• Title/Summary/Keyword: antimicrobial properties

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Development of Polymeric Drugs Utilizing Dithiocarbamate Chitosan: Formation and Antimicrobial Activities of Dithiocarbamate Chitosan-Ca(II)-Tetracycline Complex (Dithiocarbamate Chitosan을 Matrix로 이용한 고분자 약물의 개발 : Dithiocarbamate Chitosan-Ca(II)-Tetracycline Complex 의 생성 및 항균성)

  • 김윤택;김영미;한석규;정연진;유종호
    • YAKHAK HOEJI
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    • v.39 no.1
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    • pp.48-54
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    • 1995
  • Coupling of tetracycline(Tc) to dithiocarbamate chitosan(DTCC) via chelate bond was investigated varying reaction time, concentration, temperature, pH, and Ca(II)/Tc ratio. The amount of Tc bound to matrix increased to give a maximum and decreased as the reaction proceeded. The degree and rate of dissociation of Tc complex were affected by the reaction temperature, and pH. By running the reaction at low temperature and pH, the degree of dissociation was greatly diminished. Properties of drug-release from DTCC-Ca(II)-Tc complex were studied by batch- and flow-method and release of Tc and CA(II) by flow method followed nearly zero-order. DTCC-Ca(II)-Tc showed very prolonged antimicrobial activity compared to that of free Tc.

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Antimicrobial Effect of Carbon Dioxide on Microorganisms (이산화탄소의 항균 효과)

  • 홍석인;변유량
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.26 no.6
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    • pp.1258-1267
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    • 1997
  • Corbon dioxide id effective for extending the shelf-life of perishable foods by retarding microbial growth. The overall effect of carbon dioxide is to increase both the lag phase and generation time of microorganisms. However, the role of carbon dioxide in affecting the growth and metabolism of any given microorganisms is not clear yet, although its inhibitory effect is generally found at moderate to high concentrations. Systematic studies of the effects of carbon dioxide on microorganisms are therefore warranted. It is also necessary to understand the role of carbon dioxide in the preservation of foods as well as the control by carbon dioxide of fermentations of biotechnological importance. In this review, the antimicrobial effect of carbon dioxide on microorganisms is investigated in terms of its gas and solution properties, inhibition of microbial growth and specific metabolic processes, perturbation of membrane structure.

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A study on the prevalence of Riemerella anatipestifer from domestic ducks in Cheonan-Asan city (충남 천안아산지역에서 사육중인 육용오리의 리메렐라 감염율 조사)

  • Kim, Sue-Jung;Kang, Su-Jung;Yook, Sim-Yong
    • Korean Journal of Veterinary Service
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    • v.31 no.3
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    • pp.339-345
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    • 2008
  • This survey was carried out to investigate the infection rate of Riemerella anatipestifer from domestic ducks by isolation. A total of 145 samples (nasal swabs and carcasses) were collected from farms to examine the biochemical properties and antimicrobial susceptibility test from November 2006 to February 2008. Riemerella anatipestifer was isolated from 13 of 145 sample and isolation rate was higher in the ducks below 25 days (76%, 10/13 isolates) than those over 26 days (23%, 3/13). However, there was no significant difference in isolation rate between region. The biochemical properties of isolate were Gram negative (-), non-fermentative rod that grows fastidiously on routine media. In the test of antimicrobial drug susceptibility the isolates were susceptible to tetracycline(100%), enrofloxacin (77%), ampicillin (70%).

A Study on Comfort and Antimicrobial Properties of Sports Socks (Part II) -focused on antimicrobial, and shape-retention properties during wear and care- (스포츠 양말의 쾌적성과 항균성에 관한 연구 (제2보) -착용과 관리시에 항균성 밑 형태안정성을 중심으로-)

  • 박명자;김칠순;남영미;임정호
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
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    • 1998.11a
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    • pp.256-260
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    • 1998
  • 1스포츠 양말의 쾌적성과 항균성에 영향을 주는 인자 중에서 특히 양말의 항균성은 위생적인 쾌적감에 중요한 요소이고, 반복되는 착용과 관리도중 에 발생하는 양말의 형태변화는 착용자의 Fit감에 영향을 준다. 본 연구에서는 20종류의 양말시료를 섬유종류, 실의 굵기, 편성조직, 가공처리를 실험조건에 맞게 고려하여 직접 편성하거나 구입하여 사용하였다. 항균가공된 시판 양말의 항균성과 내세탁성, 양말의 착용과 관리 중에 문제가 되는 형태안정성에 관한 실험결과로서 얻은 결론은 다음과 같다. 1. 시판되는 항균가공양말의 항균성과 내세탁성은 모든 시료에서 매우 우수하게 나타나, 위생적인 의생활을 원하는 소비자들의 쾌적감을 충족시킬 수 있다. 2. 양말의 착용 중 또는 관리 중에 형태안정성을 결과를 보면, 섬유의 종류 편성조직에 영향을 받는데, 특히 면양말의 제작 시에는 착용 중에 발생하는 폭방향의 이완현상과 관리 중에 발생하는 길이수축현상을 고려하여 부위별 크기를 조절해야, Fit 감을 유지하며 이수축에 의한 문제발생을 줄일 수 있다.

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Potential Prebiotic Properties of Whey Protein and Glycomacropeptide in Gut Microbiome

  • Bryna Rackerby;Hoang Ngoc M. Le;Avery Haymowicz;David C. Dallas;Si Hong Park
    • Food Science of Animal Resources
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    • v.44 no.2
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    • pp.299-308
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    • 2024
  • Proteins in whey have prebiotic and antimicrobial properties. Whey protein comprises numerous bioactive proteins and peptides, including glycomacropeptide (GMP), a hydrophilic casein peptide that separates with the whey fraction during cheese making. GMP has traditionally been used as a protein source for individuals with phenylketonuria and also has prebiotic (supporting the growth of Bifidobacterium and lactic acid bacteria) and antimicrobial activities. GMP supplementation may help positively modulate the gut microbiome, help treat dysbiosis-related gastrointestinal disorders and improve overall health in consumers.

Dyeing Property and Antimicrobial activity of Protein Fiber Using Terminalia chebula Retzius Extract (가자열매 추출물을 이용한 단백질 섬유의 염색과 항균효과)

  • Nam, Ki Yeon;Lee, Jung Soon
    • Fashion & Textile Research Journal
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    • v.16 no.3
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    • pp.476-484
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    • 2014
  • The purpose of this study was to investigate the dyeing properties and anti-microbial ability of silk and wool fabrics dyed with Terminalia chebula Retzius(TCR) extract using two extraction solvent, hot water and methanol. Dyeing properties of fabrics were studied by investigating the characteristics of colorant, changes in dye uptake under different dyeing conditions, and by investigating color change when mordants were applied. Also, color fastness, and antimicrobial activity of dyed fabrics were estimated. Regardless of extraction solvent type, colorant showed maximum absorption wavelength at 280 nm and 578 nm, which implied that tannin was the major pigment component of TCR. Also, through FT-IR spectrum result, it was confirmed that tannin of TCR methanol extract was hydrolysable tannin. But for the hot water extract, it was only assumed that its tannin was condenced tannin. Fabric dyed with hot water solvent extract showed higher dye uptake than fabric dyed with methanol solvent extract, dye uptake increasing by higher concentration of the dye, longer dyeing time and higher dyeing temperature. And the absorption curve between TCR extract and protein fiber was shaped in the form of Langmuir adsorption isotherm. Fabric dyed without mordant was yellow in color, and when dyed with mordant, fabric showed various colors depending on mordant types except Sn. Color fastness to washing was generally fine and color fastness to light was moderate. But color fastness to rubbing and dry cleaning was outstanding. Lastly, dyed fabrics showed very good antimicrobial activity of 99.9% against Staphylococcus aureus and Kiebsiella pneumoniae.

TiO2 Nanoparticles from Baker's Yeast: A Potent Antimicrobial

  • Peiris, MMK;Guansekera, TDCP;Jayaweera, PM;Fernando, SSN
    • Journal of Microbiology and Biotechnology
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    • v.28 no.10
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    • pp.1664-1670
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    • 2018
  • Titanium dioxide ($TiO_2$) has wide applications in food, cosmetics, pharmaceuticals and manufacturing due to its many properties such as photocatalytic activity and stability. In this study, the biosynthesis of $TiO_2$ nanoparticles (NPs) was achieved by using Baker's yeast. $TiO_2$ NPs were characterized by X-ray Diffraction (XRD), UV-Visible spectroscopy, Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) and Energy Dispersive X-ray analysis (EDX) studies. The XRD pattern confirmed the formation of pure anatase $TiO_2$ NPs. According to EDX data Ti, O, P and N were the key elements present in the sample. SEM and TEM revealed that the nanoparticles produced were spherical in shape with an average size of $6.7{\pm}2.2nm$. The photocatalytic activity of $TiO_2$ NPs was studied by monitoring the degradation of methylene blue dye when treated with $TiO_2$ NPs. $TiO_2$ NPs were found to be highly photocatalytic comparable to commercially available 21 nm $TiO_2$ NPs. This study is the first report on antimicrobial study of yeast-mediated $TiO_2$ NPs synthesized using $TiCl_3$. Antimicrobial activity of $TiO_2$ NPs was greater against selected Gram-positive bacteria and Candida albicans when compared to Gram-negative bacteria both in the presence or absence of sunlight exposure. $TiO_2$ NPs expressed a significant effect on microbial growth. The results indicate the significant physical properties and the impact of yeast-mediated $TiO_2$ N Ps as a novel antimicrobial.

In Vitro Antioxidant Activities and Antimicrobial Activity of Lotus (Leaf, Stem, and Seed Pod) Extracts (연잎, 연 줄기 및 연자방 추출물의 In Vitro 항산화 활성과 항균 활성에 관한 연구)

  • Lee, Ki-Won;Kim, Yong-Hwan;Shin, Kyung-Ok
    • The Korean Journal of Food And Nutrition
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    • v.30 no.4
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    • pp.771-779
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    • 2017
  • The purpose of this study was to investigate and analyze the total phenolic content (TPC), antioxidant activities (FRAP, ABTS, and DPPH), and antibacterial properties of lotus (Nelumbo nucifera) extracts. Lotus leaves, stems, and seed pods were extracted with deionized water at $95^{\circ}C$, and with 70.5% ethanol at $85^{\circ}C$. The TPC ranged from 8.12 to 215.12 GAE mg/g. The ethanol extract of the seed pod had the highest TPC, and the TPC of the corresponding deionized water extract was 161.45 mg/g. FRAP values ranged from 104.03 to $3,546.39TEAC\;{\mu}mol/g$, ABTS radical cation scavenging activities ranged from 105.11 to $3,956.94TEAC\;{\mu}mol/g$, and DPPH radical scavenging activities ranged from 37.29 to $2,549.46TEAC\;{\mu}mol/g$. $EC_{50}$ values ranged from 0.26 to 9.63 mg/mL, and 0.31 to 21.21 mg/mL for ABTS and DPPH, respectively. The ethanol and deionized water extracts of the seed pod showed higher TPC and stronger antioxidant properties (FRAP, ABTS, and DPPH) than those of characteristic of the leaf extracts. The ethanol and deionized water extracts of the seed pod showed antimicrobial activity against Bacillus subtilis, Staphylococcus aureus, and Pseudomonas aeruginosa with inhibition zones of 9.0 to 14.0 mm, and the ethanol extract of the leaf showed antimicrobial activity against B. subtilis and S. aureus with inhibition zones of 9.0 and 10.0 mm, respectively. Thus, the lotus seed pod could be used to produce novel teas, and could be a potential source of therapeutic ingredients for food and medicine.

Antimicrobial and Antioxidant Properties of Secondary Metabolites from White Rose Flower

  • Joo, Seong-Soo;Kim, Yun-Bae;Lee, Do-Ik
    • The Plant Pathology Journal
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    • v.26 no.1
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    • pp.57-62
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    • 2010
  • Low-molecular-weight secondary metabolites from plants play an important role in reproductive processes and in the defense against environmental stresses or pathogens. In the present study, we isolated various volatiles and phenolic compounds from white Rosa rugosa flowers, and evaluated the pharmaceutical activities of these natural products in addition to their ability to increase survival in response to environmental stress and pathogen invasion. The DPPH and hydroxyl radical-mediated oxidation assay revealed that the white rose flower extract (WRFE) strongly scavenged free radicals in a dose dependent manner. Moreover, WRFE inhibited the growth of E. coli and fatally attacked those cells at higher concentration (>0.5 mg/mL). FITC-conjugated Annexin V stain provided further evidence that WRFE had strong antimicrobial activity, which may have resulted from a cooperative synergism between volatiles (e.g. 1-butanol, dodecyl acrylate and cyclododecane) and phenolic compounds (e.g. gallic acid) retained in WRFE. In conclusion, secondary metabolites from white rose flower hold promise as a potential natural source for antimicrobial and non-chemical based antioxidant agents.

Storage Ability of Packaging Paper by Thin Coating of Botanical Antimicrobial Agent (항균박막처리에 의한 포장지의 저장성 발현)

  • Kim Chul-Hwan;Moon Sang-Hwan;Huh Jeong-Soo;Cho Sung-Hwan;Kim Jae-Ok;Park Jong-Yawl;Kwon Oh-Chul
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.36 no.3
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    • pp.74-82
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    • 2004
  • The botanical antimicrobial agent prepared from citrus fruits (BAAC) was prepared to provide inhibitory ability to packaging paper The BAAC diluted in 0.5% and 1% starch solution respectively was applied to packaging paper by the thin coating technique. The antimicrobial packaging paper displayed great inhibitory effect against the putrefying microbes including fungi, yeast and bacteria. Tn addition to antimicrobial activity of the packaging papers, their physical properties such as tensile strength, burst strength, tear strength and bending stiffness could be improved by simultaneous treatment with starch. Both the item packaging by tissue paper and the outer packaging by corrugated boxes, which were treated by the thin coating of BAAC and starch, exhibited great ability in preserving freshness of stored mandann oranges. The more treatment of BAAC was made in the packaging paper, the greater freshness-preserving ability was generated.