• Fashion & Textile Research Journal
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• v.14 no.1
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• pp.83-89
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• 2012

Recent rapid development of computer, information communication and Web service technologies is exerting considerable effects on all industrial areas. As such digital technologies are also introduced to the clothing and fashion industry and create 'virtual garment environment' consisting of 3D virtual bodies, virtual garments and virtual try-on systems, consumers are now able to try virtual garments on their virtual body online. This study was conducted in order to analyze consumers' tendency of clothing purchase using 3D virtual simulation technology, which is increasing attention throughout the world, and to propose strategies on the development of virtual try-on technology for activating apparel online shopping. The subjects of this study were men and women aged 18 or older living in the North Carolina State, U.S., and a questionnaire survey was conducted with them on their tendency of apparel online shopping and their preference for real garments and virtual garments. According to the results of this study, consumers' awareness of apparel shopping using virtual try-on was still low. Moreover, in the results of surveying consumers' purchase preference for real garments and virtual garments, preference was highest for real garment (P), which was followed by virtual garments OA, OB and BB. Based on the results of this study, for the activation of apparel online shopping using virtual simulation technology, it is considered necessary to provide services implementing virtual try-on similar to consumers' actual try-on. This requires further active research and technology development on virtual try-on simulation using digital technologies.

• Journal of Technology Innovation
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• v.14 no.3
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• pp.209-235
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• 2006

Since the end of the cold war, technical tie-up between private corporations and an army in developed countries has increased a lot, and the trend is spreading through developing countries rapidly. To cope with the circumstance actively, the dual use technology program for both private corporations and an army was begun in Korea in 1998. With the program, overlapping investment was resolved and technology transfer was stimulated. And the standardization and information exchange saved considerable national budget and made possible economic profit. Yet, the combination project of 4 ministries and offices showed problems such as loose cooperation and, low industralization record. However, developed countries are out of the mere stage of dual technology development and turn into broad technical tie-up including future prediction, national competitiveness improvement, and the private company's leading participation and they are systemizing them very fast. Korea also set up the national defense reform plan with the blueprint of future military force improvement, budget increase for national defense research, and increased participation of private corporations, and created Defense Acquisition program Administration to support them. The innovation of national defense system brings forward the need to link the private and military innovation. Korea has pursued the fast growth through assimilation, absorption, and improvement of foreign technology. But now, Korea has to focus on self innovation, original technology, parts and material. As this applies to private companies and military equally, it is important to concentrate limited resources for the effective technology cooperation. Considering this, the strategies to activate the dual use technology are program concept and range extension, task-deduction way improvement and future-oriented common task deduction, and promotion system improvement.

• Biomolecules & Therapeutics
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• v.20 no.6
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• pp.499-505
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• 2012

Chemoprevention represents a strategy designed to protect cells or tissues against various carcinogens and carcinogenic metabolites derived from exogenous or endogenous sources. Recent studies indicate that plant-derived triterpenoids, like oleanolic acid, may exert cytoprotective functions via regulation of the activity of different transcription factors. The chemopreventive effects may be mediated through induction of the nuclear factor erythroid 2-related factor 2 (Nrf2) transcription factor. Activation of Nrf2 by triterpenoids induces the expression of phase 2 detoxifying and antioxidant enzymes such as NAD(P)H quinone oxidoreductase 1 (NQO1) and heme oxygenase-1 (HO-1) - proteins which can protect cells or tissues against various toxic metabolites. On the other hand, inhibition of other transcription factors, like NF-${\kappa}B$ leads to the decrease in the pro-inflammatory gene expression. Moreover, the modulation of microRNAs activity may constitute a new mechanism responsible for valuable effects of triterpenoids. Recently, based on the structure of naturally occurring triterpenoids and with involvement of bioinformatics and computational chemistry, many synthetic analogs with improved biological properties have been obtained. Data from in vitro and in vivo experiments strongly suggest synthetic derivatives as promising candidates in the chemopreventive and chemotherapeutic strategies.

• Journal of the Korean Society for Library and Information Science
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• v.45 no.2
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• pp.163-184
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• 2011

The aim of this study is providing basic data to design successful in-service training program for teacher librarians by analyzing their preference on subjects of customized intensive programs for indicators of teacher expertise development. According to the survey, teacher librarians seem to regard training subjects such as Reading Education and Information Literacy Instruction related educational information services as core jobs and prefer developing instructional contents and materials. Under the levels of school it seems that teacher librarians in the elementary school are interested in programs for library activation, management of volunteers, analyses of users' needs and curricula, evaluations of user instruction and information literacy instruction. Older teacher librarians favor an understanding of metadata, building and supporting information system and instruction. Therefore, training subjects for teacher librarians should be formed by linking strategies between school library instruction and subject curricula. And in terms of the method of training, case studies and practical training might be better than lectures based on the theory.

• Korean Journal of Social Welfare
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• v.62 no.1
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• pp.5-30
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• 2010

This paper offers an alternative approach to measure the welfare state change by using fuzzy-set methodology. The fuzzy-set method is particularly useful for assessing change across a limited number of cases, and that it can help to translate interval fuzzy membership scores into verbal qualifiers. Applying the measurement of welfare state change, four sets(accessibility, generosity, activation, state's care responsibility) in two dimensions(old and new social risks) have been identified, which reflect theoretical importance. The analysis sets out fuzzy membership scores for 12 OECD countries in the 16 possible welfare state ideal types. This paper found that each country has its own strategies to deal with the changes, however, the changes are not dramatic or a qualitative one. This does not mean that there are no changes, but that are no paradigm shifts or path breaking in the welfare state changes.

• Journal of Korean Society on Water Environment
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• v.24 no.1
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• pp.91-98
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• 2008

This work was performed to develop a model possible to predict the influent flow and influent components, which are one of main disturbances causing process problems at the operation of municipal wastewater treatment plant. In this study, artificial neural network (ANN) was used in order to develop a model that was able to predict the influent flow, $COD_{Mn}$, SS, TN 1 day-ahead, 2day-ahead and 3 day ahead. Multi-layer feed-forward back-propagation network was chosen as neural network type, and tanh-sigmoid function was used as activation function to transport signal at the neural network. And Levenberg-Marquart (LM) algorithm was used as learning algorithm to train neural network. Among 420 data sets except missing data, which were collected between 2005 and 2006 at field plant, 210 data sets were used for training, and other 210 data sets were used for validation. As result of it, ANN model for predicting the influent flow and components 1-3day ahead could be developed successfully. It is expected that this developed model can be practically used as follows: Detecting the fault related to effluent concentration that can be happened in the future by combining with other models to predict process performance in advance, and minimization of the process fault through the establishment of various control strategies based on the detection result.

• Molecules and Cells
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• v.39 no.3
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• pp.258-265
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• 2016

In metastatic breast cancer, the acquisition of malignant traits has been associated with the increased rate of cell growth and division, mobility, resistance to chemotherapy, and invasiveness. While screening for the key regulators of cancer metastasis, we observed that neurotrophin receptor TrkB is frequently overexpressed in breast cancer patients and breast cancer cell lines. Additionally, we demonstrate that TrkB expression and clinical breast tumor pathological phenotypes show significant correlation. Moreover, TrkB expression was significantly upregulated in basal-like, claudin-low, and metaplastic breast cancers from a published microarray database and in patients with triple-negative breast cancer, which is associated with a higher risk of invasive recurrence. Interestingly, we identified a new TrkB-regulated functional network that is important for the tumorigenicity and metastasis of breast cancer. We demonstrated that TrkB plays a key role in regulation of the tumor suppressors Runx3 and Keap1. A markedly increased expression of Runx3 and Keap1 was observed upon knockdown of TrkB, treatment with a TrkB inhibitor, and in TrkB kinase dead mutants. Additionally, the inhibition of PI3K/AKT activation significantly induced Runx3 and Keap1 expression. Furthermore, we showed that TrkB enhances metastatic potential and induces proliferation. These observations suggest that TrkB plays a key role in tumorigenicity and metastasis of breast cancer cells through suppression of Runx3 or Keap1 and that it is a promising target for future intervention strategies for preventing tumor metastasis and cancer chemoprevention.

• The Journal of the Korea Contents Association
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• v.20 no.1
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• pp.217-232
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• 2020

The purpose of this study is to organize prior research related to e-commerce activation factors available to stakeholders in the online distribution industry, and to conduct FGI with e-commerce experts to calculate the importance of each factor in order based on the 3 Level Service Model of Kwon Hyeog-in (2010), the key factors derived through the preceding study and the FGI were structured and the weighting of each factor was derived using AHP methodology. In the higher factors, the private sector (0.542) > communes (0.237) > public (0.2222) appeared to be important. Sub-factories included 'search service development' (0.0970)', 'recommendation service development (0.0805)', 'consumer needs analysis (0.0534)', 'consumer consumption pattern analysis (0.0505)' and 'other platform-linked service development (0.0450)', in the order of weighting down, indicating each of the factors within the top 15 priority. The results of this study will be utilized throughout the e-commerce industry as well as e-commerce enterprises, providing an academic foundation for the rapidly growing e-commerce ecosystem.

• The Journal of the Korea Contents Association
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• v.15 no.5
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• pp.414-425
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• 2015

Purpose: This study was conducted to explore the experience of smart-home healthcare among older adults who had participated in the smart-home technology development project. Methods: Data were collected by focus group interviews with 7 hypertension or diabetes participants(mean age 75 years). Qualitative contents analysis was used to analyze the verbal data. Results: The results were composed of 27 meanings units, 10 categories and 6 themes. The 6 themes are: 'improvement of health conditions through anytime anywhere self-monitoring', 'attractive experience to be counselling at home', 'frequent system and telecommunication problems', 'unfamiliar devices for elderly users', 'complementary strategies for activation', 'advancement of elderly-friendly devices and programs'. Conclusion: The smart-home healthcare system should be developed based on older adults' preferences. It is essential to make progress with professional resources and organizational supports in the future.

• International Journal of Oral Biology
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• v.35 no.4
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• pp.215-220
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• 2010

Angelica decursiva has been used in Korean traditional medicine as an antitussive, an analgesic, an antipyretic and a cough remedy. However, its anti-cancer properties have not yet been well defined. In our current study, we report the cytotoxic activity and the mechanism of cell death induced by ethanol extracts of Angelica decursiva (EEAD) against the human oral cancer cell line, KB. Treatment of KB cells with EEAD induced apoptotic cell death in both a dose- and time-dependent manner as determined by MTT assay and DNA fragmentation. However, no cytotoxic effects of EEAD against human normal oral keratinocytes (HNOK) were evident. By western blot analysis, we found that apoptosis in KB cells is associated with a decrease in procaspase-7 and -9. In addition, the activation of caspase-7 was detectable in living KB cells by fluorescence microscopy. These results suggest that EEAD exhibits anti-cancer activity in KB cells via apoptosis and thus has potential as an anticancer agent in future drug development strategies.