• Journal of the Korea Concrete Institute
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• v.18 no.3 s.93
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• pp.397-404
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• 2006

This paper investigates experimentally the effect of combined addition of expansive additive and shrinkage reducing agent(SRA) on setting time, compressive strength and drying shrinkage of concrete. An increase of EA and SRA content leads to a reduction in flowability, which causes the increase of superplasticizer dosage, while air content increases. For setting time, in spite of increased superplasticizer dosage, with the increase of EA and SRA, setting time shortens. This is due to the presence of alkali ion by SRA and the faster formation of ettringite. At dosage of 5.0% of EA, concrete has the highest compressive strength and above that dosage, compressive strength decreased. On the contrary, the increase of SRA dosage results in a decrease in compressive strength. Combined addition of EA of 5.0% and SRA of 1.0% shows a comparable strength with control concrete. For drying shrinkage, as expected, the increase of EA and SRA dosage leads to reduction of drying shrinkage markedly. Moreover, combined addition of EA and SRA has better drying shrinkage reduction effect than individual use of EA and SRA by as much as $5{\sim}16%$. Optimal combination of EA and SRA is fixed at 5.0% of EA and 0.5% of SRA based on the consideration of the effect of EA and SRA on fresh state, compressive strength and shrinkage of concrete.

• Journal of Nutrition and Health
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• v.49 no.4
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• pp.233-240
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• 2016

Purpose: Diabetic complications are a major concern to manage progression of diabetes. Production of advanced glycation end products (AGEs) due to high blood glucose is one of the mechanisms leading to diabetic complications. Multiple pharmacologic AGE inhibitory agents are currently under development, but clinical applications are still limited due to safety issues. Thus, it is necessary to identify a safe anti-glycation agent. It is known that burdock roots have antioxidant, anti-inflammatory, and anti-cancer activities. The objective of the present study was to investigate the inhibitory role of burdock roots on the formation of high glucose-induced glycation of bovine serum albumin (BSA). Methods: In this study, glycation of BSA by glucose, galactose, or fructose at $37^{\circ}C$ for 3 weeks was assessed based on levels of ${\alpha}$-dicarbonyl compounds (early-stage glycation products), fructosamine (intermediate products of glycation), and fluorescent AGEs (late-stage glycation products). In order to compare the inhibitory actions of burdock root extract in AGE formation, aminoguanidine (AG), a pharmacological AGE inhibitor, was used as a positive control. Results: BSA glycation by glucose, fructose, and galatose was dose- and time-dependently produced. Burdock root extract at a concentration of 4 mg/mL almost completely inhibited glucose-induced BSA glycation. The results demonstrate that burdock root extract inhibited AGE formation with an $IC_{50}$ value of 1.534 mg/mL, and inhibitory activity was found to be more effective than the standard anti-glycation agent aminoguanidine. This study identified a novel function of burdock root as a potential anti-glycation agent. Conclusion: Our findings suggest that burdock root could be beneficial for preventing diabetic complications.

• Journal of Environmental Health Sciences
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• v.39 no.4
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• pp.335-345
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• 2013

Objectives: As the suspicion was raised that 'Agent Orange' was reclaimed 30 years ago at Camp Carol, located in Waegwan, Gyeongsangbuk-do, the government conducted an investigation of the influence of environmental and health effects around Camp Carol through a public-private joint investigation team. As part of the investigation of population health effects, this study was carried out in order to observe changes and regional differences in diseases, particularly cancer, by year. Methods: We authors conducted an analysis of secondary health data, such as cancer registration data, mortality data, and health insurance data. We drew an age standardized incidence ratio (SIR), death rate (SDR), mortality ratio (SMR), and health care utilization rate using these data. Results: For gastric cancer in women, and other cancers in men, a significant increase in incidence was observed compared to the control area. For biliary tract cancer, gallbladder cancer, and thyroid cancer in women, and prostate cancer in men, a significant decrease in incidence was observed compared to the control area. In the national statistical analysis of data, such as health insurance data and mortality data, we did not observe a significant increase at the Waegwan region compared to other regions. Conclusions: We must consider the limitations of this study. Because thirty years have passed from the time of the estimated landfill of 'Agent Orange', recent national statistical data may not reflect the past real situation. Therefore, the monitoring of secondary data for health effects at the municipal level should be carried out continuously.

• Journal of Construction Engineering and Project Management
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• v.4 no.2
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• pp.31-40
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• 2014

The management of vehicular supply of "perishable" construction material, such as concrete mixes, faces a series of uncertainties such as weather, daily traffic patterns and accidents. Presented in this paper is a logistics control model for managing a hauling fleet with interrelated processes at both ends and queue capacities. Discrete event simulation is used to model the complex interactions of production units and the randomness of the real world. Two alternative strategies for ready mix concrete delivery, with and without an off-site waiting queue, are studied to compare supply performance. Secondly, the paper discusses the effect of an agent-based GPS tracking system providing real-time travel data that lessens the uncertainty of trucking time. The results show that the combination of GPS information with off-site queuing reduces productivity loss and process wastes of concrete placement as well as the idleness of supply trucks when crew or pump experience an unexpected stoppage.

• 한국균학회소식:학술대회논문집
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• 2015.05a
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• pp.42-42
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• 2015

Plasmodiophora brassicae, the causal agent of clubroot disease, does the most serious damage to the Brassica crops. The limited control approaches make that the identification of clubroot resistance (CR) is more important for developing CR cultivars of the Brassica crops. So far, 8 CR loci were mapped. However, the variation of P. brassicae leads to the rapid erosion of its resistance. To identify novel CR genes, we employed three mapping population, derived from crosses between Chinese cabbage and turnip inbred lines ($59-1{\times}ECD04$ and $BJN3-1{\times}Siloga$) or between Chinese cabbage inbred lines ($BJN3-1{\times}85-I-II$), to perform QTL analysis. Totally, 8 CR loci were indentified and showed race-specific resistance. Physical mapping of these 8 loci suggested that 4 were located previously mapped position, indicating they might be the same allele or different alleles of the same genes. Other 4 loci were found to be novel. Further, CR near isogenic line carrying each CR locus was developed based on the marker assisted selection. Verification of these CR loci was underway. Identification of these novel CR genes would facilitate to breed broad-spectrum and durable CR cultivars of B. rapa by pyramiding strategies.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2003.09a
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• pp.94-97
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• 2003

Various bioinformatics tools for biological data processing have been developed and most of them are available in public. Most bioinformatics works are carried out by a composite application of those tools. Several integration approaches have been proposed for easy use of the tools. This paper proposes a new multiagent system architecture to integrate bioinformatics tools in the perspective of workflow since the composite applications of tools can be regarded as workflows. For the easy integration, the proposed architecture employs wrapper agents for existing tools, uses XML-based messages in the inter-agent communication, and agents are supposed to extract necessary information from the received messages. This allows new tools to be easily added on the integration framework. The proposed method allows various control structures in workflow definition and provides the progress monitoring capability of the on-going workflows. We implemented a prototype system of the proposed architecture for annotating the genes of a bacterium called Sphingomonas Chungbukensis DJ77.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2005.11a
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• pp.335-338
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• 2005

로봇 에이전트는 변화하는 환경에서 센서정보를 바탕으로 적절한 행동을 선택하며 동작하는 것이 중요하다. 행동 선택 네트워크는 이러한 환경에서 변화하는 센서정보에 따라 실시간으로 행동을 선택할 수 있다는 점에서, 장시간에 걸친 최적화보다 단시간 내 개선된 효율성에 초점을 맞추어 사용되어 왔다. 하지만 행동 선택 네트워크는 초기 문제에 의존적으로 설계되어 변화하는 환경에 유연하게 대처하지 못한다는 맹점을 가지고 있다. 본 논문에서는 행동 선택 네트워크의 연결을 LCS를 기반으로 진화 학습시켰다. LCS는 유전자 알고리즘을 통해 만들어진 규칙들을 강화학습을 통해 평가하며, 이를 통해 변화하는 환경에 적합한 규칙을 생성한다. 제안하는 모델에서는 LCS의 규칙이 센서정보를 포함한다. 진화가 진행되는 도중 이 규칙들이 모든 센서 정보를 포함하지 못하기 때문에 현재의 센서 정보를 반영하지 못하는 경우가 발생할 수 있다. 본 논문에서는 이를 해결하기 위해 센서정보 별로 개체를 따로 유지하는 방법을 제안한다. 제안하는 방법의 검증을 위해 Webots 시뮬레이터에서 케페라 로봇을 이용해 실험을 하여, 변화하는 환경에서 로봇 에이전트가 학습을 통해 올바른 행동을 선택함을 보였고, 일반LCS를 사용한 것보다 조건별 개체 유지를 통해 더 나은 결과를 보이는 것 또한 확인하였다.

• Journal of Microbiology and Biotechnology
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• v.18 no.9
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• pp.1492-1495
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• 2008

Successful control of Xanthomonas oryzae pv. oryzicola, the causal agent of bacterial leaf streak, requires a specific and reliable diagnostic tool. A pathovar-specific PCR assay was developed for the rapid and accurate detection ofthe plant pathogenic bacterium Xanthomonas oryzae pv. oryzicola in diseased plant. Based on differences in a membrane fusion protein gene of Xanthomonas oryzae pv. oryzicola and other microorganisms, which was generated from NCBI (http://www.ncbi.nlm.nih.gov/) and CMR (http://cmr.tigr.org/) BLAST searches, one pair of pathovar-specific primers, XOCMF/XOCMR, was synthesized. Primers XOCMF and XOCMR from a membrane fusion protein gene were used to amplity a 488-bp DNA fragment. The PCR product was only produced from 4 isolates of Xanthomonas oryzae pv. oryzicola among 37 isolates of other pathovars and species of Xanthomonas, Pectobacterium, Pseudomonas, Burkholderia, Escherichia coli, and Fusarium oxysporum f.sp. dianthi. The results suggested that the assay detected the pathogen more rapidly and accurately than standard isolation methods.

• The Plant Pathology Journal
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• v.28 no.3
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• pp.290-294
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• 2012

The fungus Pyrenophora graminea is the causal agent of barley leaf stripe disease. Two leaf stripe isolates PgSy3 (exhibiting high virulence on the barley cultivar 'Arabi Abiad') and PgSy1 (exhibiting low virulence on Arabi Abiad), were mated and 63 progeny were isolated and phenotyped for the reaction on Arabi Abiad. The population segregated in a 1:1 ratio, 32 virulent to 31 avirulent (${\chi}^2$ = 0.05, P = 0.36), indicating single gene control of PgSy3 virulence on Arabi Abiad. Among 96 AFLP markers identified, three AFLP markers, E37M50-400, E35M59-100 and E38M47-800 were linked to the virulence locus VHv1 in isolate PgSy3. The results of this study indicate that (the three markers) are closely linked to VHv1 and are unique to isolates carrying the virulence locus. This work represents an initial step towards map-based cloning of VHv1 in P. graminea.

• Proceedings of the Korea Contents Association Conference
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• 2004.11a
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• pp.564-569
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• 2004

Most existing ontologies are suited for static knowledge, so they lack capability of representing procedural knowledge which is essential for an agent's action control or inference in the virtual world. Also they are not prepared to describe objects beyond their fixed ranges of domains as designed. In this paper we propose cyber-microcosm ontology (CMO) which augments procedural aspects and expressive power for multiple forms rather than fixed form as in conventional ontologies. The resulting ontology will provide an enhanced knowledge structure to capture procedural aspects of agents' actions and to facilitate their associated inferencing. The procedural aspects of the CMO are designed based on action frame formed according to diverse elements. They are elaborated in terms of various qualifiers and quantifiers to reflect statistical natures over time and instances.