• Journal of the Society of Cosmetic Scientists of Korea
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• v.47 no.1
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• pp.75-84
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• 2021

In this study, we investigated inhibitory effect of Tripeptide against particulate matter (PM)-induced damage in human keratinocytes. PM-induced cell death was inhibited by Tripeptide and the activity of aryl hydrocarbon receptor (AhR) also inhibited by Tripeptide resulting in reduced expression of its downstream targets, cytochrome P450 family 1 subfamily A member 1 (CYP1A1) and cyclooxygenase-2 (COX-2), which are responsible for toxic metabolites production and inflammation. Furthermore, PM-induced expressions of pro-inflammatory cytokines, matrix metalloproteinase-1 (MMP-1) and apoptosis-related factors were decreased by anti-oxidant activity of Tripeptide. From these results, it has been shown that the Tripeptide has protective effect against PM-induced skin damage not only through the inhibiting of keratinocyte death but also through the inhibiting the secretion of several damage-inducing factors to adjacent skin tissue. And the results suggested that Tripeptide with anti-pollution effect could be applied as a new functional cosmetic material.

• Journal of Applied Biological Chemistry
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• v.66
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• pp.213-220
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• 2023

The most common skin disease, acne, often occurs in adolescence, but it is also detected/observed in adults due to air pollution and drug abuse. One of the causative agents of acne, Cutibacterium acnes (C. acnes) plays a role in the development of skin acne by inducing inflammatory mediators. Torreya nucifera (TN) is an evergreen tree of the family Taxaceae, having well reported antioxidant, anti-proliferative, liver protection, and nerve protection properties. Improvement of these bioactive properties of natural products is one of the purposes of natural product chemistry and pharmaceuticals. We believe biorenovation could be one improvement strategy that utilizes microbial metabolism to produce unique derivatives having enhanced bioactivity. Therefore, in this study, the C. acnes-induced RAW264.7 inflammation model was used to evaluate the anti-inflammatory activity of the biorenovated Torreya nucifera product (TNB). The results showed improved viability of TNB-treated cells compared to TN-treated cells in the concentration range of 50, 100, and 200 ㎍/mL. At non-toxic concentrations, TNB inhibited the production of nitric oxide and prostaglandin E2 by suppression of inducible nitric oxide synthase and cyclooxygenase-2 protein expression. TNB also attenuated the expression of interleukin-1β, interleukin-6, interleukin-8, and tumor necrosis factor-α induced by C. acnes. Furthermore, TNB inhibited the nuclear factor-κB signaling pathway, a transcription factor known to regulate inflammatory mediators. Based on these results, this study suggests the potential of using TNB as natural material for the treatment of acnes and thus, supporting our postulation of biorenovation as an bioactivity improvement strategy.

• International Journal of Highway Engineering
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• v.18 no.3
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• pp.59-65
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• 2016

PURPOSES : This paper aims to develop a road pavement de-icing system using carbon sheet to replace the older snow de-icing method. Carbon sheet is a light and high-strength metal. Hence, various bodies of research for its applications in many industries have progressed. METHODS : The experiment was conducted in a laboratory. The carbon sheet supplied voltage through a power supply system, and produced heat transfers to the concrete surface. Various factors, such as pavement material, carbon sheet width, penetration depth, and freezing-thawing resistance, were considered in the conducted experiments to confirm the heating transfer efficiency of the carbon sheet. RESULTS : The carbon sheet used was a conductor. Therefore, it produced heat if voltage was supplied. The exposed carbon sheet on the atmosphere did not affect the carbon sheet width when it provided constant voltage. However, the sheet showed different heating behaviors by width change when the carbon sheet penetrated into the concrete. Moreover, the freezing-thawing resistance was decreased by the carbon sheet with increasing width. CONCLUSIONS : The experiments confirmed the possibility of developing a road snow melting system using a carbon sheet. The antiicing system using the carbon sheet to replace the traditional anti-icing system has disadvantages of environmental pollution risk and electric leakage. The pavement also improved its toughness resistance. The utilization value will be very high in the future if carbon sheet heat loss can be minimized and durability is improved.

• Journal of Astronomy and Space Sciences
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• v.31 no.4
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• pp.325-333
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• 2014

We are motivated by both the accumulating evidence for the connection of solar variability to the chemistry of nitrogen oxide in the atmosphere and recent finding that the Galactic cosmic-ray (GCR) influx is associated with the solar north-south asymmetry. We have analyzed the measured pH in precipitation over the 109 stations distributed in the United States. We have found that data of pH in precipitation as a whole appear to be marginally anti-correlated with the solar asymmetry. That is, rain seems to become less acidic when the southern hemisphere of the Sun is more active. The acidity of rain is also found to be correlated with the atmospheric temperature, while not to be correlated with solar activity itself. We have carried on the analysis with two subsamples in which stations located in the east and in the west. We find that the pH data derived from the eastern stations which are possibly polluted by sulfur oxides and nitrogen oxides are not correlated with the solar asymmetry, but with the temperature. On the contrary, the pH data obtained from the western stations are found to be marginally anti-correlated with the solar asymmetry. In addition, the pH data obtained from the western stations are found to be correlated with the solar UV radiation. We conclude by briefly pointing out that a role of the solar asymmetry in the process of acidification of rain is to be further examined particularly when the level of pollution by sulfur oxides and nitrogen oxides is low.

• ALGAE
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• v.32 no.3
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• pp.261-273
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• 2017

Fine dust (FD) particles have become a major contributor to air pollution causing detrimental effects on the respiratory system and skin. Although some studies have investigated the effects of FD on the respiratory system, their possible effects on the skin remain under-explored. We investigated the FD mediated inflammatory responses in keratinocytes, present in the outer layers of skin tissues and the transfer of inflammatory potential to macrophages. We further evaluated the anti-inflammatory effects of the polyphenolic derivative, diphlorethohydroxycarmalol (DPHC) isolated from Ishige okamurae against FD-induced inflammation. Size distribution of FD particles was analyzed by scanning electron microscopy. FD particles induced the production of cyclooxygenase-2, prostaglandin E2 ($PGE_2$), interleukin (IL)-$1{\beta}$, and IL-6 in HaCaT keratinocytes and the expression of nitric oxide (NO), inducible nitric oxide synthases (iNOS), $PGE_2$, tumor necrosis factor-${\alpha}$ expression in RAW 264.7 macrophages. Further, we evaluated the inflammatory potential of the culture medium of inflammation-induced HaCaT cells in RAW 264.7 macrophages and observed a marked increase in the expression of NO, iNOS, $PGE_2$, and proinflammatory cytokines. DPHC treatment markedly attenuated the inflammatory responses, indicating its effectiveness in suppressing a broad range of inflammatory responses. It also showed anti-inflammatory potential in in-vivo experiments using FD-stimulated zebrafish embryos by decreasing NO and reactive oxygen species production, while eventing cell death caused by inflammation.

• Journal of Advanced Marine Engineering and Technology
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• v.39 no.9
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• pp.981-986
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• 2015

As the seriousness of global environment pollution is gaining increasing public attention, research into greenhouse gas emissions of ships is being carried out globally. At a domestic level, however, in a number of significant fields such research has not been conducted to date. This study examined countermeasures for the reduction of $CO_2$ emission in the fields of electronic control engines, trim optimization, propeller polishing, hull cleaning, and anti-fouling paint using an actual sea-going vessel. Selected countermeasures were applied during sea trials of the ship and the effect of specific fuel oil consumption analyzed. It was found that each countermeasure resulted in a decrease of fuel consumption of 1~5%. The energy efficiency operational indicator (EEOI) was calculated and found to also be improved by 1~5%. Further research into the EEOI of domestic shipping is planned to enhance conformance with international environmental regulations and improve global competitiveness.

• Proceedings of KOSOMES biannual meeting
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• 2006.11a
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• pp.97-104
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• 2006

Though stringent guidelines are in place to protect the harbor environment, pollution from ships, from the ports terminals. Discharge from the ballast tanks of ships, though illegal, does occur. Such vessels, arriving from distant ports of call, can introduce exotic species of plants and animals, causing disruption of the local food web. Discharges rich in nitrogen can generate the rapid growth of plankton, eventually leading to a condition known as red tide that is lethal to some coastal organisms. In addition to the harbor's negative effects on marine organisms, the diesel engines of the ships and the trucks that haul cargo to and from the ports release large volumes of diesel exhaust into the atmosphere. IMO(International Maritime Organization) is strongly proceeding with adoption of a new maritime environment convention and coming into effect for regulation enhancement about the pollutants which are happened in a ship recently. Study about the conventions that our country currently comes into effect, and there is during forwarding and correspondence must be performed effectively. In this paper, International convention on the control of harmful Anti-Fouling system on ship, Ballast water management, Prevention of air pollution from ships, treat a main pending problem in ocean related environmental regulation convention.

• Korean Journal of Construction Engineering and Management
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• v.6 no.5 s.27
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• pp.186-192
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• 2005

The purpose of this study is to find the reality of environmental management cost in construction projects and to suggest some policies in order that owners appropriate the environmental management cost reasonably in the construction budget for reducing the environmental pollution at job sites. We surveyed the actual state of appropriating and expending the environmental management cost over 122 construction sites. According to the results of the survey, while the appropriated rate of the environmental management cost was 0.59% of the total construction cost. the expended rate reached at 0.94%. When examining the antipollution facilities which were operated in job sites, the investment for equipment against air-pollution such as tire washer, dust-proof device was relatively higher than other antipollution equipment. As the method appropriating the environmental management cost, we concluded that a quantity-per-unit costing method is more reasonable than appropriating at a fixed rate of total construction cost considering that there is little correlation between total construction cost and the environmental management cost. To do so, antipollution facilities that must be examined at a design or estimation stage of a construction project should be prescribed by the law. Moreover, referenced cost data for the quantity-per-unit costing should be prepared and officially published.

• Journal of environmental and Sanitary engineering
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• v.24 no.1
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• pp.1-12
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• 2009

The various environmental problems that we face on today are basically about environmental quality. Since early 1960s affluent material was produced because of remarkable economic growth by many cooperations. However, for the lack of environmental policy, environmental pollutions has been serious. The central government should transfer the producing and consuming structure to environmental affinity through the regulations for developing Korea as a model of environmental nation which takes an active part in global environmental programme and in which the environment and economy are well harmonized. Moreover, the central government should take the lead in prevention of environmental pollution through the direct policies such as strengthening the discharge limit or setting up environmental basic institutions by securing budget for conserving environment. This thesis emphasize on the public institution among many environmental basic institutions for environmental anti-pollution project. It will find the problems with running those institutions, and will suggest the preview of improvement. Also, it is necessary to investigate of variation trend for inflow and pollutant loading to environmental infrastructure as increased of the diffusion rate as established and maintenance of sewer system. The purpose of this study is to investigate for inflow and pollutant loading to environmental infrastructure, and also to provide the method of efficiently maintenance and management. The results obtained were summarized as follows; 1. Survey of actual condition on operation and management of environmental infrastructure was evaluated the propriety of treatment process and problem of plant management. 2. Analysis of pollutant loading contribution for river system of environmental infrastructure with data analysis of water quality measuring network. 3. To investigate on case study for efficiently maintenance and management of environmental infrastructure. The result on this study was provide the method of efficiently maintenance and management with survey for establish and repair of sewer system and survey of actual condition on operation and management of environmental infrastructure in the water area of discharge to Geum River System. Application as guideline for establish and management of environmental infrastructure, and management of Geum River System. Also, application for preliminary data for fulfill-assess of total effluent regulation of water pollution.

• Proceedings of the KIEE Conference
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• 1999.07d
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• pp.1621-1623
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• 1999

Recently, high voltage outdoor ploymer insulators have been widely used commercially owing to their excellent electrical and mechanical properties, superior comtamination flashover performance, light weight, easy installation or handing, no maintenance during service, competitive price and so on. compared to porcelaain and glass insulators. For instance, silicone rubber(SR) for polymeric insulators specially has much superior insulating and anti-pollution performance due to its specific hydrophobicity even in severe contaminated environments. We have investigated surface discharge current characteristics of silicone rubbers(SR) for HV outdoor composite insulation specimen under accelerated aging codition using a computer measuring system. The relations of average leakage current and surface discharge current repetition rates and discharge current amplitude, the distribution of discharge current amplitude were studied to investigate electrical conduction of silicone rubber surface with the salt fog condition.