• Title/Summary/Keyword: annulus

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In-Vitro Model Design of Mitral Valve Regurgitation and Comparative Study of Quantification between PISA and 4D flow MRI (승모판 역류 In-Vitro 모델을 활용한 초음파 및 4D flow MRI 기반 혈류 정량화 비교연구)

  • Juyeon Lee;Minseong Kwon;Hyungkyu Huh
    • Journal of the Korean Society of Visualization
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    • v.22 no.1
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    • pp.40-48
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    • 2024
  • This study presents an in-vitro model designed to simulate mitral valve regurgitation, aiming to compare the quantification results between Proximal Isovelocity Surface Area(PISA) and 4D Flow MRI on both fixed and valve annulus tracking(VAT) views. The in-vitro model replicates the dynamic conditions of the mitral valve in a pulsatile environment, utilizing a piston pump set at 60 bpm. Through systematic experiments and analysis, the study evaluates the accuracy and effectiveness of PISA and 4D Flow MRI in assessing regurgitation severity, considering both fixed and valve annulus tracking. The displacement length measured in echo closely resembled that of optical measurements, making it advantageous for structural analysis. VAT-4D flow MRI exhibited the smallest deviation from actual flow rate values, establishing it as most accurate method for quantitative regurgitation assessment.

Biodisc Regeneration Using Annulus Fibrosus Cell with Hyaluronic Acid Impregnated Small Intestinal Submucosa Sponge (히알루론산이 함유된 SIS 스폰지와 섬유륜세포를 이용한 디스크재생)

  • Hong, Hee-Kyung;Lee, Seon-Kyoung;Song, Yi-Seul;Kim, Dae-Sung;Eom, Shin;Kim, Hyoung-Eun;Lee, Dong-Won;Khang, Gil-Son
    • Polymer(Korea)
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    • v.34 no.3
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    • pp.282-288
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    • 2010
  • The porcine small intestinal submucosa (SIS) has been widely used as a biomaterial without immuno rejection responses and hyalunonic acid (HA) can be used as biocompatible materials to regenerate tissue. We developed the SIS sponge and HA loaded SIS sponges (SIS/HA) for the possibility of the application of the tissue engineering using annulus fibrosus (AF). SEM observation shows that SIS and SIS/HA sponges have interconnected and open pores. We demonstrated the presence of HA in SIS/HA sponge from C-O functional group observed by the FTIR analysis. In conclusion, we suggest that SIS/HA sponge may be useful to tissue engineering using AF cell. This may be due to the enhanced biocompatibility and higher water retention capacity of HA.

Evaluation of Various Scaffolds for Tissue Engineered Biodisc Using Annulus Fibrosus Cells (조직공학적 바이오디스크의 섬유륜 재생을 위한 지지체 특성평가)

  • Ha, Hyun-Jung;Kim, Soon-Hee;Yoon, Sun-Jung;Park, Sang-Wook;So, Jung-Won;Kim, Moon-Suk;Rhee, John-M.;Khang, Gil-Son;Lee, Hai-Bang
    • Polymer(Korea)
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    • v.32 no.1
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    • pp.26-30
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    • 2008
  • This study was designed to investigate the effect of hybridization of synthetic/natural materials for annulus fibrosus (AF) tissue regeneration in vitro and in vivo. The synthetic/natural hybrid scaffolds were prepared using PLGA (poly (lactic-co-glycolic) acid), SIS (small intestinal submucosa) and DBP (demineralized bone particles). PLGA, PLGA/SIS(20%), PLGA/DBP(20%) and PLGA/SIS (10%)/DBP (10%) scaffold were manufactured by solvent casting/salt leaching method. Compressive strength was measured. Rabbit AF cells were isolated, cultured and seeded into experimental groups. Hydroxyproline production and DNA quantity of AP cells on each scaffold was measured at 2, 4 and 6 weeks after in vitro culture. Cell-scaffold composites were implanted subcutaneously into athymic mice. After 1,4 and 6 weeks postoperatively, specimens were taken and H&E, Safranin-O and type I collagen staining were carried out concerning formation of cartilagenous tissue. In vitro PLGA/SIS scaffold was evaluated for total collagen content (bydroryproline/DNA content) and PLGA scaffold was evaluated for compressive strength.

Studies on the Structure and Production Processes of Biotic Communities in the Coastal Shallow Waters of Korea 3. Age and Growth of Spisula sachalinensis from the Eastern Waters of Korea (한국연안천해생물군집의 구조와 생산 3. 동해산 북방대합 (Spisula sachalinensis)의 연령과 성장)

  • KANG Yong Joo;KIM Chong Kawn
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.16 no.2
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    • pp.82-87
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    • 1983
  • The aging and growth of Spisula sachalinensis from Ingu over the period from December 1981 through November 1982 were studied. The rings on the shell were used as the character for age determination. The ring where the translucent zone shifts to the opaque one was regarded as an annulus. The time of its formation was estimated by monthly variations of marginal growth rate in the shell. It was formed once a year over the period from August through September. The shell length at the formation of the annulus was estimated by taking the mean shell length corresponding to each of the annual ring. From analysis of mean shell length at the formation of the annulus, von Bertalanffy's growth equation was estimated as follows; $l_t=126.38(1-e^{-0.262(t-0.656)})\;W_t=485.85(1-e^{-0.262(t-0.656)})^3$ Back-calculated shell lengths estimated from this equation was quite consistent with actual shell lengths.

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The Mechanical Sensitivity at Interfaces between Bone and Interbody Cage of Lumbar Spine Segments (Lumbar spine 의 뼈와 Interbody cage의 접촉면에서 기계공학적 민감성 고찰)

  • Kim Y.
    • Journal of Biomedical Engineering Research
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    • v.21 no.3 s.61
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    • pp.295-301
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    • 2000
  • It is known that among many factors, relative micromotion at bone/implant interfaces can hinder bone ingrowth into surface pores of an implant. Loading conditions, mechanical properties of spinal materials, friction coefficients at the interfaces and geometry of spinal segments would affect the relative micromotion and spinal stability. A finite clement model of the human lumbar spine segments (L4-L5) was constructed to investigate the mechanical sensitivity at the interfaces between bone and cage. Relative micromotion. Posterior axial displacement. bone stress, cage stress and friction force were predicted in changes of friction coefficients, loading conditions. bone density and age-related material/geometric properties of the spinal segments. Relative micromotion (slip distance in a static loading means relative micromotion in routine activity) at the interfaces increased significantly as the mechanical properties of cancellous bone, annulus fibers or/and ligaments decrease or/and as the friction coefficient at the interfaces decreases. The contact normal force at the interfaces decreased as cancellous bone density decreases or/and as the friction coefficient increases A significant increase of slip distance at anterior annulus occurred with an addition of torsion to compressive preload. Relative micromotion decreased with an increase of disc area. In conclusion. relative micromotion, stress response. Posterior axial displacement and contact normal force are sensitive to the friction coefficient of the interfaces, bone density, loading conditions and age-related geometric/material changes.

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Fast Pyrolysis Characteristics of Jatropha Curcas L. Seed Cake with Respect to Cone Angle of Spouted Bed Reactor (분사층 반응기의 원뿔각에 따른 Jatropha Curcas L. Seed Cake의 급속열분해 특성)

  • Park, Hoon Chae;Lee, Byeong-Kyu;Kim, Hyo Sung;Choi, Hang Seok
    • Clean Technology
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    • v.25 no.2
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    • pp.161-167
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    • 2019
  • Several types of reactors have been used during the past decade to perform fast pyrolysis of biomass. Among the developed fast pyrolysis reactors, fluidized bed reactors have been widely used in the fast pyrolysis process. In recent years, experimental studies have been conducted on the characteristics of biomass fast pyrolysis in a spouted bed reactor. The fluidization characteristics of a spouted bed reactor are influenced by particle properties, fluid jet velocity, and the structure of the core and annulus. The geometry of the spouted bed reactor is the main factor determining the structure of the core and annulus. Accordingly, to optimize the design of a spouted bed reactor, it is necessary to study the pyrolysis characteristics of biomass. However, no detailed investigations have been made of the fast pyrolysis characteristics of biomass in accordance with the geometry of the spouted bed reactor. In this study, fast pyrolysis experiments using Jatropha curcas L. seed shell cake were conducted in a conical spouted bed reactor to study the effects of reaction temperature and reactor cone angle on the product yield and pyrolysis oil quality. The highest energy yield of pyrolysis oil obtained was 63.9% with a reaction temperature of $450^{\circ}C$ and reactor cone angle of $44^{\circ}$. The results showed that the reaction temperature and reactor cone angle affected the quality of the pyrolysis oil.

Injectable Hydrogel as an Artificial Nucleus Pulposus in a Degenerative Intervertebral Disc (Injectable Hydrogel을 이용한 인공 Nucleus Pulposus의 제조)

  • Park, Jin-Hyun
    • Proceedings of the Korean Fiber Society Conference
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    • 2002.04a
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    • pp.13-16
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    • 2002
  • The Intervertebral disc is a composite structure made up of the nucleus pulposus (NP) core surrounded by the multi-layered fibers of the annulus fibrosis (AF)[1]. Water is drawn into the NP by the presence of hydrophilic proteins called proteoglycans [2]. The AF, with successive layers oriented in alternating directions, surrounds the NP. These layers are placed under tension as the NP absorbs water and swells [3]. (omitted)

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TCE degradation by a photocatalysis in the annular flow & the annulus fluidized bed photoreactor (애뉼러 흐름 및 애뉼러스 유동층 광반응기에서 Trichloroethylene 의 광촉매 분해반응 특성)

  • 임탁형;김상돈
    • Proceedings of the Korea Society for Energy Engineering kosee Conference
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    • 2002.11a
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    • pp.161-164
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    • 2002
  • 대기로 배출되는 휘발성 유기화합물 중의 하나인 TCE (Trichroloethylene)를 제거하는 기술들은 설치비 및 운전비가 많이 요구되는 흡착, 응축, 소각기술 들이 있으며, 이를 대체하는 신기술로 광촉매 반응으로 유기휘발물을 상온과 상압에서 광반응시켜 제거함으로서, 설치 및 조업비 측면에서 경제적인 이점이 있다.(중략)

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Surgical Treatment of Ebstein`s Anomaly Report of a case (Ebstein 심기형의 개심술 1례)

  • Park, Guk-Yang;Lee, Jeong-Ho;Yu, Hoe-Seong
    • Journal of Chest Surgery
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    • v.18 no.3
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    • pp.436-439
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    • 1985
  • A patient of Ebstein`s anomaly underwent surgical repair on Oct. 24th, 1984. Tricuspid valve was replaced by 31mm St. Jude mechanical valve without plication of atrialized right ventricle. The annulus has been placed below the coronary sinus, with care not to damage the conduction system. But postoperatively complete heart block developed. Permanent pacemaker was implanted on his 12th POD. Now he has been followed up for 9 months. There was no hemodynamic problems yet.

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Syphilitic Ascending Aortic Aneurysm - A Case Report - (매독성 상행 대동맥류 수술치)

  • Lee, Sin-Yeong;Gang, Jeong-Ho;Ji, Haeng-Ok
    • Journal of Chest Surgery
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    • v.20 no.1
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    • pp.182-186
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    • 1987
  • The incidence of syphilitic aortic aneurysm was decreased now a day. We experienced a case of huge syphilitic ascending aortic aneurysm from just above portion of aortic annulus to about 1 cm below innominate artery without aortic insufficiency. Surgical correction was done by replacement of ascending aorta with woven Dacron graft under cardiopulmonary bypass. Postoperative course was uneventful and discharged 15 days after surgery with good condition.

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