Journal of the Korean Society of Visualization (한국가시화정보학회지)

The Korean Society of Visualization (한국가시화정보학회)
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In-Vitro Model Design of Mitral Valve Regurgitation and Comparative Study of Quantification between PISA and 4D flow MRI

승모판 역류 In-Vitro 모델을 활용한 초음파 및 4D flow MRI 기반 혈류 정량화 비교연구

  • Juyeon Lee (Department of Mechanical & Biomedical Engineering, University of Kangwon) ;
  • Minseong Kwon (Department of Mechanical & Biomedical Engineering, University of Kangwon) ;
  • Hyungkyu Huh (Medical Device Development Center, Daegu Gyeongbuk Medical Innovation Foundation)
  • Received : 2024.02.21
  • Accepted : 2024.03.14
  • Published : 2024.03.31
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Abstract

This study presents an in-vitro model designed to simulate mitral valve regurgitation, aiming to compare the quantification results between Proximal Isovelocity Surface Area(PISA) and 4D Flow MRI on both fixed and valve annulus tracking(VAT) views. The in-vitro model replicates the dynamic conditions of the mitral valve in a pulsatile environment, utilizing a piston pump set at 60 bpm. Through systematic experiments and analysis, the study evaluates the accuracy and effectiveness of PISA and 4D Flow MRI in assessing regurgitation severity, considering both fixed and valve annulus tracking. The displacement length measured in echo closely resembled that of optical measurements, making it advantageous for structural analysis. VAT-4D flow MRI exhibited the smallest deviation from actual flow rate values, establishing it as most accurate method for quantitative regurgitation assessment.

Keywords

Acknowledgement

This research was supported by National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (NRF-2021R1C1C1003481).

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