• Title/Summary/Keyword: anthraquinone derivatives

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Antioxidant Activity of Anthraquinones from Morinda elliptica

  • Ismail, Nor Hadiani;Mohamad, Habsah;Mohidin, Amran;Lajis, Nordin Hj.
    • Natural Product Sciences
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    • v.8 no.2
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    • pp.48-51
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    • 2002
  • Antioxidative properties of fifteen anthraquinone derivatives, including eleven atural anthraquinones isolated from the roots of Morinda elliptica and four from synthetic origin were evaluated using thin layer chromatography (TLC), ferric thiocyanate (FTC) and thiobarbituric acid (TBA) methods. Five of the compounds, nordamnacanthal, damnacanthal, 2-formyl-1-hydroxyanthraquinone, morindone and alizarin showed higher antioxidative activity than standard natural antioxidant, ${\alpha}-tocopherol$, on the FTC assay. Morindone and alizarin showed the strongest antioxidant activity. The results from the bioassay using TBA method correlated well with the results of the FTC method.

Production of Anthraquinone Derivatives by Rubia cordifolia var. pratensis Transformed by Agrobacterium spp (Agrobacterium으로 형질전환시킨 갈퀴꼭두선이의 세포배양에 의한 천연염료생산)

  • Shin, Soon-Hee;Kim, You-Sun;Kim, Seung-Hye
    • Korean Journal of Pharmacognosy
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    • v.23 no.3
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    • pp.137-141
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    • 1992
  • The cells of Rubia cordifolia var. pratensis were transformed by Agrobactrium tumefaciens strain 11157. Surface-sterilized young leaves and stems of the plants were cocultivated with bacterial suspensions. Crown galls induced from stems were cultured with variation of culturing conditions and compared with untransformed cells. The growth rates and production of anthraquinone pigments of cells were remarkably improved by transformation. Furthermore, hairy roots were induced by inoculation or cocultivation with Agrobacterium rhizogenes strains.

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Characterization of Anthraquinone-Based Electron Acceptors for Organic Solar Cells (유기태양전지용 안트라퀴논 기반 전자 받게 분자의 특성 분석)

  • Hyun, Chang-Seok;An, Byeong-Kwan
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.35 no.4
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    • pp.366-371
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    • 2022
  • Recently many efforts have been made to develop a novel class of non-fullerene electron acceptor materials for high-performance organic solar cells. In this work, anthraquinone derivatives, TMAQ and THAQ, were prepared and their availability as electron acceptor materials for organic solar cells were investigated in terms of optical, thermal, electrochemical properties, and solar cell devices. Compared to TMAQ, a significant bathochromic shift of absorption band was observed for THAQ owing to intramolecular hydrogen-bond-assisted CT interactions. Thanks to the fused aromatic ring structure and benzoquinone unit, both TMAQ and THAQ exhibited a high thermal stability and an efficient electron reduction process. In particular, the intramolecular O-H---O=C hydrogen bond of THAQ plays an important role in improving the thermal stability and electron reduction properties. In the P3HT:acceptor solar cell system, THAQ-based devices had more than ca. 6 times higher power conversion efficiency than TMAQ -based devices. These results serve as a guide for developing high-efficient anthraquinone-based electron acceptor materials.

Anthraquinones from the Rhizome of Polygonum sachalinense (왕호장근의 성분 연구)

  • 지형준;문희수;이용주
    • YAKHAK HOEJI
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    • v.27 no.1
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    • pp.37-43
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    • 1983
  • The rhizome of Polygonum sachalinense Fr. Schm. (=Reynoutria sachalinensis Nakai, Polygonaceae) has been used as "Polygoni Rhizoma" (Hu Zhang) in the Orient as laxatives, diuretics and for treatment of suppurative dermatitis, gonorrhoea, favus and athlete's foot. From the methanolic extract of the dried rhizome physcion, emodin, emodin-8-O-$\beta$-D-glucoside as anthraquinone derivatives and .betha.-sitosterol glucoside were isolated and identified. Stilbene derivatives which have antibacterial and antifungal activities were also isolated.

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Isolation of Anthraquinone Derivatives from the Root of Rumex japonicus H. (참소리쟁이 뿌리에서 안트라퀴논계 화합물의 분리 및 생리활성)

  • Hwang, Seon-Woo;Ha, Tae-Joung;Lee, Jong-Rok;Lee, Jun;Nam, Sang-Hae;Park, Ki-Hun;Yang, Min-Suk
    • Applied Biological Chemistry
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    • v.47 no.2
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    • pp.274-278
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    • 2004
  • Four anthraquinone derivatives were isolated from the root of Rumex japonicus Houtt. These compounds were identified as physcion, emodin, chrysophanol-10,10'-bianthrone and $physcion-10,10'-bianthrone^(a)$, respectively. The last compound (a), especially, showed strong activity against A549, PC-3, UO-31 and HCT-15 human cancer cell lines with $IC_{50}$ values, ranging from 0.45 to $1.33\;{\mu}g/ml^{-1})$.

Quantitative Analysis of Anthraquinone and Stilbene Derivatives in Various Rhubarbs (대황류 생약의 인트라퀴논 및 스틸벤 유도체 함량분석)

  • Ko, Sung-Kwon;Han, Sung-Tai;Yang, Byung-Wook;Shin, Cha-Gyun;Hahm, Young-Tae;Cho, Soon-Hyun;Whang, Wan-Kyun
    • Korean Journal of Pharmacognosy
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    • v.36 no.4 s.143
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    • pp.257-262
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    • 2005
  • This study was carried out to obtain the basic information that can be used to index rhubarbs in six regions of China and Korea. The anthraquinone and stilbene contest in various rhubarb produced in th different area were quantitatively analysed by HPLC. The average of sennoside A content of the Chinghai rhubarb was higher than that of the other palmata rhubarbs(high-quality rhubarbs) produced in China. As a result, the order of the sennoside A content was 1) Chinghai rhubarb, 2) Tsuchan rhubarb, 3)Kansu rhubarb 4) Neimenggu rhubarb. On the other hand, the total stilbenes content of each of the cultivated Korean rhubarb(Rheum undulatum) were higher than that of the Chinese rhapontica rhubarb(low-quality rhubarbs).

Pharmacognostical Studies on Ha-Su-O(Polygoni Radix) (하수오류(何首烏類)의 생약학적 연구)

  • Han, Dae-Suk
    • Korean Journal of Pharmacognosy
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    • v.4 no.2
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    • pp.83-94
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    • 1973
  • Experiments were carried out to evaluate the pharmacognostical aspects of Polygoni Radix which consists of the roots of Polygonum multiflorum $T_{HUNBERG}$(Polygonaceae), Cynanchum wilfordii $H_{EMSLEY}$ (Asclepiadaceae) and Polygonum ciliinerve $(N_{AKAI})O_{WI}$ (Polygonaceae), since it was known to be effective as tonic, nutrient, etc. in oriental medicine. The histological features of the above three plants of Polygoni Radix were compared in view point of external and internal morphologies and their habitats. Also their constituents were compared on the basis of anthraquinone group. From the methanol extract of Polygonum ciliinerve $(N_{AKAI})O_{WI}$, furthermore, a specific product of this country, two anthraquinone derivatives were isolated. One of the substances was identified as emodin $(C_{15}H_{10}O_5,\;m.p.\;268-269^{\circ})$ through comparison of the authentic compound and spectroscopy.

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5-Arylidene-2(5H)-Furanone Derivatives: Synthesis and Structure-Activity Relationship for Cytotoxicity

  • Bang, Seong-Cheol;Kim, Yong;Yun, Mi-Young;Ahn, Byung-Zun
    • Archives of Pharmacal Research
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    • v.27 no.5
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    • pp.485-494
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    • 2004
  • Thirty-eight 5-arylidene-2(5H)-furanone derivatives possessing halo-, methoxy-, oxo-, dioxo-, and thiophenyl groups as well as anthraquinone and naphthquinone moieties were synthesized, and their cytotoxicity was evaluated against various cancer cell lines. The introduction of halogen atoms or nitro group at aromatic ring of 5-arylidene-2(5H)-furanone was shown to increase the cytotoxicity with 5-(3-nitrobenzylidene )-2(5H)-furanone (21) being the most potent. Among anthracenyl or naphthalenyl derivatives, (E)-5-[2-(1 ,4-dimethoxy-9, 10-dioxo) anthracenyl]-2(5H)-furanone (34) showed the most potent cytotoxic activity.

Coloration of Pure Polypropylene Fiber with Super Hydrophobic Dyes; Application of Anthraquinone Derivatives with linear Alkyl Substituents

  • Kim, Tae-Kyeong;Yoon, Seok-Han;Hong, Jin-Pyo;Kim, Hong-Je;Bae, Jin-Seok
    • Textile Coloration and Finishing
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    • v.18 no.5 s.90
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    • pp.30-34
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    • 2006
  • Polypropylene fiber was dyed with 4 super hydrophobic dyes having different alkyl derivatives on the same chromophore. Double-tailed cationic surfactant, didodecyldimethylammonium bromide(DDAB), was used to make dye-dispersant complex to improve the dispersion of dyes. As the alkyl groups are longer and the hydrophobicity is increased, the dyeability onto polypropylene fiber was improved and deep coloration was obtained. As for the fastness properties, wash fastness was relatively good, while light fastness was bit low.