• Journal of Korean Medical Ki-Gong Academy
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• v.20 no.1
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• pp.118-147
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• 2020

Objective : The purpose of this study is to understand trends of pelvic correction therapy in Korea and to assist research activities on pelvic correction therapy. Also, this study selected and presented indicators for measuring pelvic slope to help ensure consistent studies with uniform indicators in future studies related to pelvic correction. Methods : The following keywords "골반", "골반 교정", "골반 변위" "Pelvic correction" were searched on three specialized search sites (RISS, NAI, DBpia). Trends in pelvic correction therapy were analyzed through the selected researches suitable among these searched researches in an overview format. Results : 1. A total of 7,806 studies were searched and a total of 268 studies were finally selected. 2. Studies began in 1977 and have been actively studied until recently, with 35 studies in 2017 being the most recent trend since 2000. 3. In the results according to the Main Field of Research, the 'Arts and Kinesiology'(113, 42.16%) and 'Medicine and Pharmacy'(103, 38.43%) were the most in order. To the Middle Field, the 'Kinesiology was the largest with 96(35.82%) studies. 4. In the results according to the study design, 'Pre-Post Test(PPT)' was the largest with 107 studies. 5. In the results according to the Intervention, 'Exercise' was the largest with 165 studies, of which 'Pilates' and 'Yoga' in 'Training' was the largest. 6. Among the evaluation method, the 'Pelvic Index' was used 146 times, followed by 'Spinal Alignment (99)', 'Other Joints (93)', and 'Kinetic Specialized Measurement Test (56)'. 7. Among the evaluation methods, the pelvic slope measurement indicators were PT (58), PH (48), Pelvic Torsion (40), Iliac Crest (38), ASIS-PSIS distance/angle (27), and Pelvic Width (I.W., I.L., S.W) (25) in order. 8. The journals that published the most researches were KJSS(Korean Alliance For Health, Physical Education, Recreation, And Dance;9), and JKPT(Korean Physical Therapy;9). Among the University, the Graduate School of Silla University published the most papers (12). 9. The author who published the most studies were Seungjin Park(3), the co-authors were Hoseong Lee, Gideok Park, Seongsu Bae(3), and the Thesis-Director Gyeongok Lee(7). Conclusions : 1. Studies on pelvic correction treatment continue to increase every year. 2. The main academic field of pelvic correction is 'Sports', 'Physical Therapy', and 'Medical Science'. 3. The most chosen research design method in the study on pelvic correction treatment was 'Pre-Post Test(PPT)', primarily as an intermediary, Pilates and yoga during exercise therapy, and then Chiropractic during handcraft were used as multiple frequencies. 4. Among the various measurement method indicators of pelvic correction previously used, multiple frequency was taken up in the order of PT, PH, Pelvic Torsion, iliac crest, ASIS-PSIS distance/angle, and pelvic width (I.W.,I.L.,S.W). Typically, measurements through "ASIS-PSIS angle" are recommended and are considered as the most rational in clinical trials.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.6
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• pp.413-419
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• 2021

The purpose of this study was to investigate the ability to treat and prevent infection by multiple Gram-negative bacterial pathogens as a last choice option in the treatment of serious infections in clinical settings. The global spread of extended-spectrum 𝛽-lactamases (ESBLs) and/or carbapenemases in microorganisms are of enormous concern to health services because they are often associated with multi-drug resistance which significantly restricts the antibiotic treatment options. In this study, the antimicrobial resistance profiles of bacteria isolated from South Korean market-derived meat samples were determined by the disc diffusion method. PCR was used to detect the presence of antibiotic resistance genes and ESBL producing genes. In total, we tested 181 isolated colonies from 36 market-derived meat samples. Single PCR and DNA sequencing results revealed that genes blaVIM, blaBIC, blaKPC, and blaSIM were present in the bacteria isolated from retail meat. The bacteria in the meat were separately sequenced and based on alignment, four different bacteria were identified. These findings suggest that bacteria found in retail meats are a reservoir for the spreading of ESBL blaVIM, blaBIC, blaKPC, and blaSIM resistance genes and bacteria strains.

• Animal Bioscience
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• v.34 no.4
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• pp.546-557
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• 2021

Objective: If fertilization does not occur within a specific period, the quality of unfertilized oocytes in the oviduct (in vivo aging) or in culture (in vitro aging) will deteriorate over time. Icariin (ICA), found in all species of Epimedium herbs, has strong antioxidant activity, and is thought to exert anti-aging effects in vitro. We asked whether ICA protects oocytes against age-related changes in vitro. Methods: We analyzed the reactive oxygen species (ROS) levels and expression of antioxidant, maternal, and estrogen receptor genes, and along with spindle morphology, and the developmental competence and quality of embryos in the presence and absence of ICA. Results: Treatment with 5 μM ICA (ICA-5) led to a significant reduction in ROS activity, but increased mRNA expression of glutathione and antioxidant genes (superoxide dismutase 1 [SOD1], SOD2, peroxiredoxin 5, and nuclear factor erythroid 2-like 2), during aging in vitro. In addition, ICA-5 prevented defects in spindle formation and chromosomal alignment, and increased mRNA expression of cytoplasmic maturation factor genes (bone morphogenetic protein 15, cyclin B1, MOS proto-oncogene, serine/threonine kinase, and growth differentiation factor-9). It also prevented apoptosis, increased mRNA expression of antiapoptotic genes (BCL2-like 1 and baculoviral IAP repeat-containing 5), and reduced mRNA expression of pro-apoptotic genes (BCL2 antagonist/killer 1 and activation of caspase-3). Although the maturation and cleavage rates were similar in all groups, the total cell number per blastocyst and the percentage of apoptotic cells at the blastocyst stage were higher and lower, respectively, in the control and ICA-5 groups than in the aging group. Conclusion: ICA protects oocytes against damage during aging in vitro; therefore, it can be used to improve assisted reproductive technologies.

• Korean Journal of Construction Engineering and Management
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• v.23 no.2
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• pp.33-44
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• 2022

The simulation function by the 4D system is a representative BIM function in the construction stage. For the 4D simulation, schedule information for each activity must be created and then linked with the 3D model. Since the 3D model created in the design stage does not consider schedule information, there are practical difficulties in the process of creating schedule information for application to the construction stage and linking the 3D model. In this study, after extracting the schedule information of the construction stage using the HDBSCAN algorithm from the 3D model in the design stage, authors propose a methodology for automatically generating schedule information by identifying precedence and sequencing relationships by applying the topological alignment algorithm. Since the generated schedule information is created based on the 3D model, it can be used as information that is automatically linked by the common parameters between the schedule and the 3D model in the 4D system, and the practical utility of the 4D system can be increased. The proposed methodology was applied to the four bridge projects to confirm the schedule information generation, and applied to the 4D system to confirm the simplification of the link process between schedule and 3D model.

• Journal of Korean Neurosurgical Society
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• v.65 no.4
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• pp.549-557
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• 2022

Objective : This study analyzed the risk factors in patients who developed distal junctional kyphosis (DJK) after posterior cervical fusion. Methods : We retrospectively analyzed the clinical and radiographic outcomes of 64 patients, aged ≥18 years (51 and 13 male and female patients, respectively), who underwent single-staged multilevel (3-6 levels) posterior cervical fusion surgery due to multiple cervical spondylotic myelopathy. The surgeries were performed by a single spinal surgeon between January 2012 and December 2017. Demographic data, clinical outcomes, and radiological results were collected. We divided the patients into a DJK group and a non-DJK group according to the presence of DJK and investigated the risk factors by comparing the differences between the two groups. Results : Of the 64 patients, 13 developed DJK. No significant differences in clinical results were observed between the two groups before and immediately after the surgery. At the final follow-up, a higher visual analog score for neck pain was observed in the DJK group compared to the non-DJK group (p<0.01). The DJK group had a significantly lower T1 slope and a significantly higher C2-7 sagittal vertical axis (SVA) before surgery compared to the non-DJK group (p=0.03 and p<0.01, respectively). Immediately after surgery, the difference between the two groups decreased and no significant difference was observed. However, at the last follow-up, a significantly higher C2-7 SVA was observed in the DJK group (p<0.01). At the last follow up, there is no discrepancy in T1S-CL. In multiple logistic regression analysis, preoperative higher C2-7 SVA and preoperative lower T1 slope were identified as independent risk factors (p=0.03 and p<0.01, respectively). As a result, it was confirmed that DJK occurred along the process of returning to preoperative values. Conclusion : DJK can be considered to be caused by cervical misalignment due to excessive change in the surgical site in patients with low T1 slope and high C2-7 SVA before surgery. This also affects the clinical outcome after surgery. It is recommended to refrain from excessive segmental lordosis changes during multilevel cervical post fusion surgery, especially in patients with a small preoperative T1 slope and a large SVA value.

• Journal of Advanced Navigation Technology
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• v.26 no.3
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• pp.160-165
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• 2022

In this paper, we have proposed a magnetic resonant 6.78MHz WPT(wireless power transfer) technique which can be applied to a fixed transmitter and a receiver of varying relative distance and coil alignment, Power transmission characteristics are studied with the relative distance and misalignment ration of coil area between the transmitting and receiving coils. The coils are designed with the size of 60×80mm² by direct feeding method, and the characteristics are derived with the maximum relative distance of 50mm and horizontal area misalignment state of 0-40mm misalignment of coil center axis in the XY plane. The power transmission characteristics are compared between the 3D EM simulation and the measured data, and the power transmission shows larger than -3dB performance with the vertical distance of up to 30mm and 50% area misalignmment ratio. This work showsthe transmission characteristics according to relative distance and misalignment state between the cols and that direct feeding has advantage for the short relative distance and small misalignment ratio.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.20 no.6
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• pp.84-99
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• 2021

As the micro-mobility market grows, the demand for route guidance, that includes uphill information as well, is increasing. Since the climbing angle depends on the electric motor uesed, it is necessary to establish an uphill road DB according to the threshold standard. Although road alignment information is a very important element in the basic information of the roads, there is no information currently on the longitudinal slope in the road digital map. The High Definition(HD) map which is being built as a preparation for the era of autonomous vehicles has the altitude value, unlike the existing standard node link system. However, the HD map is very insufficient because it has the altitude value only for some sections of the road network. This paper, hence, intends to propose a method to generate the road longitudinal slope using currently available data. We developed a method of computing the longitudinal slope by combining the digital elevation model and the standard link system. After creating an altitude at the road link point divided by 4m based on the Seoul road network, we calculated individual slope per unit distance of the road. After designating a representative slope for each road link, we have extracted the very steep road that cannot be climbed with personal mobility and the slippery roads that cannot be used during heavy snowfall. We additionally described errors in the altitude values due to surrounding terrain and the issues related to the slope calculation method. In the future, we expect that the road longitudinal slope information will be used as basic data that can be used for various convergence analyses.

• Journal of Plant Biotechnology
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• v.49 no.1
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• pp.30-38
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• 2022

Solanum brevicaule is one of the tuber-bearing wild Solanum species. Because of its resistance to several important pathogens infecting potatoes during cultivation, it can be used for potato breeding. However, the fact that S. brevicaule used in this study has an EBN value of two causes the sexual reproduction barriers between the species and cultivated potatoes. In this study, specific markers for discriminating S. brevicaule from other Solanum species were developed on the basis of the results of sequence alignments with the whole chloroplast genomes of S. brevicaule and seven other Solanum species. The chloroplast genome of S. brevicaule was completed by next-generation sequencing technology described in other recent studies. The total sequence length of the chloroplast genome of S. brevicaule is 155,531 bp. Its structure and gene composition are similar to those of other Solanum species. Phylogenetic analysis revealed that S. brevicaule was closely grouped with other Solanum species. BLASTN search showed that its genome sequence had 99.99% and 99.89% identity with those of S. spegazzinii (MH021562) and S. kurtzianum (MH021495), respectively. Sequence alignment identified 27 SNPs that were specific to S. brevicaule. Thus, three PCR-based CAPS markers specific to S. brevicaule were developed on the basis of these SNPs. This study will facilitate in further studies on evolutionary and breeding aspects in Solanum species.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.40 no.1
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• pp.15-25
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• 2022

This study was conducted to provide useful basic data for restoration and maintenance of the Changdeokgung Palace(昌德宮)'s inner palace area in the future by exploring the background of terraced flower beds installed in the front space of Seunghwaru(承華樓) and grasping the reality before and after terraced flower beds were installed. The main results of this study can be summarized as follows. First, in the early 1900s, the front space of Seunghwaru formed a relatively higher terrain than the Nakseonjae(樂善齋) area. In addition, along the topography of high north and low south, a yard surrounded by Haenggak(行閣) and a rectangular open space connected to the West Haenggak of Nakseonjae were created. In particular, the rectangular open space was a staircase-type slope in which rectangular stone columns were arranged at regular intervals. Second, the terraced flower beds of Seunghwaru originated from the renovation of the new building of Nakseonjae West Hanggak, which was implemented in the late 1920s. This is because in order to secure enough available land for construction and auxiliary space during the renovation of the new building, the terraced flower beds for topographic treatment was created along the cutting area after cutting off the original topography of the front space of Seunghwaru. Third, after the construction of the terraced flower beds, many deformation occurred in the topographic features of the front space of Seunghwaru. The front yard of Seunghwaru was relatively higher than the Nakseonjae area, but most of them were cut off and disappeared as the terraced flower beds were created. The staircase-type also disappeared after the construction of the new building and terraced flower beds. The stylobate and front fence of Seunghwaru were newly built along the alignment of terraced flower beds and the unique style of narrow gate and auxiliary stairs were also relocated to the new fence.

• Journal of Veterinary Science
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• v.23 no.4
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• pp.55.1-55.12
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• 2022

Background: ASF was first reported in Kenya in 1910 in 1921. In China, ASF spread to 31 provinces including Henan and Jiangsu within six months after it was first reported on August 3, 2018. The epidemic almost affected the whole China, causing direct economic losses of tens of billions of yuan. Cause great loss to our pig industry. As ELISA is cheap and easy to operate, OIE regards it as the preferred serological method for ASF detection. P54 protein has good antigenicity and is an ideal antigen for detection. Objective: To identify a conservative site in the African swine fever virus (ASFV) p54 protein and perform a Cloth-enzyme-linked immunosorbent assay (ELISA) for detecting the ASFV antibody in order to reduce risks posed by using the live virus in diagnostic assays. Method: We used bioinformatics methods to predict the antigen epitope of the ASFV p54 protein in combination with the antigenic index and artificially synthesized the predicted antigen epitope peptides. Using ASFV-positive serum and specific monoclonal antibodies (mAbs), we performed indirect ELISA and blocking ELISA to verify the immunological properties of the predicted epitope polypeptide. Results: The results of our prediction revealed that the possible antigen epitope regions were A23-29, A36-45, A72-94, A114-120, A124-130, and A137-150. The indirect ELISA showed that the peptides A23-29, A36-45, A72-94, A114-120, and A137-150 have good antigenicity. Moreover, the A36-45 polypeptide can react specifically with the mAb secreted by hybridoma cells, and its binding site contains a minimum number of essential amino acids in the sequence 37DIQFINPY44. Conclusions: Our study confirmed a conservative antigenic site in the ASFV p54 protein and its amino acid sequence. A competitive ELISA method for detecting ASFV antibodies was established based on recombinant p54 and matching mAb. Moreover, testing the protein sequence alignment verified that the method can theoretically detect antibodies produced by pigs affected by nearly all ASFVs worldwide.