F}}$. An ordered pair of matrices A, $A^*$ in $Mat_{d+1}({\mathcal{F}})$ is said to be LB-TD form whenever A is lower bidiagonal with subdiagonal entries all 1 and $A^*$ is irreducible tridiagonal. Let A, $A^*$ be a Leonard pair in $Mat_{d+1}({\mathcal{F}})$ with fundamental parameter ${\beta}=2$, with this assumption there are four families of Leonard pairs, Racah, Hahn, dual Hahn, Krawtchouk type. In this paper we show from these four families only Racah and Krawtchouk have LB-TD form.

• 한국수정란이식학회:학술대회논문집
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• 한국수정란이식학회 2002년도 국제심포지엄
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• pp.71-71
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• 2002

Promoters for milk proteins have been used far producing transgenic animals due to their temporal and spatial expression patterns. ${\beta}$-casein, a calcium-sensitive casein, is a major milk protein that corresponds ca. 30 per cent of total milk protein. Expression of ${\beta}$-casein is controlled by lactogenic hormones such as prolactin (PRL), composite response elements (CoREs) and transcription factors. CoREs are clusters of transcription factor binding sites containing both positive and negative regulatory elements. ${\beta}$-casein gene promoter contains various regions (CoREs) for gene transcription. We analyzed the promoter region by mutagenesis using exonuclease III and linker-scanning. Transcription control elements usually are positioned in 5'-flanking region of the gene. However, in some cases, these elements are located in other regions such as intron 1. The nucleotide sequences of ${\beta}$-casein promote. region has been reported (E12614). However, the properties of the promoter is not yet clear. In this study, we plan to investigate the properties of cis-regulating elements of porcine ${\beta}$-casein by mutation analysis and expression analysis using dual-luciferase repoter assay system.