• 한국식품영양학회지
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• 제26권3호
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• pp.485-491
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• 2013

본 연구에서는 피로 회복 또는 원기 회복에 효능이 있는 것으로 알려진 홍경천과 홍삼을 이용하여 홍경천-홍삼 복합 발효물의 산화적 손상 억제 효과를 평가하고자 $H_2O_2$로 산화적 스트레스를 유도시킨 C2C12 근육세포에 홍경천-홍삼 복합 발효물의 처리한 후, 세포의 morphology, cell viability 및 항산화 효소들의 유전자 발현 양상을 비교, 분석하였다. 홍경천-홍삼 복합 발효물은 C2C12 근육세포의 cell viability를 유의적으로 증가시켰으며, Cu/Zn-SOD, Mn-SOD 및 GPx 등과 같은 세포내 항산화 효소의 발현을 증가시킬 뿐만 아니라, 근육세포 분화의 주요 전사인자인 Myo D의 발현 또한 증가시키는 것으로 나타났다. 이상의 결과로, 홍경천-홍삼 복합 발효물은 세포내 항산화 효소 시스템을 증가시켜 외부로부터의 산화적 손상에 대한 방어효능을 갖는 것으로 나타났으며, 향후 in vivo 시스템 이용한 추가적인 연구가 수행된다면, 홍경천-홍삼 복합 발효물을 이용한 항피로 건강기능식품의 소재개발이 가능할 것으로 판단된다.

• 대한토목학회논문집
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• 제12권3호
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• pp.115-125
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• 1992

광양만의 지형변화에 따른 유황변화를 수심방향으로 적분된 2 차원 조석방정식을 사용하여 검토하였다. 연구결과 부두건설에 따른 해수면적의 감소로 인해 광양만으로 유입하는 조석량이 작아졌으며, 이로 인해 묘도를 중심으로한 만 외측에서는 조위차가 약간 커졌으며, 만내측에서는 전반적으로 수위가 하강한 것으로 나타났고, 특히 간조시의 수위 하강현상이 뚜렷하게 나타났다. 유속의 변화양상은 광양만 전체에 걸쳐 건설전 보다 작아졌으나, 광양동천에서 만으로 유입되는 수로에서는 수로 단변의 축소로 유속이 증가한 것으로 나타났다. 또한 대조기 시에 광양만으로 유입하는 수어천, 광양동천, 그리고 만의 외부경계인 섬진강으로 부터의 홍수량을 100 년 빈도로 한 결과, 섬진강하구에서는 약 1.2 m 그리고 광양만 내측에서는 약 0.3 m 의 수면상승을 초래하는 것으로 나타났다.

• Clinical and Experimental Reproductive Medicine
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• 제38권3호
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• pp.142-147
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• 2011

Objective: This study was performed to evaluate testicular sperm chromatin condensation using aniline blue-eosin (AB-E) staining and its effects on IVF-ET. Methods: Chromatin condensation was analyzed using AB-E staining in 27 cases of testicular sperm extraction. There were 19 cases of obstructive azoospermia (OA) and 8 cases of non-obstructive azoospermia (NOA) in IVF-ET. Mature sperm heads were stained red-pink whereas immature sperm heads were stained dark blue. The percentage of sperm chromatin condensation was calculated from the ratio of the number of red-pink sperm to the total number of sperm analyzed. Results: The overall percentages of chromatin condensation in OA and NOA were $31.1{\pm}11.2%$ and $26.3{\pm}14.4%$, respectively. The fertilization rate was significant higher in OA than NOA ($p$ <0.05); however, the rates of good embryos and clinical pregnancy did not show statistical differences. In OA and NOA, statistical differences were not observed in the rate of chromatin condensation, fertilization, good embryos, and clinical pregnancy between the pregnant group and non-pregnant group. Conclusion: Chromatin condensation is less stable than OA and showed a low fertilization rate in NOA. While there were no significant differences in chromatin condensation results between NOA and OA, we propose that a pattern of decreased chromatin condensation in NOA is one of the factors of low fertilization results requiring further study.

• Nutritional Sciences
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• 제8권2호
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• pp.133-139
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• 2005

Objective: The purpose of this study was to determine serum antioxidant nutrients and the relationship between serum antioxidants and risks of chronic diseases in obese Korean children Methods: Normal weight Korean school children (0=170), mean age of 11.5$\pm$1.5, and obese (body fat mass > $28\%$) children (0=176), mean age of 11.0$\pm$1.8, were recruited Fat mass ($\%$) was determnined by Bioelectrical Impedance (BEI), and body mass index (BMI) was calculated Fasting blood was collected to measure serum antioxidant nutrients, vitamin A, vitamin E and zinc. Serum lipid profiles including total cholesterol (TC), high density cholesterol (HDL) and triglyceride (TG), and blood glucose, glutamic oxaloacetic transaminase (GOT), and glutamic pyruvic transaminase (GPI) were also determined. Differences in serum blood measurements between obese and normal children were assessed by independent t test. Pearson's correlation analysis was used to determine the relationship between variables. Results: Blood glucose, GPT, total cholesterol, and triglycerides concentrations were significantly higher among obese boys, compared to normal boys (p<005). Significantly lower concentrations of serum vitamin E, after adjustment for TG and TC, was shown in obese boys (0.26 mg/mg) and obese girls (0.31 mg/mg), compared to normal boys (0.36 mg/mg) and girls (0.38 mg/mg) (p<0.05). Fat mass ($\%$) was negatively con-elated with serum vitamin A and vitamin E. Conclusion: Obese Korean children showed insufficient serum vitamin E concentration and increased risk for diabetes, atherosclerosis, and liver disease. Since lower vitamin E concentration was negatively con-elated with atherogenic index, improved vitamin E status in children may decrease the risk of atherosclerosis later in life.

• Journal of Animal Science and Technology
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• 제65권2호
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• pp.311-323
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• 2023

Beef consumers valued meat quality traits such as texture, tenderness, juiciness, flavor, and meat color that determining consumers' purchasing decision. Most research on meat quality has focused on marbling, a key characteristic related to meat eating quality. However, other important traits such as meat texture, tenderness, and color have not much studied in cattle. Among these traits, meat tenderness and texture of cattle are among the most important factors affecting quality evaluation of consumers. Collagen is the main component of connective tissues.It greatly affects meat tenderness. The objective of this study was to determine significant variants and candidate genes associated with collagen contents trait (total collagen) through genome-wide association studies (GWAS). Phenotypic and genomic data from 135 Hanwoo were used. The BLUPF90 family program and GRAMMAR method for GWAS were applied in this study. A total of 73 potential single nucleotide polymorphisms (SNPs) showed significant associations with collagen content. They were located in or near 108 candidate genes. TMEM135 and ME3 genes were identified to have the most significant SNPs associated with collagen contents trait. Data indicated that these genes were related to collagen. Biological processes and pathways for the prediction of biological functions of candidate genes were confirmed. We found that candidate genes were involved in positive regulation of CREB transcription factor activity and actin cytoskeleton related to tenderness and texture of beef. Three genes (CRTC3, MYO1C and MYLK4) belonging to these biological functions were related to tenderness. These results provide a basis for improving genomic characteristics of Hanwoo for the production of tender beef. Furthermore, they could be used they could be used as an index to select desired traits for consumers.

• 대한영양사협회학술지
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• 제2권1호
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• pp.69-80
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• 1996

This study was performed to investigate the food preference trends of the children according to age increase and change of the times. The subjects were 1,450 children who are fifth grade of primary school and 2,000 juveniles who are senior high school in 1993. This survey data were compared with the Food preference study of the primary school aged children in 1987.' The results of this study can be summarized as follows 1. State of the general taste The subject had a high preferences to bulgogi(roast beef), panbroiled cuttlefish, steamed egg, fried sausage and donuts among the all sorts of 165 principal and subsidiary foods. But, fried beef liver, pancake, sweet potato with syrup, spinach soup and boiled rice with red bean didn't suit for their taste. Compared with survey data done in 1987, in present study significantly increased preferences to steamed food, pan frying and parboiled vegetables were shown. Particularly, food preference was changed with the cooking methods rather than materials. 2. Differences of the preference according to change of the times In present study, except the rice cakes preferences to all sorts of foods were improved and markedly increased preferences to steamed food, parboiled vegetables and mixed with seasonings were observed. Compared with 87's study deviation of the preference to cooking materials was decreased considerably. Preferences to salty tasted foods as like as stew and salted food were low no better than before. 3. Changes of preference according to age increase Among the principal foods, increased preferences to boiled rice and cereals were shown but to one-dish meal, bread and rice cake were decreased. Among the subsidiary foods, significantly decreased preference to frying was observed. Irrespectively of the cooking methods, preferences to fish and vegetables were improved. And in the frying and panbroiled foods, deviation of preferences to cooking materials were considerable, which means the fixation of food behavior.

• 보건행정학회지
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• 제27권1호
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• pp.63-74
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• 2017

Background: This study aims to analyze quality of and satisfaction with Korea medical services and identify factors affecting medical service satisfaction, revisit, and recommendation intention among international patients. Methods: Secondary analysis of survey data conducted by Korea Health Industry Development Institute from June 10th to July 17th in 2013 was done using multiple regression and logistic regression analysis. The 191 international patients from 9 medical institutions in Seoul were enrolled. Results: The results showed that international patients were satisfied with 85.6 points out of 100.0 points. International patients appraised higher in staff service rather than other services. Factors influencing medical service satisfaction were gender, religion, medical specialty, length of stay, and quality of medical services. Quality of medical service explained 29.8% of medical service satisfaction and especially, 'doctor's care' and 'communication and patient respect' were significantly related to medical service satisfaction. Medical specialty had a significant influence on revisit intention. There were no statistically significant influencing factors of recommendation intention. Additionally, more satisfied patients were associated with higher revisit and recommendation intention. Conclusion: This study implies that quality of medical services is a critical factor for patient satisfaction and that satisfaction with medical services is an important factor for increasing revisit and recommendation intention among international patients. In addition, health care providers should consider cultural differences to enhance satisfaction with medical services for international patients. Therefore, multidimensional strategy is required to strengthen the cultural competency of healthcare providers.

• 한국의료질향상학회지
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• 제12권1호
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• pp.92-102
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• 2006

Background : Most hospitalized children will experience physical pain as well as psychological distress. Painful procedure can increase anxiety and fear of pediatric patients and their parents who do not have understanding logical of their disease and hospitalization. This study attempted to identify pain reduction in related to therapeutic intervention by age and environmental improvement. Methods : A total of 194 hospitalized children and their parents were investigated. Data collection period was 3 months from March to May 2004. Four instruments were used to collect the data : Faces Pain Rating Scale(FPRS), Heart rate, Oxygen saturation and Pain behavioral check list. The data were analyzed by a SPSS program and tested x2-test, t-test, ANCOVA. Results : 1. Age from 0 to 3, the Heart rate, FPRS, Oxygen saturation and Pain behavioral check list were significantly different in theraputic intervention group when compare to control group. 2. Age from 4 to 6, FPRS, Oxygen saturation and Pain behavioral check list were significantly different in theraputic intervention group when compare to control group. But the heart rate were not significantly different when compare to control group. 3. Age from 7 to 9, FPRS and Pain behavioral check list were significantly lower in therapeutic intervention group when compare to control group but Heart rate and Oxygen saturation were not significantly different when compare to control group. Conclusion : The results of this study concludes that most children experience acute pain during IV therapy and it can be reduced by age specific therapeutic intervention and by change of surrounding environment.

• 한국조경학회지
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• 제28권3호
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• pp.25-38
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• 2000

The research follows several steps. First, the chinese 'WangSung' and 'KungSi' System are verified positively. Next, the structure of palace in Choson Dynasty is deduced based on those chinese systems. Finally, the common system that is also applied in other government-operated spaces is found. The result can be summarized as follows. It is clarified from reviewing the chinese 'WangSung' and 'KungSil' Systems that the 'OyoiCho' is located in 'WhangSung(the imperial city) but out of' KungSung(the palace). Therefore, the research points out that all sort of theories explaining the 'OyoiCho' of Choson Dynasty is a space of 'in-place' are false. The palace system of Choson dynasty seeks the substantiality grounded on the substantial function of 'SamCho(three spaces)' rather than its strict principle dividing main spaces by several doors-'KungMoon' Moreover, it is also certified that the 'ChonChoHooChim' system, literally the political court is located at the front and the private section is at the other(back) side, is directly applied on the palace of Choson Dynasty. This idea has been developed into 'inner and outer' concept and repressed in palace as the 'OyoiChon(outer palace) and NaeChon(inner palace)' concept. conclusion, the research suggests that the dual concept in space such as 'ChonHoo(front and back) and 'NaeOyoi(inner and outer)' basically comes from 'Eum Yang' theory and influences in building other government-operated spaces: for example 'ChongMyo(the royal ancestors shrine)', 'SoWon(a private school of Choson dynasty), 'HyangKyo(a local school annexed to the Confucian shrine)' and 'KwanAh(a governmet agency)'

• 한국전통조경학회지
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• 제29권1호
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• pp.121-130
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• 2011

본 연구는 조선 후기 개인문집 속에 묘사된 경관 관련 문헌을 조사 발굴하여 장소를 찾고, 그 속에 묘사된 대상지와 주변경관요소들을 분석하여 실제의 경관을 찾을 수 있는 가능성을 확인해 보는 기초연구로서, 대상지는 조선 후기 학자 최동집의 대암선생문집에 묘사된 농연서당십경에 대한 각 경관요소 및 장소를 찾아보는 것이다. 연구내용은 1) 대암 최동집과 대암선생문집을 정리한 후손 백불암 최흥원의 배경 및 농연서당에 대하여 이론적 고찰을 하였고, 2) 문헌자료 및 현장조사를 통해서 농연서당의 위치 및 장소를 파악하였으며, 3) 그 장소에서 농연서당십경에 대한 경관요소 및 분포관계 그리고 의미를 분석하였다. 고찰을 통해 농연서당의 배치와 방향에 대한 의미를 되짚고, 정원조성관련 기록을 확인하였으며, 지속적인 연구를 위한 방향을 제시하였다.