Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Antioxidant Activity of Anthraquinones from Morinda elliptica

  • Ismail, Nor Hadiani (Institute of Bioscience, Universiti Putra Malaysia,Faculty of Applied Science, Universiti Teknologi MARA) ;
  • Mohamad, Habsah (Institute of Bioscience, Universiti Putra Malaysia) ;
  • Mohidin, Amran (Institute of Bioscience, Universiti Putra Malaysia) ;
  • Lajis, Nordin Hj. (Institute of Bioscience, Universiti Putra Malaysia)
  • Published : 2002.06.01
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Abstract

Antioxidative properties of fifteen anthraquinone derivatives, including eleven atural anthraquinones isolated from the roots of Morinda elliptica and four from synthetic origin were evaluated using thin layer chromatography (TLC), ferric thiocyanate (FTC) and thiobarbituric acid (TBA) methods. Five of the compounds, nordamnacanthal, damnacanthal, 2-formyl-1-hydroxyanthraquinone, morindone and alizarin showed higher antioxidative activity than standard natural antioxidant, ${\alpha}-tocopherol$, on the FTC assay. Morindone and alizarin showed the strongest antioxidant activity. The results from the bioassay using TBA method correlated well with the results of the FTC method.

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References

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