• 대한세포병리학회지
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• 제19권2호
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• pp.178-182
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• 2008

We report here a case of a gastrointestinal stromal tumor (GIST) in the stomach that was diagnosed by endoscopic ultrasound-guided fine needle aspiration cytology (EUS-FNA). A 67 year old male patient underwent regular check-ups for five years due to the presence of a submucosal tumor that was found in the fundus of the stomach incidentally. EUS-FNA was performed to evaluate the tumor, which had increased in size from 1 cm to 2.8cm. A cytologic smear revealed cohesive sheets or clusters of spindle cells with elongated nuclei. Immunohistochemical staining revealed a strong positive reaction for c-kit and CD34, without any reaction for smooth muscle actin and Ki-67. Therefore, a diagnosis of GIST was made.

• 동의생리병리학회지
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• 제20권6호
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• pp.1451-1458
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• 2006

Hae Ron(海論) was recorded to Tae So(太素)‘s volume 5 Sa-hae-hap(四海合), Gap Eul(甲乙)’s volume 1 chapter 8 Sahae(四海) and You Gyeong(類經)‘s volume 9 Gyung-lak-ryu-sam-sib-yi(經絡類三十二) Yin-ji-sa-hae(人之四海). Human body has the Sahae(四海; Gi hae, Heul hae, Sugok hae, Su hae) as like as Earth has Sahae(四海; East sea, West sea, South sea, North sea). Person's Sahae corresponds with Earth's Sahae. This chapter is explaining about Acupoint's position that Sahae's Gi-hyeol 氣血) comes in and go out, symptoms of disease, that can appear When Sahae lost homeostasis and the treatment principle, Yeong-wi-gi-hyeo(營衛氣血) enables complex vital phenomenon of human body. This Yeong-wi-gi-hyeo(營衛氣血) can not move if there is no systematic O-jang yuk-bu(五臟六腑), Sip-yi-gyeong-maek (十二經脈)) and Gi-gyeong-pal-maek (奇經八脈). For these system batch, it is Sahae do most important part. Sahae is synthetic and systematic concept. This chapter is explaining the position and function. Together, This chapter is presenting symptoms and treatment principle that can appear when Sahae overbalanced. This is offering important clue in Korean medicine physiology and pathology phenomeno study. Therefore, I gathers and compares and analyzed commentese of several doctors to grasp difinitely this chapter's contents, and also investigated and translated.

• Food Science and Biotechnology
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• 제27권6호
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• pp.1823-1831
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• 2018

This study examined the efficacy of Atractylodes macrocephala Koidz (AMK) protein and polysaccharide extracts as adjuvant or adjuvant booster when given together with porcine pleuropneumonia vaccine. Experimental mice (n = 5/group) were subcutaneously immunized with $25{\mu}g$ ApxIIA #3 antigen, a target protein against A. pleuropneumoniae, together with alum and/or various concentrations ($0-500{\mu}g$) of the AMK extracts, while the control group received PBS only. Immunization with ApxIIA #3 antigen increased the antigen-specific IgG titer and this increase was enhanced in the immunization together with AMK protein, but not polysaccharide extract. Supplementation of AMK protein extract exhibited dose-dependent increases in the antigen-induced protective immunity against A. pleuropneumoniae challenge and in the lymphocyte proliferation specific to the antigen. Glycoproteins present in the AMK extract were the active components responsible for immune response induction. Collectively, the present findings suggest that AMK glycoproteins are useful as immune stimulating adjuvant or adjuvant booster.

• 한국산학기술학회논문지
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• 제20권2호
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• pp.543-551
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• 2019

본 연구의 목적은 중년남성의 자살생각에 영향을 미치는 스트레스, 사회적지지, 우울, 음주 간의 인과관계를 알아보고자 시도하였다. 연구대상자는 만44-64세 중년남성 236명을 대상으로 자가 보고형 설문지를 이용하였으며, 2018년 4월 11일 부터 6월 01일까지 자료 수집하였다. 수집된 자료는 PASW 21.0과 AMOS 18.0 programs을 이용하여 경로분석을 실시하였으며, 최종 모형의 적합지수는 RMSEA .05, GFI .99, AGFI .95, NFI .98로 나타났다. 연구결과는 다음과 같다. 첫째, 중년남성의 스트레스는 우울, 음주에 직접효과가 있었고, 사회적 지지는 우울에 직접효과가 나타났다. 둘째, 중년남성의 스트레스와 사회적 지지는 자살생각에 직접효과가 나타났으며, 스트레스와 사회적 지지는 자살생각에 간접효과가 나타났다. 따라서 중년 남성의 스트레스와 사회적 지지는 자살생각관계에서 우울의 부분매개효과가 확인되었다. 이러한 결과를 바탕으로 중년남성의 자살생각에 미치는 영향요인을 기초하여 자살생각을 감소할 수 있는 프로그램 개발 및 적용하는 것이 필요하다. 또한 본 연구의 결과가 자살생각의 기초자료로 활용되기를 기대한다.

• 한국임상보건과학회지
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• 제7권1호
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• pp.1248-1256
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• 2019

Purpose: The purpose of this study was to identify the effects of the gender role conflict on nursing professionalism in male nursing college students. Method: The subjects were 113 male college students in D and J city. The data were collected from April 24 to May 3, in 2017 using a structured questionnaire. The data were analyzed using the SPSS WIN 24.0 program. For data analysis, independent t-test, One-way ANOVA, Pearson's correlation coefficient and multiple linear regression analysis were carried out. Results: The results are follows. First, the individual characteristics in gender role conflict were significantly different in motivation(F=2.62, p=0.028) and the entering college decision(F=3.14, p=0.028), and nursing professionalism were significantly different in the entering college decision(F=4.34, p=0.006). Second, a negative relationship was observed between the gender role conflict and nursing professionalism(r=-.287, p=<0.01). The success, power and competition(${\beta}=0.19$, p<0.05) and male superiority(${\beta}=-0.47$, p<0.001) were found to influence nursing professionalism. Conclusion: These results highlight the need to develop educational intervention to lower the superiority of the male and to encourager success, power and competition of male nursing college students.

• BMB Reports
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• 제55권6호
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• pp.281-286
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• 2022

Hepatocellular carcinoma is a major health burden, and though various treatments through much research are available, difficulties in early diagnosis and drug resistance to chemotherapy-based treatments render several ineffective. Cancer stem cell model has been used to explain formation of heterogeneous cell population within tumor mass, which is one of the underlying causes of high recurrence rate and acquired chemoresistance, highlighting the importance of CSC identification and understanding the molecular mechanisms of CSC drivers. Extracellular CSC-markers such as CD133, CD90 and EpCAM have been used successfully in CSC isolation, but studies have indicated that increasingly complex combinations are required for accurate identification. Pseudogene-derived long non-coding RNAs are useful candidates as intracellular CSC markers - factors that regulate pluripotency and self-renewal - given their cancer-specific expression and versatile regulation across several levels. Here, we present the use of microarray data to identify stemness-associated factors in liver cancer, and selection of sole pseudogene-derived lncRNA ZNF204P for experimental validation. ZNF204P knockdown impairs cell proliferation and migration/invasion. As the cytosolic ZNF204P shares miRNA binding sites with OCT4 and SOX2, well-known drivers of pluripotency and self-renewal, we propose that ZNF204P promotes tumorigenesis through the miRNA-145-5p/OCT4, SOX2 axis.

• 한국식품영양학회지
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• 제36권6호
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• pp.572-580
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• 2023

Hypertension is characterized by excessive renin-angiotensin system activity, leading to blood vessel constriction. Several synthetic compounds have been developed to inhibit renin and angiotensin-converting enzyme (ACE). These drugs often have adverse side effects, driving the exploration of plant protein-derived peptides as alternative or supplementary treatments. This study assessed the phenolic compound and amino acid content and the antioxidant and antihypertensive activity of 5 South Korean staple crops. Sorghum had the highest phenolic compound content and exhibited the highest antioxidant activity. Millet grains, particularly finger millet (38.86%), showed higher antihypertensive activity than red beans (14.42%) and sorghum (17.16%). Finger millet was found to contain a large proportion of branched-chain, aromatic, and sulfur-containing amino acids, which are associated with ACE inhibition. In particular, cysteine content was positively correlated with ACE inhibition in the crops tested (r=0.696, p<0.01). This study confirmed that the amino acid composition was more correlated with the antihypertensive activity of grains than the phenolic compound content. Finger millet mainly contained amino acids, which have higher ACE inhibitory activity, resulting in the strongest antihypertensive activity. These findings underscore the antihypertensive potential of select crops as plant-based food ingredients, offering insight into their biological functions.

• 동국한의학연구소논문집
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• 제2권1호
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• pp.73-105
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• 1993

To say nothing of the orient and the west, the human beings discover the method of Jin Mac(診脈) by the way that observe disease. But oriental medicine devise special method of Jin Mac(診脈) in the study of Kyoung Mac(經脈). Although sip-ei Kyoung Mac Jin(十二經脈診), Sam Bu Gu Who Jin(三部九候診), In Young Mac Gu Jin(人迎脈口診), Chon Kwan Chuck Jin(寸關尺診) namely Yuk Bu Jung Wee Jin Mac (六部定位診脈) that is used today are devised, it has changed naturally by the changing treatment and the introduction of Yuin Yang(陰陽) and five element(五行). Many methods dg Jin Mac(診脈), it had not developped successing alternative, it had developped of declined by it's own way. 1. Results for the birth of Mac(脈) 1) Mac(脈), it means Kyoung Mac(經脈), at first entirelly Mac(脈), is seized a blood vessel that flows in the body. As presumed today, after finding many acupunture point, a general idea of Mac(脈) is not maked by the line that connect point and point, it connect between acupunture point and acupunture point. 2) Like blood flows in Hyul Mac(血脈), Gie(氣) flows in Kyoung Mac(經脈). The two things relate deeply each other. In a general idea or actrally Kyoung Rak(經洛), the two things sometimes accord, sometimes seperate, sometimes mix alternative. 3) Hyul Mac(血脈) and Kyoung Mac(經脈), we call it Mac(脈) entirely Kyoung Mac(經脈), is a way that manifest disease through Kyoung Mac(經脈) or a boundary that disease belongs to it method of Mac Jin(脈診) individual that disease of Kyoung Mac(經脈) is diagnosed by the jumping situation of Hyul Mac(血脈). 4) In method of Moxa, athough the pathology and the diagnostic of Mac(脈) are created by finding Mac(脈). Finding acupunture have opportunitty fot Mac Jin(脈診) and treatment. 2. Results of Kyoung Mac Mac Jin(經脈脈診) 1) In theory of kyoung Rak(經洛), disease are resumed for malfunction of Young Wee(榮衛) that flows in Kyung Rak(經洛). So to speak, in treatment of Kyoung Rak area, the purpose of diagnosis observe the situation of disease and cause. For fitting the purpose of diagnosis, the dead had esatablised four-diagnosis method mangMunMnnJeul(望聞問切), in four-diagnosis(四診法), the core is Mac Jin(脈診). 2) sip-ei Kyoung Mac Mac Jin(十二經脈診) had existed as Kyoung Mac Mac Jin(經脈脈診), it precedes Sam Bu Gu Who Jin(三部九候診). In Young Ki Gu Mac(人迎脈口診). 3) Although Bu Yang Mac(趺陽脈), So Um Mac(少陰脈) is a part of Sip-ei Kyoung Mac(十二經脈診), they developped especially because they located in the point of Won Hyul(原穴) and they are convenient for diagnose. 4) Sip-ei Kyoung Mac Mac Jin(十二經脈診), which belongs to Bu Yang Mac(趺陽脈) and So Urn Mac(少陰脈), is not important for the comming age medical books compared with Mac Kyoung(脈經). 3. Results gor Sam Bu Gu Who Jin(三部九候診) 1) Mac Jin(脈診) of Sam Bu Gu Who(三部九候), which is noted in the theory of Sam Bu Gu Who(三部九候診) of So Mun(素問), belongs to Kyoung Mac Mac Jin's(經脈脈診) geneology, Sip-ei Kyoung Mac Mac Jin(十二經脈診) is arranged, simplicated by the idealogy three talents(三才思想) in the heaven and the earth. 2) What Sam Bu Gu Jin(三部九候診) is regardded as very important in So Mun(素問), the editor of So Mun(素問) recognize the meaning that one discover disease early in this method of diagnosis. 3) After Young chu(靈樞), Nan Kyoung(難經) it is lacked the method of Sam Bu Gu Who Jin(三部九候診) in the books that treatment has changed. Sam Bu Gu Who Jin(三部九候診) based on actually clinic appropriate. 4. results for In Young Mac Gu Jin(人迎脈口診) 1) In Young Mac Gu Jin(人迎脈口診) is the method of comparative Mac Jin(脈診) according to the theory of Yin Yang(陰陽), it is presumed after Sam Bu Gu Who Jin(三部九候診), it had perished in parallel with the development of the theory of five elelment(五行). The development of the acupunture, the perishment of the treatment of negative(刺絡). 2) In Young Mac Gu Jin(人迎脈口診), Wang Suk Wha(王叔和) recreated that the left is In Young(人迎), the right is Kie Gu(氣口). In future generations by Jin Mu Taek(陳無擇) who is the writer of Sam In Bang(三因方). In Young Mac Gu Jin(人迎脈口診) is a measure for disease which classify it's inside and outside cause. 5. Results for Chon Gu Mac Jin(寸口脈診) 1) What we say Mac Jin(脈診) of Chon Gu(寸口) two means are used in commn. First case, we simply say the area of Chon Gu(寸口), second case, we say Chon Kwan Chuk Jin(寸口尺診) reducingly. Chon Gu(寸口) is the area which is the radial artery of wrist joint. What we attemp diagnose by only Chon Gu Mac(寸口脈), it is clearly shoued in the method of Nan Kyoung, five Nan(難經五難). 2) Because Jin Mac(診脈) is made in only Chon Gu(寸口), that is the area in which is concentated Kyoung Kee(經氣). That is the birth of Jin Kee(眞氣) and Jin Kee(眞氣) is related with disease. We can diagnose disease by taking Chon Gu(寸口). 3) Chuk Jin(尺診) in Nae Kyoung(難經) have two things. One is Il Chuk(一尺), the other is Chon Kwan Chu(寸關尺). 4) Chuk Chon Jin(尺寸診) is the method which diagnose the difference of point and the condition of Mac(脈) by dividing a part of Chuk(尺) in the area of Chon Gu(寸口). In Chon Gu Jin(寸口診), by introducing the theory of Yin Yang(陰陽), the method of Chon Gu Jin(寸口診) is developed by chon Gu Jin(寸口診). 5) What Chuk Kwan Chon Jin(寸關尺診) is that area of the Chon Gu(寸口) are divided fot three point, we can diagnose. By consulting Sam Bu Gu Who Jin(三部九候診), developping of the method of acupunture, utilzing the theory of five element(五行) it is devised by concentrating way of thinking of the method mac Jin(脈診) exiting. 6) Chon Kwan Chuk Jin MaC(寸關尺診脈) begin from Nae Kyoung(內徑) exiting. After Nan Kyoung(內徑), spread out widely from Mac Kyoung(脈診) of Wang Suk wha(王叔和), the future medicins followed it. Yang Hyun Jo(楊玄操) and established Chon Kwan Chuk Jin(寸關尺診) which is used widely today. This right and left Chon Kwan Chuk Jin(寸關尺診), we call it method of Yuk Bu Jung Wee Jin Mac(六部定位診脈). 7) We can think the base which presume the arrangement of the viscera for Chon Kwan Chuk(寸關尺) of the right and the left. 8) The origin, which seperate the right and the left of Mac(脈), is showed at the treory of Ji Jin Yo Dae(至眞要大論) in So Mun(素問) which Chon Chuk(寸尺) seperate the right and the left. But the method of diagnosis in Nan Kyoung(難經) have no seperation the fight and the left. Otherwise this. there is clearly writtened the seperation for the right origin of the method of Yuk Bu Jung Wee Jin Mac(六部定位診脈) seek for Cang Gong(倉公). 9) Yang Hyun Jo(楊玄操) notice that the Chuk(尺) is mentioned for Sam Cho(三焦) in the method of Mac Kyuong(脈經), Sim Po Kyung(心包經) which put together with Sam Cho(三焦) allot on this, he had established the method of Yuk Bu Jung Wee Jin Mac(六部定位診脈). 10) On the method of Paen Jak Yin Yang Mac(扁鵲陰陽脈) in Mac Kyoung(脈經), equal article exist with the theory of Pyung In Kee Sang(平人氣象論) in So Mun(素問). When Wang Suk Wha(王叔和) write Mac Kyung(脈經), we can presume that the book of Mac(脈) which Paen Jak(扁鵲) had experienced the origin have exited besides So Mun(素問), Young Chu(靈樞). If so he must be make Chon Kwan Chuk Jin(寸關尺診) very fairly standard. So Nae Kyoung(內經), which must be fllowed the method of Paen Jak Mac(扁鵲脈), do the method diagnosis of Chon Kwan Chuk(寸關尺), diagnise of disease and treat.

• 영재교육연구
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• 제23권3호
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• pp.479-499
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• 2013

본 연구는 어머니의 양육태도가 유아의 지능과 다중지능 및 정서지능 간의 관계와 그 상대적 영향력을 분석하는 데 목적을 두었다. 이를 위해 만 3~5세 유아 215명과 그들의 어머니와 담임교사 15명을 대상으로 양육태도, 지능, 다중지능과 정서지능 검사를 실시하였다. 자료처리는 단순적률상관분석을 이용하여 각 변인간의 상관계수를 산출하였으며, 후진(backward)방법을 활용한 중다회귀분석을 실시하였다. 본 연구에서의 결론은 다음과 같다. 첫째, 어머니의 양육태도와 지능, 다중지능 간의 관계는 상관이 낮은 것으로 나타난 반면에 정서지능과의 관계는 상관이 높은 것으로 나타났다. 둘째, 거부적 태도와 자율적 태도가 유아의 지능 전체를, 거부적 태도가 다중지능 전체를, 애정적 태도와 자율적 태도가 정서지능 전체를 가장 잘 설명해 주는 변인으로 나타났다. 이러한 결과는 지능, 다중지능, 정서지능의 발달에 있어 어머니의 양육태도는 획일적으로 특정 태도를 보여주기보다는 자율적 태도를 중심으로 상황에 따라 애정적 태도를 보여주고 거부적 태도는 피하는 것이 바람직하다는 것을 시사한다.

• Carbon letters
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• 제1권2호
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• pp.53-59
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• 2000

The synthetic methods for high yield of multiwalled carbon nanotube (MWNT) and singlewalled carbon nanotube (SWNT) with high purity by arc discharge have been investigated. MWNTs were synthesized under different pressures of helium and the gas mixture of argon and hydrogen. Relatively high pressure of 300-400 torr was required for high yield MWNTs synthesis at low bias voltage of about 20 V and 55 A, whereas low pressure of about 100 torr was required for SWNTs. The introduction of hydrogen gases during the synthesis of MWNTs improved the yield and purity of the samples. The SWNTs were synthesized by the assistance of a small amount of mixture of transition metals, which played as a catalyst during the formation process. The purity and yield of SWNTs were higher at a lower pressure and enhanced by mixing more components of the transition metals.