• Title/Summary/Keyword: beta type

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The effects of dental medical institutions of user reactions by mobile message type (모바일메시지 속성별 이용자 반응이 치과의료 이용의사에 미치는 영향)

  • Im, Ae-Jung;Han, Soo-Yeoun;Lim, Hee-Jung
    • The Journal of Korean Society for School & Community Health Education
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    • v.20 no.2
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    • pp.81-91
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    • 2019
  • Objectives: It helps dental clinic to work 1:1 consulting and select the properties of the Kakao Talk message. The study was designed to determine the influence of users cognitive and emotional responses by message attribute that affect intention of use of dental clinic. Methods: This study targeted 297 peple Kakao Talk users aged 20-50 s, in Seoul, Gyeonggi-do and Incheon from, February 6 to April 7, 2017. We analyzed the data with frequency analysis, t-test, one-way ANOVA, and multiple regression analysis by using SPSS ver 24.0(SPSS Inc, Chicago, USA). The significance level for significance was set at 0.05. Results: Among the user's responses about the event type Kakao talk message, the ease(${\beta}=0.121$, p<0.01), usefulness(${\beta}=0.148$, p<0.001), affinity(${\beta}=0.471$, p<0.001), satisfaction(${\beta}=0.249$, p<0.001). affected intention of use of dental clinic. Among the user's responses about the dental information type, the ease(${\beta}=0.150$, p<0.05), expertise(${\beta}=0.151$, p<0.05), satisfaction(${\beta}=0.237$, p<0.001) affected intention of use of dental clinic(p<0.05). Among the user's responses about the general public relations type, the expertise(${\beta}=0.254$), affinity(${\beta}=0.193$), satisfaction(${\beta}=0.474$) affected intention of use of dental clinic(p<0.001). Conclusion: It is necessary to elicit a positive intention of use of dental clinic through a highly emotional response from the users to improve the image of the dental clinic and to attract patients.

Mutational Analysis of Thermus caldophilus GK24 ${\beta}$-Glycosidase: Role of His119 in Substrate Binding and Enzyme Activity

  • Oh, Eun-Joo;Lee, Yoon-Jin;Choi, Jeong-Jin;Seo, Moo-Seok;Lee, Mi-Sun;Kim, Gun-A;Kwon, Suk-Tae
    • Journal of Microbiology and Biotechnology
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    • v.18 no.2
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    • pp.287-294
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    • 2008
  • Three amino acid residues (His119, Glu164, and Glu338) in the active site of Thermus caldophilus GK24 ${\beta}$-glycosidase (Tca ${\beta}$-glycosidase), a family 1 glycosyl hydrolase, were mutated by site-directed mutagenesis. To verify the key catalytic residues, Glu164 and Glu338 were changed to Gly and Gln, respectively. The E164G mutation resulted in drastic reductions of both ${\beta}$-galactosidase and ${\beta}$-glucosidase activities, and the E338Q mutation caused complete loss of activity, confirming that the two residues are essential for the reaction process of glycosidic linkage hydrolysis. To investigate the role of His119 in substrate binding and enzyme activity, the residue was substituted with Gly. The H119G mutant showed 53-fold reduced activity on 5mM p-nitrophenyl ${\beta}$-D-galactopyranoside, when compared with the wild type; however, both the wild-type and mutant enzymes showed similar activity on 5mM p-nitrophenyl ${\beta}$-D-glucopyranoside at $75^{\circ}C$. Kinetic analysis with p-nitrophenyl ${\beta}$-D-galactopyranoside revealed that the $k_{cat}$ value of the H119G mutant was 76.3-fold lower than that of the wild type, but the $K_m$ of the mutant was 15.3-fold higher than that of the wild type owing to the much lower affinity of the mutant. Thus, the catalytic efficiency $(k_{cat}/K_m)$ of the mutant decreased to 0.08% to that of the wild type. The $k_{cat}$ value of the H119G mutant for p-nitrophenyl ${\beta}$-D-glucopyranoside was 5.l-fold higher than that of the wild type, but the catalytic efficiency of the mutant was 2.5% of that of the wild type. The H119G mutation gave rise to changes in optima pH (from 5.5-6.5 to 5.5) and temperature (from $90^{\circ}C\;to\;80-85^{\circ}C$). This difference of temperature optima originated in the decrease of H119G's thermostability. These results indicate that His119 is a crucial residue in ${\beta}$-galactosidase and ${\beta}$-glucosidase activities and also influences the enzyme's substrate binding affinity and thermostability.

Analysis of Volatile Oil Components and Identification of Chemotypes in Jaso (Perilla frutescens) Collected in Korea

  • Ohk, Hyun-Chung;Chae, Young-Am
    • Korean Journal of Medicinal Crop Science
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    • v.12 no.2
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    • pp.97-101
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    • 2004
  • Volatile oil components were analysed in Perilla frutescens accessions collected from different regions in South Korea and identified chemotypes based on the major volatile oil components. Major components out of 30 compounds identified were limonene, perillaldehyde, perillaketone, isoegomaketone, beta-caryophyllene, beta-farnesene, myristicin, and dillapiole. P. frotescens collections were classified into four chemotypes : PA type (57.7% limonene and 19.8% perillaldehyde), PK type (89.8% perillaketone), ST type (82.4% sesquiterpene, as 54.5% beta-caryophyllene and 27.9% beta-farnesene) and PP type (40.3% phenylpropenes as 13.6% myristicin and 26.7% dillapiole) and 37.8% sesquiterpenes. The majorities of P. frutescens collections in this study belong to PA type (41.9%) and PK type(38.8%).

Inhibition of Endothelial Cell-dependent Serotonin-induced Contraction of ${\beta}-endorphin$ and Increment of Plasma ${\beta}-endorphin$ of Silver Spike Point Low Frequency Electrical Stimulation (${\beta}-Endorphin$의 내피세포의존성-세로토닌 유도-근 수축 억제와 저빈도-주파수 은침점전자극의 혈장 ${\beta}-endorphin$ 증가)

  • Choi Young-Duk;Lee Joon-Hee;Kim Jung-Hwan
    • The Journal of Korean Physical Therapy
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    • v.16 no.3
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    • pp.22-31
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    • 2004
  • The purpose of this study was to demonstrate the effects of silver spike point (SSP) low frequency electrical stimulation on plasma ${\beta}-endorphin$ activities measured by radio- immunoassay from normal volunteer and the effects of ${\beta}-endorphin$ on 5-hydroxytryptamine (5-HT, serotonin)-induced contraction investigated by isometric tension methode in rats. The current of 3 Hz continue type, but not 100 Hz continue type, of SSP low frequency electrical stimulation significantly increased in plasma ${\beta}-endorphin$ from normal volunteer. The endothelial cell-dependent 5-HT-induced contractions were inhibited by ${\beta}-endorphin$ $1{\mu}M$. These results suggest that the ${\beta}-endorphin$ regulates nociceptive-like substance, such as 5-HT, in part and that the SSP low frequency electrical stimulation, specifically current of low frequency of 3 Hz continue type, significantly increases plasma ${\beta}-endorphin$ from normal volunteer.

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$\beta$-Lactamase Inhibitory Activity and Comparative Activity of Sulbactam Derivatives Combined with $\beta$-Lactam Antibiotics (Sulbactam 유도체의 베타락타마제 효소억제력과 베타락탐항생제 병용시 활성비교)

  • 임채욱;박희석;김용현;임철부
    • YAKHAK HOEJI
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    • v.46 no.6
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    • pp.387-391
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    • 2002
  • In vitro $\beta$-lactamase inhibitory activity of 6-exomethylene sulbactam compounds (CH-120, 130, 140, 145, 150, 155) was compared with clavulanic acid, sulbactam and tazobactam. The inhibitory activity of CH-140 was stronger than sulbactam and clavulanic acid against Type II, III, IV, TEM enzymes and stronger than tazobactam against Type IV enzyme. The inhibitory activity of CH-145 was stronger than sulbactam and clavulanic acid against Type I, II, III, IV, TEM enzymes and stronger than tazobactam against Type III, IV enzymes. The in vitro antimicrobial activity of CH-140 and CH-145 combined with piperacillin and ceftriaxone was compared with the sulbactam and tazobactam against $\beta$-lactamase producing 31 strains. But, synergistic activity of CH-140 and CH-145 was inferior to tazobactam.

$\beta$-Lactamase Inhibitory Activity and Comparative Activity of 6-Exomethylenepenam Derivatives Combined with $\beta$-Lactam Antibiotics (6-Exomethylenepenam유도체의 베타락타마제 효소억제력과 베타락탐항생제 병용시 활성비교)

  • 임채욱;박희석;정미량;강주성;임철부
    • YAKHAK HOEJI
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    • v.47 no.6
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    • pp.456-460
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    • 2003
  • In vitro $\beta$-lactamase inhibitory activity of 6-exomethylenepenam compounds ( 1, 2, 3, 4 and 5) was compared with clavulanic acid, sulbactam and tazobactam. The inhibitory activity of compound 3 was stronger than those of sulbactam and clavulanic acid against Type I and II enzymes and stronger than tazobactam against Type III, IV, TEM enzymes. The inhibitory activity of 5 was stronger than sulbactam and clavulanic acid against Type I and II enzymes and stronger than tazobactam against Type III, and IV enzymes. The in vitro antimicrobial activity of 3, 4 and 5 combined with ampicillin and cefoperazone was compared with the sulbactam against $\beta$-lactamase producing 27 strains. But, synergistic activity of 3 and 5 was inferior to tazobactam.

Some Common Fixed Points for Type(β) Compatible Maps in an Intuitionistic Fuzzy Metric Space

  • Park, Jong Seo
    • International Journal of Fuzzy Logic and Intelligent Systems
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    • v.13 no.2
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    • pp.147-153
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    • 2013
  • Previously, Park et al. (2005) defined an intuitionistic fuzzy metric space and studied several fixed-point theories in this space. This paper provides definitions and describe the properties of type(${\beta}$) compatible mappings, and prove some common fixed points for four self-mappings that are compatible with type(${\beta}$) in an intuitionistic fuzzy metric space. This paper also presents an example of a common fixed point that satisfies the conditions of Theorem 4.1 in an intuitionistic fuzzy metric space.

GENERALIZED (α, β, γ) ORDER AND GENERALIZED (α, β, γ) TYPE ORIENTED SOME GROWTH PROPERTIES OF COMPOSITE ENTIRE AND MEROMORPHIC FUNCTIONS

  • Tanmay Biswas;Chinmay Biswas
    • The Pure and Applied Mathematics
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    • v.31 no.2
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    • pp.119-130
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    • 2024
  • In this paper we discuss on the growth properties of composite entire and meromorphic functions on the basis of generalized (α, β, γ) order and generalized (α, β, γ) type comparing to their corresponding left and right factors.

Effects of Doula-type-delivery Nursing Care on Plasma $\beta$-Endorphin, Serum Cortisol related to Delivery Stress during Labor, and Postpartum Status Anxiety of Primipara - Clinical trial - (Doula식 분만간호가 초산부의 분만중 분만스트레스로 인한 혈장 베타엔돌핀, 혈청 코티졸 및 분만후 상태불안에 미치는 효과 - 임상 실험연구 -)

  • Hur, Myung-Haeng
    • Women's Health Nursing
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    • v.7 no.1
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    • pp.67-79
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    • 2001
  • This study was designed to verify the effect of Doula-type-delivery nursing care on plasma $\beta$-endorphin, serum cortisol, related to delivery stress during labor, and postpartum anxiety of primipara by a quasi experiment(nonequivalent control group pretest-posttest design), from December, 1999 to August, 2000. The subjects of this experiment consisted of sixty eight primipara, with single gestation, full term, uncomplicated pregnancies, thirty three for the experimental group and thirty five for the control group. Their mean age was 26.1 years for the experimental group and 25.5 years for the control group. Their mean gestation period was 39.7 weeks for the experimental group and 40.1 weeks for the control group. As treatment, Doula-type-delivery nursing care was given for the experimental group. Data assessed plasma $\beta$-endorphin, serum cortisol during labor, and anxiety during postpartum. Plasma $\beta$-endorphin, serum cortisol were measured in the latent phase before treatment(pre-test) and the transition phase after treatment(posttest). Also, anxiety was measured in the latent phase before treatment(pre-test) and 24 hours postpartum after treatment(posttest). Data was analyzed by t-test, $x^2$-test, Repeated measures ANOVA with SAS Program. The results of this study were as follows; 1. Plasma $\beta$-endorphin was significantly elevated in the experimental group who were cared for with Doula-type-delivery nursing care during labor(P=.0463). 2. No significant group effects were found, but significant time effects were found for serum cortisol. 3. The postpartum anxiety of the experimental group was significantly lower than the control group(P=.0110). In conclusion, these findings indicate that Doula-type-delivery nursing care during labor could be effective in increasing maternal plasma $\beta$-endorphin and decreasing postpartum anxiety. Doula-type-delivery nursing care during labor could be applied as an effective nursing treatment for primipara.

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STATISTICAL CONVERGENCE FOR GENERAL BETA OPERATORS

  • Deo, Naokant;Ozarslan, Mehmet Ali;Bhardwaj, Neha
    • Korean Journal of Mathematics
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    • v.22 no.4
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    • pp.671-681
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    • 2014
  • In this paper, we consider general Beta operators, which is a general sequence of integral type operators including Beta function. We study the King type Beta operators which preserves the third test function $x^2$. We obtain some approximation properties, which include rate of convergence and statistical convergence. Finally, we show how to reach best estimation by these operators.