• Title/Summary/Keyword: association mapping

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Current Status of Comparative Mapping in Livestock

  • Lee, J.H.;Moran, C.;Park, C.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.16 no.10
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    • pp.1411-1420
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    • 2003
  • Comparative maps, representing chromosomal locations of homologous genes in different species, are useful sources of information for identifying candidate disease genes and genes determining complex traits. They facilitate gene mapping and linkage prediction in other species, and provide information on genome organization and evolution. Here, the current gene mapping and comparative mapping status of the major livestock species are presented. Two techniques were widely used in comparative mapping: FISH (Fluorescence In Situ Hybridization) and PCR-based mapping using somatic cell hybrid (SCH) or radiation hybrid (RH) panels. New techniques, using, for example, ESTs (Expressed Sequence Tags) or CASTS (Comparatively Anchored Sequence Tagged Sites), also have been developed as useful tools for analyzing comparative genome organization in livestock species, further enabling accurate transfer of valuable information from one species to another.

Methodology of Mapping Quantitative Trait Loci for Binary Traits in a Half-sib Design Using Maximum Likelihood

  • Yin, Zongjun;Zhang, Qin;Zhang, Jigang;Ding, Xiangdong;Wang, Chunkao
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.12
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    • pp.1669-1674
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    • 2005
  • Maximum likelihood methodology was applied to analyze the efficiency and statistical power of interval mapping by using a threshold model. The factors that affect QTL detection efficiency (e.g. QTL effect, heritability and incidence of categories) were simulated in our study. Daughter design with multiple families was applied, and the size of segregating population is 500. The results showed that the threshold model has a great advantage in parameters estimation and power of QTL mapping, and has nice efficiency and accuracy for discrete traits. In addition, the accuracy and power of QTL mapping depended on the effect of putative quantitative trait loci, the value of heritability and incidence directly. With the increase of QTL effect, heritability and incidence of categories, the accuracy and power of QTL mapping improved correspondingly.

Mapping of the Porcine Calpastatin Gene and Association Study of Its Variance with Economic Traits in Pigs

  • Choi, B.H.;Lee, J.S.;Jang, G.W.;Lee, H.Y.;Lee, J.W.;Lee, K.T.;Chung, H.Y.;Park, H.S.;Oh, S.J.;Sun, S.S.;Myung, K.H.;Cheong, I.C.;Kim, T.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.8
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    • pp.1085-1089
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    • 2006
  • The objectives of this study were to confirm a location of the calpastatin (CAST) gene in chromosome 2 and to detect associations of genetic variations with economic traits in the porcine CAST gene as a candidate gene for growth and meat quality traits in pigs. Calpastatin is a specific endogenous inhibitor of calpains. The calpain protease system is ubiquitous, and is involved in numerous growth and metabolic processes. Three single nucleotide variations were identified within a 1.6 kb fragment of the porcine CAST gene and these polymorphisms were used for genetic linkage mapping. Linkage and QTL mapping were performed with the National Livestock Research Institute (NLRI) reference families using eight microsatellites and SNP makers in the CAST gene. The porcine CAST gene was mapped adjacent to the markers, SW395 and SW1695 on SSC2 with LOD scores of 15.32 and 8.50, respectively. According to the QTL mapping, a significant association was detected at 82 cM between SW395 and CAST-Hinf I for weight at the age of 30 weeks. In addition, an association study was performed with the $F_2$ animals of NLRI reference families for Hinf I, Msp I and Rsa I polymorphisms in the CAST gene. Two polymorphisms, CAST-Rsa I and CAST-Hinf I, showed significant correlation for growth traits at p<0.01 and p<0.05, respectively.

A Study on the Types of Camera Working of Projection Mapping Contents (프로젝션 매핑 콘텐츠의 카메라 움직임 유형에 관한 연구)

  • Song, Min Ji;Park, Jin Wan
    • The Journal of the Korea Contents Association
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    • v.14 no.8
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    • pp.1-12
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    • 2014
  • The projection mapping technique is used in various ways in almost every genre of performance arts at the moment. Thus, artist from various areas are participated in contents productions using it. The diversification of projection mapping contents gave producers a clue to try fresher visual effects and it was connected to the change of point of time using the camera working which was never used in old projection mapping contents productions. It is analyzed that the use of camera workings in the projection mapping image maximizes the visual Tactility and helps audiences concentrate on the contents. This study performed the theoretical research on the 'camera working' which is a new visual expression of the projection mapping and analyzed cases of projection mapping works applying them. It is to reconstruct the camera working which has been applied only by images of movies and suggest a guideline to create the optimized visual effect.

The Effects of Analyzing Mapping Errors in Concept Learning on the Three States of Matter with Analogy (비유를 사용한 물질의 세 가지 생태 개념 학습에서 대응 오류 분석 활동의 효과)

  • Kim, Kyung-Sun;Byun, Ji-Sun;Shin, Eun-Ju;Noh, Tae-Hee
    • Journal of The Korean Association For Science Education
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    • v.27 no.9
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    • pp.778-786
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    • 2007
  • This study investigated the effects of analyzing mapping errors on conceptual understanding, mapping understanding and perceptions of the instructions in learning chemistry concept with analogy. Seventh graders (N=121) at two middle schools were assigned to the comparison and the treatment groups, and were taught about 'states of matter and arrangement of molecules.' The students in the comparison group were taught in the Teaching-With-Analogy (TWA) model, while those in the treatment group Were taught in the instructional model that changed 'mapping similarity' and 'indicating difference' of the TWA model into 'analyzing mapping errors.' Analysis of the results revealed that the scores of the conception test and the mapping test for the treatment group were significantly higher than those far the comparison group regardless of field dependence-independence. It was also found that most students in the two groups positively perceived the instructions with analogy, but the students in the treatment group had difficulties in analyzing mapping errors, Educational implications are discussed.

Interactive Projection Mapping as a mean maintaining brand identity of corporation - Based on KIA Tigers (기업 브랜드 아이덴티티 유지 도구로서 Interactive Projection Mapping - 기아 타이거즈를 중심으로)

  • Shin, Chang-Woo;Han, Ji-Ae;Kim, Byung-Wook
    • Proceedings of the Korea Contents Association Conference
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    • 2014.11a
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    • pp.85-86
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    • 2014
  • 본 연구의 목적은 브랜드 홍보 잠재력이 낮아지고 있는 기업 브랜드의 아이덴터티 유지를 위한 도구로서 Projection Mapping의 활용 방안을 고찰하는 것이다. 브랜드 홍보 잠재력이 낮아지고 있는 지역 대표 기업인 기아 타이거즈를 연구 대상으로 선정하고, Brand Identity측면에서 Durability, Differentiation, Coherence, Flexibility 특성 중심으로 Interactive Projection Mapping을 구현하였다. 제작과정은 크게 C4d 를 활용한 홍보 영상 제작, VVVV와 Touch Sensor을 활용한 행동에 반응하는 영상 제어 과정으로 이루어졌다.

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A comparative analysis on concept mapping tools for computer-supported collaborative learning (컴퓨터기반 협력학습을 위한 개념도작성도구의 비교 분석 및 고찰)

  • Lee, Hyojin;Jeong, Seunghee;Yang, Sunyoung;Eun, Jihye;Kim, Kyungjin;Kim, Dongsik
    • The Journal of Korean Association of Computer Education
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    • v.18 no.3
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    • pp.37-47
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    • 2015
  • The purpose of this study is to review the concept mapping tools and provide implications for designing tools that support collaborative learning activities. For this purpose, representative concept mapping tools - Convince Me, Knowledge Forum, Cmaptools, Mindmeister, Belvedere - was analyzed by using the 3C(Communication, Coordination, Cooperation) framework. We have applied three research methods; 1) literature review on design principles of tools, 2) heuristic evaluation, 3) focus group interview. As a result, most of comcept mapping tools supported communication functions but partialy supported coordication and cooperation features.

Grid Map Building and Sample-based Data Association for Mobile Robot Equipped with Low-Cost IR Sensors (저가 적외선센서를 장착한 이동로봇에 적용 가능한 격자지도 작성 및 샘플기반 정보교합)

  • Kwon, Tae-Bum;Song, Jae-Bok
    • The Journal of Korea Robotics Society
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    • v.4 no.3
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    • pp.169-176
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    • 2009
  • Low-cost sensors have been widely used for mobile robot navigation in recent years. However, navigation performance based on low-cost sensors is not good enough to be practically used. Among many navigation techniques, building of an accurate map is a fundamental task for service robots, and mapping with low-cost IR sensors was investigated in this research. The robot's orientation uncertainty was considered for mapping by modifying the Bayesian update formula. Then, the data association scheme was investigated to improve the quality of a built map when the robot's pose uncertainty was large. Six low-cost IR sensors mounted on the robot could not give rich data enough to align the range data by the scan matching method, so a new sample-based method was proposed for data association. The real experiments indicated that the mapping method proposed in this research was able to generate a useful map for navigation.

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