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검색결과 301건 처리시간 0.025초

A High-Lateral Resolution MALDI Microprobe Imaging Mass Spectrometer Utilizing an Aspherical Singlet Lens

  • Han, Sang Yun;Kim, Hwan Jin;Ha, Tae Kyung
    • Bulletin of the Korean Chemical Society
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    • 제34권1호
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    • pp.207-210
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    • 2013
  • We report the construction of a MALDI imaging mass spectrometer equipped with a specially designed laser focusing lens, a compact aspherical singlet lens, that obtains a high-lateral imaging resolution in the microprobe mode. The lens is specially designed to focus the ionization laser (${\lambda}$ = 355 nm) down to a $1{\mu}m$ diameter with a long working distance of 34.5 mm. With the lens being perpendicular to the sample surface and sharing the optical axis with the ion path, the imaging mass spectrometer achieved an imaging resolution of as good as $5{\mu}m$ along with a high detection sensitivity of 100 fmol for peptides. The mass resolution was about 900 (m/${\Delta}m$) in the linear TOF mode. The high-resolution capability of this instrument will provide a new research opportunity for label-free imaging studies of various samples including tissues and biochips, even for the study at a single cell level in the future.

밸브 없는 양방향 피에조 마이크로펌프의 유동해석 (A Numerical Study on Flow Analysis of a Valveless Bidirectional Piezoelectric Micropump)

  • 이상혁;허인영;허남건
    • 한국유체기계학회 논문집
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    • 제11권3호
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    • pp.14-21
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    • 2008
  • A numerical simulation on the flow field of a valveless bidirectional piezoelectric micropump has been performed. In this type of micropump, the oscillation of the piezoelectric diaphragm generates the blowing and suction flow through the oblique channel from the pumping chamber. The angle between the oblique and main channel causes the variation of flow distribution through upstream and downstream channels in suction and blowing modes. In the suction flow mode, the working fluid flows from both the upstream and downstream of the main channel to the pumping chamber through the oblique channel. However, in the blowing flow mode, the fluid pushed out of the pumping chamber flows more toward the downstream of the main channel due to the inertia of the fluid. In the present study, the effects of geometries such as the angle of oblique channel and the shape of main channel on the flow rate of the up/downstream were investigated. The flow rate obtained from the pump and the energy required to the pump were also analyzed for various displacements and frequencies of the oscillation of the diaphragm.

전력용 능동필터형 무정전 전원장치 (Active Power Filter Type Uninterruptible Power Supply (UPS))

  • 김제홍;최재호
    • 조명전기설비학회논문지
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    • 제12권4호
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    • pp.100-105
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    • 1998
  • 본 논문은 고조파와 무효전력을 보상하는 전력용 능동펼터의 성능을 가지는 무정전 전원장치의 제어기볍올 제안 한다. 제안된 시스템은 단지 하나의 전력변환회로만올 가지고 AC/DC 정류기 및 배터리 충전기 그리고 인버터로서 동작할 수 있다. 더욱이 상용전원이 정상일 경우 제안된 시스템은 비선형 부하에 의해 발생된 고조파 및 무효 전 력올 보상하기 위해 전력용 능동필터 모드로 동작한다. 그리고 상용전원이 비정상일 경우는 인버터로 동작하여 배터리에 충전된 전력을 부하로 공급하는 배터리 방전전력 모드로 동작올 한다. 전력용 능동필터 모드에서 보상전류 를 정확히 계산하기 위한 새로운 폐-루프 방식을 제안한다. 마지막으로 제안된 5[kVA]급 시스템의 성능이 시뮬레이션과 실험결과들에 의해 입증된다.

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무어링 윈치의 분할각도에 따른 강도해석 (The Strength Analysis of Mooring winch according to the division angle)

  • 하정민;한동섭;한근조
    • 한국항해항만학회:학술대회논문집
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    • 한국항해항만학회 2009년도 공동학술대회
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    • pp.181-182
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    • 2009
  • 기계장치에 있어서 브레이크 시스템은 기계의 동작에 못지않게 중요한 부분이다. 만약 기계가 멈추지 않으면 큰 사고의 발전할 수 있기 때문이다. 이것은 선박에서 또한 마찬가지이다. 선박에서 항해중 배를 정지시키기 위해서는 윈드라스 윈치를, 배를 항구에 계류시키기 위해서 무어링 윈치를 사용한다. 본 연구에서는 배를 항구에 계류시키는 무어링 윈치의 제동력을 향상시키기 위해 브레이크 밴드를 분리하였고, 이 분리한 무어링 윈치에서 가장 적절한 분리지점을 찾는 연구를 하였다.

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머신러닝을 이용한 스타트 모터의 고장예지 (Failure Prognostics of Start Motor Based on Machine Learning)

  • 고도현;최욱현;최성대;허장욱
    • 한국기계가공학회지
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    • 제20권12호
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    • pp.85-91
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    • 2021
  • In our daily life, artificial intelligence performs simple and complicated tasks like us, including operating mobile phones and working at homes and workplaces. Artificial intelligence is used in industrial technology for diagnosing various types of equipment using the machine learning technology. This study presents a fault mode effect analysis (FMEA) of start motors using machine learning and big data. Through multiple data collection, we observed that the primary failure of the start motor was caused by the melting of the magnetic switch inside the start motor causing it to fail. Long-short-term memory (LSTM) was used to diagnose the condition of the magnetic locations, and synthetic data were generated using the synthetic minority oversampling technique (SMOTE). This technique has the advantage of increasing the data accuracy. LSTM can also predict a start motor failure.

Vibration modelling and structural modification of combine harvester thresher using operational modal analysis and finite element method

  • Zare, Hamed Ghafarzadeh;Maleki, Ali;Rahaghi, Mohsen Irani;Lashgari, Majid
    • Structural Monitoring and Maintenance
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    • 제6권1호
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    • pp.33-46
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    • 2019
  • In present study, Operational Modal Analysis (OMA) was employed to carry out the dynamic and vibration analysis of the threshing unit of the combine harvester thresher as a mechanical component. The main study is to find the causes of vibration and to decrease it to enhance the lifetime and efficiency of the threshing unit. By utilizing OMA, structural modal parameters such as mode shapes, natural frequencies, and damping ratio was calculated. The combine harvester was excited by engine to vibrate different parts and accelerometer sensor collected acceleration signals at different speeds, and OMA was utilized by nonparametric and frequency analysis methods to obtain modal parameters while vibrating in real working conditions. Afterwards, finite element model was designed from the thresher and updated using the data obtained from the modal analysis. Using the conducted analyses, it was specified that proximity of the thresher pass frequency to one of the natural frequencies (16.64 Hz) was the most important effect of vibration in the thresher. Modification process of the structure was carried out by increasing mass required for changing the natural frequency location of the first mode to 12.4 Hz in order to reduce resonance and vibration of the thresher.

Behaviors of novel sandwich composite beams with normal weight concrete

  • Yan, Jia-Bao;Dong, Xin;Wang, Tao
    • Steel and Composite Structures
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    • 제38권5호
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    • pp.599-615
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    • 2021
  • The ultimate strength behaviour of sandwich composite beams with J-hooks and normal weight concrete (SCSSBJNs) are studied through two-point loading tests on ten full-scale SCSSBJNs. The test results show that the SCSSBJN with different parameters under two-point loads exhibits three types of failure modes, i.e., flexure, shear, and combined shear and flexure mode. SCSSBJN failed in different failure modes exhibits different load-deflection behaviours, and the main difference of these three types of behaviours exist in their last working stages. The influences of thickness of steel faceplate, shear span ratio, concrete core strength, and spacing of J-hooks on structural behaviours of SCSSBJN are discussed and analysed. These test results show that the failure mode of SCSSBJN was sensitive to the thickness of steel faceplate, shear span ratio, and concrete core strength. Theoretical models are developed to estimate the cracking, yielding, and ultimate bending resistance of SCSSBJN as well as its transverse cross-sectional shear resistance. The validations of predictions by these theoretical models proved that they are capable of estimating strengths of novel SCSSBJNs.

Simulation study of magnetorheological testing cell design by incorporating all basic operating modes

  • Mughni, Mohd J.;Mazlan, Saiful A.;Zamzuri, Hairi;Yazid, Izyan I.M.;Rahman, Mohd A.A.
    • Smart Structures and Systems
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    • 제14권5호
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    • pp.901-916
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    • 2014
  • Magnetorheological (MR) fluid is one of the field-responsive fluids that is of interest to many researchers due to its high yield stress value, which depends on the magnetic field strength. Similar to electrorheological (ER) fluid, the combination of working modes is one of the techniques to increase the performance of the fluids with limited focus on MR fluids. In this paper, a novel MR testing cell incorporated with valve, shear and squeeze operational modes is designed and constructed in order to investigate the behaviour of MR fluid in combined mode. The magnetic field distribution in the design concept was analyzed using finite element method in order to verify the effective areas of each mode have the acceptable range of flux density. The annular gap of valve and shear were fixed at 1 mm, while the squeeze gap between the parallel circular surfaces was varied up to 20 mm. Three different coil configurations, which were made up from 23 SWG copper wires were set up in the MR cell. The simulation results indicated that the magnetic field distributed in the squeeze gap was the highest among the other gaps with all coils were subjected to a constant applied current of 1 A. Moreover, the magnetic flux densities in all gaps were in a good range of magnitude based on the simulations that validated the proposed design concept. Hence, the 3D model of the MR testing cell was designed using Solidworks for manufacturing processes.

다른 형태를 가진 2소자 프린트 안테나의 방사특성에 관한 연구 (A Study of the Radiation Characteristics of Novel Printed Antenna Composed of Dual Elements with Different Shape)

  • 이채봉;김정현
    • 융합신호처리학회논문지
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    • 제9권2호
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    • pp.141-145
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    • 2008
  • 길이가 서로 다른 평행선로에 전류가 흐르는 경우, 커먼모드 전류(Common mode current)에 의한 전자파의 방사가 일어난다. 이러한 방사 원리를 이용하여 경량, 소형의 길이가 다른 2소자 선형 안테나가 제안되어 있다. 그러나 이 안테나의 경우 선으로 결합된 구조를 가지기 때문에 제작에 있어서 많은 제약이 따른다. 본 논문에서는 선형 안테나의 단점을 개선하고, 제작과 설계가 용이한 평면 기판에 길이가 다른 2소자 평면 안테나를 설계하고, 광대역(UWB: Ultra Wide Band)의 특성을 가지는 안테나를 설계하였다. 그리고 안테나 소자에 삼각형 패치 S, 노치, 테이퍼를 설계함으로서 방사특성은 다이 폴 안테나와 비슷하나 보다 넓은 대역에서 동작하는 안테나를 제작 할 수 있었다. 그 결과 비대역($VSWR{\le}2$)이 약 58%가 되었다.

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저 전력 시스템을 위한 파워다운 구조를 가지는 이중 전하 펌프 PLL 기반 클록 발생기 (A Dual Charge Pump PLL-based Clock Generator with Power Down Schemes for Low Power Systems)

  • 하종찬;황태진;위재경
    • 대한전자공학회논문지SD
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    • 제42권11호
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    • pp.9-16
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    • 2005
  • 이 논문에서는 다중 동작 주파수를 갖는 고성능 저전력 SoC에 사용 가능한 광대역 입출력 주파수를 지원하는 프로그램머블 PLL 기반의 클록킹 회로을 제안하였다. 제안된 클록 시스템은 이중 전하펌프를 이용 locking 시간을 감소시켰고, 광대역 주파영역에서 동작이 가능하도록 하였다. 칩의 저 전력 동작을 위해 동작 대기모드 시에 불필요한 PLL 회로를 지속적으로 동작시키지 않고 relocking 정보를 DAC를 통해 보존하고 불필요한 동작을 억제하였고, 대기모드에서 빠져나온 후 tracking ADC(Analog to Digital Converter)를 이용하여 빠른 relocking이 가능하도록 설계하였다. 또한 프로그램머블하게 출력 주파수를 선택하게 하는 구조를 선택하여 저 전력으로 최적화된 동작 주파수를 지원하기 위한 DFS(Dynamic frequency scaling) 동작이 가능하도록 클록 시스템을 설계하였다. 제안된 PLL 기반의 클록 시스템은 $0.35{\mu}m$ CMOS 공정으로 구현하였으며 2.3V의 공급전압에서 $0.85{\mu}sec\~1.3{\mu}sec$($24\~26$사이클)의 relocking 시간을 가지며, 파워다운 모드 적용 시 PLL의 파워소모는 라킹 모드에 비해 $95\%$이상 절감된다. 또한 제안된 PLL은 프로그래머블 주파수 분주기를 이용하여 다중 IP 시스템에서의 다양한 클록 도메인을 위해 $81MHz\~556MHz$의 넓은 동작 주파수를 갖는다.